Abstract:
:The present report summarizes the results obtained in previous experiments in which the responses to lateral tilt of both reticulocerebellar neurons located in the lateral reticular nucleus (NRL) and ascending spinoreticular tract axons, located in the lateral funiculi of the cervical segments C2-C3, had been recorded in precollicular decerebrate cats. Steady changes in unit activity were evoked by 15-20 degrees tilts which lasted as long as the position of the cat was maintained. Most of the units responsive to tilting showed an increase in discharge rate during tilt in one direction and a decrease in discharge rate during tilt in the opposite direction. Moreover the magnitude of the unitary responses was clearly related to the degree of tilt. The responses of the NRL neurons to tilt were attributed in part to direct efferent vestibuloreticular projections from the Deiters' nucleus, in part to some indirect influence of the lateral vestibulospinal tract on neurons of the cervical ascending spinoreticular pathway. Since most of these ascending units affected by tilt were influenced by stimulation of both ipsilateral and contralateral forelimb nerves, and some of them also by stimulation of high threshold neck muscle afferents, it was postulated that these neurons projected to the forelimb and the neck region of the cerebellar cortex of the anterior lobe. This corticocerebellar region may therefore integrate from time to time not only the signal input originating from macular receptors but also the somatosensory input which originates from neck receptors as a result of the actual displacement in head position induced by the vestibulospinal reflex.
journal_name
Brain Resjournal_title
Brain researchauthors
Pompeiano Odoi
10.1016/0006-8993(75)90112-2subject
Has Abstractpub_date
1975-09-23 00:00:00pages
351-68issue
2-3eissn
0006-8993issn
1872-6240pii
0006-8993(75)90112-2journal_volume
95pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Variations in cerebral blood flow and partial pressures of oxygen and carbon dioxide (pO2, pCO2) were studied in rabbits during short-duration (1 min) immobilization stress. The techniques used enabled us to determine these variables locally in the caudate nucleus in a continuous, simultaneous and quantitative fashion...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90927-8
更新日期:1985-08-12 00:00:00
abstract::Characteristics of neural corticosteroid receptors were studied in 51 adrenally-intact macaque monkeys using a modification of a corticosteroid receptor assay developed in this laboratory for rodent studies. Using cortisol as a ligand, two receptor subtypes could be distinguished and with similar Kd's to those observe...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91249-1
更新日期:1994-02-21 00:00:00
abstract::The phenomenon of unidirectional non-cross tolerance (UNCT) to etorphine was observed in adult male rats tolerant to morphine. Using a morphine pellet (four 75 mg morphine pellets) implantation protocol, a 10-fold increase in the analgesic ED50 value, obtained by tail-flick assay, was observed for morphine sulfate, wi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91502-1
更新日期:1985-02-18 00:00:00
abstract::We have previously observed that chronic cocaine administration increases levels of adenylyl cyclase and cAMP-dependent protein kinase (PKA) in the nucleus accumbens (NAc). In the present work we directly examined the involvement of the cAMP system at the level of the NAc in cocaine-induced locomotor activity and sens...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00030-t
更新日期:1995-03-20 00:00:00
abstract::In the present investigation, electron probe X-ray microanalysis was used to characterize the effects of in vitro ouabain (2 mM) or anoxia on elemental composition (e.g. Na, K, Ca) and water content of rat peripheral (tibial) nerve myelinated axons and Schwann cells. Results showed that independent of axon size, both ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00855-k
更新日期:1995-10-02 00:00:00
abstract::Opiates modulate pain perception at a number of different levels within the central nervous system and the importance of synergistic spinal and supraspinal influences have been well documented. In the present study we demonstrate synergistic interactions between the periaqueductal gray and locus coeruleus. Administere...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90772-n
更新日期:1991-09-06 00:00:00
abstract::The autoradiographic [14C]2-deoxyglucose (2-DG) method was used to map ascending pathways which are influenced by arousing electrical stimulation of the midbrain reticular formation (RET) in alert rats. The major finding was that RET stimulation produces selective patterns of metabolic activation and suppression in di...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91190-4
更新日期:1985-09-30 00:00:00
abstract::A monoclonal antibody was made using the spleen cells of a mouse immunized with chick synaptic membranes and designated as mAb 1D12. It immunoprecipitated 25% of the omega-conotoxin binding protein but no dihydropyridine binding protein solubilized from chick brain membranes. By immunoblotting, a polypeptide of 58-kDa...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90942-o
更新日期:1991-06-14 00:00:00
abstract::Wayfinding is a complex cognitive function involving different types of information, such as knowledge about landmarks and direction information. This variety of processes suggest that multiple neural mechanisms are involved, e.g., the hippocampal system, the posterior parietal and temporal cortical areas. Although pa...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.10.048
更新日期:2006-01-05 00:00:00
abstract::The vascular changes in the hippocampus and neocortex during kainic acid-induced seizures were investigated in control rats and in rats with chronic, bilateral, cervical sympathectomy. Seizures were induced in unanesthetized, spontaneously breathing rats. The increase in blood flow in the hippocampus of the sympathect...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91782-c
更新日期:1990-11-05 00:00:00
abstract::The regional distribution of proline biosynthetic enzymes, ornithine-delta-aminotransferase and delta 1-pyrroline-5-carboxylate reductase, in the rat brain, and basic conditions for proline synthesis from ornithine in rat and chicken brain slices and chicken retinas were investigated. The cerebral regions relating to ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91022-5
更新日期:1987-06-16 00:00:00
abstract::Choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) activities were measured in various visual structures of the pigeon brain after long-term monocular deprivation followed by short-term binocular presence or absence of light stimulation. The short-term phase (45 min) was coupled with a 2-deoxygluco...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)91253-7
更新日期:1982-09-16 00:00:00
abstract::Evidence is presented which suggests that central neural changes occur during the brief early phase after subcutaneous formalin injection that are essential for the expression of pain during the long-lasting (tonic) later phase. First, tonic pain responses to subcutaneous formalin injections are abolished only if the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91835-5
更新日期:1990-12-03 00:00:00
abstract::The spatial and temporal pattern of expression of the protein products of immediate early genes (IEGs) c-fos, fos B, and egr-1 were mapped in medial preoptic area (MPOA) and ventral bed nucleus of stria terminalis (VBST) during maternal behavior in rats. Immunocytochemical analysis indicated significant increases in t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00257-1
更新日期:1998-05-11 00:00:00
abstract::Multiple-unit activity (MUA) in the agranular medial prefrontal cortex (PFC) was recorded in conscious rabbits during a classical conditioning procedure involving repeated pairings of a 4-s tone conditioned stimulus (CS) with eye shock. Prior to behavioral training, significant tone-evoked increases in prefrontal MUA ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91435-7
更新日期:1988-02-23 00:00:00
abstract::Previous studies have shown that one of the genetic variants BDNF val66met polymorphism is associated with drug addiction. Age at onset for drugs abuse has also been regularly cited as a factor associated with high genetic predispositions. We conducted an exploratory research to investigate the association of BDNF val...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.07.022
更新日期:2010-09-24 00:00:00
abstract::Type 1 cannabinoid (CB1) receptors are expressed in high concentrations in the central nervous system, including the basal ganglia, and could have direct or indirect effects on motor behavior through modulation of dopaminergic, glutamatergic and GABA-ergic neurotransmission. Using the CB1 receptor radioligand [(18)F]M...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.12.026
更新日期:2010-02-26 00:00:00
abstract::Studies with radioactive antipyrene and deoxyglucose indicated that both blood flow and metabolism are enhanced in the goldfish optic tectum following a brief visual stimulation. It is concluded that the brain of cold-blooded animals demonstrates regionally regulated physiological alterations, previously reported only...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90195-1
更新日期:1979-01-26 00:00:00
abstract::The possibility that central adenosine A1 and A2a receptors mediate opiate dependence was examined in morphine-treated mice using radioligand binding methods. Mice treated with morphine for 72 h demonstrated significant increases in naloxone precipitated abstinence behaviors of jumping, wet-dog shakes, teeth chatterin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90990-3
更新日期:1994-09-19 00:00:00
abstract::The neocortex has proven resistant to LTP induction using standard in vitro and acute, in vivo preparations. Because the neocortex is widely thought to be involved in long-term information storage, this resistance raises questions about the validity of LTP as a memory model. Recently, we have shown that the neocortex ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02720-7
更新日期:2000-10-20 00:00:00
abstract::This study evaluated the effect of stress during puberty on sexual motivation and the correlation between serum testosterone levels (T) and the absolute power of the theta electroencephalographic rhythms, recorded in the medial prefrontal cortex (mPFC) and basolateral amygdala (BLA) of adult male rats. Thirty males of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2020.146937
更新日期:2020-10-15 00:00:00
abstract::Post traumatic stress disorder (PTSD) is characterised by hyperarousal, anxiety and amnesic symptoms. Deficits in explicit memory recall have been causally related to volume reductions of the hippocampus and prefrontal cortex. While stress-related glucocorticoid secretion appears involved in this apparent atrophy, the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)03033-6
更新日期:2003-09-05 00:00:00
abstract::In this study, we measured regional brain blood flow (BF) in rats during hypoxic exposure. Our data show the hypoxia-induced brain blood flow increase returned to baseline within 1 week as blood hemoglobin increased. Because this return to baseline occurred before capillary angiogenesis, this result suggests that the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.08.046
更新日期:2004-11-19 00:00:00
abstract::The patch clamp technique has been used to study ion channel activity in the apical (ventricular) membrane of epithelial cells from the rat choroid plexus. Two different classes of Cl(-)-selective channel were identified. A low conductance (26 pS) channel which was the predominant feature in cell-attached and inside-o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90988-l
更新日期:1992-09-18 00:00:00
abstract::Hydrocephalus with aqueduct stenosis was a consistent feature in mice which received a single intraperitoneal injection of 6-aminonicotinamide (6-AN) on day 5 postnatal. Chronological investigation revealed that 6-AN-treated mice had aqueductal obstruction with edematously swollen ependymal cells and spongy changes in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(85)90180-4
更新日期:1985-10-01 00:00:00
abstract::The effect of aminoguanidine (AG) on structural abnormalities in optic nerve fibers was evaluated in streptozotocin-induced diabetic rats. Morphometry of myelinated optic nerve fibers showed a partial amelioration on the reduction of the axon size but complete preservation of myelin size with low dose (25 mg kg-1 body...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00512-5
更新日期:1998-08-03 00:00:00
abstract::One model useful for demonstrating axonal regeneration in the central nervous system is that in which peripheral tissue, particularly the iris, is implanted into the brain or spinal cord. The aim of the present study was to establish the origin of some of the regenerating fibers by the use of an autoradiograhic tracin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91121-x
更新日期:1980-09-22 00:00:00
abstract::Neurons immunoreactive for the calcium-binding protein calretinin (CR) were visualized in the substantia nigra (SN) pars compacta (SNc), reticulata (SNr) and lateralis (SNl), the ventral tegmental area (VTA) and the subthalamic nucleus (STN) of squirrel monkeys. The density of CR perikarya was high in VTA, moderate in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01374-1
更新日期:1996-02-05 00:00:00
abstract::The aim of the present study was to investigate the effects of ischemic preconditioning on infarct volume in a rat model of subdural hematoma (SDH). Ischemic preconditioning was induced by 15 min transient middle cerebral artery (MCA) occlusion followed 3 days later by the injection of 300 microl of autologous venous ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)03406-0
更新日期:2002-03-15 00:00:00
abstract::Increased and sustained central delivery of L-dihydroxyphenylalanine (L-DOPA) is a desirable therapeutic strategy in Parkinson's disease. We investigated the effects of peripheral catechol-O-methyltransferase (COMT) inhibition, by the non-toxic drug nitecapone on the metabolism of 6-[18F]fluoro-L-dihydroxyphenylalanin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90556-3
更新日期:1993-10-29 00:00:00