In vivo type 1 cannabinoid receptor mapping in the 6-hydroxydopamine lesion rat model of Parkinson's disease.

abstract：:Frequency-current curves for CA1 hippocampal pyramidal neurons are shown to have basically the same shape as those for spinal motoneurones, with a region of shallow slope at low frequencies, preceding a sleep linear or upward convex region at higher frequencies. The frequency range is, however, displaced towards lower...

journal_title：Brain research

authors： Gustafsson B,Wigström H

更新日期：1981-11-02 00:00:00

abstract：:Hybridization histochemical and immunohistochemical methods were used to characterize the distribution of corticotropin-releasing factor (CRF) messenger RNA (mRNA) and peptide, respectively, in the central auditory system of the rat. Cell bodies expressing CRF mRNA and/or immunoreactivity (IR) were detected at each le...

journal_title：Brain research

authors： Imaki J,Imaki T,Vale W,Sawchenko PE

更新日期：1991-04-26 00:00:00

abstract：:We have examined the saturation features (Kd and Bmax) of [3H]naloxone binding in rat brain regions in cytoarchitectonically intact tissues of naive, morphine dependent and precipitated withdrawal states using quantitative film autoradiography. Sixty-one saturation experiments in 13 regions of naive rat brains yielded...

journal_title：Brain research

authors： Geary WA 2nd,Wooten GF

更新日期：1985-12-23 00:00:00

abstract：:Rats trained to walk in a moving belt apparatus were subjected to a partial (fornix-fimbria (FF] or total (fornix-fimbria + cingulum bundles (FF + CB] chemical denervation of the dorsal serotonergic afferent pathways to the hippocampus. After chronic alcohol treatment that resulted in tolerance development to the moto...

journal_title：Brain research

authors： Speisky MB,Kalant H

更新日期：1985-02-11 00:00:00

abstract：:It has been demonstrated that repeated, subcutaneous administration of 3,4-methylenedioxymethamphetamine (MDMA) to rats, guinea pigs, and squirrel monkeys produces long-lasting depletions of serotonin (5-hydroxytryptamine; 5-HT) in several brain regions. Since evidence of degenerating 5-HT neurons has been observed in...

journal_title：Brain research

authors： Kleven MS,Woolverton WL,Seiden LS

更新日期：1989-05-29 00:00:00

abstract：:Activation of immune cells by pathogens induces the release of a variety of proinflammatory cytokines, including IL-1 beta and TNF-alpha. Previous studies using IL-1 beta have demonstrated that this cytokine can alter brain function, resulting in a variety of 'illness responses' including increased sleep, decreased fo...

journal_title：Brain research

authors： Watkins LR,Goehler LE,Relton J,Brewer MT,Maier SF

更新日期：1995-09-18 00:00:00

abstract：:Although the role of STAT3 in cell physiology and tissue development has been largely investigated, its involvement in the development and maintenance of nervous tissue and in the mechanisms of neuroprotection is not yet known. The potentially wide range of STAT3 activities raises the question of tissue- and gender-sp...

journal_title：Brain research

authors： Di Domenico F,Casalena G,Sultana R,Cai J,Pierce WM,Perluigi M,Cini C,Baracca A,Solaini G,Lenaz G,Jia J,Dziennis S,Murphy SJ,Alkayed NJ,Butterfield DA

更新日期：2010-11-29 00:00:00

abstract：:We studied the effects of nitric oxide (NO) and the NO-releasing agents sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP) and isosorbide dinitrate (ISDN) on N-methyl-D-aspartate (NMDA)-induced increases in intracellular Ca2+ ([Ca2+]i), whole-cell patch-clamp currents and on glutamate-stimulated [3H]di...

journal_title：Brain research

authors： Hoyt KR,Tang LH,Aizenman E,Reynolds IJ

更新日期：1992-10-02 00:00:00

abstract：:This study investigated the effects of N6-cyclopentyladenosine (CPA), a potent and selective adenosine A1 receptor (A1R) agonist in normal and nerve-injured rats and mechanisms of its action by behavioral tests and electrophysiological technique. The results showed: (1) In normal rats, intraperitoneal administration o...

journal_title：Brain research

authors： Gong QJ,Li YY,Xin WJ,Wei XH,Cui Y,Wang J,Liu Y,Liu CC,Li YY,Liu XG

更新日期：2010-11-18 00:00:00

abstract：:This manuscript describes the use of staining of Fos-related antigens (FRAs) as markers for changes in neuronal activity. The model system consisted of the tuberoinfundibular dopamine (TIDA) neurons located in the arcuate nucleus of the hypothalamus. Under normal conditions, these neurons are devoid of c-Fos staining ...

journal_title：Brain research

authors： Hoffman GE,Le WW,Abbud R,Lee WS,Smith MS

更新日期：1994-08-22 00:00:00

abstract：:Transcranial magnetic stimulation (TMS) of human lower limb motor cortex paired with common peroneal nerve electrical stimulation produces a lasting modulation of motor cortex excitability following the principles of spike-timing-dependent plasticity. We previously demonstrated that this "paired associative stimulatio...

journal_title：Brain research

authors： Jayaram G,Santos L,Stinear JW

更新日期：2007-06-11 00:00:00

abstract：:The behavioral effects of lesions of the nucleus basalis magnocellularis (NBM) on two spatial discrimination tasks (place navigation and cross maze) were examined in the rat. These tasks were designed to test reference memory. Lesions by bilateral injection of ibotenic acid into the NBM led to a severe and permanent i...

journal_title：Brain research

authors： Mayo W,Kharouby M,Le Moal M,Simon H

更新日期：1988-07-12 00:00:00

abstract：:Whereas the role of the hippocampus for spatial learning and long-term memory is largely undisputed, there is less evidence for a participation of hippocampal structures in spatial working memory operations. In an fMRI study (functional magnetic resonance imaging), we therefore examined the role of the hippocampus dur...

journal_title：Brain research

authors： Toepper M,Markowitsch HJ,Gebhardt H,Beblo T,Thomas C,Gallhofer B,Driessen M,Sammer G

更新日期：2010-10-01 00:00:00

abstract：:Using the histochemical Timm sulphide silver method, a strain-specific, increased stainability of the cell bodies of the dentate granule cells and the hippocampal pyramidal cells was observed in the inbred Kyoto rat. The resulting dense staining which also includes neurons in the neocortex and cerebellum can be used a...

journal_title：Brain research

authors： Finsen B,Zimmer J

更新日期：1986-09-01 00:00:00

abstract：:Previous studies have indicated that central sensitization is a state of increased excitability of nociceptive neurons in the spinal dorsal horn following peripheral tissue injury and/or inflammation and astrocytes play an important role in the central sensitization. The current study investigated the role of amino ac...

journal_title：Brain research

authors： Wang J,Geng B,Shen HL,Xu X,Wang H,Wang CF,Ma JL,Wang ZP

更新日期：2012-04-17 00:00:00

abstract：:Based on pharmacological evidence that inhibitory amino acids mediate vaginocervical mechano-stimulation produced analgesia (VSPA), we hypothesized that inhibitory amino acids would be released endogenously in the spinal cord in response to vaginocervical mechano-stimulation (VS). This hypothesis was tested by HPLC an...

journal_title：Brain research

authors： Masters DB,Jordan F,Beyer C,Komisaruk BR

更新日期：1993-09-10 00:00:00

abstract：:The present study examined the ability of antioxidant effects of angiotensin-converting enzyme (ACE) inhibitor, imidaprilat, on the synergistic effect of bisphenol A and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical (*OH) formation and dopamine (DA) efflux in extracellular fluid of rat striatum. Bi...

journal_title：Brain research

authors： Obata T

更新日期：2006-02-03 00:00:00

abstract：:Portions of cerebellar cortex, particularly Larsell's hemisphere VI, have been identified as involved but not essential for the acquisition and retention of classical conditioning of the nictitating membrane (NM) response in rabbit. The present experiment was undertaken to examine the effect of lesions of cerebellar c...

journal_title：Brain research

authors： Woodruff-Pak DS,Lavond DG,Logan CG,Steinmetz JE,Thompson RF

更新日期：1993-04-09 00:00:00

abstract：:The participation of amygdaloid and striatal structures in the various signs of morphine withdrawal syndrome (MWS) has been investigated using two complementary approaches: intracerebral application of naloxone in various nuclei of dependent rats and effects of various lesions and transections on systemically induced ...

journal_title：Brain research

authors： Calvino B,Lagowska J,Ben-Ari Y

更新日期：1979-11-09 00:00:00

abstract：:Previous studies showed the role of basolateral amygdala (BLA) in cannabinoid-induced antinociception. Furthermore, the nucleus accumbens (NAc) plays an important role in mediating the suppression of pain in animal models. The present study extended the role of dopamine receptors within the NAc in antinociceptive effe...

journal_title：Brain research

authors： Haghparast A,Ghalandari-Shamami M,Hassanpour-Ezatti M

更新日期：2012-08-30 00:00:00

abstract：:Electrical and pharmacological properties of currents induced by compounds having affinities for putative sigma receptors were investigated with NCB20 cells by use of the whole-cell patch-clamp technique. Antipsychotics and naloxone induced inward currents with a decrease in membrane conductance at a holding potential...

journal_title：Brain research

authors： Morio Y,Tanimoto H,Yakushiji T,Morimoto Y

更新日期：1994-02-21 00:00:00

abstract：:We used triple-labeling immunohistochemistry in rat midbrain sections to identify dopaminergic neurons that contain either one or both of the calcium-binding proteins, calretinin (CR) and calbindin-D28k (CB). Midbrain dopaminergic neurons were immunohistochemically labeled for tyrosine hydroxylase (TH), CR, and CB. In...

journal_title：Brain research

authors： Nemoto C,Hida T,Arai R

更新日期：1999-10-30 00:00:00

abstract：:A pair of adult molluscan neurons (L5 and R5) are known to sprout and form a new electrical synapse following axotomy. Additionally, certain forms of stress can elicit restricted sprouting of neurons L5 and R5 within the intact nervous system. This study found that the strength of 5-5 electrical coupling was increased...

journal_title：Brain research

authors： Bulloch AG

更新日期：1985-09-23 00:00:00

abstract：:Methionine (Met) enkephalin is detectable in rat hypothalamic and neurointermediate lobe (NIL) tissue extracts using a specific radioimmunoassay. Reversed-phase HPLC revealed that only the pentapeptide form was present in the extracts. Total amounts of Met-enkephalin in extracts containing the median eminence (ME), su...

journal_title：Brain research

authors： Jessop D,Sidhu R,Lightman SL

更新日期：1990-05-14 00:00:00

abstract：:Rhythmical scratching movements of the hindlimb were evoked in decerebrate and decapitate cats by stimulation of C1-C2 segments of the spinal cord. Movements of the limb and electrical activity of its muscles were recorded. All muscles were divided into two groups according to their activity. Muscles of the first grou...

journal_title：Brain research

authors： Deliagnina TG,Feldman AG,Gelfand IM,Orlovsky GN

更新日期：1975-12-19 00:00:00

abstract：:Respiratory neurons were recorded with microelectrodes in the medullary dorsal respiratory group of pentobarbital-anesthetized cats. The animals were ventilated with a phrenic-driven servorespirator that allowed manipulation of phasic volume feedback. By increasing or decreasing the gain of the servorespirator, graded...

journal_title：Brain research

authors： Baker JP Jr,Remmers JE

更新日期：1980-11-03 00:00:00

abstract：:Retrograde transport of horseradish peroxidase (HRP) was used to identify supraependymal neurons projecting to the pituitary gland in the hamster. Supraependymal neurons overlying the median eminence were labeled by HRP injections into the neural and intermediate lobes of the pituitary gland; no neurons were labeled f...

journal_title：Brain research

authors： Michael DB,Hazlett JC,Mitchell JA

更新日期：1989-01-30 00:00:00

abstract：:We previously reported that aquaporin 4 (AQP4) played a critical role in formation of brain edema and the altered expression of dystroglycan (DG) could relate with AQP4 expression after traumatic brain injury (TBI). However the mechanisms of this process remain unclear. DG was showed could act as a scaffold involved i...

journal_title：Brain research

authors： Zhang G,Ma P,Wan S,Xu J,Yang M,Qiu G,Zhuo F,Xu S,Huo J,Ju Y,Liu H

更新日期：2019-10-15 00:00:00

abstract：:Neonatal rat superior cervical ganglia were mechanically dissociated, and the sympathetic neurons grown in dispersed cell cultures. Intracellular microelectrodes were used to study the effects of tetraethylammonium (TEA+), a blocker of outward K+ currents, on the excitable properties of these neurons. Addition of TEA+...

journal_title：Brain research

authors： Suppes T

更新日期：1984-02-20 00:00:00

abstract：:Hippocampal cholinergic neurons are sensitive to acute ethanol administration, and specific alterations are seen in the functioning of these neurons following chronic ethanol. The present study examined the effects of chronic ethanol exposure and withdrawal on the sensitivity of the hippocampus to local injection of p...

journal_title：Brain research

authors： Gonzalez LP

更新日期：1985-06-03 00:00:00