Visual stimulation increases regional cerebral blood flow and metabolism in the goldfish.

abstract：:Prostaglandin E2 (PGE2) is a lipid mediator which plays a role in the generation of inflammatory and neuropathic pain. In the peripheral nervous system, PGE2 sensitizes nociceptive afferent neurons through E-prostanoid (EP) receptors. In the central nervous system, PGE2 modulates pain sensitivity and contributes to th...

journal_title：Brain research

authors： Kanda H,Kobayashi K,Yamanaka H,Okubo M,Dai Y,Noguchi K

更新日期：2021-01-01 00:00:00

abstract：:Malignant stroke-prone spontaneously hypertensive rats (M-SHRSP) develop hypertension and stroke at earlier ages than do nonmalignant SHRSP. Our previous findings suggested that reactive oxygen species were involved in the development of stroke in this strain. Nitric oxide (NO) which is more released at ischemia, migh...

journal_title：Brain research

authors： Tabuchi M,Umegaki K,Ito T,Suzuki M,Tomita I,Ikeda M,Tomita T

更新日期：2002-09-13 00:00:00

abstract：:The distinction between neural mechanisms of explicit and implicit expressions of memory has been well studied at the retrieval stage, but less at encoding. In addition, dissociations obtained in many studies are complicated by methodological difficulties in obtaining process-pure measures of different types of memory...

journal_title：Brain research

authors： Meng Y,Ye X,Gonsalves BD

更新日期：2014-10-17 00:00:00

abstract：BACKGROUND:Metabolites involved in one-carbon metabolism (OCM) may predict cognitive prognosis in dementia. The link between OCM, apolipoprotein E (APOE), and DNA methylation creates a biologically plausible mechanism of interaction. AIM:To assess OCM metabolites as predictors of 5-year cognitive prognosis in patients...

journal_title：Brain research

authors： Hildre AS,Solvang SH,Aarsland D,Midtun Ø,McCann A,Ervik AO,Nygård O,Ueland PM,Nordrehaug JE,Giil LM

更新日期：2020-01-01 00:00:00

abstract：:The electrophysiological characteristics of physiologically typed L7 and S1 dorsal root ganglion (DRG) cells have been studied in the cat by intracellular recording. The injection of the fluorescent dye Lucifer Yellow has enabled us to study the morphology of these neurons. Our results show that over the entire range ...

journal_title：Brain research

authors： Cameron AA,Leah JD,Snow PJ

更新日期：1986-01-01 00:00:00

abstract：:Many parts of the brainstem are known to be innervated by the cholinergic neurons of the pontomesencephalic tegmentum, but other possible sources of this innervation have rarely been considered. We sought to examine whether other cells in the brainstem were responsible for this cholinergic input using axonal tract tra...

journal_title：Brain research

authors： Sherriff FE,Henderson Z

更新日期：1994-02-04 00:00:00

abstract：:Pars interpolaris of the spinal trigeminal nucleus of kittens has been studied with the electron microscope at birth and at several subsequent ages during the first month of life. Attention has been given to ultrastructural maturational changes that occur in this neuropil, especially events in synaptogenesis. The resu...

journal_title：Brain research

authors： Dunn RC,Westrum LE

更新日期：1978-03-31 00:00:00

abstract：:Alterations occurring in the antioxidant enzymes, copper, zinc-dependent superoxide dismutase (Cu,Zn-SOD) and glutathione peroxidase (GPX) following nigral dopaminergic denervation are unclear. We now report on the distribution and levels of m-RNA for Cu,Zn-SOD and GPX in basal ganglia of normal and 1-methyl-4-phenyl-...

journal_title：Brain research

authors： Kunikowska G,Jenner P

更新日期：2003-04-11 00:00:00

abstract：:The lamination of the hippocampus in the homozygous B6CBA weaver mouse (wv/wv) was compared with that in normal B6CBA littermates (+/+) and C57BL/6J mice using Nissl and Timm's staining. In Nissl-stained preparations, the normal littermates exhibit a compact, regular arrangement of pyramidal cells in area CA3 of the h...

journal_title：Brain research

authors： Sekiguchi M,Nowakowski RS,Nagato Y,Tanaka O,Guo H,Madoka M,Abe H

更新日期：1995-10-23 00:00:00

abstract：:Immunohistochemistry for Kv1.2, a subunit of voltage-gated K(+) channels, was performed on the trigeminal ganglion (TG). Immunoreactivity (ir) was detected in half (48%) the TG neurons. These neurons were mostly medium-sized to large (range 137.6-2664.8 microm(2), mean+/-S.D. 892.6+/-413.3 microm(2)). A double immunof...

journal_title：Brain research

authors： Ichikawa H,Sugimoto T

更新日期：2003-06-06 00:00:00

abstract：:The Leu-enkephalin dalargin does not normally penetrate the blood brain barrier when given intravenously. Drug targeting to the brain was investigated by using poly(butylcyanoacrylate) nanoparticles which were coated with polysorbate 80. When injected intravenously in mice, dalargin-loaded nanoparticles coated with th...

journal_title：Brain research

authors： Schröder U,Sabel BA

更新日期：1996-02-26 00:00:00

abstract：:We have investigated the influence of central noradrenergic and dopaminergic systems on the susceptibility of rats to seizures in the kainic acid (KA)-model of epilepsy. In the dose range of 0.75 to 10 mg/kg s.c., KA dose-dependently induced characteristic behavioural changes. Partial depletion of noradrenaline (NA) a...

journal_title：Brain research

authors： Baran H,Hörtnagl H,Hornykiewicz O

更新日期：1989-08-28 00:00:00

abstract：:Introduction of 15-30 U of interleukin-2 (IL-2) into the 3rd ventricle of Wistar rats was followed by a marked and significant decrease in neuron discharge frequency in the ventromedial nucleus of hypothalamus and a marked increase in the supraoptic and paraventricular nuclei. The monoclonal antibody ART62 partly bloc...

journal_title：Brain research

authors： Bindoni M,Perciavalle V,Berretta S,Belluardo N,Diamantstein T

更新日期：1988-10-11 00:00:00

abstract：:Previous studies have shown that chronic morphine increases levels of the G-protein subunits Gia and Goa, adenylate cyclase, cyclic AMP-dependent protein kinase, and certain phosphoproteins in the rat locus coeruleus, but not in several other brain regions studied, and that chronic morphine decreases levels of Gia and...

journal_title：Brain research

authors： Terwilliger RZ,Beitner-Johnson D,Sevarino KA,Crain SM,Nestler EJ

更新日期：1991-05-10 00:00:00

abstract：:Samples of 14 brains of autopsied patients suffering from dementia of the Alzheimer type were examined. In Congo red-hemalum stained 14-microns-thick sections of the hippocampus 15 tangle-bearing and 25-30 unaffected nerve cells of area CA1 per case were measured for cell size and nucleolar size utilizing an interacti...

journal_title：Brain research

authors： Gertz HJ,Schoknecht G,Krüger H,Cervos-Navarro J

更新日期：1989-05-22 00:00:00

abstract：:The radioligand [125I]alpha-bungarotoxin (alpha-BTX) has been used to test receptor binding to putative nicotinic cholinergic receptors in the hypothalamus. Using light microscopic autoradiography following third ventricular infusion of the radioligand we have previously demonstrated that in normally cycling rats and ...

journal_title：Brain research

authors： Miller MM,Silver J,Billiar RB

更新日期：1984-01-02 00:00:00

abstract：:Electrical activities of thin hippocampal sections of the guinea pig were studied in vitro during and after administration of black widow spider venom (BSV). In CA3 neurons, BSV induced spontaneous discharges which were suppressed by Co2+ or Mn2+. During BSV administration, trains of potential changes resembling excit...

journal_title：Brain research

authors： Yamamoto C,Matsui H

更新日期：1982-07-29 00:00:00

abstract：:Large neuronal perikarya isolated in bulk fractions from adult bovine ventral spinal cord and examined by electron microscopy have discontinuities in their plasma membrane. A systematic investigation of the possible causes of the membrane defects indicates that the act of mechanical dissociation of the neurons from th...

journal_title：Brain research

authors： Hester S,Capps-Covey P,McIlwain DL

更新日期：1978-12-22 00:00:00

abstract：:Field potentials (FP) recorded from the surface of toad's optic tectum (OT) to electrical stimulation of the contralateral optic nerve (ON) show initial positive deflections P*, followed by negative wave N and positive wave P; the former result from axonal inputs, the latter two resemble excitatory and inhibitory post...

journal_title：Brain research

authors： Schwippert WW,Ewert JP

更新日期：1995-01-09 00:00:00

abstract：:The neurochemical heterogeneity of the rat striatum was assessed in vivo by measuring subregional changes in extracellular dopamine and DOPAC by in vivo electrochemistry and microdialysis in response to amphetamine and the D2 antagonist, (-)-sulpiride. Both in vivo electrochemical and microdialysis experiments indicat...

journal_title：Brain research

authors： Yamamoto BK,Pehek EA

更新日期：1990-01-08 00:00:00

abstract：:Erythropoietin (EPO), a hematopoietic hormonal cytokine induced in response to hypoxia, has neuroprotective effects. EPO receptor (EPOR) is expressed in microglia, resident immune cells in the brain. However, the effect of EPO on microglial activation is not clear. In the present study, we demonstrated that the EPOR i...

journal_title：Brain research

authors： Tamura T,Aoyama M,Ukai S,Kakita H,Sobue K,Asai K

更新日期：2017-05-01 00:00:00

abstract：:Unit activity of locus coeruleus (LC) neurons in rats was investigated. After the animal recovered from anesthesia, the spontaneous activity exhibited periodic bursting discharges at about 15-30 s intervals. The oscillation was observed to last for a long time (1-3 h). It is suggested that many LC neurons exhibited th...

journal_title：Brain research

authors： Akaike T

更新日期：1982-05-13 00:00:00

abstract：:In previous studies we have tested the hypothesis that the termination of the period of sexual behavior in female guinea pigs results from the loss of progestin receptors from hypothalamic cell nuclei. We have shown that hormonal manipulations that delay heat termination also delay loss of hypothalamic nuclear progest...

journal_title：Brain research

authors： Brown TJ,Blaustein JD

更新日期：1986-05-14 00:00:00

abstract：:The molecular mechanisms regulating the retrograde axonal transport of nerve growth factor (NGF) are currently unknown. This study identifies some of the signalling events involved. The phosphoinositide 3-kinase (PI3-kinase) inhibitor wortmannin (1 nmol/eye) irreversibly inhibits the amount of 125I-betaNGF retrogradel...

journal_title：Brain research

authors： Reynolds AJ,Bartlett SE,Hendry IA

更新日期：1998-07-06 00:00:00

abstract：:Neuronal activity in the nucleus parabrachialis medialis (NPBM) was examined in unanesthetized, unrestrained cats during each sleep-waking state. Discharge related to the cardiac cycle was assessed by calculating cross-correlation functions between neuronal and cardiac events (using the peak of the EKG 'R' wave as a r...

journal_title：Brain research

authors： Sieck GC,Harper RM

更新日期：1980-10-20 00:00:00

abstract：:Mutations in two genes, alpha-synuclein and parkin, have been identified as some rare causes for familial Parkinson's disease (PD). alpha-Synuclein and parkin protein have subsequently been identified in Lewy bodies (LB). To gain further insight into the pathogenesis of PD we investigated the role of neurofilament lig...

journal_title：Brain research

authors： Rahner N,Holzmann C,Krüger R,Schöls L,Berger K,Riess O

更新日期：2002-09-27 00:00:00

abstract：:Previous immunocytochemical, physiological, and molecular studies have reported that the Syrian hamster lacks a shortwave-sensitive (S) cone photopigment but retains circadian responses to ultraviolet (UV) light. Using opsin antibodies and a sensitive detection protocol, we here show that S opsin immunoreactivity colo...

journal_title：Brain research

authors： Glösmann M,Ahnelt PK

更新日期：2002-03-01 00:00:00

abstract：:Microtubule organization in type I hair cells has been investigated during the synaptogenesis of vestibular receptors in mammals. The different steps in the maturation of the synapse between the hair cell and the nerve chalice were: a slight symmetrical membrane densification; the appearance of synaptic bodies alongsi...

journal_title：Brain research

authors： Favre D,Dememes D,Sans A

更新日期：1986-02-01 00:00:00

abstract：:We investigated the effect of adenosine A1 receptors on the release of acetylcholine (ACh) and GABA, and on the intracellular calcium concentration ([Ca2+]i) response in cultured chick amacrine-like neurons, stimulated by KCl depolarization. The KCl-induced release of [3H]ACh, but not the release of [14C]GABA, was pot...

journal_title：Brain research

authors： Santos PF,Caramelo OL,Carvalho AP,Duarte CB

更新日期：2000-01-03 00:00:00

abstract：:Our previous single unit and ultrastructural studies of visual cortex of dark-reared rats revealed an impairment of intracortical inhibitory mechanisms [2,3,5]. Neurochemical changes in inhibitory neurotransmitter and/or neuropeptides, such as gamma-aminobutyric acid (GABA) and somatostatin (SS), respectively, may con...

journal_title：Brain research

authors： Benevento LA,Bakkum BW,Cohen RS

更新日期：1995-08-21 00:00:00