Expression of c-fos, fos B, and egr-1 in the medial preoptic area and bed nucleus of the stria terminalis during maternal behavior in rats.

abstract：:In the striatum and hippocampus, there is a loss of sensitivity to muscarinic agonists with age which has been traced to events early in the signal transduction pathway. Our laboratory has therefore focussed on investigations at this level. The current experiments investigate the effects of age on G-protein/receptor i...

journal_title：Brain research

authors： Anson RM,Cutler R,Joseph JA,Yamagami K,Roth GS

更新日期：1992-12-11 00:00:00

abstract：:The roles of noradrenergic and serotonergic projections to the hippocampus were investigated with respect to their involvement in the intracranial self-stimulation of this structure. In the first study, 6-hydroxydopamine-induced lesions of the dorsal tegmental noradrenergic bundle, which depleted hippocampal NE by 97%...

journal_title：Brain research

authors： van der Kooy D,Fibiger HC,Phillips AG

更新日期：1977-11-04 00:00:00

abstract：:Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder associated with premutation alleles of the FMR1 gene that is characterized by progressive action tremor, gait ataxia, and cognitive decline. Recent studies of mitochondrial dysfunction in FXTAS have suggested that iron dysre...

journal_title：Brain research

authors： Ariza J,Steward C,Rueckert F,Widdison M,Coffman R,Afjei A,Noctor SC,Hagerman R,Hagerman P,Martínez-Cerdeño V

更新日期：2015-02-19 00:00:00

abstract：:Testosterone's (T) aggression-enhancing effects may be mediated in part by its 5alpha-reduced, 3-hydroxysteroid dehydrogenized metabolite 5alpha-androstane-3alpha,17beta-diol (3alpha-diol). To test this hypothesis, in Expt. 1 gonadectomized (gdx) C21 mice were administered T, 3alpha-diol, or vehicle and were observed ...

journal_title：Brain research

authors： Frye CA,Rhodes ME,Walf A,Harney JP

更新日期：2002-09-06 00:00:00

abstract：:Whereas the role of the hippocampus for spatial learning and long-term memory is largely undisputed, there is less evidence for a participation of hippocampal structures in spatial working memory operations. In an fMRI study (functional magnetic resonance imaging), we therefore examined the role of the hippocampus dur...

journal_title：Brain research

authors： Toepper M,Markowitsch HJ,Gebhardt H,Beblo T,Thomas C,Gallhofer B,Driessen M,Sammer G

更新日期：2010-10-01 00:00:00

abstract：:Quantitative morphological techniques have revealed several new aspects of the action of the Staggerer mutant gene. Staggerer is an autosomal recessive gene which causes ataxia and severe malformation of the cerebellar cortex in mice. The Purkinje cells of the cerebellar cortex are small, abnormal in morphology and re...

journal_title：Brain research

authors： Roffler-Tarlov S,Herrup K

更新日期：1981-06-29 00:00:00

abstract：:The distribution of NK(1) receptor immunoreactivity in the amygdaloid complex, induction of NK(1) receptor endocytosis in the amygdala following immobilisation stress, and the ability of pretreatment with the substance P antagonist L-760,735 or imipramine to block this response were examined in gerbils, a species with...

journal_title：Brain research

authors： Smith DW,Hewson L,Fuller P,Williams AR,Wheeldon A,Rupniak NM

更新日期：1999-11-27 00:00:00

abstract：:We studied the effects of transcranial magnetic stimulation (TMS) on muscle activation patterns and joint kinematics during oscillatory movements of a joint within a two-joint (elbow-wrist) synergy. Healthy young adults (N=8) performed cyclic movements in one of the joints while the other joint was or was not involved...

journal_title：Brain research

authors： Latash ML,Danion F,Bonnard M

更新日期：2003-01-31 00:00:00

abstract：:Experimental traumatic brain injury (TBI) is known to produce an acute increase in cerebral glucose utilization, followed rapidly by a generalized cerebral metabolic depression. The current studies determined effects of single or multiple treatments with sodium pyruvate (SP; 1000mg/kg, i.p.) or ethyl pyruvate (EP; 40m...

journal_title：Brain research

authors： Moro N,Ghavim SS,Harris NG,Hovda DA,Sutton RL

更新日期：2016-07-01 00:00:00

abstract：:Nodes of Ranvier in the central nervous system in mammals are characterized by the presence of perinodal astrocytic processes. This study examines the association between processes of radial glia and the axolemma at nodes of Ranvier in the spinal cord of the mature axolotl, an animal in which radial glia represent a l...

journal_title：Brain research

authors： Sims TJ,Gilmore SA,Waxman SG

更新日期：1991-05-17 00:00:00

abstract：:Intracerebroventricular (ICV) streptozotocin (STZ) treated rat has been described as a suitable model for sporadic Alzheimer's disease (AD). Central application of STZ has demonstrated behavioral and neurochemical features that resembled those found in human AD. Chronic treatments with antioxidants, acetylcholinestera...

journal_title：Brain research

authors： Ponce-Lopez T,Liy-Salmeron G,Hong E,Meneses A

更新日期：2011-12-02 00:00:00

abstract：:Traumatic brain injury (TBI) causes impairments of both motor and spatial memory performances. Research is only beginning to reveal the biochemical mechanism(s) underlying these deficits. It has been postulated that reactive oxygen species such as the superoxide and hydroxyl radicals, as well as the peroxynitrite anio...

journal_title：Brain research

authors： Long DA,Ghosh K,Moore AN,Dixon CE,Dash PK

更新日期：1996-04-22 00:00:00

abstract：:Immunocytochemistry and high-performance liquid chromatography with electrochemical detection (HPLC-ED) were used, more than 76 days after infraorbital nerve (ION) transection, to examine the distribution and density of serotonin-immunoreactive (5-HTIR) axons, as well as serotonin (5-HT) and 5-hydroxyindoleacetic acid...

journal_title：Brain research

authors： Klein BG,Blaker WD

更新日期：1990-12-17 00:00:00

abstract：:Certain developmental abnormalities have been associated with environmental exposure to lead and our previous studies have indicated that the endogenous opioid system is disrupted by this metal. In connection with this we report the ontogeny of proenkephalin products in the rat striatum determined by combined HPLC and...

journal_title：Brain research

authors： Bailey C,Kitchen I

更新日期：1985-09-01 00:00:00

abstract：:The understanding of sentences involves not only the retrieval of the meaning of single words, but the identification of the relation between a verb and its arguments. The way the brain manages to process word meaning and syntactic relations during language comprehension on-line still is a matter of debate. Here we re...

journal_title：Brain research

authors： Friederici AD,Weissenborn J

更新日期：2007-05-18 00:00:00

abstract：:The A-ring reduced metabolite of deoxycorticosterone, 3 alpha, 5 alpha-tetrahydrodeoxycorticosterone (THDOC) was recently shown to act at the gamma-aminobutyric acid receptor-chloride ion channel complex in rat brain. The behavioral profile of THDOC was investigated using two animal models of anxiety, the two-chambere...

journal_title：Brain research

authors： Crawley JN,Glowa JR,Majewska MD,Paul SM

更新日期：1986-11-29 00:00:00

abstract：:We have previously observed that chronic cocaine administration increases levels of adenylyl cyclase and cAMP-dependent protein kinase (PKA) in the nucleus accumbens (NAc). In the present work we directly examined the involvement of the cAMP system at the level of the NAc in cocaine-induced locomotor activity and sens...

journal_title：Brain research

authors： Miserendino MJ,Nestler EJ

更新日期：1995-03-20 00:00:00

abstract：:Activation of the immune system in response to either infection or lipopolysaccharide (LPS) produces neurophysiological, neuroendocrine and behavioral changes. Some of the physiological consequences of LPS are mediated by endogenous opioid peptides. The following studies were designed to characterize the effects of LP...

journal_title：Brain research

authors： Yirmiya R,Rosen H,Donchin O,Ovadia H

更新日期：1994-06-13 00:00:00

abstract：:The effects of midazolam, one of the most popular benzodiazepines, on synaptic transmissions were compared with intracellular recordings between CA1 pyramidal cells (CA1-PCs) and dentate gyrus granule cells (DG-GCs) in rat hippocampal slices. First, we studied the effects of midazolam on orthodromically evoked spikes,...

journal_title：Brain research

authors： Sato Y,Fujito Y,Aoki M

更新日期：1997-10-31 00:00:00

abstract：:In the present study we analyzed the effect of ascorbate (0.8 mM)/Fe2+ (2.5 microM)-induced membrane lipid peroxidation on the levels of intracellular free calcium,[Ca2+]i and on the possible mechanisms involved in the perturbation of intracellular calcium homeostasis during oxidative stress. For this purpose, the inf...

journal_title：Brain research

authors： Pereira C,Ferreira C,Carvalho C,Oliveira C

更新日期：1996-03-25 00:00:00

abstract：:This study attempted to ascertain whether heatstroke-induced ischemia is associated with augmented striatal glutamate release and can be attenuated by NMDA receptor antagonists. Mean arterial pressure (MAP), striatal cerebral blood flow (CBF), striatal glutamate release and striatal neuronal damage score were assessed...

journal_title：Brain research

authors： Yang YL,Pan WH,Chiu TH,Lin MT

更新日期：1998-06-08 00:00:00

abstract：:The effects of indomethacin (10 mg/kg) on the release of the transmitter amino acids, glutamate, aspartate, GABA, and of the purines, adenosine and inosine, from the cerebral cortex was studied in a four-vessel occlusion rat model of cerebral ischemia/reperfusion. In comparison with the control group, indomethacin sig...

journal_title：Brain research

authors： Phillis JW,Smith-Barbour M,Perkins LM,O'Regan MH

更新日期：1994-08-01 00:00:00

abstract：:ENT1 is an equilibrative nucleoside transporter that enables trans-membrane bi-directional diffusion of biologically active purines such as adenosine. In spinal cord dorsal horn and in sensory afferent neurons, adenosine acts as a neuromodulator with complex pro- and anti-nociceptive actions. Although uptake and relea...

journal_title：Brain research

authors： Governo RJ,Deuchars J,Baldwin SA,King AE

更新日期：2005-10-19 00:00:00

abstract：:It is well established that extracellular choline is transported into central cholinergic nerve terminals by 'high' and 'low' affinity processes to form the neurotransmitter acetylcholine (ACh). The intent of the present investigation was to ascertain whether extracellular acetate might also be transported into centra...

journal_title：Brain research

authors： Carroll PT

更新日期：1997-04-04 00:00:00

abstract：:Bilateral intraventricular injections of 6-hydroxydopamine depleted dopamine (DA) in striatal tissue of rats by 88%. Tail shock increased DA in striatal extracellular fluid of these rats from 10 to 17 pg/20 microliters as measured by microdialysis, values less than half those seen in normal striatum. The increase was ...

journal_title：Brain research

authors： Keefe KA,Stricker EM,Zigmond MJ,Abercrombie ED

更新日期：1990-09-17 00:00:00

abstract：:Our recent results showed that angiotensin II or III (AII, AIII) microinjected into the zona incerta (ZI) significantly increased water intake. The most effective doses of AII and AIII were also defined. The two neuropeptides had their effects differently on drinking via different receptors. AII bound to AT(1) that wa...

journal_title：Brain research

authors： Bagi EE,Fekete E,Bányai D,Lénárd L

更新日期：2004-03-26 00:00:00

abstract：:The effects of clonidine (CLO) and phentolamine (PHE) on the sleep-waking cycle in the cat treated with alpha-methyl-p-tyrosine (AMPT) were investigated with continuous 16--24 h polygraphic recordings. For the evaluation of possible cholinergic interactions in the paradoxical sleep (PS) increasing effect of AMPT, an a...

journal_title：Brain research

authors： Leppävuori A

更新日期：1980-07-07 00:00:00

abstract：:Cholecystokinins in rat cerebral cortex were studied by radioimmunoassay using an antiserum specific for the COOH-terminus of CCK8. Total concentrations of immunoreactive CCK in cortex were 3-4 fold higher than in jejunum. Rat cerebral CCK was purified by immuno-affinity adsorption to the IgG fraction of CCK antisera ...

journal_title：Brain research

authors： Dockray GJ

更新日期：1980-04-21 00:00:00

abstract：:Toxoplasma gondii can cause parasitic encephalitis, a life-threatening infection that predominately occurs in immunocompromised individuals. T. gondii has the ability to invade the brain, but the mechanisms by which this parasite crosses the blood-brain-barrier (BBB) remain incompletely understood. The present study r...

journal_title：Brain research

authors： Harun MSR,Marsh V,Elsaied NA,Webb KF,Elsheikha HM

更新日期：2020-11-01 00:00:00

abstract：:The expression of phosphorylated extracellular signal-regulated kinase 1/2 (pERK 1/2) was evaluated in the vestibular nuclei (VN) of rats following unilateral labyrinthectomy (UL). Immunohistochemistry revealed a significant asymmetrical increase in pERK 1/2 expression in the VN, 5 min after UL, after which pERK 1/2 i...

journal_title：Brain research

authors： Kim MS,Choi MA,Choi DO,Lee MY,Kim KY,Rhee JK,Jin YZ,Park BR

更新日期：2004-06-18 00:00:00