Abstract：
:Noxious heat applied to the footpad evokes the expression of fos protein-like immunoreactivity in the rat spinal cord lumbar dorsal horn. Electrical stimulation in the medullary nucleus raphe magnus (NRM) while not evoking fos-like immunoreactivity itself, reduced significantly the number of neurons (to 50% of control) in the dorsal horn demonstrating fos protein-like immunoreactivity in response to noxious heating of the footpad. Thus descending projections from the medullary NRM appear to have direct inhibitory effects on dorsal horn neurons that receive nociceptive input from cutaneous thermal nociceptors.
journal_name
Brain Resjournal_title
Brain researchauthors
Jones SL,Light ARdoi
10.1016/0006-8993(90)91306-2subject
Has Abstractpub_date
1990-10-22 00:00:00pages
335-8issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(90)91306-2journal_volume
530pub_type
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