Distribution of somatostatin (SS) immunoreactivity using specific rabbit antibodies in preoptic-anterior hypothalamus (PO-AH) of female rat brain.

abstract：:Extracellular recordings were obtained from spontaneously active neurones located in the dorsal motor nucleus of vagus nerve ( DMX ) in slices of the rat brainstem. Oxytocin applied to the bath at concentrations of 10(-7) M or 10(-6) M excited 79% of these cells in a concentration-dependent, reversible manner. The rem...

journal_title：Brain research

authors： Charpak S,Armstrong WE,Mühlethaler M,Dreifuss JJ

更新日期：1984-05-21 00:00:00

abstract：:A role for altered iron metabolism in the pathogenesis of Alzheimer's disease has been suggested by several reports associating the cardinal neuropathologic lesions with markers of free radical-induced damage and redox-active iron. We hypothesized that the abnormal distribution of iron in Alzheimer brain might result ...

journal_title：Brain research

authors： Smith MA,Wehr K,Harris PL,Siedlak SL,Connor JR,Perry G

更新日期：1998-03-30 00:00:00

abstract：:The present study examined the antioxidant effect of phytic acid on iron (II)-enhanced hydroxyl radical (*OH) generation induced by 1-methyl-4-phenylpyridinium ion (MPP(+)) in the extracellular fluid of rat striatum. Rats were anesthetized, and sodium salicylate in Ringer's solution (0.5 nmol/microl/min) was infused t...

journal_title：Brain research

authors： Obata T

更新日期：2003-07-18 00:00:00

abstract：:A hypothalamic oxytocinergic-descending pathway that reaches the dorsal horn of the spinal cord has been well documented and recently related to states of pain and analgesia. In order to study the action of the neuropeptide oxytocin (OT) on pain-related responses, we compared dorsal horn neuronal responses to electric...

journal_title：Brain research

authors： Condés-Lara M,Maie IA,Dickenson AH

更新日期：2005-05-31 00:00:00

abstract：:The patch-clamp technique was used to characterize the single channel ion currents in primary cultures of rat astrocytes. The most dominant channel type, which was found in over half of the inside-out membrane patches, was a potassium channel. The measured reversal potential was -67 mV, which is close to the calculate...

journal_title：Brain research

authors： Jalonen T,Holopainen I

更新日期：1989-04-10 00:00:00

abstract：:The competitive CB1 receptor antagonist SR141716A was used to test the hypothesis that endogenous cannabinoids modulate tonic pain sensitivity. Pretreatment with the antagonist significantly enhanced the response to a chemical nociceptive stimulus in the formalin test. Postreatment with the antagonist 5 min following ...

journal_title：Brain research

authors： Strangman NM,Patrick SL,Hohmann AG,Tsou K,Walker JM

更新日期：1998-12-07 00:00:00

abstract：:Blink movement metrics were studied in three alert cynomolgus monkeys using electromagnetic search coils attached to the eyelids bilaterally. Monkey blinks averaged approximately 24 degrees. Down-phase peak velocities were approximately twice those of the corresponding up phases. Most blinks were symmetrical with clos...

journal_title：Brain research

authors： Porter JD,Stava MW,Gaddie IB,Baker RS

更新日期：1993-04-23 00:00:00

abstract：:Evidence is provided that carbonic anhydrase-II is localized in the central nervous system to wide spread systems of oligodendrocytes and restricted astroglia populations, involving both fiber bundles and neuropil. It is suggested that CO2 formed in activated axons may, via carbonic anhydrase-II, give rise to protons ...

journal_title：Brain research

authors： Agnati LF,Tinner B,Staines WA,Väänänen K,Fuxe K

更新日期：1995-04-03 00:00:00

abstract：:The present study combined masked priming with electrophysiological recordings to investigate orthographic priming effects with nonword targets. Targets were pronounceable nonwords (e.g., STRENG) or consonant strings (e.g., STRBNG), that both differed from a real word by a single letter substitution (STRONG). Targets ...

journal_title：Brain research

authors： Massol S,Midgley KJ,Holcomb PJ,Grainger J

更新日期：2011-04-22 00:00:00

abstract：:Three hours after administration of the pro-oxidant 2-cyclohexen-1-one, calpain activity was significantly reduced in the brain of young rats, but not in the brain of adult rats, and cathepsin D activity remained unchanged. Addition of isovalerylcarnitine to the incubation medium increased calpain activity 5-7-fold, c...

journal_title：Brain research

authors： Benuck M,Banay-Schwartz M,Ramacci MT,Lajtha A

更新日期：1992-11-20 00:00:00

abstract：:A clonal human embryonic kidney (HEK) 293 cell line was established that stably expressed the rat kappa-opioid receptor (rKOR) with a FLAG epitope at the amino terminus. The Kd for [3H]diprenorphine was 1.1+/-0.2 nM, and the Bmax was 2.6+/-0.4 pmol/mg. Dynorphin A (1-13), U69,593 and naloxone competitively inhibited [...

journal_title：Brain research

authors： Wannemacher KM,Terskiy A,Bian S,Yadav PN,Li H,Howells RD

更新日期：2008-09-16 00:00:00

abstract：:Rats received 1-stage bilateral and sequential unilateral (serial) lesions of the posterior hypothalamus and were tested for the ability to regulate body temperature after a lengthy recovery period. The groups with lesion differed from the sham-operated groups in the cold, although not under ambient or warm conditions...

journal_title：Brain research

authors： Bell J,Gruenthal M,Finger S,Mangold R

更新日期：1981-08-31 00:00:00

abstract：:Fractionated partial or whole-brain irradiation (fWBI) is a widely used, effective treatment for primary and metastatic brain tumors, but it also produces radiation-induced brain injury, including cognitive impairment. Radiation-induced neural changes are particularly problematic for elderly brain tumor survivors who ...

journal_title：Brain research

authors： Shi L,Olson J,D'Agostino R Jr,Linville C,Nicolle MM,Robbins ME,Wheeler KT,Brunso-Bechtold JK

更新日期：2011-04-18 00:00:00

abstract：:The effects of clonidine (CLO) and phentolamine (PHE) on the sleep-waking cycle in the cat treated with alpha-methyl-p-tyrosine (AMPT) were investigated with continuous 16--24 h polygraphic recordings. For the evaluation of possible cholinergic interactions in the paradoxical sleep (PS) increasing effect of AMPT, an a...

journal_title：Brain research

authors： Leppävuori A

更新日期：1980-07-07 00:00:00

abstract：:The anatomical structure of the basal ganglia indicates that the input from the cerebral cortex is funnelled through the striatum to the globus pallidus and substantia nigra. This structure implies integration of the information as it is transferred through the basal ganglia. In order to investigate this integration, ...

journal_title：Brain research

authors： Loopuijt LD,van der Kooy D

更新日期：1985-11-25 00:00:00

abstract：:Activation of cAMP-dependent protein kinase (kinase A) has recently been shown to enhance responses evoked by stimulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors in cultured hippocampal pyramidal neurons. Here we report results of experiments designed to determine if activation of the...

journal_title：Brain research

authors： Chavez-Noriega LE,Stevens CF

更新日期：1992-03-06 00:00:00

abstract：:From previous inverse dynamic analyses of human leg extensions, it was hypothesized that the underlying processes for the activation of mono- and biarticular muscles are different; the mono-articular muscles being activated when they shortened, whereas the biarticular muscles appeared responsible for the control of th...

journal_title：Brain research

authors： Doorenbosch CA,Welter TG,van Ingen Schenau GJ

更新日期：1997-03-21 00:00:00

abstract：:GABA-A receptors mediate both phasic synaptic inhibition and more recently appreciated tonic currents in the vertebrate central nervous system. We addressed discrepancies in the literature regarding the pharmacology of tonic currents by examining tonic currents in a controlled environment of dissociated, solitary glut...

journal_title：Brain research

authors： Eisenman LN,Kress G,Zorumski CF,Mennerick S

更新日期：2006-11-06 00:00:00

abstract：:Effects of protein kinase C (PKC) activation on the function of the GABA/benzodiazepine receptor-chloride complex were analyzed by quantitative autoradiography using [3H]muscimol, [3H]flunitrazepam and [35S]TBPS in rat brain slices. The density of [3H]muscimol binding was highest in cerebellar granular layers and high...

journal_title：Brain research

authors： Oh S,Jang CG,Ma T,Ho IK

更新日期：1999-12-11 00:00:00

abstract：:In rats, True Blue (or Granular Blue) was injected into the hippocampus of one hemisphere and Nuclear Yellow into a homotopic site of the hippocampus of the contralateral hemisphere. Following restricted injections into the septal part of area dentata fluorescent neurons were found in hilus fasciae dentate on both sid...

journal_title：Brain research

authors： Laurberg S,Sørensen KE

更新日期：1981-05-18 00:00:00

abstract：:The involvement of the nucleus intercollicularis (ICo) region of the midbrain, an estrogen-sensitive area, in the expression of estrogen-dependent female courtship behavior was examined with radiofrequency lesion and intracranial hormone implant techniques. Bilateral lesions in the ICo region caused a reduction in the...

journal_title：Brain research

authors： Cohen J,Cheng MF

更新日期：1981-03-02 00:00:00

abstract：:There have been few reports concerning facilitation and depression in sympathetic ganglia9,17,40. In the present investigation, pairs of excitatory postsynaptic potentials (EPSPs) were recorded intracellularly from bullfrog paravertebral sympathetic ganglia for an analysis of the site and mechanism responsible for the...

journal_title：Brain research

authors： Tashiro N,Gallagher JP,Nishi S

更新日期：1976-12-10 00:00:00

abstract：:We examined the effects of chronic social stress and social rank on monamine concentrations in the prefrontal cortex (PFC) in adult male cynomolgus macaques (Macaca fascicularis). Seventy-five animals were housed in five-member social groups for 28 months and were exposed to three experimental conditions. A 'no-stress...

journal_title：Brain research

authors： Fontenot MB,Kaplan JR,Manuck SB,Arango V,Mann JJ

更新日期：1995-12-24 00:00:00

abstract：:In the present study, we used an innovative music-rest interleaved fMRI paradigm to investigate the neural correlates of tinnitus distress. Tinnitus is a poorly-understood hearing disorder where individuals perceive sounds, in the absence of an external source. Although the great majority of individuals habituate to c...

journal_title：Brain research

authors： Shahsavarani S,Schmidt SA,Khan RA,Tai Y,Husain FT

更新日期：2021-01-07 00:00:00

abstract：:Previous work had indicated that animals that were sleep-deprived and then trained on a passive avoidance task show poor retention of the task 24 h later after being allowed to sleep freely again. Cholinergic involvement is suggested by the fact that this effect is prevented by treatment with the muscarinic agonist pi...

journal_title：Brain research

authors： Moreira KM,Hipólide DC,Nobrega JN,Bueno OF,Tufik S,Oliveira MG

更新日期：2003-07-04 00:00:00

abstract：:Noradrenaline effects on oxidative metabolism (tricarboxylic acid cycle activity) were examined by measuring the formation of 14CO2 from labeled aspartate in primary cultures of cerebral astrocytes and neurons and of cerebellar granule cells. At all time periods studied, CO2 formation in astrocytes was significantly i...

journal_title：Brain research

authors： Subbarao KV,Hertz L

更新日期：1990-09-17 00:00:00

abstract：:Oral ENA713 (0.5, 1.5 and 4.5 mg/kg), an acetylcholinesterase inhibitor (AChEI), dose-dependently enhanced extracellular acetylcholine concentrations in the hippocampus of freely moving rats. This effect was paralleled by changes in both noradrenergic and dopaminergic transmission. In particular, ENA713 significantly ...

journal_title：Brain research

authors： Trabace L,Coluccia A,Gaetani S,Tattoli M,Cagiano R,Pietra C,Kendrick KM,Cuomo V

更新日期：2000-05-26 00:00:00

abstract：:Noda epileptic rat (NER), originally found in a colony of Crj; Wistar rats, shows spontaneous tonic-clonic convulsion characterized by the appearance of high voltage polyspikes in cortical and hippocampal EEG once every 2-3 days after 2-4 months of age. Electrophysiological studies using hippocampal slice preparations...

journal_title：Brain research

authors： Hanaya R,Sasa M,Kiura Y,Ishihara K,Serikawa T,Kurisu K

更新日期：2002-09-20 00:00:00

abstract：:Histopathological analyses of brains of rats receiving a single 0.9 LD50 injection of soman, a potent anticholinesterase neurotoxin, revealed massive widespread lesions in the cerebral cortex and thalamus 4 weeks post-injection. Such lesions were not evidenced in rats receiving diazepam (2.2 mg/kg, i.m.) 10 min prior ...

journal_title：Brain research

authors： Martin LJ,Doebler JA,Shih TM,Anthony A

更新日期：1985-01-28 00:00:00

abstract：:Neuropathic pain remains a major complication of various forms of injury to peripheral nerves in humans. Recently, 2 models of peripheral mononeuropathy in the rat have been described which closely resemble the human condition. Bennett and Xie3 described one model induced by the placement of 4 loose ligatures around t...

journal_title：Brain research

authors： Dougherty PM,Garrison CJ,Carlton SM

更新日期：1992-01-20 00:00:00