Evidence to suggest that extracellular acetate is accumulated by rat hippocampal cholinergic nerve terminals for acetylcholine formation and release.

abstract：:The developmental control of neuroblast proliferation is absolutely required for the assembly and function of the central nervous system. A lethal mutation in trol results in the failure of quiescent neuroblasts to begin division at the appropriate time. I have established a culture system in which quiescent neuroblas...

journal_title：Brain research

authors： Datta S

更新日期：1999-02-06 00:00:00

abstract：:Effects of hypothalamic stimulation (HS) were studied in intracellular recordings obtained from 125 neurons of the motor cortex (MC). HS that was effective in reinforcing bar-press behavior, i.e. satisfactory for intracranial self-stimulation (ICSS), evoked short-latency (less than 3 ms) activation of these cortical n...

journal_title：Brain research

authors： Aou S,Oomura Y,Woody CD,Nishino H

更新日期：1988-01-26 00:00:00

abstract：:The structure of the plasma membrane of two neuronal cell types was quantitatively assessed in freeze-fracture replicas of rat cerebellar cortex from 2 to 73 postnatal days. The measurement of the number and size of intramembrane particles (IMP) in different regions of the Purkinje cells and of the granule cell showed...

journal_title：Brain research

authors： Garcia-Segura LM,Perrelet A

更新日期：1981-03-09 00:00:00

abstract：:In this study, we observed the chronological alterations of neurofilament 150 (NF-150) immunoreactivity in the gerbil hippocampus and dentate gyrus after 5 min transient forebrain ischemia. NF-150 immunoreactivity in the sham-operated group was mainly detected in mossy fibers and in the hilar region of the dentate gyr...

journal_title：Brain research

authors： Hwang IK,Do SG,Yoo KY,Kim DS,Cho JH,Kwon YG,Lee JY,Oh YS,Kang TC,Won MH

更新日期：2004-07-30 00:00:00

abstract：:Transport of fragmented DNA in apical dendrites of the CA1 pyramidal neurons of gerbil hippocampus is observed in the apoptotic process following transient forebrain ischemia. The time-course of specific DNA fragmentation was examined after the ischemic insult by in situ nick-end-labeling method and fluorescence detec...

journal_title：Brain research

authors： Hara A,Niwa M,Iwai T,Nakashima M,Yano H,Uematsu T,Yoshimi N,Mori H

更新日期：1998-09-28 00:00:00

abstract：:Influence of dopamine agonists, methamphetamine (MAT, 1 mg/kg, i.p.) and apomorphine (APO, 1 mg/kg, i.p.), on the effects of amygdaloid lesions on thresholds for the defensive attack behavior elicited by electrical stimulation of the ventromedial hypothalamic nucleus was studied in cats. The thresholds were measured i...

journal_title：Brain research

authors： Maeda H,Maki S

更新日期：1986-01-15 00:00:00

abstract：:This study evaluated the hypothesis that the dorsal motor nucleus (DMN) of the brainstem may mediate the ulcerogenic and acid-stimulatory effects of thyrotropin-releasing hormone (TRH) in rats. To accomplish this, intra-DMN microinjections of TRH (50 and 500 ng) were performed and their effects on acid secretion and g...

journal_title：Brain research

authors： Hernandez DE,Emerick SG

更新日期：1988-08-30 00:00:00

abstract：:Microinjection of bicuculline (Bic) into the unilateral putamen (Put) of the cat resulted in periodic occurrence of contralateral movement of the head (dystonia). Corresponding to this dystonic movement, repetitive spikes of the field potential occurring in the Put of the injected side and strong inhibition of the ext...

journal_title：Brain research

authors： Yamada H,Fujimoto K,Yoshida M

更新日期：1995-04-24 00:00:00

abstract：:The ability of beta-phenylethylamine (PEA) to reverse (1) chlorpromazine-induced activation of striatal tyrosine hydroxylase, and (2) catalepsy produced by chlorpromazine, was examined. PEA, in a dose of 75 mg/kg, caused approximately 50% reduction in the degree of tyrosine hydroxylase stimulation produced by 20 mg/kg...

journal_title：Brain research

authors： Stoff DM,Gale K

更新日期：1981-05-04 00:00:00

abstract：:The pretectal olivary nucleus of the squirrel monkey was examined in both normal and autoradiographic material. In the Nissl- and fiber-stained tissue the nucleus appears as a laminated structure. The distribution of retinal terminals within the nucleus was examined by the autoradiographic tracing method. These data r...

journal_title：Brain research

authors： Weber JT,Young R,Hutchins B

更新日期：1981-11-09 00:00:00

abstract：:Tinnitus, the perception of a phantom sound, is a common consequence of damage to the auditory periphery. A major goal of tinnitus research is to find the loci of the neural changes that underlie the disorder. Crucial to this endeavor has been the development of an animal behavioral model of tinnitus, so that neural c...

journal_title：Brain research

authors： Baizer JS,Manohar S,Paolone NA,Weinstock N,Salvi RJ

更新日期：2012-11-16 00:00:00

abstract：:Alterations in protein phosphorylation may be important in the pathogenesis of Alzheimer's disease and recent observations suggest that a subset of protein kinase pathways may be selectively altered. Calcium/calmodulin-dependent protein kinase II CaM kinase II) is the most abundant protein kinase in the brain and is b...

journal_title：Brain research

authors： Simonian NA,Elvhage T,Czernik AJ,Greengard P,Hyman BT

更新日期：1994-09-19 00:00:00

abstract：:Based on electrophysiological data showing that repeated cocaine administration produces persistent enhancement of D1 dopamine (DA) receptor-mediated responses in nucleus accumbens (NAc), we investigated whether changes in neurochemical properties of these receptors resulted when rats were injected with cocaine (15 mg...

journal_title：Brain research

authors： Mayfield RD,Larson G,Zahniser NR

更新日期：1992-02-28 00:00:00

abstract：:Neurokinins, such as substance P (SP), modulate the reflex regulation of cardiovascular and respiratory function in the CNS, particularly in the nucleus tractus solitarius (NTS). There is considerable evidence of the action of SP in the NTS, but the precise effects have not yet been determined. Voltage-dependent Ca2+ ...

journal_title：Brain research

authors： Endoh T

更新日期：2006-09-19 00:00:00

abstract：:The localization of a GTP-binding protein (G(o)) in the cerebellar and cerebral cortex and hippocampus of the normal and reeler mutant mouse was immunohistochemically examined using affinity-purified antibody raised against the alpha subunit of G(o). Although the general distribution pattern of G(o)-immunoreactive pro...

journal_title：Brain research

authors： Terashima T,Katada T,Ichikawa R,Ui M,Inoue Y

更新日期：1993-01-22 00:00:00

abstract：:Previous studies using the spin trapping agent N-tert-butyl-alpha-phenylnitrone (PBN) and the antioxidant vitamin E established the involvement of free radicals in kainic acid (KA)-induced neurotoxicity. In the present study, we examined the effects of the neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazol...

journal_title：Brain research

authors： Gupta RC,Dettbarn WD

更新日期：2003-08-15 00:00:00

abstract：:Diabetes mellitus can lead to functional and structural deficits in both the peripheral and central nervous system. The pathogenesis of these deficits is multifactorial, probably involving, among others, microvascular dysfunction and alterations in intracellular calcium homeostasis. The present study examined the effe...

journal_title：Brain research

authors： Biessels GJ,ter Laak MP,Kamal A,Gispen WH

更新日期：2005-02-21 00:00:00

abstract：:Despite insights into an increasingly significant role for delta opioid receptors in thermoregulation, it is unclear whether delta receptors located in the brain or periphery play the more critical role in body temperature regulation. Moreover, it is not entirely clear which delta receptor phenotype, delta1 or delta2,...

journal_title：Brain research

authors： Rawls SM,Hewson JM,Inan S,Cowan A

更新日期：2005-07-05 00:00:00

abstract：:Luteinizing hormone (LH) secretion during the reproductive cycle and in ovariectomized (OVX) rats is pulsatile and this pattern of secretion is determined by intermittent discharges of LH-releasing hormone (LHRH) into the hypophysial portal vessels. LHRH secretion is probably controlled by prior pulsatile norepinephri...

journal_title：Brain research

authors： Anselmo-Franci JA,Rocha-Barros VM,Franci CR,McCann SM

更新日期：1999-06-26 00:00:00

abstract：:Excitotoxic neuronal death underlies many neurodegenerative disorders. Because cannabinoid receptor agonists act presynaptically to inhibit glutamate release, we examined the effects of Win 55212-2, a full agonist at CB(1) receptors, and Delta(9)-tetrahydrocannabinol (THC), a partial agonist, on the survival of neuron...

journal_title：Brain research

authors： Gilbert GL,Kim HJ,Waataja JJ,Thayer SA

更新日期：2007-01-12 00:00:00

abstract：:A classification of the parietal corticofugal neurons was performed in cats under Nembutal anesthesia. Eighty-eight neurons were identified with antidromic activation by the pontine stimulation. Thirteen neurons were furthermore identified with intracellular HRP staining. In these neurons, we found the close correlati...

journal_title：Brain research

authors： Samejima A,Yamamoto T,Ito J,Oka H

更新日期：1985-11-11 00:00:00

abstract：:Mechanical hyperalgesia is an early symptom of diabetic neuropathy. To evaluate the mechanisms underlying this symptom, it was studied and compared in rat models of systemic and local hyperglycemia. Systemic hyperglycemia was induced by a single injection of streptozotocin (STZ, 50 mg/kg). Local hyperglycemia either i...

journal_title：Brain research

authors： Dobretsov M,Hastings SL,Romanovsky D,Stimers JR,Zhang JM

更新日期：2003-01-17 00:00:00

abstract：:Endogenous hyperprolactinaemia was induced in intact male rats by transplantation of pituitaries under the kidney capsule. Five days later the utilization of noradrenaline (NA) and dopamine (DA) in individual brain nuclei and changes of plasma prolaction (PRL) were measured. Inhibition of catecholamine synthesis by al...

journal_title：Brain research

authors： Kovács GL,Drago F,Acsai L,Tihanyi A,Scapagnini U,Telegdy G

更新日期：1984-12-17 00:00:00

abstract：:Newborn rats were given saline or cholecystokinin8 (CCK8) (5 micrograms/kg, twice daily) i.p. for 3 weeks. On day 21, effects on brain development were assessed. CCK-like immunoreactivity was measured in 7 brain regions; a small (12-18%) but significant decrease in endogenous levels of this peptide was detected in cer...

journal_title：Brain research

authors： Johnson FE,Hudd C,LaRegina MC,Beinfeld MC,Tolbert DL,Spain JW,Szucs M,Coscia CJ

更新日期：1987-03-01 00:00:00

abstract：:Rarely do we encounter a single odorant in our environment. Perception of odours, therefore, usually depends on the reception and neural processing of many components. However, little is known about how and where odour mixtures are processed. Evidence is presented here that suppression of one odour by another, a commo...

journal_title：Brain research

authors： Bell GA,Laing DG,Panhuber H

更新日期：1987-11-17 00:00:00

abstract：:Retrograde transport of horseradish peroxidase (HRP) was used to identify supraependymal neurons projecting to the pituitary gland in the hamster. Supraependymal neurons overlying the median eminence were labeled by HRP injections into the neural and intermediate lobes of the pituitary gland; no neurons were labeled f...

journal_title：Brain research

authors： Michael DB,Hazlett JC,Mitchell JA

更新日期：1989-01-30 00:00:00

abstract：:Exposure of newborn rats to antiepileptics such as barbiturates has long-lasting detrimental effects on the hippocampus and hippocampus-dependent behavior. However, the long-term consequences of neonatal administration with barbiturates on the hippocampal synaptic plasticity remain unresolved. In this study, we invest...

journal_title：Brain research

authors： Tachibana K,Hashimoto T,Kato R,Tsuruga K,Ito R,Morimoto Y

更新日期：2011-05-04 00:00:00

abstract：:Stimulation of spinal serotonin (5-HT)(2A/2C) receptors has previously been reported to lead to either a pro-nociceptive or an anti-nociceptive response. Behavioral data have indicated that the pro-nociceptive effect is related to the release of substance P (SP). The aim of this in vivo microdialysis study was to inve...

journal_title：Brain research

authors： Kjørsvik Bertelsen A,Warsame Afrah A,Gustafsson H,Tjølsen A,Hole K,Stiller CO

更新日期：2003-10-10 00:00:00

abstract：:A positive association between cardiorespiratory fitness (CRF) and white matter integrity has been consistently reported in older adults. However, it is unknown whether this association exists in adults over 80 with a range of chronic disease conditions and low physical activity participation, which can influence both...

journal_title：Brain research

authors： Tian Q,Simonsick EM,Erickson KI,Aizenstein HJ,Glynn NW,Boudreau RM,Newman AB,Kritchevsky SB,Yaffe K,Harris T,Rosano C,Health ABC study.

更新日期：2014-11-07 00:00:00

abstract：:Glioblastoma stem cells (GSCs) are thought to contribute to the diffuse invasiveness of malignant gliomas. Emerging evidence supports a role for a disintegrin and metalloproteinase 17 (ADAM17) in proteolytic ectodomain shedding of several EGFR-binding ligands, which subsequently activate PI3K/AKT and MEK/ERK pathways ...

journal_title：Brain research

authors： Chen X,Chen L,Chen J,Hu W,Gao H,Xie B,Wang X,Yin Z,Li S,Wang X

更新日期：2013-11-13 00:00:00