Cocaine-induced behavioral sensitization and D1 dopamine receptor function in rat nucleus accumbens and striatum.

abstract：:2-Deoxy-d-glucose (2DG) is a glucose analogue that inhibits intracellular utilization of glucose and produces a characteristic behavioral response known as glucoprivic feeding. The area postrema (AP) is a caudal hindbrain structure shown previously to be involved in 2DG-induced glucoprivic feeding. In addition, periph...

journal_title：Brain research

authors： Edmonds BK,Edwards GL

更新日期：1998-08-10 00:00:00

abstract：:Cultures of neonatal mouse cortical astrocytes synthesized NGF mRNA and released immunoreactive NGF (ir-NGF) into the culture medium. Addition of 10 microM guanosine or GTP to the cultures increased ir-NGF release by 6 and 2 fold, respectively, after 24 h, and increased NGF mRNA 6 fold after 4 h and 2-3 fold after 24 ...

journal_title：Brain research

authors： Middlemiss PJ,Gysbers JW,Rathbone MP

更新日期：1995-04-17 00:00:00

abstract：:Aluminum (Al), an important neurotoxin, contributes to a variety of cognitive dysfunction and mental diseases. Previous studies have demonstrated that Al impairs hippocampal long-term potentiation (LTP) in vitro and in vivo. In the present study, both LTP and LTD (long-term depression) were recorded in the same animal...

journal_title：Brain research

authors： Wang M,Chen JT,Ruan DY,Xu YZ

更新日期：2001-04-27 00:00:00

abstract：:Initial studies found glutamate injury to murine spinal cultures (14-17 days in vitro) to reflect contributions of both NMDA and AMPA/kainate receptors. Subsequent experiments found the spinal cultures to be more sensitive than cortical cultures to injury from prolonged low level kainate exposures, and, unlike cortica...

journal_title：Brain research

authors： Yin HZ,Park DD,Lindsay AD,Weiss JH

更新日期：1995-08-21 00:00:00

abstract：:Recent experimental data have shown that hyperbaric oxygen therapy (HBOT) was associated increased Bcl-2 expression at the injury site that correlated with reduced apoptosis. We hypothesized that HBOT mediated enhancement of Bcl-2 expression and increased intracellular oxygen bio-availability may both contribute to pr...

journal_title：Brain research

authors： Palzur E,Zaaroor M,Vlodavsky E,Milman F,Soustiel JF

更新日期：2008-07-24 00:00:00

abstract：:A major effect of volatile anesthetics is to reduce excitatory synaptic transmission. In the present study the stimulated release of glutamate under the influence of increasing concentrations of isoflurane was studied in vitro by utilizing hippocampal slices from Wistar rats. Ca(2+)-dependent release was calculated by...

journal_title：Brain research

authors： Larsen M,Grøndahl TO,Haugstad TS,Langmoen IA

更新日期：1994-11-14 00:00:00

abstract：:The effect of hypoxia on the structure and function of the synaptosomal membranes and myelin fraction (glial cells, neuronal cells bodies and axonal membranes) was investigated by measuring Na+,K(+)-ATPase activity and levels of lipid peroxidation products in cerebral cortical synaptosomal membranes and myelin fractio...

journal_title：Brain research

authors： Razdan B,Marro PJ,Tammela O,Goel R,Mishra OP,Delivoria-Papadopoulos M

更新日期：1993-01-15 00:00:00

abstract：:The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was studied in male hooded rats. Repeated kindling stimulations were delivered twice or three times daily until either 300 stimuli had been delivered or generalized convulsions had been observed to...

journal_title：Brain research

authors： Milgram NW,Michael M,Cammisuli S,Head E,Ferbinteanu J,Reid C,Murphy MP,Racine R

更新日期：1995-01-23 00:00:00

abstract：:Previous research with deafferented subjects suggests that efference copy can be used to update limb position. However, the contributions of efference copy to limb localization are currently unclear. We examined the performance of JDY, a woman with severe, longstanding proprioceptive deficits from a sensory peripheral...

journal_title：Brain research

authors： Medina J,Jax SA,Brown MJ,Coslett HB

更新日期：2010-10-08 00:00:00

abstract：:Rabbits passively oscillated in the horizontal plane with a free hand tended to stabilize their head in space (re: earth-fixed surroundings) by moving the head on the trunk (neck angular deviation, NAD) opposite the passively imposed body rotation. The gain (NAD/body rotation) of head stabilization varied from 0.0 to ...

journal_title：Brain research

authors： Fuller JH

更新日期：1981-02-02 00:00:00

abstract：:In view of the use of synthetic propentofylline (PPF) as a protective agent in brain ischemia, its possible side effects on vision capacities have been explored by electroretinography in comparative experiments with theophylline. We used eyecup preparations of small-spotted dogfish sharks and of European eels, particu...

journal_title：Brain research

authors： Andjus RK,Konjević D,Damjanović I,Gacić Z

更新日期：2000-06-23 00:00:00

abstract：:In normal adult rats, intense immunostaining for the 75 kDa low-affinity receptor for nerve growth factor and other neurotrophins (p75NGFR) is concentrated in the middle region of the cuneate nucleus (CN), distributed in a blotchy pattern similar to that of cytochrome oxidase (CO) activity. In the adult rats, partial ...

journal_title：Brain research

authors： Foschini DR,Egger MD,Crockett DP

更新日期：1994-05-16 00:00:00

abstract：:The trisomy-16 mouse is considered to be a model of human trisomy-21 (Down syndrome). We have examined the electrical membrane properties of cultured dorsal root ganglion (DRG) neurons from normal and trisomy-16 fetuses. Trisomy-16 neurons had significantly accelerated rates of action potential depolarization and repo...

journal_title：Brain research

authors： Ault B,Caviedes P,Rapoport SI

更新日期：1989-04-17 00:00:00

abstract：:Somatostatin-like immunoreactivity (Som-LI) and glycine high-affinity uptake have been characterized in the Rana pipiens retina. These labels are found in both the outer and inner plexiform layers (OPL and IPL), suggesting that interplexiform cells (IPCs) contain both Som and glycine in this retina. In double-label ex...

journal_title：Brain research

authors： Smiley JF,Basinger SF

更新日期：1989-08-21 00:00:00

abstract：:A member of the tumor necrosis factor receptor superfamily (TNFRSF), TROY/TNFRSF19/TAJ, is highly expressed in the brain of adult mice. Northern blot analysis using mRNA taken from regions of the adult CNS showed the expression of TROY in all regions examined, including the olfactory bulb, cerebral cortex, striatum, a...

journal_title：Brain research

authors： Hisaoka T,Morikawa Y,Senba E

更新日期：2006-09-19 00:00:00

abstract：:Immunohistochemical and retrograde tracing techniques were combined to demonstrate the occurrence of displaced ganglion cells (DGCs) exhibiting substance P-like immunoreactivity (SP-LI) in the pigeon retina. Following injections of rhodamine-labeled latex microspheres into the nucleus of the basal optic root (accessor...

journal_title：Brain research

authors： Britto LR,Hamassaki DE

更新日期：1991-04-12 00:00:00

abstract：:Memory and perception are two tightly interrelated cognitive processes, but the neural level of their interaction remains a matter of debate. Proponents of a late interaction emphasize feedback memory effects on visual processing, whereas others suggest that feed forward processing is affected by memory. In the visual...

journal_title：Brain research

authors： Chaumon M,Hasboun D,Baulac M,Adam C,Tallon-Baudry C

更新日期：2009-08-18 00:00:00

abstract：:Parkinson's disease (PD) is characterized by progressive degeneration of nigrostriatal dopaminergic neurons. Several factors such as inhibition of the mitochondrial respiration, generation of hydroxyl radicals and reduced free radical defense mechanisms causing oxidative stress, have been postulated to contribute to t...

journal_title：Brain research

authors： Muralikrishnan D,Ebadi M

更新日期：2001-02-23 00:00:00

abstract：:Exposure of newborn rats to antiepileptics such as barbiturates has long-lasting detrimental effects on the hippocampus and hippocampus-dependent behavior. However, the long-term consequences of neonatal administration with barbiturates on the hippocampal synaptic plasticity remain unresolved. In this study, we invest...

journal_title：Brain research

authors： Tachibana K,Hashimoto T,Kato R,Tsuruga K,Ito R,Morimoto Y

更新日期：2011-05-04 00:00:00

abstract：:This study investigated the effects of antidromically conducted nerve impulses on the transmission of orthodromic volleys in primary afferents of the hindlimb in decerebrated paralyzed cats. Two protocols were used: (A) Single skin and muscle afferents (N=20) isolated from the distal part of cut dorsal rootlets (L7-S1...

journal_title：Brain research

authors： Gossard JP,Bouyer L,Rossignol S

更新日期：1999-04-17 00:00:00

abstract：:Electroconvulsive therapy (ECT) is widely used as a treatment for drug-resistant depression. The animal analogue of ECT is electroconvulsive shock (ECS) seizures. We have recently shown that repeated ECS seizures cause a long-lasting, perhaps permanent, enhancement in entorhinal-dentate evoked potentials in the rat. O...

journal_title：Brain research

authors： Gombos Z,Mendonça A,Racine RJ,Cottrell GA,Burnham WM

更新日期：1997-08-22 00:00:00

abstract：:The development of spontaneous activity in response to morphine administration was studied at different postnatal ages in C57BL/6 mice. Morphine induced hyperactivity at all ages except in 3-week-old mice, in which a catatonic effect is evident. The results indicate that the neurophysiological and inhibitory systems r...

journal_title：Brain research

authors： Filibeck U,Castellano C,Oliverio A

更新日期：1981-11-01 00:00:00

abstract：:The characteristics of the spontaneous discharges of populations of single neurons in the neocortex and thalamus of rats reared under chronic protein malnutrition (8% casein) or a normal diet (25% casein) were evaluated. Results from 700 neurons showed the malnourished rats had fewer fast firing cells, an overall lowe...

journal_title：Brain research

authors： Stern WC,Pugh WW,Johnson A,Morgane PJ

更新日期：1983-07-01 00:00:00

abstract：:Aluminum (Al) is among the most abundant elements on earth, it has been associated with the etiology of Alzheimer's disease. In the present study, AlCl(3) was administered with the dose of 10, 50 or 300 mg/kg b.wt/day through diet for 100 days. On day 101, overnight-fasted animals were sacrificed, the whole brains wer...

journal_title：Brain research

authors： Rui D,Yongjian Y

更新日期：2010-04-09 00:00:00

abstract：:It has been demonstrated that castration alters the functioning of the olfactory bulb (OB)-norepinephrine (NE) system. In the present experiment, we examined one of the mechanisms by which castration modulates the OB-NE system by comparing NE uptake activity between intact and castrated male rats as studied using an i...

journal_title：Brain research

authors： Shang Y,Dluzen DE

更新日期：1998-01-01 00:00:00

abstract：:Reports suggested that the predominant site of action for the antihypertensive effects of clonidine is the rostral ventrolateral medulla (RVL), the presumed tonic vasomotor center. This study examined whether clonidine directly interacts with nerve terminal alpha 2-adrenergic receptors in the RVL to inhibit the releas...

journal_title：Brain research

authors： Tingley FD 3rd,Arnerić SP

更新日期：1990-12-24 00:00:00

abstract：:The present study examined if olfactory bulbectomy (OBX) altered defensive behaviors on the elevated plus-maze and the open-field differently in male and female rats. Similar increases in defensive behaviors in male and female rats were observed in both tests following OBX. No significant correlations were detected be...

journal_title：Brain research

authors： Stock HS,Hand GA,Ford K,Wilson MA

更新日期：2001-06-08 00:00:00

abstract：:Estrogen receptor α (ERα) isoforms with complex types of alternative splicing are naturally present in the human brain and may affect canonical receptor signaling. In the present study we investigated transcriptional activity of common ERα splice variants from this group with different molecular defects: MB1 (intron r...

journal_title：Brain research

authors： Ishunina TA,Sluiter AA,Swaab DF,Verwer RW

更新日期：2013-03-15 00:00:00

abstract：:The prostacyclin (PGI2) formation in cerebral vessels, as reflected by the difference in concentration of internal carotid arterial and internal jugular venous radioimmunoassayed 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), was determined under normocapnic and hypercapnic conditions in 5 patients with mild cereb...

journal_title：Brain research

authors： Uyama O,Nagatsuka K,Fukunaga R,Kusunoki M,Takano T,Yoneda S,Kimura K,Abe H

更新日期：1983-01-24 00:00:00

abstract：:The present study combined masked priming with electrophysiological recordings to investigate orthographic priming effects with nonword targets. Targets were pronounceable nonwords (e.g., STRENG) or consonant strings (e.g., STRBNG), that both differed from a real word by a single letter substitution (STRONG). Targets ...

journal_title：Brain research

authors： Massol S,Midgley KJ,Holcomb PJ,Grainger J

更新日期：2011-04-22 00:00:00