Effects on the growth of damaged ganglion cell axons after peripheral nerve transplantation in adult hamsters.

abstract：:Leumorphin, an opioid peptide whose functions are unknown, is found in mammalian brain and pituitary and stimulates lordosis behavior in estrogen-treated female rats. To elucidate the role of leumorphin in the physiological control of female sexual behavior, the levels of immunoreactive (ir) leumorphin as well as ir d...

journal_title：Brain research

authors： Suda M,Nakao K,Sakamoto M,Morii N,Sugawara A,Imura H

更新日期：1986-05-28 00:00:00

abstract：:Bilateral removal of the cortical visual area in newborn cats produces degeneration of retinal ganglion cells. Measurements of over 4,000 cells and calculation of neuron densities from sample areas of retina in the adult show that the medium sized cell population in peripheral retina is reduced by 68%, whereas the pop...

journal_title：Brain research

authors： Pearson HE,Labar DR,Payne BR,Cornwell P,Aggarwal N

更新日期：1981-05-18 00:00:00

abstract：:The understanding of sarcasm reflects a complex process, which involves recognizing the beliefs of the speaker. There is a clear association between deficits in mentalizing, which is the ability to understand other people's behavior in terms of their mental state, and the understanding of sarcasm in individuals with a...

journal_title：Brain research

authors： Uchiyama H,Seki A,Kageyama H,Saito DN,Koeda T,Ohno K,Sadato N

更新日期：2006-12-08 00:00:00

abstract：:The present study reveals developmental changes in the number, the phenotype and the distribution pattern of mast cells (MCs) along the cervical, the thoracic and the lumbar parts of the spinal dura mater. Postnatal infiltration of spinal dura by MCs does not appear to follow a sequential developmental pattern and men...

journal_title：Brain research

authors： Michaloudi H,Batzios C,Chiotelli M,Grivas I,Papadopoulos GC

更新日期：2008-08-21 00:00:00

abstract：:Examination of the projection from area 2 of the sensory cortex to the motor cortex revealed substantial changes following lesion of the ventrolateral nucleus of the thalamus. These observed changes were as follows. (1) The polarity of the evoked potentials elicited by area 2 stimulation reversed in the depth of the m...

journal_title：Brain research

authors： Asanuma H,Kosar E,Tsukahara N,Robinson H

更新日期：1985-10-14 00:00:00

abstract：:The present report summarizes the results obtained in previous experiments in which the responses to lateral tilt of both reticulocerebellar neurons located in the lateral reticular nucleus (NRL) and ascending spinoreticular tract axons, located in the lateral funiculi of the cervical segments C2-C3, had been recorded...

journal_title：Brain research

authors： Pompeiano O

更新日期：1975-09-23 00:00:00

abstract：:We compared the clinical and pharmacodynamic effects of N-terminal methionine brain-derived neurotrophic factor (met-BDNF) and endogenous met-free BDNF in wobbler mouse motor neuron disease (MND). Met- or met-free BDNF at 5 or 20 mg/kg was subcutaneously injected daily, six times/week for 4 weeks. At 20 mg/kg, grip st...

journal_title：Brain research

authors： Ishiyama T,Ogo H,Wong V,Klinkosz B,Noguchi H,Nakayama C,Mitsumoto H

更新日期：2002-07-19 00:00:00

abstract：:Superior colliculus cells that respond to a given sensory input (visual or auditory) were influenced by the presence of a stimulus in the other modality. This is a form of sensory-sensory integration which has previously been thought to be involved in initiating the orientation of receptor organs in response to such c...

journal_title：Brain research

authors： Peck CK

更新日期：1987-09-08 00:00:00

abstract：:Alzheimer's disease (AD) is one of the most common forms of dementia with still unknown pathogenesis. Several cytokines and chemokines are involved in the pathogenesis of AD. Among the chemokines, the CXCR4/CXCL12 complex has been shown to play an important role in the pathogenetic development of AD. We investigated t...

journal_title：Brain research

authors： Sanfilippo C,Castrogiovanni P,Imbesi R,Nunnari G,Di Rosa M

更新日期：2020-12-15 00:00:00

abstract：:While exposure of cultured spinal neurons to mild hypothermia provides some protection from physical trauma (dendrotomy), profound cooling (< 17 degrees C) causes unrelated neuronal injury and death, which can be prevented by treatment with NMDA receptor antagonists. To investigate the mechanism of hypothermic neurona...

journal_title：Brain research

authors： Emery DG,Lucas JH

更新日期：1995-09-18 00:00:00

abstract：:The modulation of tetrodotoxin-sensitive (TTX-S) and slow tetrodotoxin-resistant (TTX-R) sodium currents in rat dorsal root ganglion neurons by ATP was studied using the whole-cell patch-clamp method. The effects of ATP on two types of sodium currents were either stimulatory or inhibitory depending on the kinetic para...

journal_title：Brain research

authors： Joo Choi E,Hong MP,Kyoo Shin Y,Soo Lee C,Park M,Song JH

更新日期：2003-04-04 00:00:00

abstract：:The development of bombesin-like peptides and their receptors was determined in 9 different rat brain regions. The concentration of immunoreactive bombesin increased dramatically in all brain regions examined during the third week after birth. In contrast, the density of [125I-Tyr4]bombesin binding sites was near maxi...

journal_title：Brain research

authors： Gillati MT,Moody TW

更新日期：1984-08-01 00:00:00

abstract：:The functional influence of the cholinergic input to cat dLGN has been examined by assessing the action of iontophoretically applied acetylcholine (ACh) on the visual responses of cells in layers A and A1. Iontophoretically applied pulses of ACh exerted a strong excitatory action on all 113 cells studied within these ...

journal_title：Brain research

authors： Sillito AM,Kemp JA,Berardi N

更新日期：1983-12-05 00:00:00

abstract：:The present study was designed to investigate the existence of two key enzymes involved in the metabolism of gamma-aminobutyric acid, glutamic acid decarboxylase (GAD) and glutamine synthetase (GS), in the area postrema (AP) of the cat. The results showed that punctuate structures of variable size corresponding to axo...

journal_title：Brain research

authors： D'Amelio FE,Mehler WR,Gibbs MA,Eng LF,Wu JY

更新日期：1987-05-05 00:00:00

abstract：:The projection from the vestibular and perihypoglossal nuclei to the spinal trigeminal and lateral reticular nuclei has been studied in cats where the wheat germ agglutinin-horseradish peroxidase complex has been used as a retrograde tracer. All injections were made at the level of the caudal pole of the inferior oliv...

journal_title：Brain research

authors： Walberg F,Dietrichs E,Nordby T

更新日期：1985-04-29 00:00:00

abstract：:Neuromuscular patterns associated with the development of hindlimb stepping behaviors were studied from birth to postnatal day 60 in normal kittens. Hindlimb muscles were chronically implanted with EMG electrodes at birth to characterize interlimb coordination and intralimb synergies during development of overground a...

journal_title：Brain research

authors： Bradley NS,Smith JL

更新日期：1988-01-01 00:00:00

abstract：:Blockade of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors with 6-nitro-7-sulfamoyl-benzo-[f]quinoxaline-2,3(1H,4H)-dione (NBQX) activates tuberoinfundibular (TIDA) and periventricular-hypophysial dopaminergic (PHDA) neurons suggesting that these neurons are tonically inhibited by endogenous...

journal_title：Brain research

authors： Wagner EJ,Moore KE,Lookingland KJ

更新日期：1994-10-17 00:00:00

abstract：:Sleep is posited to be a fundamental property of groups of highly interconnected neurons and regulated in part by activity-dependent sleep regulatory substances such as tumor necrosis factor alpha (TNFalpha). We show that the unilateral local application of TNFalpha onto the somatosensory cortex of rats induced state-...

journal_title：Brain research

authors： Yoshida H,Peterfi Z,García-García F,Kirkpatrick R,Yasuda T,Krueger JM

更新日期：2004-05-29 00:00:00

abstract：:Many of our everyday actions are only appropriate in certain situations and selecting the appropriate behavior requires that we use current context and previous experience to guide our decisions. The current study examined hippocampal functional connectivity with prefrontal and striatal regions during a task that requ...

journal_title：Brain research

authors： Ross RS,Sherrill KR,Stern CE

更新日期：2011-11-14 00:00:00

abstract：:Spinal cord injury (SCI) often results in some form of paralysis. Recently, SCI therapy has been focused on preventing secondary injury to reduce both neuroinflammation and lesion size so that functional outcome after an SCI may be improved. Previous studies have shown that adenosine receptors (AR) are a major regulat...

journal_title：Brain research

authors： Yang CC,Jou IM

更新日期：2016-03-01 00:00:00

abstract：:The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...

journal_title：Brain research

authors： Watanabe Y,Watanabe T,Kitagawa M,Taya Y,Nakayama K,Motoyama N

更新日期：1999-09-25 00:00:00

abstract：:Bradykinin is known to rapidly elevate intracellular calcium leading to secretion of neurotransmitters and short term activation of tyrosine hydroxylase (TH). In this study we examined the effect of bradykinin on mRNA levels of two catecholamine biosynthetic enzymes. Treatment of PC12 cells with 1 microM bradykinin fo...

journal_title：Brain research

authors： Gebreyesus K,Kilbourne EJ,Sabban EL

更新日期：1993-04-16 00:00:00

abstract：:The cholinergic nicotinic agonists (-)nicotine and lobeline were observed to partially inhibit whole-cell N-methyl-D-aspartate (NMDA)-induced responses in rat cortical neurons in culture. In addition we found that (-)nicotine, (+)nicotine, and lobeline, but not the nicotine metabolite (-)cotinine nor acetylcholine, we...

journal_title：Brain research

authors： Aizenman E,Tang LH,Reynolds IJ

更新日期：1991-06-14 00:00:00

abstract：:The rubrointerposital projection was studied in cats where wheat germ agglutinin-horseradish peroxidase (WGA-HRP) was implanted in various parts of the interposed nuclei. No retrogradely labelled rubral cells were observed following implantations in the posterior interposed nucleus, and only very few such cells were i...

journal_title：Brain research

authors： Walberg F,Dietrichs E

更新日期：1986-11-05 00:00:00

abstract：:Intradentate administration of colchicine has been reported to affect the cholinergic muscarinic system in the hippocampus, causing a reduction in quinclidinylbenzilate binding sites and an increase in choline acetyltransferase activity. Since the cholinergic muscarinic system is coupled to the formation of inositolph...

journal_title：Brain research

authors： Tandon P,Harry GJ,Tilson HA

更新日期：1989-01-16 00:00:00

abstract：:Focal electrical stimulation and glutamate microinjection in the nuclei reticularis gigantocellularis (NGC) and gigantocellularis pars alpha (NGC alpha) both inhibit the nociceptive tail-flick (TF) reflex in rats. The present experiments were undertaken to determine the transmitter(s) at the level of the lumbar spinal...

journal_title：Brain research

authors： Zhuo M,Gebhart GF

更新日期：1990-12-03 00:00:00

abstract：:The effects of continuous clonidine infusion (10 micrograms/kg/h for 10 days) and the cessation of this infusion on the circadian body temperature rhythm of the spontaneously hypertensive (SH) rat were examined. This circadian rhythm was blunted significantly during the infusion of clonidine. The fall in body temperat...

journal_title：Brain research

authors： Lewis SJ,Maccarrone C,Jarrott B

更新日期：1986-10-22 00:00:00

abstract：:Rats with hippocampal dialysis probes were treated with DL-fenfluramine (FEN), fluoxetine, or FEN with fluoxetine pre-treatment. FEN (12.5 mg/kg) increased extracellular serotonin (5-HT) from 0.4 +/- 0.04 to 25.2 +/- 4.16 pg/10 microliters. Fluoxetine (10.0 mg/kg) increased extracellular 5-HT levels from 0.4 +/- 0.05 ...

journal_title：Brain research

authors： Sabol KE,Richards JB,Seiden LS

更新日期：1992-07-10 00:00:00

abstract：:Brief applications of high glycine concentrations to hippocampal slices have been shown to produce long-lasting changes in synaptic efficacy. In the present study, we show that glycine application transiently and reversibly increases the amplitude and prolongs the duration of synaptic potentials mediated by N-methyl-D...

journal_title：Brain research

authors： Shahi K,Baudry M

更新日期：1993-11-12 00:00:00

abstract：:We report here that following partial spinal transections in adult lampreys, the fibers of the spinal cords can regenerate and restore some intersegmental coordination to the central pattern generator for locomotion, as tested in the isolated cord preparation. However, the regeneration by this test is not successful i...

journal_title：Brain research

authors： Cohen AH,Baker MT,Dobrov TA

更新日期：1989-09-04 00:00:00