Shape of frequency-current curves in CAI pyramidal cells in the hippocampus.

abstract：:Previous studies have shown that microinjection of morphine into the prefrontal ventrolateral orbital cortex (VLO) produces antinociception. The current study examined whether gamma-aminobutyric acid (GABA) containing neurons in the VLO were involved in this antinociception. Under light anesthesia, the GABA(A) recepto...

journal_title：Brain research

authors： Qu CL,Tang JS,Jia H

更新日期：2006-02-16 00:00:00

abstract：:Perceptual performance in persons with hearing loss, especially those using devices to restore hearing, is not fully predicted by traditional audiometric measurements designed to evaluate the status of peripheral function. The integrity of auditory brainstem synapses may vary with different forms of hearing loss, and ...

journal_title：Brain research

authors： McGuire B,Fiorillo B,Ryugo DK,Lauer AM

更新日期：2015-04-24 00:00:00

abstract：:The cellular origin and degree of collateralization of the subthalamostriatal, subthalamonigral and subthalamopallidal projections in the squirrel monkey (Saimiri sciureus) were studied using lectin-conjugated horseradish peroxidase (WGA-HRP), Nuclear yellow (NY) and Fast blue (FB) as retrograde tracers. In a first ex...

journal_title：Brain research

authors： Parent A,Smith Y

更新日期：1987-12-15 00:00:00

abstract：:The effect of a dihydropyridine Ca2+ antagonist, cilnidipine, on voltage-dependent Ca2+ channels was studied in acutely dissociated rat CA1 pyramidal neurons using the nystatin-perforated patch recording configuration under voltage-clamp conditions. Cilnidipine had no effect on low-voltage-activated (LVA) Ca2+ channel...

journal_title：Brain research

authors： Murai Y,Uneyama H,Ishibashi H,Takahama K,Akaike N

更新日期：2000-01-31 00:00:00

abstract：:Adenine and guanine nucleotides have been shown to exert multiple roles in central and peripheral nervous systems, and the sequential breakdown of these nucleotides by enzymatic systems is an important step in the modulation of their extracellular effects. The aim of this study was to investigate whether nucleotide hy...

journal_title：Brain research

authors： Cruz Portela LV,Oses JP,Silveira AL,Schmidt AP,Lara DR,Oliveira Battastini AM,Ramirez G,Vinadé L,Freitas Sarkis JJ,Souza DO

更新日期：2002-09-20 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-like immunoreactivity was examined in the rat olfactory bulb by an immunohistochemical method using antiserum against the tripeptide TRH. TRH-immunoreactive neurons and neuronal processes were localized in both main and accessory olfactory bulb, including the glomerular layer, exter...

journal_title：Brain research

authors： Tsuruo Y,Hökfelt T,Visser TJ

更新日期：1988-04-26 00:00:00

abstract：:The biosynthetic activity of extra-hypothalamic vasopressin (VP) neurons in the bed nucleus of the stria terminalis (BNST) is regulated by gonadal steroids. These neurons have also been implicated in a number of behaviors that are impaired in aging. We previously reported that VP mRNA labelling in the BNST is decrease...

journal_title：Brain research

authors： Dobie DJ,Miller MA,Raskind MA,Dorsa DM

更新日期：1992-06-26 00:00:00

abstract：:The purposes of this study were to examine responses of superficial (depth <300 microm) and deeper thoracic spinal neurons to chemical stimulation of cardiac afferents and effects of descending influences on these neurons. Extracellular potentials of single T(3)-T(4) neurons were recorded in pentobarbital anesthetized...

journal_title：Brain research

authors： Qin C,Chandler MJ,Miller KE,Foreman RD

更新日期：2003-01-03 00:00:00

abstract：:Hippocampal CA1 pyramidal neurons undergo delayed neurodegeneration after transient forebrain ischemia, and the phenomenon is dependent upon hyperactivation of l-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) subtype of glutamate receptors, resulting in aberrant intracellular calcium influx. The GluR2 sub...

journal_title：Brain research

authors： Kaur J,Zhao Z,Geransar RM,Papadakis M,Buchan AM

更新日期：2006-02-23 00:00:00

abstract：:Modulation of gamma-aminobutyric acid (GABA)-mediated inhibition, and glutamate-mediated excitation by highly selective mu and delta opioid agonists was studied using intracellular recordings of CA1 pyramidal neuron synaptic responses in superfused hippocampal slices. Equimolar concentrations of the selective mu agoni...

journal_title：Brain research

authors： Lupica CR,Proctor WR,Dunwiddie TV

更新日期：1992-10-16 00:00:00

abstract：:Rats were given sham, cortical, or hippocampal lesions and sacrificed 7 or 28 days following surgery. Levels of norepinephrine, dopamine, and the major dopamine metabolites, 3,4-dihydroxyphenylacetic acid and homovanillic acid (HVA), were assayed in 3 brain regions. At day 7 there was a decrease in dopamine utilizatio...

journal_title：Brain research

authors： Springer JE,Isaacson RL

更新日期：1982-12-02 00:00:00

abstract：:Extracellular action potentials were recorded from 691 neurons in the ventromedial hypothalamus (VMH) of urethane anesthetized female rats under acute and chronic sham-operated and hyperprolactinemic conditions. Hyperprolactinemia was produced by transplanting pituitaries under the kidney capsules. Neuronal excitabili...

journal_title：Brain research

authors： Moss RL,Chan A,Dudley CA

更新日期：1985-11-04 00:00:00

abstract：:Recently, Somberg, in a preliminary report (1983), noted that electrical stimulation of the area postrema causes an increase in coronary vascular resistance. The increase in resistance was mediate by an increase in sympathetic activity as it was counteracted by alpha-adrenergic receptor blockade. The purpose of our st...

journal_title：Brain research

authors： Gatti PJ,Dias Souza J,Gillis RA

更新日期：1988-05-17 00:00:00

abstract：:Pro-social lying, which serves to benefit listeners, is considered more socially and morally acceptable than anti-social lying, which serves to harm listeners. However, it is still unclear whether the neural mechanisms underlying the moral judgment of pro-social lying differ from those underlying the moral judgment of...

journal_title：Brain research

authors： Hayashi A,Abe N,Fujii T,Ito A,Ueno A,Koseki Y,Mugikura S,Takahashi S,Mori E

更新日期：2014-03-27 00:00:00

abstract：:The frequency-dependent effect of various anticonvulsant drugs on the conduction in central axons was studied in the corpus callosum of rat and guinea pig brain slices from the parietal region. Extracellularly recorded compound action potentials (CAPs) were evoked by either single stimulus or high frequency stimulatio...

journal_title：Brain research

authors： Silberstein E,Schleifstein-Attias D,Grossman Y

更新日期：1992-07-24 00:00:00

abstract：:Two monkeys were trained to perform 3 kinds of spatial tasks (right-left DR, up-down DR, and conditional position discrimination with delay). In the conditional position task, the animal was required to respond to the right (left) choice key when the cue had been presented on the upper (lower) position. Single unit ac...

journal_title：Brain research

authors： Niki H,Watanabe M

更新日期：1976-03-19 00:00:00

abstract：:Astrogliogenesis in the human fetal cerebellum was examined in 46 cerebella obtained from hysterotomy specimens ranging between 9 and 20 weeks of ovulation age. By correlating the results obtained by rapid Golgi and Golgi-Cox methods, the indirect immunofluorescence technique for glial fibrillary acidic protein, and e...

journal_title：Brain research

authors： Choi BH,Lapham LW

更新日期：1980-05-26 00:00:00

abstract：:We investigated the effects of a novel Na(+)/H(+) exchanger-1 (NHE-1) inhibitor KR-33028 on glutamate excitotoxicity in cultured neuron cells in vitro and cerebral infarct in vivo by comparing its potency with that of zoniporide, a well-known, highly potent NHE-1 inhibitor. KR-33028 inhibited NHE-1 activation in a con...

journal_title：Brain research

authors： Lee BK,Lee DH,Park S,Park SL,Yoon JS,Lee MG,Lee S,Yi KY,Yoo SE,Lee KH,Kim YS,Lee SH,Baik EJ,Moon CH,Jung YS

更新日期：2009-01-12 00:00:00

abstract：:The purpose of this study was to ascertain whether visual acuity or contrast sensitivity function (CSF) is proportional to visual cortical function based on fMRI volume and level of activation or Z-score. Forced choice procedures were utilized to measure the monocular log minimal angle of resolution (logMAR) visual ac...

journal_title：Brain research

authors： Leguire LE,Algaze A,Kashou NH,Lewis J,Rogers GL,Roberts C

更新日期：2011-01-07 00:00:00

abstract：:The effects of prostaglandin E1 (PGE1) on porcine cerebral arteries were studied in the absence and presence of cyclooxygenase inhibitors, 5 x 10(-6) M indomethacin or 10(-4) M aspirin. In preparations placed at a resting tension, 3 x 10(-9) to 10(-6) M PGE1 caused dose-dependent contractions. In prostaglandin F2 alph...

journal_title：Brain research

authors： Fukuda S,Taga K,Tsukui A,Nishimura N,Kumagai Y,Shimoji K

更新日期：1989-09-04 00:00:00

abstract：:An antagonist to amino acid evoked excitation, gamma-D-glutamylglycine (gamma-DGG) inhibits, dose-dependently, nociceptive C-fibre evoked field potentials and neuronal discharges in single nociceptive neurons in rat spinal cord. It is concluded that amino acids are possible transmitter substance(s) in nociceptive affe...

journal_title：Brain research

authors： Schouenborg J,Sjölund BH

更新日期：1986-08-06 00:00:00

abstract：:It has been reported that L-glutamate (L-glu) microinjection into the hypothalamic paraventricular nucleus (PVN) evokes pressor and tachycardiac responses in unanesthetized rats. In the present study the hypothesis was tested that a local nitric oxide (NO)-guanylate cyclase interaction mediates cardiovascular effects ...

journal_title：Brain research

authors： Busnardo C,Crestani CC,Tavares RF,Resstel LB,Correa FM

更新日期：2010-07-16 00:00:00

abstract：:The principal finding in this study is that the callosal projection to the occipital cortex in rats and mice follows a complex and highly reproducible pattern which has not previously been described in detail. In some regions, the callosal projection is associated with well defined cytoarchitectonic boundaries such as...

journal_title：Brain research

authors： Cusick CG,Lund RD

更新日期：1981-06-15 00:00:00

abstract：:Whether functional changes of the non-primary motor areas, e.g., dorsal premotor (PMd) and supplementary motor (SMA) areas, after stroke, reflect reorganization phenomena or recruitment of a pre-existing motor network remains to be clarified. We hypothesized that cellular changes in these areas would be consistent wit...

journal_title：Brain research

authors： Cirstea CM,Nudo RJ,Craciunas SC,Popescu EA,Choi IY,Lee P,Yeh HW,Savage CR,Brooks WM

更新日期：2012-06-29 00:00:00

abstract：:In an effort to further characterize the proteins of the auditory nerve, the effects of hair cell loss on rapidly transported proteins of the auditory nerve were studied. The effects were studied in the waltzing guinea pig, a genetically deaf animal which displays an age-dependent loss of sensory cells, and in normal ...

journal_title：Brain research

authors： Wenthold RJ,McGarvey ML

更新日期：1982-12-16 00:00:00

abstract：:Synapses onto dendritic spines in the lateral amygdala formed by afferents from the auditory thalamus represent a site of plasticity in Pavlovian fear conditioning. Previous work has demonstrated that thalamic afferents synapse onto LA spines expressing glutamate receptor (GluR) subunits, but the GluR subunit distribu...

journal_title：Brain research

authors： Radley JJ,Farb CR,He Y,Janssen WG,Rodrigues SM,Johnson LR,Hof PR,LeDoux JE,Morrison JH

更新日期：2007-02-23 00:00:00

abstract：:Electrophysiological studies suggest that an increase in excitatory amino acid release may occur in the locus coeruleus during opiate withdrawal. The present study examined directly by microdialysis in anesthetized rats the effect of naltrexone-precipitated opiate withdrawal on the efflux of excitatory amino acids in ...

journal_title：Brain research

authors： Aghajanian GK,Kogan JH,Moghaddam B

更新日期：1994-02-04 00:00:00

abstract：:We examined the effect of CP-154,526 on cardiovascular changes elicited in conscious rabbits by stressful stimuli (loud sound, cage move, pinprick, formaldehyde vapour and air-jet stress). CP-154,526 substantially reduced pressor and heart rate responses to these stimuli (both vagally and sympathetically mediated), an...

journal_title：Brain research

authors： Nalivaiko E,Blessing WW

更新日期：2004-08-13 00:00:00

abstract：:In over half a century numerous studies have demonstrated that different odorants produce individually different spatial patterns of neural receptor activity on the olfactory mucosa. However, the thought that these differential activity patterns could be the neural code underlying olfactory perception has not been tes...

journal_title：Brain research

authors： Kent PF,Mozell MM,Youngentob SL,Yurco P

更新日期：2003-08-15 00:00:00

abstract：:Lysosomal storage diseases are a heterogeneous group of hereditary disorders characterized by a deficiency in lysosomal function. Although these disorders differ in their etiology and phenotype those that affect the nervous system generally manifest as a profound deterioration in neurologic function with age. Over the...

journal_title：Brain research

authors： Phinney DG,Isakova IA

更新日期：2014-07-21 00:00:00