Formalin-induced nociception activates a monoaminergic descending inhibitory system.

abstract：:Rhyme processing is reflected in the electrophysiological signals of the brain as a negative deflection for non-rhyming as compared to rhyming stimuli around 450 ms after stimulus onset. Studies have shown that this N450 component is not solely sensitive to rhyme but also responds to other types of phonological overla...

journal_title：Brain research

authors： Wagensveld B,Segers E,Alphen Pv,Hagoort P,Verhoeven L

更新日期：2012-11-05 00:00:00

abstract：:ENT1 is an equilibrative nucleoside transporter that enables trans-membrane bi-directional diffusion of biologically active purines such as adenosine. In spinal cord dorsal horn and in sensory afferent neurons, adenosine acts as a neuromodulator with complex pro- and anti-nociceptive actions. Although uptake and relea...

journal_title：Brain research

authors： Governo RJ,Deuchars J,Baldwin SA,King AE

更新日期：2005-10-19 00:00:00

abstract：:Transthyretin (TTR) is mainly expressed in the liver and choroid plexus of the brain. The majority of familial amyloidotic polyneuropathy cases are caused by a mutant TTR gene. The origin of the TTR deposited in the peripheral nervous system is unknown. We studied the expression of TTR in the peripheral nerves of norm...

journal_title：Brain research

authors： Murakami T,Ohsawa Y,Zhenghua L,Yamamura K,Sunada Y

更新日期：2010-08-12 00:00:00

abstract：:Performance on object recognition and object placement memory tasks was evaluated after a short-dosing model of methamphetamine (MA) regime and monoamines and metabolites were measured post-testing. Adult male rats received three injections of 10 mg/kg at 2-h intervals. In striatum DA and 5-HT were depleted by 65% and...

journal_title：Brain research

authors： Bisagno V,Ferguson D,Luine VN

更新日期：2002-06-14 00:00:00

abstract：:Fos-like immunoreactivity (FLI) can indicate the location of neurons activated following expression of conditioned taste aversion (CTA). After one conditioning trial FLI has been identified in the intermediate nucleus of the solitary tract (iNTS) with little expression in other brain regions. The present study assesse...

journal_title：Brain research

authors： Navarro M,Spray KJ,Cubero I,Thiele TE,Bernstein IL

更新日期：2000-12-29 00:00:00

abstract：:Ovine corticotropin releasing factor (CRF) given intracerebroventricularly to rhesus monkeys at doses of 0.1-1 microgram/kg activates the pituitary-adrenal axis. The increases of plasma cortisol concentrations after intraventricular injection of CRF were similar to those observed after intravenous administration of th...

journal_title：Brain research

authors： Rock JP,Oldfield EH,Schulte HM,Gold PW,Kornblith PL,Loriaux L,Chrousos GP

更新日期：1984-12-10 00:00:00

abstract：:An in vitro preparation was used to determine if rapidly transported radiolabeled protein which is isolated with the myelin fraction of frog sciatic nerves is similar to rapidly transported radiolabeled protein released from sciatic nerves. Sciatic nerves along with their eighth and ninth dorsal root ganglia were plac...

journal_title：Brain research

authors： Edwards JA,Hines JF

更新日期：1982-05-13 00:00:00

abstract：:Numerous preclinical studies demonstrate that vagus nerve stimulation (VNS) paired with motor rehabilitation improves functional recovery after neural injuries such as stroke, traumatic brain injury, and spinal cord injury, in part by driving neural plasticity within the motor cortex. To date, these studies have been ...

journal_title：Brain research

authors： Tseng CT,Brougher J,Gaulding SJ,Hassan BS,Thorn CA

更新日期：2020-12-01 00:00:00

abstract：:The induction of gene expression has been correlated with long-lasting neuronal plasticity and long-term memory (LTM) formation. The fast activation of constitutive transcription factors by signaling mechanisms is thought to be the link between synaptic events and gene expression. However, only one constitutive transc...

journal_title：Brain research

authors： Freudenthal R,Romano A

更新日期：2000-02-14 00:00:00

abstract：:The purpose of the present study was to examine the effects of N-methyl-D-aspartate (NMDA) receptor blockade on the activity of tuberoinfundibular dopaminergic (TIDA) neurons in male and female rats. TIDA neuronal activity was estimated by measuring either the accumulation of 3,4-dihydroxyphenylalanine (DOPA) 30 min a...

journal_title：Brain research

authors： Wagner EJ,Moore KE,Lookingland KJ

更新日期：1993-05-14 00:00:00

abstract：:The brainstem nucleus, locus coeruleus (LC), is the major, if not the sole, source of noradrenergic (NE) innervation of the telencephalon. It is generally held that LC neurons project diffusely to the entire neuroaxis and this had been the basis for theories that postulate 'general' functions (sleep, attention, learni...

journal_title：Brain research

authors： Shipley MT,Halloran FJ,de la Torre J

更新日期：1985-03-11 00:00:00

abstract：:Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) is a potent neuroexcitatory compound which acts at the quisqualate class of excitatory amino acid receptors. In this study we describe the pharmacological characteristics and anatomical distribution of [3H]AMPA binding sites in rat brain using quantitativ...

journal_title：Brain research

authors： Monaghan DT,Yao D,Cotman CW

更新日期：1984-12-17 00:00:00

abstract：:The frequency-dependent effect of various anticonvulsant drugs on the conduction in central axons was studied in the corpus callosum of rat and guinea pig brain slices from the parietal region. Extracellularly recorded compound action potentials (CAPs) were evoked by either single stimulus or high frequency stimulatio...

journal_title：Brain research

authors： Silberstein E,Schleifstein-Attias D,Grossman Y

更新日期：1992-07-24 00:00:00

abstract：:The uptake of amino acids into slices of adult and newborn mouse brain was studied in relation to Na+ flow. (1) The level of Na+ and K+ incubated slices of brain depends on the ionic composition of the incubation medium. The intracellular levels of Na+ in adult tissue are below, in fetal tissue above, Na+ levels in th...

journal_title：Brain research

authors： Lajtha A,Sershen H

更新日期：1975-02-14 00:00:00

abstract：:The possibility has been mentioned that a change in the structure is responsible for the deviant behavioral activity of gamma-endorphin in extracts of postmortem brain and pituitary gland samples of schizophrenic patients. This paper describes the investigation of this possibility by means of: amino acid composition a...

journal_title：Brain research

authors： Bovenberg RA,Burbach JP,Wiegant VM,Veeneman GH,van Boom JH,Baas PD,Jansz HS,de Wied D

更新日期：1986-06-18 00:00:00

abstract：:Following a single intravitreal injection of 200 nmol of kainic acid (KA) to newly hatched chickens, there are acute and long-term effects on retinal ganglion cells in the chicken retina. Thirty min after injection, most ganglion cells showed cytoplasmic vacuolization. However, 14 days later, most ganglion cell soma a...

journal_title：Brain research

authors： Tung NN,Morgan IG,Ehrlich D

更新日期：1987-12-01 00:00:00

abstract：:Pentobarbital-anesthetized rats received electrical hindpaw stimulation every 10 s to elicit a maximal hindlimb withdrawal reflex. The integrated EMG response in the ipsilateral tibialis anterior was sampled by a computer which also controlled the timing of electrical stimuli applied to the brain. A suppression of the...

journal_title：Brain research

authors： Duysens J,Dom R,Gybels J

更新日期：1989-10-09 00:00:00

abstract：:Following lesions of the pyramidal tract in hamsters, retrograde changes were studied in the sensorimotor cortex and in the pyramidal tract axons proximal to the lesion, at survival times ranging from 2 weeks to 14 months. Severe cell shrinkage occurred in layer 5 pyramidal neurons as early as 2 weeks, but there was n...

journal_title：Brain research

authors： Kalil K,Schneider GE

更新日期：1975-05-16 00:00:00

abstract：:Male rats were treated with barbital supplied in their drinking water (daily dose around 200 mg/kg) for 50 weeks. When the treatment was stopped (day 0) spontaneous convulsions were monitored for the first 3 days of the abstinence. On day 3 a convulsion was induced by electricity in half of the rats (controls and barb...

journal_title：Brain research

authors： Wahlström G

更新日期：1983-05-05 00:00:00

abstract：:Previous studies have shown that within 24 h after ischemic insult, gerbils exhibit an increase in locomotor activity. Because activity gradually diminishes to normal levels with repeated testing, it has been argued that this behavior represents a reversible or transient effect of ischemia. The present study challenge...

journal_title：Brain research

authors： Babcock AM,Baker DA,Lovec R

更新日期：1993-10-22 00:00:00

abstract：:A small, unilateral, penetrating wound was placed in the dorsolateral portion of the lumbosacral spinal cord in immature rats. Although this wound did not extend into the central canal area, some cells forming the walls of this canal underwent proliferative activity as demonstrated by [3H]thymidine autoradiography. Th...

journal_title：Brain research

authors： Gilmore SA,Leiting JE

更新日期：1980-11-10 00:00:00

abstract：:17β-estradiol (E2 or estrogen) is an endogenous steroid hormone that is well known to exert neuroprotection. Along these lines, one mechanism through which E2 protects the hippocampus from cerebral ischemia is by preventing the post-ischemic elevation of Dkk1, a neurodegenerative factor that serves as an antagonist of...

journal_title：Brain research

authors： Scott EL,Brann DW

更新日期：2013-06-13 00:00:00

abstract：:Recent research has shown that familiarity contributes to associative memory when the to-be-associated stimuli are unitized during encoding. However, the specific processes underlying familiarity-based recognition of unitized representations are still indefinite. In this study, we present electrophysiologically dissoc...

journal_title：Brain research

authors： Wiegand I,Bader R,Mecklinger A

更新日期：2010-11-11 00:00:00

abstract：:These experiments were conducted in order to better understand the role of catecholaminergic neurons in intracranial self-stimulation behaviour (ICSS) elicited from the lateral hypothalamus (LH). Two strains of mice which differ in their ICSS rate and their thresholds were studied. In a first time, we compared the cat...

journal_title：Brain research

authors： Garrigues AM,Cazala P

更新日期：1983-04-18 00:00:00

abstract：:Activated monocytes/macrophages are known to release toxic materials. Identification of these materials is important for developing more effective treatments for inflammatory disorders where self attack occurs. We stimulated human monocytes and THP-1 cells with LPS/IFNγ and measured the toxic effects of their conditio...

journal_title：Brain research

authors： Lee M,Suk K,Kang Y,McGeer E,McGeer PL

更新日期：2011-07-11 00:00:00

abstract：:Male ICR mice were fed powdered laboratory chow containing phenobarbital for 7 days to induce tolerance. Mice were sacrificed and brains assayed for changes in GABA-mediated chloride flux into brain membrane vesicles (microsacs). Concentration-dependent stimulation of chloride flux by GABA alone was not affected by th...

journal_title：Brain research

authors： Allan AM,Zhang X,Baier LD

更新日期：1992-08-21 00:00:00

abstract：:To verify whether microtubules are involved in the mechanism of axoplasmic transport in vivo, [3H]leucine was injected into ventral horns of rats, and 3 h later Ca2+ or other drugs injected into sciatic nerves. The injection of 50-200 mM Ca2+, raising intra-axoplasmic Ca2+ levels, blocked transport above the intraneur...

journal_title：Brain research

authors： Gan SD,Fan MM,He GP

更新日期：1986-03-26 00:00:00

abstract：:In order to elucidate the mechanisms that PKCγ regulates neuropathic pain (NP), and detect proteins that are associated with the function of PKCγ in NP, we exploited a chronic constriction injury (CCI)-induced neuropathic pain rat (CCI-NP rat) model in which PKCγ knockdown in the spinal cord was successfully carried o...

journal_title：Brain research

authors： Zou W,Zhan X,Li M,Song Z,Liu C,Peng F,Guo Q

更新日期：2012-02-27 00:00:00

abstract：:The neurotoxic effects of exogenous glutamate were studied in the rat cochlea. Glutamate-treated rats (4 g/kg/day i.p., postnatal days 2-9) exhibited electrophysiologically-measured elevations in high frequency thresholds usually associated with hair cell loss in the basal region of the cochlea. While surface preparat...

journal_title：Brain research

authors： Janssen R,Schweitzer L,Jensen KF

更新日期：1991-06-28 00:00:00

abstract：:The relationship between carotid body chemoreceptor activity and flow was studied in preparations superfused in vitro. The carotid bodies were excised from pentobarbitone-anesthetized cats and superfused with modified Tyrode's solution, buffered with HEPES-NaOH to pH 7.41. The bath temperature was kept constant at 37....

journal_title：Brain research

authors： Alcayaga J,Iturriaga R,Zapata P

更新日期：1988-07-05 00:00:00