Extracellular guanosine and guanosine-5'-triphosphate increase: NGF synthesis and release from cultured mouse neopallial astrocytes.

abstract：:The recruitment of performance control was recently explained in terms of the detection of response conflict. One recent hypothesis claims that the degree of response conflict is reflected in an electroencephalographical component, the Error Negativity (Ne). Indeed, in the framework of simulations, variations of the N...

journal_title：Brain research

authors： Carbonnell L,Falkenstein M

更新日期：2006-06-20 00:00:00

abstract：:The effects of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS), a synthetic precursor of norepinephrine (NE), on the long-term potentiation (LTP) in the hippocampal mossy fiber-CA3 system was examined in urethane-anesthetized rats, the objective being to determine whether or not this drug acts as NE on the LTP. L-thr...

journal_title：Brain research

authors： Sakai N,Sasa M,Ishihara K,Komure O,Tanaka C,Takaori S

更新日期：1991-12-20 00:00:00

abstract：:Fetal mouse dorsal root ganglion (DRG) neurons were maintained in primary dissociated cell culture for periods of 7 days to 3 months. Intracellular recordings from these cells revealed the presence of spontaneous subthreshold potentials in 101/177 neurons studied. When measured at the resting membrane potential, these...

journal_title：Brain research

authors： Mathers DA,Barker JL

更新日期：1984-02-13 00:00:00

abstract：:Recent developments in the understanding of the neurophysiological mechanisms underlying electroencephalographic (EEG) slow waves and sleep spindles imply an inverse relationship between these two EEG activities. The interrelationship between slow wave activity (0.75-4.5 Hz) and sleep-spindle activity (12-15 Hz) in el...

journal_title：Brain research

authors： Dijk DJ,Hayes B,Czeisler CA

更新日期：1993-10-29 00:00:00

abstract：:The effect of aging on delta opioid receptors was examined in the brains of guinea pigs aged 1, 6, 24 and 36 months. Quantitative autoradiography was used to monitor the concentrations of delta receptors in various anatomical regions at five rostro-caudal levels. delta opioid receptor populations were found to be rema...

journal_title：Brain research

authors： Hiller JM,Fan LQ,Simon EJ

更新日期：1993-06-18 00:00:00

abstract：:Rodent models of focal and global ischemia were used to examine caspase activation. Several readouts were employed on identical tissue to provide correlative measurement of caspase induction, activation and enzymatic activity. In a rat focal ischemia model, caspase-3 enzymatic activity, as recorded by DEVD-AMC cleavag...

journal_title：Brain research

authors： Cho S,Liu D,Gonzales C,Zaleska MM,Wood A

更新日期：2003-08-29 00:00:00

abstract：:Pretreatment with scopolamine, 3 mg/kg, prevented the acquisition of a passive avoidance task in rats. These amnesic effects of scopolamine could largely be overcome by treatment with 100 mg/kg of the nootropic drug piracetam. In order to identify the brain structures involved, the effects of these drugs on regional e...

journal_title：Brain research

authors： Piercey MF,Vogelsang GD,Franklin SR,Tang AH

更新日期：1987-10-20 00:00:00

abstract：:Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of membrane phospholipids and has been suggested as an effector in the receptor-mediated release of arachidonic acid in signal transduction. The potential role of cPLA2 as an effector in muscarinic acetylcholi...

journal_title：Brain research

authors： Lautens LL,Chiou XG,Sharp JD,Young WS 3rd,Sprague DL,Ross LS,Felder CC

更新日期：1998-10-26 00:00:00

abstract：:The implantation of dopamine-rich mesencephalic grafts into the 6-hydroxydopamine (6-OHDA)-lesioned neostriatum of rats was accompanied by marked hyperinnervation by serotonin (5-HT) fibers. The purpose of this study was to examine the possibility that the graft-derived 5-HT hyperinnervation is governed by target-rela...

journal_title：Brain research

authors： Takeuchi Y,Sawada T,Blunt S,Jenner P,Marsden CD

更新日期：1992-10-02 00:00:00

abstract：:Neural plasticity of afferent pain pathways that is induced by prolonged or repeated noxious stimuli may contribute to activate intrinsic inhibitory mechanisms in CNS. In order to clarify the role of the monoaminergic descending inhibitory system in acute nociception and inflammatory pain, we examined if this inhibito...

journal_title：Brain research

authors： Omote K,Kawamata T,Kawamata M,Namiki A

更新日期：1998-12-14 00:00:00

abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...

journal_title：Brain research

authors： Zhao XC,Zhang LM,Li Q,Tong DY,Fan LC,An P,Wu XY,Chen WM,Zhao P,Wang J

更新日期：2013-11-06 00:00:00

abstract：:Problems in interpretation of autoradiograms generated by ligand binding in brain tissue may be caused by two types of technical limitations: the differential absorption of 3H-generated emissions within the tissue (differential quenching) and the reduced resolution when 125I and 14C are used as isotopes. In the course...

journal_title：Brain research

authors： Lidow MS,Goldman-Rakic PS,Rakic P,Gallager DW

更新日期：1988-08-30 00:00:00

abstract：:Monoclonal antibody N210 (mabN210) recognizes the 210 kdalton neurofilament protein in mammals and gives characteristic immunocytochemical staining of neurofilament-rich processes. For example, in the cerebellum it recognizes myelinated axons and the calyx formed by basket cell axon collaterals. The distribution of ma...

journal_title：Brain research

authors： Maler L,Leclerc N,Hawkes R

更新日期：1986-07-23 00:00:00

abstract：:Recently, this laboratory provided evidence that interleukin-1beta (IL-1beta), an immune and brain-derived cytokine, microinjected into the medial hypothalamus, potentiates defensive rage behavior in the cat elicited from the midbrain periaqueductal gray (PAG), and that such effects are blocked by a 5-HT2 receptor ant...

journal_title：Brain research

authors： Hassanain M,Bhatt S,Zalcman S,Siegel A

更新日期：2005-06-28 00:00:00

abstract：:High-intensity stimulation of the supraorbital region elicits, together with a blink reflex, a reflex inhibition of the jaw-closing muscles in normal man. The response differs from the well known inhibition obtained by intra- and perioral stimulation in two main features. Firstly, it consists of a single late silent p...

journal_title：Brain research

authors： Cruccu G,Agostino R,Lahuerta J,Manfredi M

更新日期：1986-04-23 00:00:00

abstract：:Histone deacetylase 1 (HDAC1) plays a crucial role in cancer progression and development. This enzyme has been confirmed to be a key regulator of tumor biology functions, such as tumor cell proliferation, migration and invasion. However, HDAC1 expression in glioma remains controversial, and its specific function and m...

journal_title：Brain research

authors： Li S,Chen X,Mao L,Zahid KR,Wen J,Zhang L,Zhang M,Duan J,Duan J,Yin X,Wang Y,Zhao L,Tang X,Wang X,Xu G

更新日期：2018-08-01 00:00:00

abstract：:Source memory for the speaker's voice (male or female) was investigated when semantic knowledge (gender stereotypes) could and could not inform the episodic source judgment while event-related potentials (ERPs) were recorded. Source accuracy was greater and response times were faster when stereotypes could predict the...

journal_title：Brain research

authors： Leynes PA,Crawford JT,Radebaugh AM,Taranto E

更新日期：2013-01-23 00:00:00

abstract：:The ionic basis of norepinephrine (NE) action was studied with intracellular recording techniques in the rat hippocampal slice. Topical application of NE caused, in CA1 neurons, a 3-4 mV hyperpolarization associated with a 10-20% decrease in input resistance. This effect was accompanied by a decrease in spontaneous ac...

journal_title：Brain research

authors： Segal M

更新日期：1981-02-09 00:00:00

abstract：:Humans share the common intuition of a self that has access to an inner 'theater of mind' (Baars, 2003). The problem is how this internal theater is formed. Moving from Cook's view (Cook, 2008), we propose that the 'sentience' present in single excitable cells is integrated into units of neurons and glial cells transi...

journal_title：Brain research

authors： Agnati LF,Guidolin D,Cortelli P,Genedani S,Cela-Conde C,Fuxe K

更新日期：2012-10-02 00:00:00

abstract：:Previous research has demonstrated that cross-language activation is present even when proficient bilinguals perform a task only in one language. The present study investigated the time-course of cross-language activation during word production in a second language (L2) by using a picture-word interference paradigm wi...

journal_title：Brain research

authors： Hoshino N,Thierry G

更新日期：2011-01-31 00:00:00

abstract：:Noxious heat applied to the footpad evokes the expression of fos protein-like immunoreactivity in the rat spinal cord lumbar dorsal horn. Electrical stimulation in the medullary nucleus raphe magnus (NRM) while not evoking fos-like immunoreactivity itself, reduced significantly the number of neurons (to 50% of control...

journal_title：Brain research

authors： Jones SL,Light AR

更新日期：1990-10-22 00:00:00

abstract：:Two monkeys were trained to perform 3 kinds of spatial tasks (right-left DR, up-down DR, and conditional position discrimination with delay). In the conditional position task, the animal was required to respond to the right (left) choice key when the cue had been presented on the upper (lower) position. Single unit ac...

journal_title：Brain research

authors： Niki H,Watanabe M

更新日期：1976-03-19 00:00:00

abstract：:Anisomycin is both a well-established protein synthesis inhibitor and a potent activator of the p38/JNK MAPK pathway. It has been used to block the late phase of long-term potentiation (LTP) and long-term depression (LTD) in hippocampus. In this study, we have found that anisomycin produces a time-dependent decline in...

journal_title：Brain research

authors： Xiong W,Kojic LZ,Zhang L,Prasad SS,Douglas R,Wang Y,Cynader MS

更新日期：2006-04-26 00:00:00

abstract：:The Timm and selenium staining techniques, based on silver amplification of endogenous zinc, produce an electron-dense precipitate in boutons. The staining characteristics of the two methods were compared by examining two allocortical regions, prepiriform cortex and entorhinal cortex, in the brain of the European hedg...

journal_title：Brain research

authors： Schwerdtfeger WK,Danscher G,Geiger H

更新日期：1985-11-25 00:00:00

abstract：:In this study we examined the induction of heme oxygenase-1 (HO-1) in glia in the traumatized rat brain. HO-1 was immunolocalized in fixed sections of brain 3 h to 5 days after injury. Induction of this enzyme in astrocytes, microglia/macrophages, and oligodendrocytes was evaluated using immunofluorescent double label...

journal_title：Brain research

authors： Fukuda K,Richmon JD,Sato M,Sharp FR,Panter SS,Noble LJ

更新日期：1996-10-14 00:00:00

abstract：:This study investigated the long-lasting effects of chronic ethanol consumption on the distribution of Schaffer collateral-commissural (SCH/COM) afferents within stratum radiatum of rat hippocampal CA1. Experimental animals were fed an ethanol-containing liquid diet for 20 weeks but were withdrawn from the special die...

journal_title：Brain research

authors： Abraham WC,Manis PB,Hunter BE,Zornetzer SF,Walker DW

更新日期：1982-04-08 00:00:00

abstract：:We have examined the influence of reducing conditions on the activity of group-I or -II metabotropic glutamate receptors. In cultured cerebellar granule cells or in hippocampal slices, the reducing agent dithiothreitol (DTT) inhibited the stimulation of polyphosphoinositide (PPI) hydrolysis elicited by group-I mGlu re...

journal_title：Brain research

authors： Copani A,Romano C,Di Giorgi Gerevini V,Nicosia A,Casabona G,Storto M,Mutel V,Nicoletti F

更新日期：2000-06-09 00:00:00

abstract：:How general anaesthetic drugs cause unconsciousness is a topic of ongoing clinical and scientific interest. It is becoming increasingly apparent that they disrupt cortical information processing, but the effects appear to depend on the spatial scale under investigation. In this study we investigated whether the intrav...

journal_title：Brain research

authors： Voss LJ,Baas CH,Hansson L,Li D,Sleigh JW

更新日期：2013-08-14 00:00:00

abstract：:Glucocorticoids exacerbate aging-induced cell death, but relatively little is known about other CNS effects in senescence. We examined noradrenergic/adenylyl cyclase signaling in the cerebellum, which is a brain region that is susceptible to deterioration of synaptic function in aging. Aged control rats had increased ...

journal_title：Brain research

authors： Slotkin TA,Zhang J,McCook EC,Seidler FJ

更新日期：1998-08-03 00:00:00

abstract：:The properties of [3H]dihydropyridine (DHP), nitrendipine and (+)-PN 200-110, binding to rat cerebral membranes were investigated. In normotensive Wistar-Kyoto (WKY) adult rats, the highest densities of [3H]DHP binding sites were found in the hippocampus. Frontal cerebral cortex and hypothalamus had intermediate level...

journal_title：Brain research

authors： Huguet F,Huchet AM,Gerard P,Narcisse G

更新日期：1987-05-26 00:00:00