Fluoxetine attenuates the DL-fenfluramine-induced increase in extracellular serotonin as measured by in vivo dialysis.

abstract：:To elucidate the anatomical distribution of the serotonergic neurotransmitter system, we identified serotonin transporter (5-HTT) in the hippocampus of rats and monkeys by immunohistochemistry. A widespread and heterogeneous distribution of 5-HTT-immunoreactive fine fibers was noted in the rat brain. However, in monke...

journal_title：Brain research

authors： Owashi T,Iritani S,Niizato K,Ikeda K,Kamijima K

更新日期：2004-06-04 00:00:00

abstract：:alpha-Motoneurons innervating the triceps surae and short plantar muscles were stained intracellularly with horseradish peroxidase (HRP) in 0-44-day-old kittens and adult cats. The terminal arborizations of the recurrent axon collaterals in the spinal cord were studied in the light microscope (LM). The short plantar m...

journal_title：Brain research

authors： Cullheim S,Ulfhak B

更新日期：1985-01-01 00:00:00

abstract：:Cultures of neonatal mouse cortical astrocytes synthesized NGF mRNA and released immunoreactive NGF (ir-NGF) into the culture medium. Addition of 10 microM guanosine or GTP to the cultures increased ir-NGF release by 6 and 2 fold, respectively, after 24 h, and increased NGF mRNA 6 fold after 4 h and 2-3 fold after 24 ...

journal_title：Brain research

authors： Middlemiss PJ,Gysbers JW,Rathbone MP

更新日期：1995-04-17 00:00:00

abstract：:Extracellular recordings were carried out in the primary visual cortex of behaving macaque monkeys. Neurons were activated by moving a visual stimulus across their receptive fields during periods of steady fixation and by moving their receptive fields (by visual tracking) across a motionless visual stimulus, taking ca...

journal_title：Brain research

authors： Galletti C,Squatrito S,Battaglini PP,Grazia Maioli M

更新日期：1984-05-28 00:00:00

abstract：:We observed chronological changes of platelet endothelial cell adhesion molecule-1 (PECAM-1), final mediator of neutrophil transendothelial migration, immunoreactivity, and protein level in the gerbil hippocampus proper after 5 min of transient ischemia. One day after ischemic insult, PECAM-1 immunoreactivity and prot...

journal_title：Brain research

authors： Hwang IK,Kim DW,Yoo KY,Jung BK,Song JH,Jung JY,Choi SY,Kang TC,Lee JY,Kwon YG,Won MH

更新日期：2005-06-28 00:00:00

abstract：:Many of our everyday actions are only appropriate in certain situations and selecting the appropriate behavior requires that we use current context and previous experience to guide our decisions. The current study examined hippocampal functional connectivity with prefrontal and striatal regions during a task that requ...

journal_title：Brain research

authors： Ross RS,Sherrill KR,Stern CE

更新日期：2011-11-14 00:00:00

abstract：:There is no sex difference in the number of axodendritic synapses in the lateral septum of adult rats. However, the treatment of adult females with estradiol (E2) for 4 weeks increases significantly the number of synapses, whereas E2 treatment fails to increase the synaptic number in males, suggesting a possible sexua...

journal_title：Brain research

authors： Miyakawa M,Arai Y

更新日期：1987-12-08 00:00:00

abstract：:Several neurologic illnesses in which excitotoxic mechanisms may play a role increase in prevalence with age. In the present study we examined the susceptibility of rats to quinolinic acid striatal lesions at 1, 4 and 20 months of age, and susceptibility to N-methyl-D-aspartate (NMDA) at 1 and 4 months of age. The ext...

journal_title：Brain research

authors： Finn SF,Hyman BT,Storey E,Miller JM,Beal MF

更新日期：1991-10-25 00:00:00

abstract：:Transient global cerebral ischemia has been shown to induce marked changes in the polyamine pathway with a significant increase in putrescine, the product of the ornithine decarboxylase reaction. This study examined the relationship between tissue and extracellular polyamines and regional cerebral blood flow and brain...

journal_title：Brain research

authors： Başkaya MK,Rao AM,Dogan A,Donaldson D,Gellin G,Dempsey RJ

更新日期：1997-01-09 00:00:00

abstract：:Mechanical hyperalgesia is an early symptom of diabetic neuropathy. To evaluate the mechanisms underlying this symptom, it was studied and compared in rat models of systemic and local hyperglycemia. Systemic hyperglycemia was induced by a single injection of streptozotocin (STZ, 50 mg/kg). Local hyperglycemia either i...

journal_title：Brain research

authors： Dobretsov M,Hastings SL,Romanovsky D,Stimers JR,Zhang JM

更新日期：2003-01-17 00:00:00

abstract：:Brainstem noradrenergic neurons located in the A5, A6, and A7 catecholamine cell groups provide the entire noradrenergic innervation of the spinal cord. We have previously demonstrated that noradrenergic neurons in the A6 and A7 cell groups innervate the ventral and dorsal horns, respectively. Since the specific spina...

journal_title：Brain research

authors： Clark FM,Proudfit HK

更新日期：1993-07-09 00:00:00

abstract：:Male rats were treated with 10 mg/kg D-fenfluramine (DF) i.p., twice a day for 4 days. Five days later there was a strong reduction (70-100%) in the Bmax of [3H]citalopram binding and the Vmax of [3H]5-HT uptake in cortical and hippocampal synaptosomes; 2 months after the treatment these parameters were reduced by 40-...

journal_title：Brain research

authors： Gobbi M,Mancini L,Presti ML,Mennini T

更新日期：1996-08-19 00:00:00

abstract：:The phenomenon whereby the relative timing between presynaptic and postsynaptic spiking determines the direction and extent of synaptic changes in a critical temporal window is known as spike timing-dependent synaptic plasticity (STDP). We have previously reported that STDP profiles can be classified into two types de...

journal_title：Brain research

authors： Kondo M,Kitajima T,Fujii S,Tsukada M,Aihara T

更新日期：2013-08-14 00:00:00

abstract：:The link between the immunolocalization of apolipoproteins E (apo E) and J (apo J) and the different severity of beta-amyloid deposition in various areas of Alzheimer's disease (AD) and Down's syndrome (DS) brain was analyzed. Both apolipoproteins were found in all types of senile plaques (SPs) in the cerebral cortex,...

journal_title：Brain research

authors： Kida E,Choi-Miura NH,Wisniewski KE

更新日期：1995-07-10 00:00:00

abstract：:Rab3A is a small GTP-binding synaptic vesicle protein, shown to dissociate from synaptic vesicle membranes upon depolarization-induced exocytosis. Using an antiserum raised against rab3A, we found that the antigen was localized to the neuropil of specific brain regions, but was not present in major fiber tracts or mos...

journal_title：Brain research

authors： Moya KL,Tavitian B,Zahraoui A,Tavitian A

更新日期：1992-09-11 00:00:00

abstract：:In auditory speech processing, phonological stress functions as an attention holding cue, which facilitates detection of mispronunciations and phonetic deviants in strong syllables as compared to weak ones. Whereas silent reading involves activation of phonological information including word stress, it is not clear wh...

journal_title：Brain research

authors： Kriukova O,Mani N

更新日期：2016-04-01 00:00:00

abstract：:Cardiovascular responses to electrical microstimulation of the ventrolateral medulla were investigated in both Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) under pentobarbital anesthesia. The threshold intensity required to elicit a change in blood pressure (BP) and the cardiovascular responses in...

journal_title：Brain research

authors： Chan RK,Chan YS,Wong TM

更新日期：1990-07-02 00:00:00

abstract：:Depolarizing actions of 4 conformationally restricted L-glutamate analogues, (2S,3S,4S) isomer (L-CCG-I), (2S,3R,4R) isomer (L-CCG-II), (2S,3S,4R) isomer (L-CCG-III) and (2S,3R,4S) isomer (L-CCG-IV) of L-alpha-(carboxycyclopropyl)-glycine (L-CCG), were investigated in the isolated rat spinal cord by extracellular reco...

journal_title：Brain research

authors： Shinozaki H,Ishida M,Shimamoto K,Ohfune Y

更新日期：1989-02-20 00:00:00

abstract：:Glucocorticoids (GCs) predispose hippocampal neurons to damage during metabolic stressors. One component of hippocampal GC-endangerment may be changes in neuronal defenses against oxidative challenge. Previous experiments showed a decrease in basal levels of copper/zinc superoxide dismutase (Cu/Zn SOD) and glutathione...

journal_title：Brain research

authors： McIntosh LJ,Cortopassi KM,Sapolsky RM

更新日期：1998-04-27 00:00:00

abstract：:The effects of intracerebroventricular (i.c.v.) infusion of arginine vasopressin (AVP) on intracranial pressure (ICP), blood pressure (BP) and plasma AVP were investigated in conscious goats. The animals were implanted with ventricular (V) and cisternal (C) cannulae under halothane anaesthesia and allowed to recover p...

journal_title：Brain research

authors： Seckl JR,Lightman SL

更新日期：1987-10-13 00:00:00

abstract：:Two distinct serotonin receptors in mammalian brain are labeled respectively with [3H]serotonin (5-HT1) and [3H]spiperone (5-HT2). In general agonists display highest affinities for 5-HT1 while antagonists prefer 5-HT2 sites. To conduct regional studies of 5-HT receptors, we estimated 5-HT2 sites with [3H]spiperone, u...

journal_title：Brain research

authors： Peroutka SJ,Snyder SH

更新日期：1981-03-16 00:00:00

abstract：:Averaged evoked potentials and unitary discharges in response to tooth pulp and acoustic click stimuli were recorded from the hippocampus of freely moving rats. The spatial distribution of evoked field responses to tooth pulp stimulation and acoustic clicks were identical. Averaged evoked potentials consisted of a lar...

journal_title：Brain research

authors： Brankack J,Buzsáki G

更新日期：1986-07-23 00:00:00

abstract：:The effect of hippocampal kindling on neuronal and glial marker proteins was studied in the rat by immunochemical methods. In hippocampus, pyriform cortex and amygdala there was an increase in glial fibrillary acidic protein (GFAP), indicating reactive gliosis, and an increase in the glycolytic enzyme NSE, suggesting ...

journal_title：Brain research

authors： Hansen A,Jørgensen OS,Bolwig TG,Barry DI

更新日期：1990-10-29 00:00:00

abstract：:The response of granule cells and CA1 pyramidal neurones to NMDA was studied in the presence and absence of Mg2+ using an in vitro slice preparation. In the absence of Mg2+ the depolarizing response of hippocampal neurones to NMDA is accompanied by a decrease in input resistance. In the presence of Mg2+ ions, however,...

journal_title：Brain research

authors： Crunelli V,Mayer ML

更新日期：1984-10-08 00:00:00

abstract：:Endogenous gamma-aminobutyric acid (GABA) release from the rat medial preoptic area (MPOA) was measured in an in vitro slice technique with sensitive HPLC analysis. Oestrogen is demonstrated to increase GABA activity in the ovariectomised, oestrogen-primed (OVX-EB) rat prior to the luteinising hormone (LH) surge compa...

journal_title：Brain research

authors： Herbison AE,Heavens RP,Dyer RG

更新日期：1989-05-01 00:00:00

abstract：:Ligation of CD27, a member of the tumor necrosis factor (TNF) receptor family, by its ligand CD70 is thought to be important in T cell activation, expansion and survival, B cell activation, and NK cell activation. We examined the role of CD70 in Theiler's murine encephalomyelitis virus-induced demyelinating disease (T...

journal_title：Brain research

authors： Yanagisawa S,Takeichi N,Kaneyama T,Yagita H,Taniguchi S,Kim BS,Koh CS

更新日期：2010-03-04 00:00:00

abstract：UNLABELLED:Although corticotropin-releasing factor (CRF) receptors have been identified throughout the brain, relatively little is known about the regulation of CRF receptors. Recent investigations aimed at developing an in vitro model for studying the regulation of CRF receptors demonstrated CRF binding in brain cell ...

journal_title：Brain research

authors： Kapcala LP,De Souza EB

更新日期：1988-07-19 00:00:00

abstract：:Convulsions were induced in young rats (1-21 days) with pentylenetetrazol or hyperthermia. As adults, these animals were kindled electrically in the basolateral or cortical amygdala, the hippocampus, or the pyriform cortex. Fewer amygdala stimulations were required to evoke major motor seizures in subjects treated at ...

journal_title：Brain research

authors： Gilbert ME,Cain DP

更新日期：1985-10-01 00:00:00

abstract：:The innervation of the tensor tympani muscle of the middle ear in Macaca fascicularis (cynomolgus monkey) was studied using the horseradish peroxidase (HRP) neural tracing technique. A compact column of small trigeminal motoneurons was labeled ipsilaterally following intramuscular application of HRP to the tensor tymp...

journal_title：Brain research

authors： Gannon PJ,Eden AR

更新日期：1987-02-24 00:00:00

abstract：:Pain resulting from peripheral nerve injury, characterised by ongoing pain, hyperalgesia and allodynia arises from peripheral and central processes. Here, we studied the potential role of central facilitations in nerve injury by investigating the effect of blocking the excitatory 5HT3 receptor with ondansetron. 5HT3 r...

journal_title：Brain research

authors： Suzuki R,Rahman W,Hunt SP,Dickenson AH

更新日期：2004-09-03 00:00:00