Abstract:
:We used double-barreled pH-sensitive microelectrodes to study the mechanisms by which the intracellular pH is regulated in the connective glial cells of the medicinal leech. The experiments indicate that a Cl(-)- and HCO3(-)-dependent mechanism mediates some recovery from intracellular alkalosis even in the absence of external Na+. This suggests the presence of Na(+)-independent Cl-/HCO3- exchange in the connective glial membrane. At alkaline pHi, this exchange most likely operates in the direction of net acid loading (i.e. HCO3- efflux).
journal_name
Brain Resjournal_title
Brain researchauthors
Szatkowski MS,Schlue WRdoi
10.1016/0006-8993(94)91144-4subject
Has Abstractpub_date
1994-11-28 00:00:00pages
1-4issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(94)91144-4journal_volume
665pub_type
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