Renormalization of regional brain blood flow during prolonged mild hypoxic exposure in rats.

Abstract:

:In this study, we measured regional brain blood flow (BF) in rats during hypoxic exposure. Our data show the hypoxia-induced brain blood flow increase returned to baseline within 1 week as blood hemoglobin increased. Because this return to baseline occurred before capillary angiogenesis, this result suggests that the mechanism for brain blood flow renormalization during prolonged hypoxia exposure is more likely related to the increased systemic arterial oxygen carrying capacity than to local tissue hypoxia that persists for at least 2 weeks.

journal_name

Brain Res

journal_title

Brain research

authors

Xu K,Puchowicz MA,LaManna JC

doi

10.1016/j.brainres.2004.08.046

subject

Has Abstract

pub_date

2004-11-19 00:00:00

pages

188-91

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(04)01338-1

journal_volume

1027

pub_type

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