Abstract：
:In normal adult rats, intense immunostaining for the 75 kDa low-affinity receptor for nerve growth factor and other neurotrophins (p75NGFR) is concentrated in the middle region of the cuneate nucleus (CN), distributed in a blotchy pattern similar to that of cytochrome oxidase (CO) activity. In the adult rats, partial dorsal rhizotomies (centered around the 7th and 8th cervical spinal segments) resulted in the complete disappearance of p75NGFR-like immunoreactivity within the ipsilateral CN, but did not affect the distribution of the CO blotches. Perinatal (postnatal day 1-8) damage to the ipsilateral forepaw and subsequent rearing to adulthood also resulted in significant disruption of the topographical expression of p75NGFR-like immunoreactivity within the CN, as well as--as previously reported--disruption of the CO blotches. Although the patterns of staining in intact adult rats are similar for CO staining and for p75NGFR-like immunoreactivity within the CN, the CO staining appears to be primarily associated with postsynaptic cells, while the p75NGFR-like immunostaining appears to be associated with primary afferent terminals.
journal_name
Brain Resjournal_title
Brain researchauthors
Foschini DR,Egger MD,Crockett DPdoi
10.1016/0006-8993(94)90051-5subject
Has Abstractpub_date
1994-05-16 00:00:00pages
1-12issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(94)90051-5journal_volume
646pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Heterotopic transplantations of brain vesicles of a quail embryo into a chick embryo were carried out in order to elucidate if CNS anlagen have plasticity in differentiation at the 7-10 somite stage. Quail cells are distinguished from chick cells due to the difference in nuclear morphology. The prosencephalon did not ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90231-y
更新日期：1990-03-12 00:00:00
abstract：:Starvation inhibits egg-laying in the snail, Lymnaea stagnalis. In starved animals the neurosecretory Caudo-Dorsal Cells (CDC), which produce the egg-laying hormone, are hyperpolarized as compared to the CDC of controls. However, they are more responsive to repetitive intracellular stimulation, which induces the hormo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90528-5
更新日期：1982-05-13 00:00:00
abstract：:The spinal cord projections of the 3 main forelimb nerves-median, radial and ulnar, were studied in the rat dorsal horn with transganglionic transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP), or using the disappearance of fluoride resistant acid phosphatase (FRAP) after nerve section. The projection ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91565-i
更新日期：1991-03-01 00:00:00
abstract：:To evaluate a hypothesized role of the vagus in the circannual metabolic cycle of hibernators, measures of annual weight gain, weight loss and cycle period were taken for the ground squirrel, Citellus lateralis, maintained in constant environmental conditions before and after subdiaphragmatic vagotomy. The surgery did...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90996-0
更新日期：1986-01-29 00:00:00
abstract：:This report examines the effect of decreasing serum osmolality on movement into the ventricular system of fluid and of test material injected into the brain. Trace quantities of 22NaCl and 125I-labeled cat serum albumin (CSA) were injected into cerebral white matter of cats. The rates of cerebrospinal fluid volume flo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90885-5
更新日期：1978-08-04 00:00:00
abstract：:A direct projection from rat mesencephalic trigeminal nucleus (Vme) neurons to the hypoglossal nucleus (XII) motoneurons was studied using a double labeling method of anterogradely biotinylated dextran amine (BDA) tracing combined with retrogradely horseradish peroxidase (HRP) transport at both light and electron micr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02911-0
更新日期：2001-10-26 00:00:00
abstract：:Using a double-label immunofluorescence method, we analyzed the time course of the appearance of Fos and Jun in the nuclei of supraoptic nucleus (SON) neurons following intraperitoneal injection of hypertonic saline. Fos and Jun immunostaining appeared within 30 min, peaked at 90-120 min, and disappeared 4-5 h later. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01216-4
更新日期：1997-01-23 00:00:00
abstract：:Synaptic glomeruli in the nucleus submedius of the rat are described and the source of some of the component terminals identified. The glomeruli consist of large terminals with round synaptic vesicles establishing Gray type I contacts with dendrites and surrounded by layers of astrocyte derived membranes. The astrocyt...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90215-0
更新日期：1987-07-14 00:00:00
abstract：:Both nictitating membrane extension and eyelid EMG activity were measured during classical conditioning of rabbits to tone-airpuff pairings. Both measures were highly correlated. Over trials, learning criterion was met earlier with eyelid EMG activity than with nictitating membrane extension. Within a trial, eyelid EM...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91419-h
更新日期：1990-04-30 00:00:00
abstract：:We screened anti-Aβ1-42 antibodies from a human Alzheimer's disease (AD) specific single chain variable fragment (scFv) phage display library and assessed their effects in APP/PS1 transgenic mice. Reverse transcription-PCR was used to construct the scFv phage display library, and screening identified 11A5 as an anti-A...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.01.028
更新日期：2016-03-15 00:00:00
abstract：:An involvement of serotonin (5-HT) 1A receptors in the etiology of psychiatric disorders has been suggested. Hypo-responsiveness of the 5-HT1A receptor is linked to anxiety and constitutive deletion of the 5-HT1A receptor produces anxiety-like behaviors in the mouse. Evidence that 5-HT1A receptor inactivation increase...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02271-5
更新日期：2001-05-25 00:00:00
abstract：:Neurofilament expression in peripheral olfactory neurons of adult rats was investigated by immunoblotting and immunohistochemistry using monoclonal antibodies specific for each of the 3 neurofilament proteins. Immunoblotting analysis of olfactory epithelium extracts demonstrated the presence of only the 200 kDa (NFH) ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90416-s
更新日期：1991-05-31 00:00:00
abstract：:Most functional neuroimaging techniques rely on activation-flow coupling (AFC) to detect changes in regional brain function, but AFC responses may also be altered during pathophysiological conditions such as ischemia. To define the relationship between progressive ischemia and the AFC response, graded levels of cerebr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.04.024
更新日期：2005-06-14 00:00:00
abstract：:The hypothalamic paraventricular nucleus is known to send projections to the dorsal medullary area where it appears to innervate the nucleus tractus solitarius and the dorsal motor nucleus of the vagus. Experiments were carried out in urethane anesthetized rats to identify single vagal motor neurons identified by anti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90399-3
更新日期：1985-04-15 00:00:00
abstract：:Somatosensory neurons including nociceptive ones in the medial thalamus have been studied extracellularly, and are classified into three types: nociceptive-specific, wide dynamic range, and tap neurons. However, the morphological characteristics of these three neurons have not yet been clarified. We studied the morpho...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91368-o
更新日期：1992-07-17 00:00:00
abstract：:The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS) also in noise induced hearing loss (NIHL) and anti-oxidants and free-radicals scavengers have been shown to attenuate the damage. Coenzyme Q(10) (CoQ(10)) or ubiquinone has a bioenergetic role as a component of the mithocondrial ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.12.027
更新日期：2009-02-27 00:00:00
abstract：:The development of spontaneous activity in response to morphine administration was studied at different postnatal ages in C57BL/6 mice. Morphine induced hyperactivity at all ages except in 3-week-old mice, in which a catatonic effect is evident. The results indicate that the neurophysiological and inhibitory systems r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(81)90029-8
更新日期：1981-11-01 00:00:00
abstract：:The second messenger cyclic GMP (cGMP) plays a role in the anxiolytic-like behavioral response of mice to nitrous oxide (N2O). This study was conducted to determine whether this behavioral effect of N2O is affected by inhibition of cGMP-dependent protein kinase (PKG). N2O-induced behavior in the light/dark exploration...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.01.015
更新日期：2005-03-15 00:00:00
abstract：:Instructions are an inextricable, yet poorly understood aspect of modern human life. In this paper we propose that instruction implementation and following can be understood as fast Hebbian learning in prefrontal cortex, which trains slower pathways (e.g., cortical-basal ganglia pathways). We present a computational m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.12.025
更新日期：2012-02-23 00:00:00
abstract：:S-allyl cysteine (SAC), a sulfur containing amino acid derived from garlic, has been reported to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was designed to examine the pre-treatment effects of SAC on cognitive deficits and oxidative damage in the hippocampus of intracerebroven...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.02.072
更新日期：2011-05-10 00:00:00
abstract：:The linear nucleus (Li) is a prominent cell group in the caudal hindbrain, which was first described in a study of cerebellar afferents in the rat by [Watson, C.R.R., Switzer, R.C. III, 1978. Trigeminal projections to cerebellar tactile areas in the rat origin mainly from N. interpolaris and N. principalis. Neurosci. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.02.068
更新日期：2009-05-19 00:00:00
abstract：:Abdominal musculature participates in generating a large number of behaviors and protective reflexes, although each abdominal muscle is frequently activated differentially during particular motor responses. For example, rectus abdominis has been reported to play less of a role in respiration than other abdominal muscl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02597-5
更新日期：2001-08-31 00:00:00
abstract：:Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)91187-3
更新日期：1983-11-28 00:00:00
abstract：:Although it is generally believed that the central projections of the retina in birds are entirely crossed, using wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) as an anterograde tracer, we have found that in normal posthatched chicks there is a small ipsilateral retinofugal projection to the dience...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(83)90124-4
更新日期：1983-10-01 00:00:00
abstract：:The olfactory sensory neurons are unique in the vertebrate nervous system in that they are replaced following experimentally induced degeneration. Unilateral removal of the olfactory bulb in hamster results in degeneration of all mature receptor neurons followed by a neurogenesis and partial replacement of the recepto...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90483-9
更新日期：1984-07-30 00:00:00
abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.08.036
更新日期：2013-11-06 00:00:00
abstract：:Male guinea pigs were given 3 tests for sexual behavior. Animals that never ejaculated were classified as low activity (LA), animals that ejaculated on one test were classified as medium activity (MA), and animals that ejaculated on two or more tests were classified as high activity (HA). Subsequently, animals from ea...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90929-x
更新日期：1976-03-19 00:00:00
abstract：:The lactating rat has been shown to lack a behavioral response and immediate early gene expression (cFos) in the hippocampus (Hipc) following intravenous or intracerebroventricular administration of an N-methyl-d-aspartate (NMDA) receptor agonist. The purpose of this study is to determine whether neurons in the Hipc h...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)01069-5
更新日期：1998-12-14 00:00:00
abstract：:An autoradiographic analysis of the time and sites of origin, and the migration and settling patterns of neurons was made in the spinal cord of the mouse. The neurons originated on days 10--14 of gestation with temporal gradients along the ventrodorsal and rostrocaudal axes. The motor neurons originated on days 10 and...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90105-1
更新日期：1978-12-22 00:00:00
abstract：:Intracellular and extracellular recordings from CA3 hippocampal neurons in vitro were used to study the ability of several NMDA (N-methyl-D-aspartate) receptor antagonists to suppress epileptiform bursts induced by NMDA and convulsants not thought to act at NMDA receptors. The antagonists, APV (D-2-amino-5-phosphonova...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90642-7
更新日期：1988-09-06 00:00:00
