Abstract：
:The distribution of calcitonin gene-related peptide (CGRP) and its binding sites in the bulbocavernosus, a striated muscle, are reported. We used immunohistochemistry and [125I]CGRP autoradiography. The pattern of [125I]CGRP binding was restricted to a discrete band that coincides with the distribution of end-plates in this muscle as determined by CGRP immunohistochemistry and acetylcholinesterase staining. CGRP has been shown to increase the level of acetylcholine receptor (AChR) alpha-subunit mRNA. The role of CGRP as the endogenous factor by which motoneurons regulate the expression of junctional AChR is discussed.
journal_name
Brain Resjournal_title
Brain researchauthors
Popper P,Micevych PEdoi
10.1016/0006-8993(89)91064-0subject
Has Abstractpub_date
1989-09-04 00:00:00pages
180-6issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(89)91064-0journal_volume
496pub_type
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