Involvement of cyclic GMP-dependent protein kinase in nitrous oxide-induced anxiolytic-like behavior in the mouse light/dark exploration test.

abstract：:The drug 6-hydroxydopamine (6-OHDA) has been reported to reduce hypothalamic norepinephrine (NE) content after administration into the lateral ventricle without altering the dopamine content of tubero-infundibular neurons. Serum prolactin levels in male rats injected with 2 X 250 mug 6-OHDA were significantly higher t...

journal_title：Brain research

authors： Fenske M,Wuttke W

更新日期：1976-03-05 00:00:00

abstract：:The dopamine-releasing and depleting substance amphetamine (AMPH) can make cortical neurons susceptible to damage, and the prevention of hyperthermia, seizures and stroke is thought to block these effects. Here we report a 2-day AMPH treatment paradigm which affected only interneurons in three cortical regions with av...

journal_title：Brain research

authors： Jakab RL,Bowyer JF

更新日期：2002-12-20 00:00:00

abstract：:The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was studied in male hooded rats. Repeated kindling stimulations were delivered twice or three times daily until either 300 stimuli had been delivered or generalized convulsions had been observed to...

journal_title：Brain research

authors： Milgram NW,Michael M,Cammisuli S,Head E,Ferbinteanu J,Reid C,Murphy MP,Racine R

更新日期：1995-01-23 00:00:00

abstract：:In the diseased central nervous system, astrogliosis is accompanied by microglial activation. Depending on the context of their activation, reactive astrocytes are involved in neuronal survival and regeneration in an either protective or impedimental way. Major reactive changes of astrocytes in vivo are the upregulati...

journal_title：Brain research

authors： Röhl C,Lucius R,Sievers J

更新日期：2007-01-19 00:00:00

abstract：:The neocortex in chronically prepared rats is very resistant to the induction of long-term potentiation (LTP). In the first of two experiments described in this paper, we tried unsuccessfully to induce neocortical LTP within one session by coactivating basal forebrain cholinergic and cortical inputs to our neocortical...

journal_title：Brain research

authors： Racine RJ,Chapman CA,Trepel C,Teskey GC,Milgram NW

更新日期：1995-12-08 00:00:00

abstract：:A histochemical stain for cytochrome oxidase (CO) activity was used to examine the maturation of a neurochemical correlate of ON and OFF channels in the retina and dorsal lateral geniculate nucleus (LGN) of the tree shrew. In the adult tree shrew, the CO staining pattern can be used as a histochemical marker of segreg...

journal_title：Brain research

authors： Lachica EA,Condo GJ,Casagrande VA

更新日期：1987-08-01 00:00:00

abstract：:About 45% of the serotonergic raphe neurons are reported to express nerve growth factor (NGF) receptors. We therefore investigated whether selective serotonergic lesions of the median or dorsal raphe nuclei are associated with changes in NGF protein levels of the brain and whether the loss of serotonergic function alt...

journal_title：Brain research

authors： Hellweg R,Thomas H,Arnswald A,von Richthofen S,Kay S,Fink H,Morgenstern R,Hörtnagl H

更新日期：2001-07-13 00:00:00

abstract：:Cerebral cells of origin for the corticospinal (CST), corticopontine (CP), corticorubral (CR) and corticostriatal (CS) fibers in the rat were identified following the simultaneous retrograde transport of propidium iodide (PI), fast blue (FB), fluorogold (FG) and diamidino yellow (DY). PI was injected into the contrala...

journal_title：Brain research

authors： Akintunde A,Buxton DF

更新日期：1992-07-24 00:00:00

abstract：:Statistical analysis techniques that permit detection and quantification of EEG-single unit correlations were employed in a study of generalized penicillin epilepsy in the cat. Single unit activity was recorded in cerebral and cerebellar cortices and compared to the locally recorded EEG. It was found that during gener...

journal_title：Brain research

authors： Wray DV,Hablitz JJ

更新日期：1978-10-13 00:00:00

abstract：:The aim of this study was to describe the normal distribution of the water content in several regions of the rat brain and furthermore to determine if global ischemia results in a variable increase in water content in these regions. Water content was determined in 40 regions; in 8 unaffected brains by gravimetry and i...

journal_title：Brain research

authors： Schwab M,Bauer R,Zwiener U

更新日期：1997-02-21 00:00:00

abstract：:Blockade of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors with 6-nitro-7-sulfamoyl-benzo-[f]quinoxaline-2,3(1H,4H)-dione (NBQX) activates tuberoinfundibular (TIDA) and periventricular-hypophysial dopaminergic (PHDA) neurons suggesting that these neurons are tonically inhibited by endogenous...

journal_title：Brain research

authors： Wagner EJ,Moore KE,Lookingland KJ

更新日期：1994-10-17 00:00:00

abstract：:Distribution of somatostatin (SS) immunoreactivity was observed in the preoptic-anterior hypothalamus (PO-AH) of the female rat brain. Six specific rabbit antibodies A (SS-14), B (SS-28), C (SS-28 complete), D (SS 14 and SS-28 both), E (SS preprohormone) and F (GHRH) were used for immunostaining using Avidin-Biotin Co...

journal_title：Brain research

authors： Bhatnagar M

更新日期：2001-05-11 00:00:00

abstract：:The terminal areas and cells of origin of the projection from the dorsal column nuclei to the mesencephalon were investigated by the intra-axonal transport method. Following injection of wheat germ agglutinin-horseradish peroxidase conjugate into the dorsal column nuclei, anterograde labeling was observed in several r...

journal_title：Brain research

authors： Wiberg M,Blomqvist A

更新日期：1984-10-08 00:00:00

abstract：:The concentration of soluble glial fibrillary acidic (GFA) protein and the specific activity of glutamine synthetase (GS) were estimated in 11 central nervous system (CNS) regions of the 90-day-old rat. Marked differences were observed in the regional distribution of these astrocyte marker proteins. The striatum and s...

journal_title：Brain research

authors： Patel AJ,Weir MD,Hunt A,Tahourdin CS,Thomas DG

更新日期：1985-04-01 00:00:00

abstract：:Sex hormone binding globulin (SHBG) is produced in brain where it is often co-localized with oxytocin. Infusions of SHBG into the medial preoptic area-anterior hypothalamus facilitate female sexual receptivity. SHBG has receptors on plasma membranes of the prostate gland where binding of the 5alpha-reduced androgen di...

journal_title：Brain research

authors： Caldwell JD,Höfle S,Englöf I

更新日期：2002-09-06 00:00:00

abstract：:In kittens, but not in adult cats, depriving one eye of pattern vision by suturing the lids shut (monocular deprivation or MD) for one week reduces the proportion of binocular units in the visual cortex. A sensitivity of cortical units in adult cats to MD can be produced by infusing exogenous monoamines into the visua...

journal_title：Brain research

authors： McCall MA,Tieman DG,Hirsch HV

更新日期：1982-11-04 00:00:00

abstract：:The specific binding of [3H]kainic acid to hippocampal membranes was examined autoradiographically in rats kindled by tetanic stimulation of the amygdala or angular bundle. One day after the last of 3 class 4-5 kindled seizures, the specific binding of [3H]kainic acid in stratum lucidum of area CA3 was 47-61% less tha...

journal_title：Brain research

authors： Savage DD,Nadler JV,McNamara JO

更新日期：1984-12-03 00:00:00

abstract：:The development of spontaneous activity in response to morphine administration was studied at different postnatal ages in C57BL/6 mice. Morphine induced hyperactivity at all ages except in 3-week-old mice, in which a catatonic effect is evident. The results indicate that the neurophysiological and inhibitory systems r...

journal_title：Brain research

authors： Filibeck U,Castellano C,Oliverio A

更新日期：1981-11-01 00:00:00

abstract：:The periaqueductal gray was shown to be an important component of morphine analgesia and tolerance. Two-way analgesic cross tolerance was obtained between systemic and intracerebral morphine administrations when the intracerebral site was the periaqueductal gray. Rats were pretreated with intraperitoneal morphine and ...

journal_title：Brain research

authors： Jacquet YF,Lajtha A

更新日期：1976-02-27 00:00:00

abstract：:Focal electrical stimulation and glutamate microinjection in the nuclei reticularis gigantocellularis (NGC) and gigantocellularis pars alpha (NGC alpha) both inhibit the nociceptive tail-flick (TF) reflex in rats. The present experiments were undertaken to determine the transmitter(s) at the level of the lumbar spinal...

journal_title：Brain research

authors： Zhuo M,Gebhart GF

更新日期：1990-12-03 00:00:00

abstract：:To evaluate roles of the sympathetic nervous system in enhancing glucose uptake in skeletal muscles in response to electrical stimulation of the ventromedial hypothalamic nucleus (VMH), the effects of guanethidine treatment and adrenal demedullation on the response were examined in rats anesthetized and injected with ...

journal_title：Brain research

authors： Minokoshi Y,Okano Y,Shimazu T

更新日期：1994-06-27 00:00:00

abstract：:Myelin is probably one of the most fascinating and innovative biological acquisition: a glia plasma membrane tightly wrapped around an axon and insulating it. Chondrichthyans (cartilaginous fishes) form a large group of vertebrates, and they are among oldest extant jawed vertebrate lineage. It has been known from stud...

journal_title：Brain research

authors： de Bellard ME

更新日期：2016-06-15 00:00:00

abstract：:Cerebrospinal fluid (c.s.f.) pressure and resistance to absorption have been studied in exteriorized fetuses (18 to 21 days gestation) from pregnant rats anaesthetised with pentobarbitone and in similarly anaesthetised postnatal rats at 1, 5, 10 and 30 days after birth and in adults. The resting c.s.f. pressure was lo...

journal_title：Brain research

authors： Jones HC,Deane R,Bucknall RM

更新日期：1987-05-01 00:00:00

abstract：:Rat cerebral cortex slices were incubated in small volumes of medium in order to study the bidirectional movements of gamma-aminobutyric acid (GABA) between tissue and medium, and to measure the extent of release of endogenous amino acids of interest as potential neurotransmitters. The apparent uptake, real uptake, an...

journal_title：Brain research

authors： Cutler RW,Young J

更新日期：1979-04-13 00:00:00

abstract：:Bombesin-like immunoreactivity occurs in a dense network of nerve fibres in the rat coeliac-superior mesenteric ganglion. No bombesin immunoreactive cell bodies have been observed in this ganglion. An origin outside the ganglion was therefore assumed for the bombesin immunoreactive fibres. Ligation of the mesenteric n...

journal_title：Brain research

authors： Schultzberg M,Dalsgaard CJ

更新日期：1983-06-13 00:00:00

abstract：:The ganglion cells are the output neurons of the retina. There is, however, relatively little known about the neurotransmitters used by these cells. In the present study, ganglion cells identified with a ganglion cell-specific monoclonal antibody (AB5) are shown in separate double-label experiments to be gamma-aminobu...

journal_title：Brain research

authors： Yu BC,Watt CB,Lam DM,Fry KR

更新日期：1988-01-26 00:00:00

abstract：:While schizophrenia has a genetic component, its pathogenesis is unknown. Abnormal concentrations of two cell recognition molecules (CRMs), neural-cell adhesion molecule (N-CAM) and L1 antigen have been described in the cerebrospinal fluid (CSF) of patients with schizophrenia. Studies of monozygotic twins discordant f...

journal_title：Brain research

authors： Poltorak M,Wright R,Hemperly JJ,Torrey EF,Issa F,Wyatt RJ,Freed WJ

更新日期：1997-03-14 00:00:00

abstract：:Classical anatomical depictions of the cervical sympathetic trunk label it as a cholinergic preganglionic structure. We studied the cervical sympathetic trunk of the rat following daily injection for 5 weeks of guanethidine monosulphate, a regimen known to selectively destroy adrenergic neurons outside of the blood-br...

journal_title：Brain research

authors： Zochodne DW,Low PA,Dyck PJ

更新日期：1989-10-02 00:00:00

abstract：:Caspases, a family of cysteine proteases, are widely activated in neurons and glia in the injured brain, a response thought to induce apoptosis. However, caspase activation in astrocytes following injury is not strongly associated with apoptosis. The present study investigates the potential role of caspase activation ...

journal_title：Brain research

authors： Aras R,Barron AM,Pike CJ

更新日期：2012-04-23 00:00:00

abstract：:The expression of phosphorylated extracellular signal-regulated kinase 1/2 (pERK 1/2) was evaluated in the vestibular nuclei (VN) of rats following unilateral labyrinthectomy (UL). Immunohistochemistry revealed a significant asymmetrical increase in pERK 1/2 expression in the VN, 5 min after UL, after which pERK 1/2 i...

journal_title：Brain research

authors： Kim MS,Choi MA,Choi DO,Lee MY,Kim KY,Rhee JK,Jin YZ,Park BR

更新日期：2004-06-18 00:00:00