Dorsal and ventral hippocampal cholinergic systems modulate anxiety in the plus-maze and shock-probe tests.

abstract：:Respiration related units ( RRU ) were recorded in the brainstem of cats with spinal transection at the C7-Th 1 level and breathing N2O. The proportion of RRU in several structures was compared in control and in 3 experimental groups: (1) paralyzed with gallamine triethiodide; (2) vagotomized; and (3) both vagotomized...

journal_title：Brain research

authors： Caille D,Foutz AS,Vibert JF,Hugelin A

更新日期：1984-05-07 00:00:00

abstract：:Up to today, the neuronal bases of activating and establishing a memory trace are not well understood. Several findings point towards the idea that the activation of an engram is mirrored in induced oscillatory bursts in the gamma frequency range (> 20 Hz; induced gamma band responses; iGBRs). In the present study, we...

journal_title：Brain research

authors： Gruber T,Müller MM

更新日期：2006-06-30 00:00:00

abstract：:The actions of pentobarbital (PB) and diphenylhydantoin (DPH) have been studied on neurons of dorsal root ganglia from adult rats. At anesthetic level (i.e. 1--2 x 10(-4) M), PB greatly enhanced neuronal responses to gamma-aminobutyric acid (GABA); at 10(-3) M PB caused a small depolarization and profoundly attenuated...

journal_title：Brain research

authors： Connors BW

更新日期：1981-03-02 00:00:00

abstract：:Astrocytes provide structural, trophic and metabolic support to neurons and modulate synaptic activity. Under physiological conditions, neuronal-derived nitric oxide (NO) plays an important role in the modulation of a variety of central nervous system (CNS) functions. NO, although short lived, can travel sufficient di...

journal_title：Brain research

authors： Nanetti L,Vignini A,Moroni C,Pessina GP,Mazzanti L

更新日期：2004-09-10 00:00:00

abstract：:Homogenates of rat ventral and dorsal spinal cords were subjected to differential and gradient centrifugation on linear sucrose gradients following lysis of a synaptosomal fraction. The distribution of calcitonin gene-related peptide (CGRP) and substance P (SP) in dorsal spinal cord as well as the distribution of sero...

journal_title：Brain research

authors： Fried G,Franck J,Brodin E,Born W,Fischer JA,Hiort W,Hökfelt T

更新日期：1989-10-16 00:00:00

abstract：:Although transsynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characterized, several methodological issues related to central application of this tracer have not been addressed. In the present study, we addressed the following three issues by using microinjection of a cockta...

journal_title：Brain research

authors： Chen S,Yang M,Miselis RR,Aston-Jones G

更新日期：1999-08-14 00:00:00

abstract：:Patients with subcortical ischemic vascular disease (SIVD) may hold a high risk of cognitive impairment (CI) by affecting the functional connectivity (FC) of resting-state networks (RSNs). Current studies have mainly focused on the patients with CI but have ignored the prodromal stage when people suffered subcortical ...

journal_title：Brain research

authors： Liu X,Chen L,Cheng R,Luo T,Lv F,Fang W,Gong J,Jiang P

更新日期：2019-07-15 00:00:00

abstract：:gamma-Aminobutyric acid (GABA), pentobarbital and ethanol were applied by bath superfusion to rat locus coeruleus (LC) neurons in a brain slice preparation. The GABA-induced current and conductance increase was measured with single-electrode voltage clamp. Pentobarbital potentiated the GABA-induced current and conduct...

journal_title：Brain research

authors： Osmanović SS,Shefner SA

更新日期：1990-05-28 00:00:00

abstract：:Luteinizing hormone (LH) secretion during the reproductive cycle and in ovariectomized (OVX) rats is pulsatile and this pattern of secretion is determined by intermittent discharges of LH-releasing hormone (LHRH) into the hypophysial portal vessels. LHRH secretion is probably controlled by prior pulsatile norepinephri...

journal_title：Brain research

authors： Anselmo-Franci JA,Rocha-Barros VM,Franci CR,McCann SM

更新日期：1999-06-26 00:00:00

abstract：:Rat pinealocytes use L-glutamate as a modulator for melatonin synthesis. Upon binding of L-glutamate to the class II metabotropic glutamate receptor, norepinephrine (NE)-dependent formation of cAMP was inhibited, resulting in decreased serotonin-N-acetyltransferase (NAT) activity and melatonin output. Although L-gluta...

journal_title：Brain research

authors： Ishio S,Yamada H,Craft CM,Moriyama Y

更新日期：1999-12-11 00:00:00

abstract：:Brain-derived angiotensin II (ANG II) and prostaglandins have important roles in the regulation of body fluid and blood pressure homeostasis. In the present studies we investigated the central interactions between these two neurochemical products in regulating the hypothalamo-neurohypophysial system during dehydration...

journal_title：Brain research

authors： Kadekaro M,Terrell ML,Bui V,Summy-Long JY

更新日期：2001-01-19 00:00:00

abstract：:Samples of 14 brains of autopsied patients suffering from dementia of the Alzheimer type were examined. In Congo red-hemalum stained 14-microns-thick sections of the hippocampus 15 tangle-bearing and 25-30 unaffected nerve cells of area CA1 per case were measured for cell size and nucleolar size utilizing an interacti...

journal_title：Brain research

authors： Gertz HJ,Schoknecht G,Krüger H,Cervos-Navarro J

更新日期：1989-05-22 00:00:00

abstract：:Administration of methamphetamine (15 mg/kg) to adrenalectomized rats significantly decreased hippocampal type I and II corticosteroid receptors as well as type II receptors in the striatum. Type II receptors in the frontal cortex and hypothalamus were unaffected by methamphetamine administration. Pretreatment with MK...

journal_title：Brain research

authors： Lowy MT

更新日期：1990-11-19 00:00:00

abstract：:Examination of the projection from area 2 of the sensory cortex to the motor cortex revealed substantial changes following lesion of the ventrolateral nucleus of the thalamus. These observed changes were as follows. (1) The polarity of the evoked potentials elicited by area 2 stimulation reversed in the depth of the m...

journal_title：Brain research

authors： Asanuma H,Kosar E,Tsukahara N,Robinson H

更新日期：1985-10-14 00:00:00

abstract：:We previously reported that the level of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) alpha and beta proteins increases with postnatal age. In the present study, we investigated the developmental changes in whole protein substrates of CaM kinase II as compared with those of cAMP-dependent protein kinase...

journal_title：Brain research

authors： Sugiura H,Yamauchi T

更新日期：1994-10-03 00:00:00

abstract：:The climbing fiber input to the cerebellar cortex was destroyed using both electrolytic and chemical (3-acetylpyridine) lesions. The long-term effects of climbing fiber deafferentation on the ansiform lobule of weanling and adult rats were examined at both the light and electron microscopic levels. Image analysis of G...

journal_title：Brain research

authors： Anderson WA,Flumerfelt BA

更新日期：1986-09-24 00:00:00

abstract：:The intercollicular pathway of the rat was studied using autoradiographic (ARG) and horseradish peroxidase (HRP) tracing techniques. The HRP experiments demonstrated that the cells of origin of the intertectal pathway were located primarily in the rostral stratum griseum intermediale ( SGI ), stratum album intermedium...

journal_title：Brain research

authors： Yamasaki DS,Krauthamer G,Rhoades RW

更新日期：1984-05-23 00:00:00

abstract：:Effects of inhibition of nitric oxide (NO) synthesis on the cerebrovascular autoregulatory vasodilator response to hypotension were studied in conscious rats. Cerebral blood flow (CBF) was determined with [14C]iodoantipyrine in a saline-treated control group and in three groups following inhibition of NO synthase acti...

journal_title：Brain research

authors： Takahashi S,Cook M,Jehle J,Kennedy C,Sokoloff L

更新日期：1995-04-24 00:00:00

abstract：:Five normal rats and four rats with bilateral lesions of auditory cortex were tested by the conditioned suppression procedure to determine their abilities to discriminate between spatially separated sound sources. The discrimination involved detection of a change in location of a train of clicks from a speaker on the ...

journal_title：Brain research

authors： Kelly JB,Glazier SJ

更新日期：1978-04-28 00:00:00

abstract：:Previous results indicate that the dopaminergic system in the anterior medial zona incerta (ZI) exerts a stimulatory effect on LH release. In this report changes in dopamine (DA) turnover in the ZI, preoptic area (POA) and arcuate/median eminence area (ARC/ME) (as assessed by the rate of decline in DA concentration af...

journal_title：Brain research

authors： MacKenzie FJ,James MD,Wilson CA

更新日期：1988-03-15 00:00:00

abstract：:Nitric oxide (NO) is an endothelium-derived relaxing factor and its main mechanism of action is activation of soluble guanylyl cyclase. NO and NO-related compounds have been reported to affect several neuronal functions in the central nervous system. In this study, we investigated the effects of NO donors (sodium nitr...

journal_title：Brain research

authors： Suzuki T,Nakajima K,Fujimoto K,Fujii T,Kawashima K

更新日期：1997-06-20 00:00:00

abstract：:The aim of this study was to evaluate spatial organization of hyperactive microglial cells in trigeminal spinal subnucleus caudalis (Vc) and upper cervical spinal cord (C1), and to clarify the involvement in mechanisms underlying orofacial secondary hyperalgesia following infraorbital nerve injury. We found that the h...

journal_title：Brain research

authors： Shibuta K,Suzuki I,Shinoda M,Tsuboi Y,Honda K,Shimizu N,Sessle BJ,Iwata K

更新日期：2012-04-27 00:00:00

abstract：:We have shown that, when an amyloid-beta peptide (Abeta) overproducing transgenic mouse model (PSAPP) of Alzheimer's disease (AD) is treated with a depleting antibody against CD40L, it causes marked attenuation of Abeta pathology associated with decreased amyloidogenic processing of amyloid precursor protein (APP) and...

journal_title：Brain research

authors： Todd Roach J,Volmar CH,Dwivedi S,Town T,Crescentini R,Crawford F,Tan J,Mullan M

更新日期：2004-07-23 00:00:00

abstract：:Pregabalin is useful for treating neuropathic pain, but known to increase body weight as a side effect. To investigate the mechanism of this increase in body weight, we focused on dopamine in the lateral hypothalamus (LH) and examined the effects of pregabalin on dopamine levels in the LH and food intake. The dopamine...

journal_title：Brain research

authors： Ikeda H,Yonemochi N,Ardianto C,Yang L,Kamei J

更新日期：2018-12-15 00:00:00

abstract：:The mechanism of the Ca2+-dependent stimulation of neurotransmitter release by 4-aminopyridine in synaptosomes was studied. The stimulation of gamma-[3H]aminobutyric acid and [3H]acetylcholine release by 4-aminopyridine was not significantly affected either by tetrodotoxin or by the absence of Na+ in the medium, where...

journal_title：Brain research

authors： Tapia R,Sitges M,Morales E

更新日期：1985-12-30 00:00:00

abstract：:Considerable knowledge exists concerning the events mediating neuron death following a necrotic insult; prompted by this, there have now been successful attempts to use gene therapy approaches to protect neurons from such necrotic injury. In many such studies, however, it is not clear what sequence of cellular events ...

journal_title：Brain research

authors： Gupta A,Ho DY,Brooke S,Franklin L,Roy M,McLaughlin J,Fink SL,Sapolsky RM

更新日期：2001-07-20 00:00:00

abstract：:In acute cats deeply anesthetized with Nembutal, monosynaptic excitatory postsynaptic potentials (EPSPs) triggered by stimulation of the ventrolateral (VL) thalamic nucleus and the pes pedunculus were recorded in large pyramidal tract cells (PT cells). Deep anesthesia, low intensities of stimulation and an averaging t...

journal_title：Brain research

authors： Deschênes M,Labelle A,Landry P

更新日期：1979-01-05 00:00:00

abstract：:Both clinical and experimental studies have indicated that depression and depression-like animal conditions are associated with disruption of the intrinsic plasticity of the brain, resulting in neuronal atrophy. However, little is known about the brain glia in these conditions. Early life stress in the form of infant ...

journal_title：Brain research

authors： Leventopoulos M,Rüedi-Bettschen D,Knuesel I,Feldon J,Pryce CR,Opacka-Juffry J

更新日期：2007-04-20 00:00:00

abstract：:Astrocytes associated with beta-amyloid (Aβ)-deposited senile plaques are a common neuropathological feature of Alzheimer's disease (AD). There is little doubt that the association of Aβ with the major component in the central nervous system cells significantly influences disease progression, however, the molecular me...

journal_title：Brain research

authors： Satoh K,Akatsu H,Yamamoto T,Kosaka K,Yokota H,Yamada T

更新日期：2012-03-02 00:00:00

abstract：:Our recent researches have identified increased expression of miR-21-5p in rats brain following traumatic brain injury (TBI), which protected against blood-brain barrier (BBB) damage. To further study the mechanism underlying the role of miR-21-5p on alleviating BBB damage after TBI, we performed the scratch injury mo...

journal_title：Brain research

authors： Ge X,Huang S,Gao H,Han Z,Chen F,Zhang S,Wang Z,Kang C,Jiang R,Yue S,Lei P,Zhang J

更新日期：2016-11-01 00:00:00