Modulation of synaptic efficacy in field CA1 of the rat hippocampus by forskolin.

abstract：:A positive association between cardiorespiratory fitness (CRF) and white matter integrity has been consistently reported in older adults. However, it is unknown whether this association exists in adults over 80 with a range of chronic disease conditions and low physical activity participation, which can influence both...

journal_title：Brain research

authors： Tian Q,Simonsick EM,Erickson KI,Aizenstein HJ,Glynn NW,Boudreau RM,Newman AB,Kritchevsky SB,Yaffe K,Harris T,Rosano C,Health ABC study.

更新日期：2014-11-07 00:00:00

abstract：:Traumatic injury to the peripheral and central nervous systems very often causes axotomy, where an axon loses connections with its target resulting in loss of function. The axon segments distal to the injury site lose connection with the cell body and degenerate. Axotomized neurons in the periphery can spontaneously m...

journal_title：Brain research

authors： Smith TP,Sahoo PK,Kar AN,Twiss JL

更新日期：2020-08-01 00:00:00

abstract：:Oral ENA713 (0.5, 1.5 and 4.5 mg/kg), an acetylcholinesterase inhibitor (AChEI), dose-dependently enhanced extracellular acetylcholine concentrations in the hippocampus of freely moving rats. This effect was paralleled by changes in both noradrenergic and dopaminergic transmission. In particular, ENA713 significantly ...

journal_title：Brain research

authors： Trabace L,Coluccia A,Gaetani S,Tattoli M,Cagiano R,Pietra C,Kendrick KM,Cuomo V

更新日期：2000-05-26 00:00:00

abstract：:Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system. We have investigated the effects of NT incubation with rat neostriatal slices on calcium/calmodulin (Ca/CaM)-dependent protein phosphorylation. Slices were incubated with NT (5 or 50 nM) fo...

journal_title：Brain research

authors： Kasckow J,Cain ST,Nemeroff CB

更新日期：1991-04-05 00:00:00

abstract：:Full limbic seizures were kindled in rats by repeated, bi-daily microinjections of glutamate (1.5 mumol) into the basolateral amygdala. Co-administration of the N-methyl-D-aspartate (NMDA) receptor antagonist 2-amino-7-phosphonoheptanoic acid with the glutamate, prevented the development of both electroencephalographi...

journal_title：Brain research

authors： Croucher MJ,Bradford HF

更新日期：1990-01-08 00:00:00

abstract：:Unitary discharges in the efferent ciliary nerves were studied in cervical sympathectomized rabbits. In all, 279 units were recorded and categorized, except 7 units, into the following 3 types from their responses to photic and other stimuli, i.e. type A (170 units), type B (42 units) and type C (60 units). Type A uni...

journal_title：Brain research

authors： Inoue T

更新日期：1980-03-17 00:00:00

abstract：:The objective of this study was to further investigate neurochemicals which might modulate congenital differences in sensitivity to the acute and chronic effects of ethanol. Catecholamine levels were measured in the cortex, hippocampus, midbrain and cerebellum of long-sleep (LS) and short-sleep (SS) mice. These measur...

journal_title：Brain research

authors： Shafik EN,Aiken SP,McArdle JJ

更新日期：1991-11-01 00:00:00

abstract：:We used double-barreled pH-sensitive microelectrodes to study the mechanisms by which the intracellular pH is regulated in the connective glial cells of the medicinal leech. The experiments indicate that a Cl(-)- and HCO3(-)-dependent mechanism mediates some recovery from intracellular alkalosis even in the absence of...

journal_title：Brain research

authors： Szatkowski MS,Schlue WR

更新日期：1994-11-28 00:00:00

abstract：:The olivary pretectal nucleus is a primary visual centre sensitive to luminance changes. It is involved in the pupillary light reflex, the consensual pupillary light reflex and related reflexes, such as the lid closure reflex whereby pupillary constriction takes place. Since the olivary pretectal nucleus is a small nu...

journal_title：Brain research

authors： Klooster J,Vrensen GF,Müller LJ,van der Want JJ

更新日期：1995-08-07 00:00:00

abstract：:Previous studies have shown that pyramidal neurons in hippocampal regions CA1 and CA3 are selectively vulnerable in several neurodegenerative disorders and that a subpopulation of pyramidal neurons in cell cultures of embryonic hippocampus are sensitive to glutamate neurotoxicity. In order to determine whether the pat...

journal_title：Brain research

authors： Mattson MP,Kater SB

更新日期：1989-06-19 00:00:00

abstract：:The two neurosteroids 3alpha-hydroxy-5alpha-pregnane-20-one (allopregnanolone; AlloP) and pregnenolone sulfate (PregS) affect neuronal GABA(A) receptors differently. While AlloP mainly potentiates the currents through GABA(A) receptors, PregS reduces such currents. The present study aimed at clarifying the interaction...

journal_title：Brain research

authors： Haage D,Bäckström T,Johansson S

更新日期：2005-02-01 00:00:00

abstract：:The aim of this study was to investigate the degree of functional and anatomical overlap between two major neuronal subpopulations in the rostral ventrolateral medulla: pre-sympathetic (sympathoexcitatory) neurons, and expiratory neurons of the Bötzinger complex. Extracellular recordings were made with dye-filled micr...

journal_title：Brain research

authors： Kanjhan R,Lipski J,Kruszewska B,Rong W

更新日期：1995-11-13 00:00:00

abstract：:The present study examines the effects of ibotenic acid lesions of the medial amygdala, the bed nucleus of the stria terminalis and the medial preoptic area on the display of paced mating behavior in female rats. Lesions of either the medial amygdala or the bed nucleus of the stria terminalis have no effect on the dis...

journal_title：Brain research

authors： Guarraci FA,Megroz AB,Clark AS

更新日期：2004-02-27 00:00:00

abstract：:Several labeled neurotransmitter substances or precursors ( [3H]histamine, [3H]serotonin, and [3H]choline) were injected with pressure into the cell body of C2, an identified putative histaminergic neuron in the cerebral ganglion of Aplysia in order to study the selectivity of axonal transport. We examined transport o...

journal_title：Brain research

authors： Gotoh H,Schwartz JH

更新日期：1982-06-17 00:00:00

abstract：:Using one microelectrode inserted into a Limulus retinular cell, simultaneous recordings were made of the receptor potential evoked by light falling on that retinular cell and of the optic nerve action potentials generated in the eccentric cell coupled to that retinular cell. The postreceptor transfer function for sen...

journal_title：Brain research

authors： Wang LT,Wasserman GS

更新日期：1985-02-25 00:00:00

abstract：:Studies have demonstrated defects of DA and 5HT neurotransmission in dietary fat induced obese animals. In the present study, we used a perfusion system to assay the release of DA and 5HT from striatal slices preloaded with [(3)H]-DA or [(3)H]-5HT. The release of both DA and 5HT from striatal slices of rats fed a high...

journal_title：Brain research

authors： York DA,Teng L,Park-York M

更新日期：2010-08-19 00:00:00

abstract：:The effects of exogenous Cushing's syndrome on the brain metabolism were investigated by proton magnetic resonance spectroscopy (MRS). Thirteen patients having been treated for 2 to 22 years with prednisone were recruited. On the average, none of the metabolites (NAA, Cr, Cho and mI) were significantly different from ...

journal_title：Brain research

authors： Khiat A,Yared Z,Bard C,Lacroix A,Boulanger Y

更新日期：2001-08-24 00:00:00

abstract：:In vivo release of labeled serotonin ([3H]5-HT) from the parietal cortex was investigated by cortical cup technique and electrical stimulation of midbrain raphe in rats anesthetized with pentobarbital sodium. The spontaneous efflux of tritium from the parietal cortex preload with [3H]5-HT followed a multiphasic expone...

journal_title：Brain research

authors： Fujiwara H,Uemoto M,Tanaka C

更新日期：1981-07-20 00:00:00

abstract：:The response of neurons in the preoptic and adjacent regions of the brain to intracarotid injection of hyperosmotic solutions was studied in 22 anesthetized cats. NaCl (0.5 M) caused a brisk acceleration of frequency lasting over 100 s in 120 of 207 units (58%). Glucose (2 M) and sucrose (2 M) had similar but smaller ...

journal_title：Brain research

authors： Hubbard JI,Mills RG,Sirett NE

更新日期：1985-10-21 00:00:00

abstract：:Toxoplasma gondii can cause parasitic encephalitis, a life-threatening infection that predominately occurs in immunocompromised individuals. T. gondii has the ability to invade the brain, but the mechanisms by which this parasite crosses the blood-brain-barrier (BBB) remain incompletely understood. The present study r...

journal_title：Brain research

authors： Harun MSR,Marsh V,Elsaied NA,Webb KF,Elsheikha HM

更新日期：2020-11-01 00:00:00

abstract：:Poor sleep and insomnia have been recognized to be strongly correlated with the development of depression. The exploration of the basic mechanism of sleep disturbance could provide the basis for improved understanding and treatment of insomnia and prevention of depression. In this study, 31 subjects with insomnia symp...

journal_title：Brain research

authors： Liu CH,Liu CZ,Zhang J,Yuan Z,Tang LR,Tie CL,Fan J,Liu QQ

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The modern brain imaging studies in patients with eating disorders have shown that neurotransmitting regulation differs distinctly from control groups. These disturbances have involved serotonin and dopamine system can be inherited and conditioned by genes. The aim of this work has been the analysis of associ...

journal_title：Brain research

authors： Mikołajczyk E,Grzywacz A,Samochowiec J

更新日期：2010-01-11 00:00:00

abstract：:Fast B neurons in bullfrog sympathetic ganglia were voltage clamped with two microelectrodes. Acetylcholine (ACh) was applied onto the soma membrane by iontophoresis. A rapid nicotinic inward current was followed by a slow muscarinic inward current. After an addition of scopolamine to Ringer solution so as to block th...

journal_title：Brain research

authors： Tokimasa T,North RA

更新日期：1984-03-19 00:00:00

abstract：:The regulation of circadian rhythms changes with age. In humans, changes in the timing of sleep and wakefulness are especially common. In Syrian hamsters Mesocricetus auratus the free running period of the activity/rest rhythm shortens with age. The present study tested the hypothesis that critical age-related changes...

journal_title：Brain research

authors： Viswanathan N,Davis FC

更新日期：1995-07-17 00:00:00

abstract：:Following a mild cortical impact injury delivered by a piston to the right sensorimotor cortex of the anesthetized rat, we evaluated mantle loss, neuronal changes, and fiber track degeneration by deOlmos silver stains up to 8 weeks after injury. Darkened neurons indicating damage (chromatolysis) occurred widely throug...

journal_title：Brain research

authors： Matthews MA,Carey ME,Soblosky JS,Davidson JF,Tabor SL

更新日期：1998-05-25 00:00:00

abstract：:In vitro uptake of labeled serotonin (5-HT) has allowed the radioautographic detection of serotoninergic fibers in the cat spinal cord at thoracic and lumbar levels. The specificity of labeling was ensured by the conditions of incubation ([3H]5-HT was 10(-7) M) and by test control experiments with concomitant 10(-6) M...

journal_title：Brain research

authors： Segu L,Calas A

更新日期：1978-09-29 00:00:00

abstract：:Angiotensin converting enzyme (ACE) is Zn2+ metallopeptidase which plays an important role in blood pressure homeostasis in mammals and other vertebrates. Homologues of ACE involved in the biosynthesis of mammalian peptide hormones have also been identified in the insects, Musca domestica, Drosophila melanogaster and ...

journal_title：Brain research

authors： Schoofs L,Veelaert D,De Loof A,Huybrechts R,Isaac E

更新日期：1998-03-02 00:00:00

abstract：:We investigated the bilateral organization of the descending spinal sympathetic projections that subserve adrenomedullary stimulation caused by insulin hypoglycemia or 2-deoxyglucose (2DG) cellular glucopenia in adult rats with right-sided hemisection of the cord at C6-C7 (i.e. above the site of origin of the adrenal ...

journal_title：Brain research

authors： Gagner JP,Gauthier S,Sourkes TL

更新日期：1985-01-28 00:00:00

abstract：:Morphologically distinct subsets of mesotelencephalic neurons were sought following retrograde transport of Fluoro-Gold from iontophoretic injections relatively restricted to the medial shell, core or rostral pole subterritories of the nucleus accumbens. The diameter and lengths of Fluoro-Gold immunolabeled dendrites ...

journal_title：Brain research

authors： Tan Y,Brog JS,Williams ES,Zahm DS

更新日期：1995-08-14 00:00:00

abstract：:Neurons (n = 107) were recorded, in anaesthetized rats, with extracellular micropipettes, in the nucleus centralis of the amygdala (Ce). The activity of a large majority (77%) was exclusively or preferentially affected by noxious stimuli applied in any area of the body. The rest of the neurons was not activated by any...

journal_title：Brain research

authors： Bernard JF,Huang GF,Besson JM

更新日期：1990-07-23 00:00:00