Effects on the growth of damaged ganglion cell axons after peripheral nerve transplantation in adult hamsters.

abstract：:Dorsal temporal pole (dTP) is a cortical region at the rostral end of the superior temporal gyrus that forms part of the ventral auditory object processing pathway. Anatomical connections with frontal and medial temporal areas, as well as a recent single-unit recording study, suggest this area may be an important part...

journal_title：Brain research

authors： Bigelow J,Ng CW,Poremba A

更新日期：2016-06-01 00:00:00

abstract：:The homozygous Brattleboro rat (di/di), displaying a hypothalamic form of diabetes insipidus, synthesizes a vasopressin (VP) precursor with an abnormal C-terminus. The phenotypic expression of coexisting peptides in mutant magnocellular VP cells shows a differential pattern. 7B2 is one of the peptides which is not det...

journal_title：Brain research

authors： Gabreëls BA,Sonnemans MA,Seidah NG,Chrétien M,van Leeuwen FW

更新日期：1992-07-10 00:00:00

abstract：:To facilitate the study of the CaMKIIα function in vivo, a CaMKIIα-GFP transgenic mouse line was generated. Here, our goal is to provide the first neuroanatomical characterization of GFP expression in the CNS of this line of mouse. Overall, CaMKIIα-GFP expression is strong and highly heterogeneous, with the dentate gy...

journal_title：Brain research

authors： Wang X,Zhang C,Szábo G,Sun QQ

更新日期：2013-06-26 00:00:00

abstract：:The formation of reactive oxygen species (ROS) has been suggested to be associated with excitotoxicity but the involvement of cytoplasmic enzymes in ROS formation is not clearly known. In the present study, we examined the role of xanthine oxidase (XO), nitric oxide synthase (NOS) and phospholipase A(2) (PLA(2)) in gl...

journal_title：Brain research

authors： Sanganahalli BG,Joshi PG,Joshi NB

更新日期：2005-03-10 00:00:00

abstract：:Intracisternal (i.c.) administration of the endogenous tridecapeptide neurotensin (NT) has been previously shown to significantly reduce the incidence of cold-restraint stress (CRS)-induced gastric ulcers in rats. In this study we confirm the cytoprotective activity of central NT, and document structure-activity relat...

journal_title：Brain research

authors： Hernandez DE,Richardson CM,Nemeroff CB,Orlando RC,St-Pierre S,Rioux F,Prange AJ Jr

更新日期：1984-05-28 00:00:00

abstract：:The localization of the methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu)-like immunoreactivity-containing neurons in the rat lumbosacral spinal cord was immunohistochemically examined by an antiserum very specific to Met-Enk-Arg-Gly-Leu. The immunoreactive neurons occupied the positions corresponding to the ...

journal_title：Brain research

authors： Shimosegawa T,Koizumi M,Toyota T,Goto Y,Yanaihara C,Yanaihara N

更新日期：1987-03-17 00:00:00

abstract：:The effects of psychological stress on catecholamine and indoleamine metabolism were examined in various brain regions of rats. Psychologically stressed rats were exposed to emotional responses of foot-shocked rats, but were themselves prevented from receiving foot-shock. Psychological stress for 30 min resulted in si...

journal_title：Brain research

authors： Kaneyuki H,Yokoo H,Tsuda A,Yoshida M,Mizuki Y,Yamada M,Tanaka M

更新日期：1991-08-23 00:00:00

abstract：:Intrathecally-administered clonidine inhibited the spontaneous firing of single neurons in the pontine nucleus locus coeruleus of rats. Such inhibition of neuron firing was not observed when the non-lipophilic alpha 2 adrenoceptor agonist (oxymetazoline) was administered intrathecally. It is concluded that lipophilic ...

journal_title：Brain research

authors： Marwaha J,Kehne JH,Commissaris RL,Lakoski J,Shaw W,Davis M

更新日期：1983-10-16 00:00:00

abstract：:Acute swim stress of mice produces increases in the density of high and low affinity binding sites in the brain for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), together with analgesia as measured by an increase in tail flick latency. Apparent tolerance develops in repeated swimming with analgesia a...

journal_title：Brain research

authors： Skerritt JH,Trisdikoon P,Johnston GA

更新日期：1981-06-29 00:00:00

abstract：:The ability of beta-phenylethylamine (PEA) to reverse (1) chlorpromazine-induced activation of striatal tyrosine hydroxylase, and (2) catalepsy produced by chlorpromazine, was examined. PEA, in a dose of 75 mg/kg, caused approximately 50% reduction in the degree of tyrosine hydroxylase stimulation produced by 20 mg/kg...

journal_title：Brain research

authors： Stoff DM,Gale K

更新日期：1981-05-04 00:00:00

abstract：:Responses of subthalamic neurons (STN) to the iontophoretic application of glutamate (Glu), acetylcholine (ACh) and GABA were studied in rats 2 or 3 weeks following bilateral decortication, and were compared to those obtained in normal animals. All the cells recorded in lesioned rats showed a decrease in their spontan...

journal_title：Brain research

authors： Rouzaire-Dubois B,Scarnati E

更新日期：1987-02-17 00:00:00

abstract：:Serotonin (5-HT) participates in pain modulation by interacting with different 5-HT receptors. The role of 5-HT5A receptor in neuropathic pain has not previously studied. The purpose of this study was to investigate: A) the role of 5-HT5A receptors in rats subjected to spinal nerve injury; B) the expression of 5-HT5A ...

journal_title：Brain research

authors： Avila-Rojas SH,Velázquez-Lagunas I,Salinas-Abarca AB,Barragán-Iglesias P,Pineda-Farias JB,Granados-Soto V

更新日期：2015-10-05 00:00:00

abstract：:Recent studies have demonstrated that sensory hair cells in the avian inner ear are reproduced by cell proliferation in response to the death of the original hair cell population. The regenerated hair cells appear to construct functional synaptic contacts, thereby transmitting acoustic signals to the peripheral nervou...

journal_title：Brain research

authors： Hashino E,Salvi RJ

更新日期：1996-05-13 00:00:00

abstract：:Choline uptake and ecto-cholinesterase activities have been measured in intact astroblast and neuroblast cultures. The data show that choline uptake is dependent upon the ionic composition of the culture medium and is sensitive to metabolic inhibitors. However, the high concentrations of the inhibitors necessary for t...

journal_title：Brain research

authors： Massarelli R,Stefanovic V,Mandel P

更新日期：1976-08-06 00:00:00

abstract：:We have examined the influence of reducing conditions on the activity of group-I or -II metabotropic glutamate receptors. In cultured cerebellar granule cells or in hippocampal slices, the reducing agent dithiothreitol (DTT) inhibited the stimulation of polyphosphoinositide (PPI) hydrolysis elicited by group-I mGlu re...

journal_title：Brain research

authors： Copani A,Romano C,Di Giorgi Gerevini V,Nicosia A,Casabona G,Storto M,Mutel V,Nicoletti F

更新日期：2000-06-09 00:00:00

abstract：:Opiate regulation of the nuclear proto-oncogene c-fos was studied in the locus coeruleus (LC) and other regions of rat brain by immunoblotting, northern blotting, and in situ hybridization procedures. Precipitation of opiate withdrawal in rats, which is known to increase LC firing rates 4-fold, led to a two- to three-...

journal_title：Brain research

authors： Hayward MD,Duman RS,Nestler EJ

更新日期：1990-08-20 00:00:00

abstract：:We have previously shown that the HSV-2 anti-apoptotic protein ICP10PK is delivered by the replication incompetent virus mutant DeltaRR and prevents kainic acid (KA)-induced epileptiform seizures and neuronal cell loss in the mouse and rat models of temporal lobe epilepsy. The present studies used DeltaRR and the ICP1...

journal_title：Brain research

authors： Gober MD,Laing JM,Thompson SM,Aurelian L

更新日期：2006-11-13 00:00:00

abstract：:Three types of hyperpolarization in response to applied acetylcholine (ACh) were observed in 4 identified neurones (RP1, RP2, RP3 and RP4) in the right parietal ganglion of the African giant snail, Achatina fulica Férussac. In order to clarify the ionic mechanisms of these responses, the neurones were voltage-clamped ...

journal_title：Brain research

authors： Furukawa Y,Kobayashi M

更新日期：1986-05-28 00:00:00

abstract：:The present study evaluated whether environmental enrichment-related effects on the development of stereotyped behavior in deer mice were associated with alterations in neuronal metabolic activity. Deer mice were reared under either enriched or standard housing conditions for 60 days following weaning. All mice were t...

journal_title：Brain research

authors： Turner CA,Yang MC,Lewis MH

更新日期：2002-05-31 00:00:00

abstract：:Neuropathic pain remains a major complication of various forms of injury to peripheral nerves in humans. Recently, 2 models of peripheral mononeuropathy in the rat have been described which closely resemble the human condition. Bennett and Xie3 described one model induced by the placement of 4 loose ligatures around t...

journal_title：Brain research

authors： Dougherty PM,Garrison CJ,Carlton SM

更新日期：1992-01-20 00:00:00

abstract：:Recent studies suggest that both sex and cerebral hemisphere influence brain mechanisms associated with emotional memory. Here we used evoked potentials to examine the influence of sex and hemisphere on brain responses to emotional stimuli. Given that the P300 component of the event-related brain potential (ERP) is co...

journal_title：Brain research

authors： Gasbarri A,Arnone B,Pompili A,Pacitti F,Pacitti C,Cahill L

更新日期：2007-03-23 00:00:00

abstract：:The localization of calcitonin gene-related peptide (CGRP)-like immunoreactive (CGRPI) structures in the cochlea was examined in the rat using immunocytochemistry. Numerous CGRPI fibers entered the organ of Corti in the intraganglionic spiral bundle and formed a dense fiber patch at the base of the inner hair cells. M...

journal_title：Brain research

authors： Kitajiri M,Yamashita T,Tohyama Y,Kumazawa T,Takeda N,Kawasaki Y,Matsunaga T,Girgis S,Hillyard CJ,MacIntyre I

更新日期：1985-12-09 00:00:00

abstract：:Effects of ketamine on glutamate-induced swelling of astrocytes in primary cell culture were studied. Following the exposure to 1 mM glutamate (Glu) for 4 h the intracellular water space (as measured by 3-O-methyl-[14C]glucose uptake) of astrocytes was increased by two-fold concomitant with cell swelling and disappear...

journal_title：Brain research

authors： Chan PH,Chu L

更新日期：1989-05-22 00:00:00

abstract：OBJECTIVE:Our asphyxia cardiac arrest (ACA) rat model is well established. The original model was designed in the 1990th using halothane and nitrous oxide for pre-insult anesthesia. Because of its hepato-toxicity and its potential to induce severe liver failures, halothane is no longer used in clinical anesthesia for s...

journal_title：Brain research

authors： Esser T,Keilhoff G,Ebmeyer U

更新日期：2016-12-01 00:00:00

abstract：:Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system. We have investigated the effects of NT incubation with rat neostriatal slices on calcium/calmodulin (Ca/CaM)-dependent protein phosphorylation. Slices were incubated with NT (5 or 50 nM) fo...

journal_title：Brain research

authors： Kasckow J,Cain ST,Nemeroff CB

更新日期：1991-04-05 00:00:00

abstract：:The respiratory role of GABA(A), GABA(B) and glycine receptors within the Bötzinger complex (BötC) and the pre-Bötzinger complex (preBötC) was investigated in alpha-chloralose-urethane anesthetized, vagotomized, paralysed and artificially ventilated rabbits by using bilateral microinjections (30-50 nl) of GABA and gly...

journal_title：Brain research

authors： Bongianni F,Mutolo D,Cinelli E,Pantaleo T

更新日期：2010-07-16 00:00:00

abstract：:Intracellular recordings were obtained from CA1 pyramidal neurons in obliquely cut in vitro hippocampal slices. Recurrent IPSPs were elicited by antidromic stimulation of alvear fibers. The mechanisms by which IPSPs depress pyramidal cell excitability were investigated. Recurrent IPSPs could be reversed in sign by sma...

journal_title：Brain research

authors： Dingledine R,Langmoen IA

更新日期：1980-03-10 00:00:00

abstract：:Motoneuron phenotype in the spinal cord is regulated by an intrinsic genetic program, extrinsic environmental signals and target-derived molecules. Axonal lesions trigger a phenotype switch to foster repair phenomena and axonal re-growth. We have investigated the influence of the long-term treatment with thyroid hormo...

journal_title：Brain research

authors： Giardino L,Giuliani A,Bettelli C,Calzà L

更新日期：2002-01-25 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is characterized by a progressive degeneration of upper and lower motor neurons, resulting in fatal paralysis due to denervation of the muscle. Due to genetic, pathological and symptomatic overlap, ALS is now considered a spectrum disease together with frontotemporal dementia (FTD),...

journal_title：Brain research

authors： Starr A,Sattler R

更新日期：2018-08-15 00:00:00

abstract：:Antagonism of NMDA-mediated transmission by MK-801 has been shown to block long-term potentiation (LTP) in vitro and delay electrical kindling of the amygdala. The present experiment sought to examine the relationship between synaptic potentiation of the perforant path-granule cell synapse and development of perforant...

journal_title：Brain research

authors： Gilbert ME,Mack CM

更新日期：1990-06-11 00:00:00