Neonatal facial nerve extirpations fail to produce alterations in the barrel field in the primary somatosensory cortex of mice.

abstract：:We have previously described a rodent model of brief (30 min) middle cerebral artery occlusion followed by reperfusion, in which infarction develops gradually, reaching completion more than 3 days after ischemia, accompanied by morphological, biochemical, and pharmacological evidence of apoptosis. In the present study...

journal_title：Brain research

authors： Snider BJ,Du C,Wei L,Choi DW

更新日期：2001-11-02 00:00:00

abstract：:Horseradish peroxidase application in exsanguinated, pre-perfused newts, Pleurodeles waltlii, appeared to be very useful to study the connections of the area octavolateralis. Efferents from the octavolateral area course via bilateral lemnisci to the tectum and a presumptive torus semicircularis in the midbrain. Additi...

journal_title：Brain research

authors： Gonzalez A,Munoz M

更新日期：1987-10-13 00:00:00

abstract：:We used double staining immunocytochemical techniques to determine whether nitric oxide (NO) and Fos immunoreactivity induced by noxious visceral stimulation were colocalized in the neurons of the supraspinal areas. We observed a considerable increase in Fos-positive neurons in many brain areas after noxious stimulati...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1999-07-10 00:00:00

abstract：:We investigated the effect of Cerebrospinal Fluid (CSF) from sporadic Amyotrophic Lateral Sclerosis patients (SALS-CSF) on motor neuron-like cells to delineate the pathomechanism of SALS. Exposure of NSC-34 cells to SALS-CSF caused lower viability, reduction in differentiation and enhanced lactate dehydrogenase activi...

journal_title：Brain research

authors： Vijayalakshmi K,Alladi PA,Sathyaprabha TN,Subramaniam JR,Nalini A,Raju TR

更新日期：2009-03-31 00:00:00

abstract：:In a recent study in the tiger salamander, Ambystoma tigrinum, were demonstrated topographic patterns of responsivity across the olfactory epithelium which were characteristic for each odorant. The present study was initiated to investigate whether these patterns remain constant when odorant concentration is varied. O...

journal_title：Brain research

authors： Mackay-Sim A,Shaman P

更新日期：1984-04-16 00:00:00

abstract：:Using a double-label immunofluorescence method, we analyzed the time course of the appearance of Fos and Jun in the nuclei of supraoptic nucleus (SON) neurons following intraperitoneal injection of hypertonic saline. Fos and Jun immunostaining appeared within 30 min, peaked at 90-120 min, and disappeared 4-5 h later. ...

journal_title：Brain research

authors： Wang K,Guldenaar SE,McCabe JT

更新日期：1997-01-23 00:00:00

abstract：:The understanding of sarcasm reflects a complex process, which involves recognizing the beliefs of the speaker. There is a clear association between deficits in mentalizing, which is the ability to understand other people's behavior in terms of their mental state, and the understanding of sarcasm in individuals with a...

journal_title：Brain research

authors： Uchiyama H,Seki A,Kageyama H,Saito DN,Koeda T,Ohno K,Sadato N

更新日期：2006-12-08 00:00:00

abstract：:We investigated the projection from the infralimbic division of the prefrontal cortex (area 25) to histaminergic neurons in the posterior hypothalamic area. Phaseolus vulgaris-leucoagglutinin (PHA-L) was injected in the prefrontal cortex of rats. Frozen brain sections were subjected to combined PHA-L and histidine dec...

journal_title：Brain research

authors： Wouterlood FG,Steinbusch HW,Luiten PG,Bol JG

更新日期：1987-03-17 00:00:00

abstract：:It has been hypothesized that mitochondrial respiratory chain dysfunction leads to a pyrimidine deficiency since the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase is coupled to the electron transport chain. The uridine prodrug triacetyluridine (PN401) is neuroprotective in several models of neurodegenera...

journal_title：Brain research

authors： Garcia RA,Liu L,Hu Z,Gonzalez A,von Borstel RW,Saydoff JA

更新日期：2005-12-20 00:00:00

abstract：:The goal of the present study was to identify the projection from the subdivisions of the amygdaloid nuclear complex to specified subregions of the dorsal raphe (DR) nucleus and to attempt to compare the density of amygdaloid input to the DR with that of inputs from other limbic structures. Use of a retrograde tracer,...

journal_title：Brain research

authors： Lee HS,Eum YJ,Jo SM,Waterhouse BD

更新日期：2007-04-27 00:00:00

abstract：:The dtsz mutant hamster represents a model of primary paroxysmal dystonia, in which dystonic episodes occur in response to stress. Previous examinations demonstrated striatal dysfunctions in dtsz hamsters. In the present study, in situ hybridization was used to examine preproenkephalin and prodynorphin expression as p...

journal_title：Brain research

authors： Nobrega JN,Parkes JH,Wong P,Raymond R,Richter A

更新日期：2004-07-23 00:00:00

abstract：:In 16-week-old Sprague-Dawley rats lightly anesthetized with pentobarbital, 5-HT (3-96 micrograms/kg, i.v.; n = 6) produced distinct pseudaffective responses and a dose-dependent (slope = 17.2 +/- 6.8 s/log10 dose) inhibition of the tail-flick (TF) reflex (ED50 = 32.6 +/- 9.2 micrograms/kg). In the same rats, a 1:1 co...

journal_title：Brain research

authors： Meller ST,Lewis SJ,Brody MJ,Gebhart GF

更新日期：1991-10-04 00:00:00

abstract：:Acetylcholinesterase (AChE) histochemical staining occurred in neurons of the dentate gyrus at the day of birth and steadily increased in intensity and distribution during the first 3 postnatal weeks until the adult pattern was reached. Granule cells failed to display AChE staining; however, the somata of most non-pri...

journal_title：Brain research

authors： Seress L,Robertson RT,Ribak CE

更新日期：1987-11-01 00:00:00

abstract：:Microinjection of the indirect GABAA antagonist, picrotoxin, or the mu opioid agonist, Tyr-D-Ala-Gly-NMe-Phe-Gly-ol (DAGO), into the ventral pallidum and substantia innominata (VP/SI) increases locomotor activity in rats. The VP/SI has direct and indirect projections to the region of the ventral mesencephalon containi...

journal_title：Brain research

authors： Austin MC,Kalivas PW

更新日期：1991-02-22 00:00:00

abstract：:Previous studies in piglets show that opioid-induced pial artery dilation was impaired following fluid percussion brain injury (FPI). This study was designed to determine the role of the newly described opioid nociceptin orphanin FQ (NOC/oFQ) in such impaired dilation to other opioids after FPI. CSF NOC/oFQ concentrat...

journal_title：Brain research

authors： Armstead WM

更新日期：2000-06-30 00:00:00

abstract：:A group of neurons in the caudal nucleus of the solitary tract (NTS) processes preproglucagon to glucagon-like peptide 1 (GLP-1), GLP-2 and oxyntomodulin. Whereas the anorectic capacity of all three neuropeptides has been demonstrated, only relatively little is known of preproglucagon mRNA regulation in the brain stem...

journal_title：Brain research

authors： Vrang N,Larsen PJ,Jensen PB,Lykkegaard K,Artmann A,Larsen LK,Tang-Christensen M

更新日期：2008-01-02 00:00:00

abstract：:Most functional neuroimaging techniques rely on activation-flow coupling (AFC) to detect changes in regional brain function, but AFC responses may also be altered during pathophysiological conditions such as ischemia. To define the relationship between progressive ischemia and the AFC response, graded levels of cerebr...

journal_title：Brain research

authors： Burnett MG,Detre JA,Greenberg JH

更新日期：2005-06-14 00:00:00

abstract：:The precursor of the non-Abeta-component of Alzheimer's disease (AD) amyloid (NACP, alpha-synuclein) aggregates into insoluble filaments of Lewy bodies (LBs) in Parkinson's disease (PD) and dementia with LBs (DLB). The microtubule-associated protein tau is an integral component of filaments of neurofibrillary tangles ...

journal_title：Brain research

authors： Arima K,Hirai S,Sunohara N,Aoto K,Izumiyama Y,Uéda K,Ikeda K,Kawai M

更新日期：1999-10-02 00:00:00

abstract：:Projections from the hypothalamus to cells of origin of the greater petrosal nerve were studied by the HRP and autoradiographic techniques in the rat. After an injection of [3H]amino acids into the hypothalamus and an application of HRP to the greater petrosal nerve, we found that a compact group of HRP-labeled neuron...

journal_title：Brain research

authors： Hosoya Y,Matsushita M,Sugiura Y

更新日期：1984-01-02 00:00:00

abstract：:The prefrontal cortex (PFC) plays a central role in preparatory and anticipatory attentional processes. To investigate whether subregions of the PFC play differential roles in these processes we investigated the effect of focal lesions to either lateral prefrontal (lateral PFC; n=11) or orbitofrontal cortex (OFC; n=13...

journal_title：Brain research

authors： Funderud I,Løvstad M,Lindgren M,Endestad T,Due-Tønnessen P,Meling TR,Knight RT,Solbakk AK

更新日期：2013-08-21 00:00:00

abstract：:The effect of L-AP4, a group III mGluR agonist, on sensory synaptic transmission in the lamprey spinal cord has been analyzed. Paired recordings were made between cutaneous mechanosensory neurons (dorsal cells) and postsynaptic spinobulbar giant interneurons. L-AP4 reduced the monosynaptic dorsal cell-evoked EPSP, but...

journal_title：Brain research

authors： Krieger P,El Manira A

更新日期：2002-05-24 00:00:00

abstract：:During a recent study of the effects of photoreceptor degeneration on Muller cells, we observed that unlike glia from normal adult retinas, glia from degenerating rat retinas could be cultured and maintained in vitro for several weeks. Using a variety of cell type specific antisera, we show that at least 70% of cells ...

journal_title：Brain research

authors： Sarthy PV

更新日期：1985-06-24 00:00:00

abstract：:The effect of intraocular injection of the neurotoxin, kainic acid, on the retinofugal pathway has been examined by anterograde transport of horseradish peroxidase. Although less peroxidase was present in all the primary optic centers after the intraocular injection of kainic acid than in the controls, the area occupi...

journal_title：Brain research

authors： Gomez-Ramos P,Perez-Rico C,Reinoso-Suarez F

更新日期：1984-01-09 00:00:00

abstract：:The effects of glucagon like peptide-1 (GLP-1) on reflex swallowing were examined using anaesthetized rats. GLP-1 was injected into the dorsal vagal complex (DVC) using glass micropipettes. Swallowing was induced by repeated electrical stimulation of the central cut end of the superior laryngeal nerve (SLN) and was id...

journal_title：Brain research

authors： Kobashi M,Mizutani S,Fujita M,Mitoh Y,Shimatani Y,Matsuo R

更新日期：2017-09-15 00:00:00

abstract：:A single electrode voltage clamp was used to examine the prolonged hyperpolarizing afterpotential (PHA) which accompanies photoconversion of a substantial fraction of rhodopsin (lambda max = 500 nM) to metarhodopsin (lambda max = 575 nM) in distal photoreceptor cells in the retina of the bay scallop, Pecten irradians....

journal_title：Brain research

authors： Cornwall MC,Gorman AL

更新日期：1982-05-13 00:00:00

abstract：:Choline supplementation of the maternal diet has long-term facilitative effects on spatial and temporal memory processes in the offspring. To further delineate the impact of early nutritional status on brain and behavior, we examined effects of prenatal-choline availability on hippocampal oscillatory frequency bands i...

journal_title：Brain research

authors： Cheng RK,Williams CL,Meck WH

更新日期：2008-10-27 00:00:00

abstract：:Recent researches suggest that autophagic degradation declines with age, and this leads to an accumulation of damage that contributes to age-related cellular dysfunction. Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) shows therapeutic potential for cerebral ischemia in young-adult animals. This study inve...

journal_title：Brain research

authors： Wang P,Lu Y,Han D,Wang P,Ren L,Bi J,Liang J

更新日期：2019-11-15 00:00:00

abstract：:Amyloid deposition, a histopathological feature of Alzheimer's disease brain, may be the underlying cause of this disease. The isolation of enzymes involved in both the normal and aberrant or alternative processing of the beta-amyloid precursor protein may lead to an understanding of how beta-protein, the major compon...

journal_title：Brain research

authors： Razzaboni BL,Papastoitsis G,Koo EH,Abraham CR

更新日期：1992-09-04 00:00:00

abstract：:Ouabain binds to the catalytic subunit of Na+,K+-ATPase and specific [3H]ouabain binding can be used as a measure of the number of active enzyme molecules present in a given tissue. Specific [3H]ouabain binding can be demonstrated in frozen, cryostat sections from rat brain and pineal and these sites have the characte...

journal_title：Brain research

authors： Caspers ML,Schwartz RD,Labarca R,Paul SM

更新日期：1987-04-21 00:00:00

abstract：:To investigate whether differences in vulnerability to free radicals might underlie differences among striatal neurons in their vulnerability to neurodegenerative processes such as occur in ischemia and Huntington's disease, we have analyzed the localization of superoxide free radical scavengers in different striatal ...

journal_title：Brain research

authors： Medina L,Figueredo-Cardenas G,Reiner A

更新日期：1996-02-05 00:00:00