Periodic bursting activities of locus coerulleus neurons in the rat.

abstract：:Opiates modulate pain perception at a number of different levels within the central nervous system and the importance of synergistic spinal and supraspinal influences have been well documented. In the present study we demonstrate synergistic interactions between the periaqueductal gray and locus coeruleus. Administere...

journal_title：Brain research

authors： Bodnar R,Paul D,Pasternak GW

更新日期：1991-09-06 00:00:00

abstract：:Cerebellar explants derived from neonatal mice were exposed to cytosine arabinoside, an inhibitor of DNA synthesis. Following such exposure, the cortical regions of the explants contained numerous closely packed large neurons with few intervening elements and without lamination. The surviving large cortical neurons in...

journal_title：Brain research

authors： Seil FJ,Leiman AL,Woodward WR

更新日期：1980-03-31 00:00:00

abstract：:Neurotrophic factors (NTFs), beside regulating neuronal survival in the central and peripheral nervous system, are also involved in the modulation of neuronal function in the adult animal. Both brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) levels are altered in pathological...

journal_title：Brain research

authors： Ciobanu C,Reid G,Babes A

更新日期：2009-08-11 00:00:00

abstract：:The development of glial precursor cells in the mammalian optic nerve depends on retinal ganglion cell (RGC) axons, but the signals that mediate this neuron-to-glia interaction have not been fully characterized. Sonic hedgehog (Shh) is expressed by RGCs, and we showed previously that it is required for the specificati...

journal_title：Brain research

authors： Dakubo GD,Beug ST,Mazerolle CJ,Thurig S,Wang Y,Wallace VA

更新日期：2008-09-04 00:00:00

abstract：:In vitro uptake of labeled serotonin (5-HT) has allowed the radioautographic detection of serotoninergic fibers in the cat spinal cord at thoracic and lumbar levels. The specificity of labeling was ensured by the conditions of incubation ([3H]5-HT was 10(-7) M) and by test control experiments with concomitant 10(-6) M...

journal_title：Brain research

authors： Segu L,Calas A

更新日期：1978-09-29 00:00:00

abstract：:The influence of the cortico-geniculate pathway on identified X and Y lateral geniculate cells was studied by reversibly cooling visual cortical areas 17 and 18. The majority (86.5%) of cells changed their response to visual stimulation when cortex was inactivated, and both X- and Y-cells were modulated by the cortica...

journal_title：Brain research

authors： Geisert EE,Langsetmo A,Spear PD

更新日期：1981-03-16 00:00:00

abstract：:Bcl-2 has been hypothesized to regulate many cellular functions in addition to its well-characterized role in the prevention of programmed cell death. To understand the role of Bcl-2 in regulating cell morphology and to explore the mechanism of this effect, we examined the effects of Bcl-2 overexpression on the morpho...

journal_title：Brain research

authors： Mi Z,Mirnics ZK,Schor NF

更新日期：2006-09-27 00:00:00

abstract：:Long-term exposure to different antidepressant treatments induces increased motor response to central stimulants, due to a selective supersensitivity of dopamine D2 receptors in the limbic areas. Such an effect is accompanied by down-regulation of dopamine D1 receptor number, and by a decreased response of adenylyl cy...

journal_title：Brain research

authors： De Montis MG,Gambarana C,Meloni D,Taddei I,Tagliamonte A

更新日期：1993-03-19 00:00:00

abstract：:Drugs thought to inhibit the actions of protein kinase C (PKC) and cAMP dependent protein kinase (A-kinase) were infused intrathecally into the subarachnoid space of the lumbar region of the spinal cord, and the effects on acoustic startle were measured. Previous work has shown that intrathecal infusion of drugs thoug...

journal_title：Brain research

authors： Boulis NM,Davis M

更新日期：1990-08-20 00:00:00

abstract：:Measurements of extracellular Ca2+ and K+ activities [( Ca2+]o, [K+]o) in the superfused cat carotid body in vitro with triple-barrelled ion-selective electrodes have shown that hypoxia induced a decrease in [Ca2+]o of 0.035 +/- 0.17 mM (mean +/- S.D.; n = 17) and a biphasic change in [K+]o which consisted of an incre...

journal_title：Brain research

authors： Delpiano MA,Acker H

更新日期：1989-03-20 00:00:00

abstract：:The serotonin agonist 8-hydroxy-di-propylaminotetralin (8-OH-DPAT), injected systemically or directly into the medial preoptic area (MPOA), reduces the ejaculatory threshold in male rats. While 8-OH-DPAT has been characterized as an agonist at the 5-HT1A receptor, it also acts at other receptor sites including the dop...

journal_title：Brain research

authors： Matuszewich L,Lorrain DS,Trujillo R,Dominguez J,Putnam SK,Hull EM

更新日期：1999-02-27 00:00:00

abstract：:The stimulated (40 Hz) release of enkephalin from the myenteric plexus can be modulated by multiple types of opiate receptor. The direction of the modulation is not fixed but is bimodal. Both an inhibition and an enhancement of evoked release is observed depending on the concentration of opioid agonist that is used. E...

journal_title：Brain research

authors： Xu H,Smolens I,Gintzler AR

更新日期：1989-12-11 00:00:00

abstract：:Structural equation modeling (SEM) and fMRI were used to test whether changes in the regional activity are accompanied by changes in the inter-regional connectivity as motor practice progresses. Ten healthy subjects were trained to perform finger movement task daily for 4 weeks. Three sessions of fMRI images were acqu...

journal_title：Brain research

authors： Ma L,Wang B,Narayana S,Hazeltine E,Chen X,Robin DA,Fox PT,Xiong J

更新日期：2010-03-08 00:00:00

abstract：:For the purpose of obtaining chemical information about the physiological role of N-acetylaspartylglutamate (NAAG), the release of endogenous NAAG from and the uptake of [3H]NAAG by Guinea pig cerebellar slices were investigated in comparison with L-aspartate (Asp) and L-glutamate (Glu). Although endogenous NAAG was f...

journal_title：Brain research

authors： Sekiguchi M,Okamoto K,Sakai Y

更新日期：1989-03-13 00:00:00

abstract：:One model useful for demonstrating axonal regeneration in the central nervous system is that in which peripheral tissue, particularly the iris, is implanted into the brain or spinal cord. The aim of the present study was to establish the origin of some of the regenerating fibers by the use of an autoradiograhic tracin...

journal_title：Brain research

authors： Schonfeld AR,Katzman R

更新日期：1980-09-22 00:00:00

abstract：:The sites of action of lidocaine on the responses evoked by stimulation of lateral column (LC) and dorsal root (DR) were studied in the isolated, intra-arterially perfused spinal cord of the bullfrog. When the ventral root volley produced by stimulation was abolished by lidocaine, the presynaptic focal potential was a...

journal_title：Brain research

authors： Kuno M,Matsuura S

更新日期：1982-10-07 00:00:00

abstract：:The ventral tegmental area is a site of action by psychostimulants in the production of behavioral sensitization. Recently, G proteins of the ventral tegmental area have been implicated in behavioral sensitization to cocaine. To further investigate the specific role of G proteins, rats were treated with either 15 or 3...

journal_title：Brain research

authors： Striplin CD,Kalivas PW

更新日期：1992-05-08 00:00:00

abstract：:The hypothalamic angiotensin II (Ang II) system plays an important role in pituitary hormone release. Little is known about this system in the mouse brain. We studied the distribution of angiotensin-converting-enzyme (ACE), Ang II, Ang II receptor subtypes, and vasopressin in the hypothalamus of adult male mice. Autor...

journal_title：Brain research

authors： Jöhren O,Imboden H,Häuser W,Maye I,Sanvitto GL,Saavedra JM

更新日期：1997-05-23 00:00:00

abstract：:Many of our everyday actions are only appropriate in certain situations and selecting the appropriate behavior requires that we use current context and previous experience to guide our decisions. The current study examined hippocampal functional connectivity with prefrontal and striatal regions during a task that requ...

journal_title：Brain research

authors： Ross RS,Sherrill KR,Stern CE

更新日期：2011-11-14 00:00:00

abstract：:The research question was, do events arising from rhythmic passive movement of the human leg lead to inhibition of the H reflex pathway in the stationary leg contralateral to that movement? Further, as the angular velocity of the passive movement increases, does the contralateral reflex inhibition also increase? Stabl...

journal_title：Brain research

authors： Collins DF,McIlroy WE,Brooke JD

更新日期：1993-02-12 00:00:00

abstract：:Long-term potentiation (LTP) is a form of synaptic plasticity that may underlie learning and memory. The experiments reported here demonstrate that cocaine blocks the induction of LTP at the excitatory synapses in the CA1 region of the hippocampus, but does not appear to do so by blocking NMDA receptors or channels. O...

journal_title：Brain research

authors： Smith DA,Browning M,Dunwiddie TV

更新日期：1993-04-16 00:00:00

abstract：:Male rats were treated with 10 mg/kg D-fenfluramine (DF) i.p., twice a day for 4 days. Five days later there was a strong reduction (70-100%) in the Bmax of [3H]citalopram binding and the Vmax of [3H]5-HT uptake in cortical and hippocampal synaptosomes; 2 months after the treatment these parameters were reduced by 40-...

journal_title：Brain research

authors： Gobbi M,Mancini L,Presti ML,Mennini T

更新日期：1996-08-19 00:00:00

abstract：:We investigated the influence of muramyl dipeptide (MDP), a cell wall component of Gram-positive bacteria, on cytokine-induced nitric oxide (NO) production in rat primary astrocytes. MDP alone did not induce NO release in astrocyte cultures. However, MDP increased astrocyte NO production and subsequent nitrite accumul...

journal_title：Brain research

authors： Trajkovic V,Samardzic T,Stosic-Grujicic S,Ramic Z,Mostarica Stojkovic M

更新日期：2000-11-10 00:00:00

abstract：:Previous studies on the pathophysiology of white matter anoxic injury have revealed that the Na(+)-Ca2+ exchanger is an important mediator of Ca2+ overload. To date, however, the localization of this key Ca2+ transporter in myelinated axons has not been demonstrated. The present study uses immunofluorescence labeling ...

journal_title：Brain research

authors： Steffensen I,Waxman SG,Mills L,Stys PK

更新日期：1997-11-21 00:00:00

abstract：:The neuropeptide nociceptin/orphanin FQ (N/OFQ), the endogenous agonist of the N/OFQ peptide receptor (NOP receptor), has been demonstrated to be involved in many physiological and pathological functions including pain regulation. In the present study, the involvement of N/OFQ-NOP receptor system in electroacupuncture...

journal_title：Brain research

authors： Fu X,Wang YQ,Wu GC

更新日期：2006-03-17 00:00:00

abstract：:Electroconvulsive stimulation (ECS), the experimental analogue of electroconvulsive therapy (ECT), has been shown to produce both functional and structural effects in the hippocampal formation in infrahuman species. These changes may relate to the antidepressant and cognitive effects of ECT observed in patients treate...

journal_title：Brain research

authors： Lamont SR,Stanwell BJ,Hill R,Reid IC,Stewart CA

更新日期：2005-08-16 00:00:00

abstract：:Considerable knowledge exists concerning the events mediating neuron death following a necrotic insult; prompted by this, there have now been successful attempts to use gene therapy approaches to protect neurons from such necrotic injury. In many such studies, however, it is not clear what sequence of cellular events ...

journal_title：Brain research

authors： Gupta A,Ho DY,Brooke S,Franklin L,Roy M,McLaughlin J,Fink SL,Sapolsky RM

更新日期：2001-07-20 00:00:00

abstract：:There is a population of neurons in the cortex in the middle and anterior part of the superior temporal sulcus (STS) of the monkey with responses which are selective for faces. If, consistent with the effects of damage to the temporal lobe, these neurons are involved in face recognition or in making appropriate social...

journal_title：Brain research

authors： Baylis GC,Rolls ET,Leonard CM

更新日期：1985-09-02 00:00:00

abstract：:The localization of adenosine receptors labelled with [3H]cyclohexyladenosine ([3H]CHA) and adenosine transport sites labelled with [3H]nitrobenzylthioinosine ([3H]NBI) was examined in striatum and superior colliculus (SC) using radioligand binding and lesioning methods. Striatal kainic acid lesions significantly redu...

journal_title：Brain research

authors： Geiger JD

更新日期：1986-01-22 00:00:00

abstract：:The effects of norepinephrine (NE) on inhibitory synaptic potentials were studied on CA1 pyramidal neurons in the hippocampal slice in vitro. Norepinephrine caused the appearance of multiple population spikes in the CA1 region of the hippocampal slice, reminiscent of the actions of gamma-aminobutyric acid (GABA) antag...

journal_title：Brain research

authors： Madison DV,Nicoll RA

更新日期：1988-02-23 00:00:00