Abstract：
:The effects of substantia nigra (SN) stimulation on the activity of the nucleus ventralis lateralis of the thalamus (VL) have been studied. The VL cells were identified as relay or non-relay cells among the cerebellothalamocortical pathway on the basis of orthodromical activation from the cerebellum and antidromical activation from the cortex. Certain experiments were performed after wide pericruciate decortication in order to eliminate the response due to unavoidable activation of corticofugal fibers. These results show that nigrothalamic neurons exert an inhibitory effect on VL cells. This inhibition was observed on the relay as well as on non-relay cells and was strong enought to suppress the cerebellar monosynaptic excitatory input. Thus the SN can modulate the information running along the cerebellothalamocortical pathway. The topographic localization of inhibited cells suggests that the SN controls the activity of the thalamic neurons which interfere with axial and proximal musculature.
journal_name
Brain Resjournal_title
Brain researchauthors
Deniau JM,Lackner D,Feger Jdoi
10.1016/0006-8993(78)90793-xsubject
Has Abstractpub_date
1978-04-21 00:00:00pages
27-35issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(78)90793-Xjournal_volume
145pub_type
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