Selectivity between faces in the responses of a population of neurons in the cortex in the superior temporal sulcus of the monkey.

Abstract:

:There is a population of neurons in the cortex in the middle and anterior part of the superior temporal sulcus (STS) of the monkey with responses which are selective for faces. If, consistent with the effects of damage to the temporal lobe, these neurons are involved in face recognition or in making appropriate social responses to different individuals, then it might be expected that at least some of these neurons might respond differently to different faces. To investigate whether at least some of these neurons do respond differently to different faces, their responses were measured to a standard set of faces, presented in random sequence using a video framestore. It was found that a considerable proportion of the neurons with face-selective responses tested (34/44 or 77%) responded differently to different faces, as shown by analyses of variance. An index of the discriminability of the most and least effective face stimulus (d') ranged between 0.2 and 5.0 for the different neurons. Although these neurons often responded differently to different faces, they did not usually respond to only one of the faces in the set, so that information that a particular face had been shown was present across an ensemble of neurons, rather than in the responses of an individual neuron. These findings indicate that the responses of these neurons would be useful in providing information on which different behavioral responses made to different faces could be based. These neurons could thus be filters, the output of which could be used for recognition of different individuals and in emotional responses made to different individuals.

journal_name

Brain Res

journal_title

Brain research

authors

Baylis GC,Rolls ET,Leonard CM

doi

10.1016/0006-8993(85)91356-3

subject

Has Abstract

pub_date

1985-09-02 00:00:00

pages

91-102

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(85)91356-3

journal_volume

342

pub_type

杂志文章
  • D2 dopamine receptors in the human brain: heterogeneity based on differences in guanine nucleotide effect on agonist binding, and their presence on corticostriatal nerve terminals.

    abstract::In human brain, regulation of agonist binding to the D2 dopamine receptors by guanine nucleotides is different between several regions. In membranes of the anterior pituitary lobe, agonist binding is fully sensitive to GTP or Gpp(NH)p, whereas it is resistant in membranes of globus pallidus. Both guanine nucleotide-se...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90345-4

    authors: De Keyser J,Walraevens H,De Backer JP,Ebinger G,Vauquelin G

    更新日期:1989-04-10 00:00:00

  • Calcium/calmodulin-dependent protein kinase II and protein phosphatase 2B (calcineurin) immunoreactivity in the rat hippocampus long after ischemia.

    abstract::Calcium/calmodulin-dependent protein kinase II (kinase II) and protein phosphatase 2B (calcineurin) immunoreactivity in the rat hippocampus was studied 100 days after ischemic damage to hippocampal CA1 pyramidal neurons. One-hundred days after ischemia, only a few CA1 pyramidal neurons survived and they exhibited enha...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00382-z

    authors: Onodera H,Yamasaki Y,Kogure K,Miyamoto E

    更新日期:1995-06-26 00:00:00

  • Anatomical and ontogenetic factors producing variation in HVc neuron number in zebra finches.

    abstract::The volume of nucleus HVc of the avian song system varies greatly both among and within songbird species, and is positively correlated to song complexity in many species. Moreover, the number of neurons in HVc predicts the ability of individual zebra finches to imitate song accurately. To better understand this brain/...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02488-x

    authors: Ward BC,Nordeen EJ,Nordeen KW

    更新日期:2001-06-22 00:00:00

  • Synaptic depression at a synapse in Aplysia californica: analysis in terms of a material flow model of neurotransmitter.

    abstract::When a pair of stimuli separated by an appropriate interval is given to the right visceropleural connective of Aplysia californica the amplitude of the second EPSP elicited in cell R15 is usually smaller than the amplitude of the first EPSP. In the present paper we show that this phenomenon, synaptic depression, can b...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(76)90379-6

    authors: Woodson PB,Schlapfer WT,Tremblay JP,Barondes SH

    更新日期:1976-06-04 00:00:00

  • Radial organisation of neurons and dendrites in human cortical areas 25, 32, and 32'.

    abstract::Nissl cytoarchitectural and MAP-2 immunocytochemical evidence is presented for the radial organisation of neurons and neural processes in the human medial prefrontal cortex (mPFC). In Brodmann areas 25, 32, and 32', neuronal cell bodies are organised into short vertical stacks of 15-19 somata with pyramidal cells apic...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2003.08.054

    authors: Gabbott PL

    更新日期:2003-12-05 00:00:00

  • Progressive postnatal dilation of brain ventricles in spontaneously hypertensive rats.

    abstract::Cross-sectional areas of the forebrain ventricles were measured from coronal sections in spontaneously hypertensive rats (SHRs) 4, 8, 12, 16, 21 and 56 weeks of age and in age-matched Wistar--Kyoto (WKY) and Sprague--Dawley (SD) normotensive rats. Progressive ventricular dilation and associated attrition of brain tiss...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90488-9

    authors: Ritter S,Dinh TT

    更新日期:1986-04-09 00:00:00

  • Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.

    abstract::Mouse brain expresses three principal glucose transporters. Glut1 is an endothelial marker and is the principal glucose transporter of the blood-brain barrier. Glut3 and Glut6 are expressed in glial cells and neural cells. A mouse line with a null allele for Glut3 has been developed. The Glut3(-/-) genotype is intraut...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.02.014

    authors: Stuart CA,Ross IR,Howell ME,McCurry MP,Wood TG,Ceci JD,Kennel SJ,Wall J

    更新日期:2011-04-12 00:00:00

  • Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease.

    abstract::Fluoro-Jade B is known as a high affinity fluorescent marker for the localization of neuronal degeneration during acute neuronal distress. However, one study suggested that fluoro-Jade B stains reactive astroglia in the primate cerebral cortex. In this study, we analyzed the staining of fluoro-Jade B alone or combined...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.05.050

    authors: Damjanac M,Rioux Bilan A,Barrier L,Pontcharraud R,Anne C,Hugon J,Page G

    更新日期:2007-01-12 00:00:00

  • Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats.

    abstract::4-hydroxybenzyl alcohol (4-HBA), one of the major active phenolic constituents of Gastrodia elata Blume, a very important traditional Chinese medicinal herb, has been shown to be an effective agent against the central and peripheral nervous disorders. In this study, we attempted to explore the possible mechanisms unde...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.10.037

    authors: Yu SS,Zhao J,Zheng WP,Zhao Y

    更新日期:2010-01-13 00:00:00

  • Neuronal spike activity in the nucleus accumbens of behaving rats during ethanol self-administration.

    abstract::Many lines of evidence support the importance of the nucleus accumbens (NAC) for ethanol-reinforced behavior. The nature of the neuronal activity that occurs in this region during ethanol self-administration is not known. We recorded from ensembles of single-units primarily located within the shell of the NAC during o...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)01245-1

    authors: Janak PH,Chang JY,Woodward DJ

    更新日期:1999-01-30 00:00:00

  • Oral delivery of [D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, synthetic peptide leptin mimetics: Immunofluorescent localization in the mouse hypothalamus.

    abstract::This study describes the localization of [D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, synthetic peptide leptin mimetics, in the hypothalamus of Swiss Webster and C57BL/6J wild-type mice, leptin-deficient ob/ob mice, and leptin-resistant diet-induced obese (DIO) mice. The mice were given [D-Leu-4]-OB3 or MA-[D-Leu-4]-OB3 in 0.3...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2017.03.020

    authors: Anderson BM,Jacobson L,Novakovic ZM,Grasso P

    更新日期:2017-06-01 00:00:00

  • Differential effects of the pyrethroid tetramethrin on tetrodotoxin-sensitive and tetrodotoxin-resistant single sodium channels.

    abstract::The differential effects of the pyrethroid tetramethrin on tetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) single sodium channel currents in rat dorsal root ganglion (DRG) neurons were investigated using the outside-out configuration of patch-clamp technique. Channel conductances were 10.7 and 6.3 pS...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01449-7

    authors: Song JH,Narahashi T

    更新日期:1996-03-18 00:00:00

  • beta-Estradiol induces synaptogenesis in the hippocampus by enhancing brain-derived neurotrophic factor release from dentate gyrus granule cells.

    abstract::We investigated the effect of beta-estradiol (E2) on synaptogenesis in the hippocampus using organotypic hippocampal slice cultures and subregional hippocampal neuron cultures. E2 increased the expression of PSD95, a postsynaptic marker, specifically in stratum lucidum of Cornu Ammonis 3 (CA3SL) in cultured hippocampa...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.02.093

    authors: Sato K,Akaishi T,Matsuki N,Ohno Y,Nakazawa K

    更新日期:2007-05-30 00:00:00

  • Region-, age-, and sex-specific effects of fetal diazepam exposure on the postnatal development of neurosteroids.

    abstract::Fetal exposure to diazepam (DZ), a positive modulator of GABA(A) receptors and an agonist at mitochondrial benzodiazine receptors, induces long-term neural and behavioral effects. This study evaluated whether the early manipulation influenced the normal development of brain levels of neurosteroids or altered steroid a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.10.039

    authors: Kellogg CK,Kenjarski TP,Pleger GL,Frye CA

    更新日期:2006-01-05 00:00:00

  • Diurnal variation in serotonin immunoreactivity in the dorsal raphe nucleus.

    abstract::Serotonin (5-HT) immunostained sections were analyzed using integrated optical density (IOD) measures obtained throughout the dorsal raphe nucleus (DRN) in Mongolian gerbils at selected times during a 12:12 h light:dark cycle. Substantial diurnal variation occurred in 5-HT neuronal staining density, with lowest and hi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.11.053

    authors: Birkett M,Fite KV

    更新日期:2005-02-09 00:00:00

  • Alternative equations for the molluscan ion currents described by Connor and Stevens.

    abstract::The measurements of the ion conductances in molluscan somata, published by Connor and Stevens (1971), were converted into Hodgkin-Huxley like equations. The accuracy of these equations was shown with simulations. An advantage of these equations, compared to the original equations for the fast outward K+(A)-conductance...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90120-4

    authors: De Schutter E

    更新日期:1986-09-10 00:00:00

  • Tyrosine kinase inhibitors, herbimycin A and lavendustin A, block formation of long-term potentiation in the dentate gyrus in vivo.

    abstract::The effects of two specific tyrosine kinase inhibitors on long-term potentiation (LTP) in the dentate gyrus were investigated using anesthetized rats. I.c.v. injection of herbimycin A (1.74 nmol) or lavendustin A (1.31 nmol) before application of tetanic stimulation significantly inhibited the formation of LTP. Howeve...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90315-e

    authors: Abe K,Saito H

    更新日期:1993-09-03 00:00:00

  • Activating deltaPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats.

    abstract::Two pathways that have been shown to mediate cerebral ischemic damage are the MEK/ERK cascade and the pro-apoptotic deltaPKC pathway. We investigated the relationship between these pathways in a rat model of focal ischemia by observing and modifying the activation state of each pathway. The ERK1/2 inhibitor, U0126, in...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.11.051

    authors: Castañeda D,Zhao H,Mochly-Rosen D,Steinberg GK

    更新日期:2009-01-28 00:00:00

  • Dopaminergic involvement in locomotion elicited from the ventral pallidum/substantia innominata.

    abstract::Microinjection of the indirect GABAA antagonist, picrotoxin, or the mu opioid agonist, Tyr-D-Ala-Gly-NMe-Phe-Gly-ol (DAGO), into the ventral pallidum and substantia innominata (VP/SI) increases locomotor activity in rats. The VP/SI has direct and indirect projections to the region of the ventral mesencephalon containi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)91005-l

    authors: Austin MC,Kalivas PW

    更新日期:1991-02-22 00:00:00

  • Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain.

    abstract::Chemokine receptors, and in particular CXCR4 and CCR5 play a key role in the neuropathogenesis of Human Immunodeficiency Virus-1 (HIV)4 associated dementia (HAD). Thus, new insight into the expression of CXCR4 in the central nervous system may help develop therapeutic compounds against HAD. Brain-derived neurotrophic ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.05.086

    authors: Ahmed F,Tessarollo L,Thiele C,Mocchetti I

    更新日期:2008-08-28 00:00:00

  • LRIG1, human EGFR inhibitor, reverses multidrug resistance through modulation of ABCB1 and ABCG2.

    abstract::In our previous study, we have found that leucine-rich repeats and immunoglobulin-like domains 1(LRIG1) can improve the chemosensitivity in U251 cells whereas the role of LRIG1 in multidrug resistance (MDR) remains unknown. Here, we reported that LRIG1 can reverse MDR by inhibiting epidermal growth factor (EGF) recept...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.03.023

    authors: Liu B,Guo Z,Dong H,Daofeng T,Cai Q,Ji B,Zhang S,Wu L,Wang J,Wang L,Zhu X,Liu Y,Chen Q

    更新日期:2015-06-22 00:00:00

  • Effects of methyl-beta-cyclodextrin on blood-brain barrier permeability in angiotensin II-induced hypertensive rats.

    abstract::The blood-brain barrier (BBB) permeability primarily increases in cerebral venules during acute hypertension. Methyl-β-cyclodextrin (MβCD), a cholesterol-depleting agent, decreases the expression of caveolins disrupting caveolar structures. We aimed to determine the effects of MβCD on the BBB permeability of angiotens...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.03.024

    authors: Atış M,Akcan U,Uğur Yılmaz C,Orhan N,Düzgün P,Deniz Ceylan U,Arıcan N,Karahüseyinoğlu S,Nur Şahin G,Ahıshalı B,Kaya M

    更新日期:2019-07-15 00:00:00

  • Spatial distribution of evoked potentials in the inferior olivary nucleus by stimulation of the visual afferents in the rat.

    abstract::Visual pathways (optic disc, optic nerve and pretectal regions) were electrically stimulated and evoked potentials were explored throughout the inferior olive in the anesthetized rat. Responsive areas were identified as the caudal half of the dorsal cap, nucleus beta and the most caudal region of subnucleus c of the m...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91060-7

    authors: Akaike T

    更新日期:1986-03-12 00:00:00

  • Hypoglycemia enhances the expression of mRNA encoding beta-amyloid precursor protein in rat primary cortical astroglial cells.

    abstract::Deposition of beta-amyloid (A beta) is a characteristic feature of the pathology of Alzheimer's disease (AD). Since glucose metabolism and the consequential ATP production are depressed in the temporal and parietal regions of the cortex in patients with AD, we designed the present study to investigate the possible rol...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00827-5

    authors: Shi J,Xiang Y,Simpkins JW

    更新日期:1997-10-24 00:00:00

  • Early developmental exposure to benzodiazepine ligands alters brain 31P-NMR spectra in young adult rats.

    abstract::Alterations in brain high energy phosphate compounds, using 31P-NMR (nuclear magnetic resonance) spectroscopy, were measured in vivo in young adult (3-4 months) rats following prenatal exposure to ligands acting specifically at benzodiazepine (BDZ) binding sites. The exposure induced a decrease in intracellular pH tha...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91202-r

    authors: Miranda R,Ceckler T,Guillet R,Kellogg C

    更新日期:1990-01-01 00:00:00

  • Adult naris closure profoundly reduces tyrosine hydroxylase expression in mouse olfactory bulb.

    abstract::Peripheral afferent innervation appears to be required for the expression of the dopamine phenotype in the rodent main olfactory bulb. Experiments utilizing neonatal naris closure as a means of sensory deprivation also suggest that odor-induced afferent activity is required for the expression of the phenotype. These e...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91023-l

    authors: Baker H,Morel K,Stone DM,Maruniak JA

    更新日期:1993-06-18 00:00:00

  • Description and quantification of cocaine withdrawal signs in Planaria.

    abstract::Previous work provided indirect evidence that planarians undergo abstinence-induced withdrawal from cocaine. The present study's purpose was to determine if planarians display withdrawal signs and, if so, to quantify the behaviors. Planarians were soaked in cocaine then transferred to either the same cocaine concentra...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.10.052

    authors: Raffa RB,Desai P

    更新日期:2005-01-25 00:00:00

  • Oxidative stress induced by administration of the neuroleptic drug haloperidol is attenuated by higher doses of haloperidol.

    abstract::The effect of haloperidol administration on lipid peroxidation and glutathione/protein thiol homeostasis in the brain was examined 4 h following subcutaneous administration of a single dose of haloperidol; 1.0, 1.5, 2.0 or 2.5 mg/kg b.wt. Glutathione (GSH) levels decreased significantly in cortex, striatum and midbrai...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91058-m

    authors: Shivakumar BR,Ravindranath V

    更新日期:1992-11-13 00:00:00

  • Human mesenchymal stem cell transplantation protects against cerebral ischemic injury and upregulates interleukin-10 expression in Macacafascicularis.

    abstract::Mesenchymal stem cell (MSC) transplantation has been reported to improve neurologic function after ischemic injury. However, the detailed mechanisms by which MSCs promote functional recovery are not fully understood. Interleukin-10 (IL-10) is a well-known anti-inflammatory cytokine with neuroprotective effects with re...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.03.080

    authors: Li J,Zhu H,Liu Y,Li Q,Lu S,Feng M,Xu Y,Huang L,Ma C,An Y,Zhao RC,Wang R,Qin C

    更新日期:2010-06-02 00:00:00

  • Transneuronal tracing of neural pathways controlling abdominal musculature in the ferret.

    abstract::Abdominal musculature participates in generating a large number of behaviors and protective reflexes, although each abdominal muscle is frequently activated differentially during particular motor responses. For example, rectus abdominis has been reported to play less of a role in respiration than other abdominal muscl...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02597-5

    authors: Billig I,Hartge K,Card JP,Yates BJ

    更新日期:2001-08-31 00:00:00