Transneuronal retrograde degeneration in the cat retina following neonatal ablation of visual cortex.

abstract：:The present study is a determination of the numbers of axons in the sural nerve and nerve to the medial gastrocnemius muscle following section and regeneration of the sciatic nerve in the rat. The data indicate that there is a significant increase in both myelinated and unmyelinated axons in the nerve to the medial ga...

journal_title：Brain research

authors： Jenq CB,Coggeshall RE

更新日期：1984-03-12 00:00:00

abstract：:Excitotoxic effects leading to neuronal cell degeneration are often accompanied by a prolonged increase in the intracellular level of Ca(2+) ions and L-glutamate-induced toxicity is assumed to be mediated via a Ca(2+)-dependent mechanism. Due to their buffering properties, EF-hand Ca(2+)-binding proteins (CaBPs) can a...

journal_title：Brain research

authors： D'Orlando C,Celio MR,Schwaller B

更新日期：2002-08-02 00:00:00

abstract：:Rats were anesthetized with a continuous infusion of pentobarbital. First we showed that electroacupuncture (EA) suppressed the tail flick nociceptive reflex. Naltrexone (a long acting opiate antagonist) was given either intravenously or intrathecally to attempt to block this EA effect. The naltrexone prevented this E...

journal_title：Brain research

authors： Pomeranz B,Bibic L

更新日期：1988-06-14 00:00:00

abstract：:The current study revisited the question of whether there are brain mechanisms specific to divided attention that differ from those used in selective attention. Increased neuronal activity required to simultaneously process two stimulus dimensions as compared with each separate dimension has often been observed, but r...

journal_title：Brain research

authors： Hahn B,Wolkenberg FA,Ross TJ,Myers CS,Heishman SJ,Stein DJ,Kurup PK,Stein EA

更新日期：2008-06-18 00:00:00

abstract：:The visual system in the pigeon is composed of the tectofugal, thalamofugal and accessory optic pathways. Though their anatomy and physiology have been extensively studied, the functional interactions between these pathways are largely unknown. The present study shows by using multiple electrophysiological techniques ...

journal_title：Brain research

authors： Cao P,Yang Y,Yang Y,Wang SR

更新日期：2006-01-19 00:00:00

abstract：:Time-course expression of Bax and Bcl-2 proteins, identified as apoptosis-regulating molecules, was assessed in gerbil hippocampus following transient forebrain ischemia. Brain sections from animals sacrificed at 48, 72, 96 h and 7 days following 5 min ischemia were immunohistochemically evaluated using polyclonal ant...

journal_title：Brain research

authors： Hara A,Iwai T,Niwa M,Uematsu T,Yoshimi N,Tanaka T,Mori H

更新日期：1996-03-04 00:00:00

abstract：:Recent studies suggest that both sex and cerebral hemisphere influence brain mechanisms associated with emotional memory. Here we used evoked potentials to examine the influence of sex and hemisphere on brain responses to emotional stimuli. Given that the P300 component of the event-related brain potential (ERP) is co...

journal_title：Brain research

authors： Gasbarri A,Arnone B,Pompili A,Pacitti F,Pacitti C,Cahill L

更新日期：2007-03-23 00:00:00

abstract：:The amplitude of anterior neocortical EEG slow-waves (0.5-4 Hz) measured during quiet waking, drowsy (WS) and synchronized sleep (S) states showed slow rhythmic oscillations in WS and S similar to those previously reported in midbrain reticular neurons (periods of 8-12 s). Abrupt changes in slow rhythms of unit discha...

journal_title：Brain research

authors： Oakson G,Steriade M

更新日期：1983-06-20 00:00:00

abstract：:Changes in the activity and amount of the neurotransmitter synthesizing enzyme tyrosine hydroxylase (TH) were measured in dopaminergic (DA) neurons of the A10-mesolimbic system of the rat following electrolytic lesions of their axons. Unilateral hypothalamic lesions in close proximity to the cell bodies resulted, with...

journal_title：Brain research

authors： Gilad G,Reis DJ

更新日期：1978-06-23 00:00:00

abstract：BACKGROUND:Sex-specific trajectories in white matter development during adolescence may help explain cognitive and behavioral divergences between males and females. Knowledge of sex differences in typically developing adolescents can provide a basis for interpreting sexual dimorphisms in abilities and actions. METHOD:...

journal_title：Brain research

authors： Bava S,Boucquey V,Goldenberg D,Thayer RE,Ward M,Jacobus J,Tapert SF

更新日期：2011-02-23 00:00:00

abstract：:In this report we have described several aspects of glial development in cultures containing dissociated DRG neurons and glial cells obtained from dissociated spinal cord at least a week prior to the onset of in vivo myelination. With time in culture the dissociated neurons and glia interact and become organized into ...

journal_title：Brain research

authors： Wood PM,Williams AK

更新日期：1984-02-01 00:00:00

abstract：:The therapeutic use of neurotrophic factors to treat neurodegenerative disorders, including Alzheimer's disease, is considered feasible. Magnolol and honokiol, constituents of the Magnolia plant, are small organic compounds with neurotrophic activity. We investigated whether magnolol and honokiol can prevent age-relat...

journal_title：Brain research

authors： Matsui N,Takahashi K,Takeichi M,Kuroshita T,Noguchi K,Yamazaki K,Tagashira H,Tsutsui K,Okada H,Kido Y,Yasui Y,Fukuishi N,Fukuyama Y,Akagi M

更新日期：2009-12-11 00:00:00

abstract：:Acuity assessments on lateral geniculate X-cells in 8 monocularly deprived cats indicated that deprived cells had significantly lower acuities than non-deprived cells. Within deprived laminae, cells having low acuity were intermixed with cells having normal acuity. Deprivation effects were clearly evident in both A an...

journal_title：Brain research

authors： Mower GD,Christen WG

更新日期：1982-03-01 00:00:00

abstract：:The present study was designed to investigate the distribution of serotonin 5-HT1A receptor protein (5-HT1A-immunoreactivity) and its localization within cortical pyramidal neurons of the rat cingulate cortex. This experimental direction was inspired by recent data showing the role of 5-HT1A receptors in the pathology...

journal_title：Brain research

authors： Czyrak A,Czepiel K,Maćkowiak M,Chocyk A,Wedzony K

更新日期：2003-10-31 00:00:00

abstract：:Anterograde and retrograde tracing experiments employing WGA-HRP were used to identify an auditory projection area within the frontal telencephalon of the pigeon. The projection originates in a nucleus of the lateral lemniscus, travels with the quintofrontal tract and terminates within nucleus basalis. The location of...

journal_title：Brain research

authors： Arends JJ,Zeigler HP

更新日期：1986-11-29 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) promotes survival of injured dopaminergic nigrostriatal neurons of the adult rodent substantia nigra pars compacta, as well their development in vitro. BDNF deficiency may play a role in Parkinson's disease, as the surviving dopaminergic nigrostriatal neurons have reduced level...

journal_title：Brain research

authors： Baker SA,Stanford LE,Brown RE,Hagg T

更新日期：2005-03-28 00:00:00

abstract：:Effects of protein kinase C (PKC) activation on the function of the GABA/benzodiazepine receptor-chloride complex were analyzed by quantitative autoradiography using [3H]muscimol, [3H]flunitrazepam and [35S]TBPS in rat brain slices. The density of [3H]muscimol binding was highest in cerebellar granular layers and high...

journal_title：Brain research

authors： Oh S,Jang CG,Ma T,Ho IK

更新日期：1999-12-11 00:00:00

abstract：:S-allyl cysteine (SAC), a sulfur containing amino acid derived from garlic, has been reported to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was designed to examine the pre-treatment effects of SAC on cognitive deficits and oxidative damage in the hippocampus of intracerebroven...

journal_title：Brain research

authors： Javed H,Khan MM,Khan A,Vaibhav K,Ahmad A,Khuwaja G,Ahmed ME,Raza SS,Ashafaq M,Tabassum R,Siddiqui MS,El-Agnaf OM,Safhi MM,Islam F

更新日期：2011-05-10 00:00:00

abstract：:Cytotoxic effects of L-glutamate and related compounds were investigated on rat glioma C6 cells in vitro. Within 12-24 h, addition of glutamate to the culture medium, resulted in degeneration of the C6 cells. The ED50 for glutamate-induced damage was about 4 mM. Seventeen structural analogues of glutamate, including a...

journal_title：Brain research

authors： Kato S,Higashida H,Higuchi Y,Hatakenaka S,Negishi K

更新日期：1984-06-15 00:00:00

abstract：:Fetal exposure to diazepam (DZ), a positive modulator of GABA(A) receptors and an agonist at mitochondrial benzodiazine receptors, induces long-term neural and behavioral effects. This study evaluated whether the early manipulation influenced the normal development of brain levels of neurosteroids or altered steroid a...

journal_title：Brain research

authors： Kellogg CK,Kenjarski TP,Pleger GL,Frye CA

更新日期：2006-01-05 00:00:00

abstract：:The role of gangliosides in preventing neuronal degeneration was examined in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse parkinsonian model. Intraventricular injections of a ganglioside mixture prior to MPTP treatment reduced MPTP's toxicity on tyrosine hydroxylase-positive neurons in the subst...

journal_title：Brain research

authors： Gupta M,Schwarz J,Chen XL,Roisen FJ

更新日期：1990-09-17 00:00:00

abstract：:Astrocytes exhibit an important role in neural lipid metabolism for the regulation of energy balance to supply fatty acids (FAs) and ketone bodies to other neural cells. Lipid droplets (LDs) consisting of neutral- and phospho-lipids increase in the brains of patients with neurodegenerative diseases, such as Alzheimer'...

journal_title：Brain research

authors： Nakajima S,Gotoh M,Fukasawa K,Murakami-Murofushi K,Kunugi H

更新日期：2019-12-15 00:00:00

abstract：:Extracellular field recordings were made in CA1 in the hippocampal explant cultures in oxygenated artificial cerebrospinal fluid. Schaffer collaterals were stimulated with 1-s trains of 60 Hz pulses every 10 min. Seizures were reliably elicited with progressive lengthening over 1-2 h. D-APV, an N-methyl-D-aspartate (N...

journal_title：Brain research

authors： Shin C,Tamaki Y,Wilson JT,Butler L,Sakaguchi T

更新日期：1992-08-28 00:00:00

abstract：:We used double-barreled pH-sensitive microelectrodes to study the mechanisms by which the intracellular pH is regulated in the connective glial cells of the medicinal leech. The experiments indicate that a Cl(-)- and HCO3(-)-dependent mechanism mediates some recovery from intracellular alkalosis even in the absence of...

journal_title：Brain research

authors： Szatkowski MS,Schlue WR

更新日期：1994-11-28 00:00:00

abstract：:Variations in cerebral blood flow and partial pressures of oxygen and carbon dioxide (pO2, pCO2) were studied in rabbits during short-duration (1 min) immobilization stress. The techniques used enabled us to determine these variables locally in the caudate nucleus in a continuous, simultaneous and quantitative fashion...

journal_title：Brain research

authors： Pinard E,Lacombe P,Reynier-Rebuffel AM,Seylaz J

更新日期：1985-08-12 00:00:00

abstract：:Environmental risk factors such as stressful experiences have long been recognized to affect seizure susceptibility, but little attention has been paid to the potential effects of improving housing conditions. In this study, we investigated the influence of an enriched environment on epileptogenesis. Epileptic suscept...

journal_title：Brain research

authors： Auvergne R,Leré C,El Bahh B,Arthaud S,Lespinet V,Rougier A,Le Gal La Salle G

更新日期：2002-11-08 00:00:00

abstract：:A comparison was made of the effects of left and right cerebral decortication on cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse. Natural killer cytotoxic activity was significantly reduced after right decortication, whereas left decortication led to a less pronounced, though still ...

journal_title：Brain research

authors： Belluardo N,Mudò G,Cella S,Bindoni M

更新日期：1990-08-06 00:00:00

abstract：:In order to study the effects of treatment with monosodium glutamate (MSG) during the neonatal period on the intrinsic circadian timekeeping system in rats, the locomotor activity of blinded MSG-treated and control (saline-treated) rats was analyzed with power spectral analysis and cross-correlation. In contrast to a ...

journal_title：Brain research

authors： Miyabo S,Yamamura I,Ooya E,Aoyagi N,Horikawa Y,Hayashi S

更新日期：1985-07-29 00:00:00

abstract：:The present study evaluated the ability of salicylic acid (SA) to attenuate long-term L-DOPA-induced 6-hydroxydopamine (6-OHDA) formation in the striatum of mice, and to protect against the resulting dopaminergic neurotoxicity. The production of 6-OHDA from dopamine in vitro from ferrous-ascorbate-dopamine (FAD) hydro...

journal_title：Brain research

authors： Borah A,Mohanakumar KP

更新日期：2010-07-16 00:00:00

abstract：:It has recently been shown that the lobules 9 and 10 of the cerebellum contain high densities of dopamine D3 receptors (and almost no D2 receptors [Bouthenet, M.L., Souil, E., Martres, M.P., Sokoloff, P., Giros, B. and Schwartz, J.C., Brain Res., 564 (1991) 203-219; Sokoloff, P., Giros, B., Martres, M.P., Bouthenet, M...

journal_title：Brain research

authors： Barik S,de Beaurepaire R

更新日期：1996-10-21 00:00:00