Peroxidative stress effects on calpain activity in brain of young and adult rats.

Abstract:

:Three hours after administration of the pro-oxidant 2-cyclohexen-1-one, calpain activity was significantly reduced in the brain of young rats, but not in the brain of adult rats, and cathepsin D activity remained unchanged. Addition of isovalerylcarnitine to the incubation medium increased calpain activity 5-7-fold, counteracting the effect of the pro-oxidant.

journal_name

Brain Res

journal_title

Brain research

authors

Benuck M,Banay-Schwartz M,Ramacci MT,Lajtha A

doi

10.1016/0006-8993(92)91560-2

subject

Has Abstract

pub_date

1992-11-20 00:00:00

pages

296-8

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(92)91560-2

journal_volume

596

pub_type

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