Effects of preoptic injections of gastrin, cholecystokinin, secretin, vasoactive intestinal peptide and PHI on the secretion of luteinizing hormone and prolactin in ovariectomized estrogen-primed rats.

abstract：:This work describes the presence of glucocorticoid binding sites in human temporal cortex obtained following partial lobectomy in two epileptic patients. Using [3H]dexamethasone as radioligand and cold cortisol or RU 28362 as competitor we found an apparent Kd of approximately 2.8 nM with a Bmax of approximately 34 fm...

journal_title：Brain research

authors： Sarrieau A,Dussaillant M,Sapolsky RM,Aitken DH,Olivier A,Lal S,Rostène WH,Quirion R,Meaney MJ

更新日期：1988-02-23 00:00:00

abstract：:The dmy rat is an autosomal recessive mutant that exhibits severe myelin destruction throughout the white matter of the central nervous system. Recently, a point mutation in intron 3 of the Mrs2 has been found in the dmy rat. Mrs2 encodes an essential component of the major electrophoretic Mg(2+) influx system in mito...

journal_title：Brain research

authors： Kuwamura M,Inumaki K,Tanaka M,Shirai M,Izawa T,Yamate J,Franklin RJ,Kuramoto T,Serikawa T

更新日期：2011-05-10 00:00:00

abstract：:Abnormal development of the neocortex is often associated with cognitive deficits and epilepsy. Rodent models are widely used to study normal and abnormal cortical development and have revealed the roles of many important genetic and environmental factors. Interestingly, several inbred mouse strains commonly used in b...

journal_title：Brain research

authors： Lipoff DM,Bhambri A,Fokas GJ,Sharma S,Gabel LA,Brumberg JC,Richfield EK,Ramos RL

更新日期：2011-05-19 00:00:00

abstract：:Corticotropin-releasing factor (CRF) has been hypothesized to be involved in the pathophysiology of anxiety, depression, cognitive and feeding disorders. Two distinct CRF receptor subtypes, CRFR1 and CRFR2, are thought to mediate CRF actions in the CNS. However, the role for each receptor subtype in animal models of n...

journal_title：Brain research

authors： Contarino A,Dellu F,Koob GF,Smith GW,Lee KF,Vale W,Gold LH

更新日期：1999-07-17 00:00:00

abstract：:6-[18F]Fluoro-L-DOPA (FDOPA) is an imaging agent used in the study of dopamine terminals in the living brain using positron emission tomography (PET). To better understand the role of tracer metabolism in dynamic FDOPA PET studies, the pharmacokinetics of individual FDOPA metabolites in extracellular space in the stri...

journal_title：Brain research

authors： DeJesus OT,Haaparanta M,Solin O,Nickles RJ

更新日期：2000-09-15 00:00:00

abstract：:Glutamate is a major neurotransmitter in the CNS. Its release activates NMDA and non-NMDA receptors on the postsynaptic membrane. NMDA receptor activation is shown to be important in physiological and pathological events. The modulatory sites on the NMDA receptor-channel ionophore complex are important in the regulati...

journal_title：Brain research

authors： Saybasili H

更新日期：1998-03-09 00:00:00

abstract：:Three different estrogen receptors (ERs) have been characterized in teleost fish, i.e. Esr1, Esr2a and Esr2b. In this study we carried out in situ hybridizations in the brain and pituitary of the sea bass (Dicentrarchus labrax) to study the putative involvement of Esr2 subtypes in the control of gonadotropin secretion...

journal_title：Brain research

authors： Muriach B,Carrillo M,Zanuy S,Cerdá-Reverter JM

更新日期：2008-05-19 00:00:00

abstract：:Cytochrome P45011B1 (11 beta-hydroxylase) was detected in the brain of male rats by in situ hybridization methods. Normal Sprague-Dawley rats were compared to the transgenic strain TGR(mRen2)27, characterized by the expression of the murine Ren-2d renin gene and the development of severe hypertension. Specific ribopro...

journal_title：Brain research

authors： Erdmann B,Gerst H,Lippoldt A,Bülow H,Ganten D,Fuxe K,Bernhardt R

更新日期：1996-09-09 00:00:00

abstract：:The central amygdaloid nucleus (CeA) receives projection from the parabrachial nucleus (PBN) gustatory neurons and descendingly projects to the PBN, and taste responses in the PBN are significantly affected by stimulation or lesion of the CeA. To examine whether the GABA receptors within the CeA are involved in this m...

journal_title：Brain research

authors： Kang Y,Yan J,Huang T

更新日期：2004-11-26 00:00:00

abstract：:In human brain, regulation of agonist binding to the D2 dopamine receptors by guanine nucleotides is different between several regions. In membranes of the anterior pituitary lobe, agonist binding is fully sensitive to GTP or Gpp(NH)p, whereas it is resistant in membranes of globus pallidus. Both guanine nucleotide-se...

journal_title：Brain research

authors： De Keyser J,Walraevens H,De Backer JP,Ebinger G,Vauquelin G

更新日期：1989-04-10 00:00:00

abstract：:(1) Spreading depression (SD) could be elicited in isolated carp retina by KCI application, the concomitants of which were similar to those described in other vertebrates. (2) The threshold for generating SD was greatly reduced by brief immersion of the retina in low ci-ringer's solutions. The properties of SD waves w...

journal_title：Brain research

authors： Higashida H,Sakakibara M,Mitarai G

更新日期：1977-01-14 00:00:00

abstract：:Routine cell stains disclose abnormal, usually single, nests of ectopic neurons in neocortical layer I of New Zealand Black (NZB) and BXSB autoimmune mice. We have suggested that these anomalies represent only the most visible part of more widespread cortical disorganization. In an attempt to determine the true magnit...

journal_title：Brain research

authors： Sherman GF,Stone JS,Press DM,Rosen GD,Galaburda AM

更新日期：1990-10-08 00:00:00

abstract：:NO performs a wide array of cell signaling functions. Neuronal NO synthase (nNOS) immunoreactivity and nicotinamide adenine dinucleotide phosphate diaphorase (NDP) activity, a marker of nNOS, were concentrated at adult rat neuromuscular junctions and persisted in denervated muscle indicating the localization of the en...

journal_title：Brain research

authors： Kusner LL,Kaminski HJ

更新日期：1996-08-19 00:00:00

abstract：:Neonatal hypoxia-ischemia (HI) has been extensively studied in a rat model characterized by unilateral brain damage (Rice-Vannucci Model). However, as well as in humans, each rat brain hemisphere is distinctly involved in cognitive functions, as for example retrieval of emotionally based memory, and neurochemical asym...

journal_title：Brain research

authors： Arteni NS,Salgueiro J,Torres I,Achaval M,Netto CA

更新日期：2003-05-30 00:00:00

abstract：:The effects of glucose injection into the hepatic portal vein on neural activity of the lateral hypothalamic area (LHA) were studied in rats. A majority of identified glucose-sensitive neurons in the LHA were inhibited by portal injection of glucose. This was found to be mediated through the alpha-noradrenergic pathwa...

journal_title：Brain research

authors： Shimizu N,Oomura Y,Novin D,Grijalva CV,Cooper PH

更新日期：1983-04-11 00:00:00

abstract：:Aquaporin-4 (AQP4), the prominent water channel in the brain, is particularly concentrated in astrocytic endfeet membranes lining the capillaries and the pia. This localisation pattern makes it well suited to regulate the flow of water and the homeostasis of the interstitial fluid surrounding the neurons. Using immuno...

journal_title：Brain research

authors： Medici V,Frassoni C,Tassi L,Spreafico R,Garbelli R

更新日期：2011-01-07 00:00:00

abstract：:We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...

journal_title：Brain research

authors： Uzakov SS,Ivanov AD,Salozhin SV,Markevich VA,Gulyaeva NV

更新日期：2015-10-22 00:00:00

abstract：:(1) Visual, auditory and olfactory input were not necessary for the performance of the lordosis reflex by female rats. Since taste is not involved in this behavior, somatosensory input must be sufficient for triggering the lordosis reflex. (2) Surgical cutaneous denervation markedly reduced the frequency and strength ...

journal_title：Brain research

authors： Kow LM

更新日期：1976-01-09 00:00:00

abstract：:Studies using phorbol esters imply that hippocampal Ca2+ channels are regulated by protein kinase C (PKC); however concerns have been raised because in some circumstances phorbol esters have non-specific effects on ion channels. We have tested the hypothesis that PKC modulates Ca2+ channel activity in hippocampal neur...

journal_title：Brain research

authors： Doerner D,Alger BE

更新日期：1992-11-27 00:00:00

abstract：:Carnosine is a compound of naturally-occurring dipeptide that synthesized by the carnosine synthetase from beta-alanine and l-histidine. Recent reports claim that carnosine plays an important role in the control of epilepsy but its involvement in anticonvulsant functions remains unknown. In this study, we investigated...

journal_title：Brain research

authors： Kozan R,Sefil F,Bağirici F

更新日期：2008-11-06 00:00:00

abstract：:The effect of unilateral basilar papilla removal on glucose uptake in the 2nd and 3rd order auditory nuclei in the chick's brain stem, nucleus magnocellularis and nucleus laminaris, respectively, was examined with [3H]2-deoxy-D-glucose (2-DG) autoradiography. The tissue was processed according to a thaw-mount techniqu...

journal_title：Brain research

authors： Lippe WR,Steward O,Rubel EW

更新日期：1980-08-25 00:00:00

abstract：:The termination of a pathway recently discovered in monkey, from the external cuneate nucleus (ECN) to the thalamus, has been investigated with the degeneration method. A previous HRP study showed that the projection is crossed. The ECN fibers terminate a wedge-shaped zone located dorsally in the rostral half of the c...

journal_title：Brain research

authors： Boivie J,Boman K

更新日期：1981-11-16 00:00:00

abstract：:We have studied magnetic and electrical fields of the brain in normal subjects during the performance of an auditory verbal short-term memory task. On each trial 3 digits, selected from the numbers 'one' through 'nine', were presented for memorization followed by a probe number which could or could not be a member of ...

journal_title：Brain research

authors： Starr A,Kristeva R,Cheyne D,Lindinger G,Deecke L

更新日期：1991-09-06 00:00:00

abstract：:Vasoactive intestinal polypeptide (VIP)-like immunoreactivity in the anterior hypothalamic area (AHA) was studied in 15 bats which are seasonal hibernators, using the unlabeled antibody enzyme method of Sternberger. Our results showed that the density of immunoreactive fibers and terminal plexuses in the AHA was great...

journal_title：Brain research

authors： Laemle LK,Cotter JR

更新日期：1988-02-16 00:00:00

abstract：:The A-ring reduced metabolite of deoxycorticosterone, 3 alpha, 5 alpha-tetrahydrodeoxycorticosterone (THDOC) was recently shown to act at the gamma-aminobutyric acid receptor-chloride ion channel complex in rat brain. The behavioral profile of THDOC was investigated using two animal models of anxiety, the two-chambere...

journal_title：Brain research

authors： Crawley JN,Glowa JR,Majewska MD,Paul SM

更新日期：1986-11-29 00:00:00

abstract：:The cholecystokinin (CCK) concentration in individual brain stem nuclei of rat was determined using the Palkovits punch method19 and the CCK RIA3, CCK has a unique distribution in the brain stem, unlike other neuropeptides and biogenic amines8,19. In general, the CCK levels in the brain stem are 5-20% of rat cerebral ...

journal_title：Brain research

authors： Beinfeld MC,Palkovits M

更新日期：1982-04-22 00:00:00

abstract：:We recently reported that peripheral nerve injury produced by sciatic nerve transection induces a persistent increase in the expression of the immunoreactive Fos protein product of the c-fos proto-oncogene, an indicator of neuronal activity, in the lumbar spinal cord of the rat and that local anesthetic blockade of th...

journal_title：Brain research

authors： Chi SI,Levine JD,Basbaum AI

更新日期：1993-07-23 00:00:00

abstract：:Post traumatic stress disorder (PTSD) is characterised by hyperarousal, anxiety and amnesic symptoms. Deficits in explicit memory recall have been causally related to volume reductions of the hippocampus and prefrontal cortex. While stress-related glucocorticoid secretion appears involved in this apparent atrophy, the...

journal_title：Brain research

authors： Harvey BH,Naciti C,Brand L,Stein DJ

更新日期：2003-09-05 00:00:00

abstract：:In normal adult rats, intense immunostaining for the 75 kDa low-affinity receptor for nerve growth factor and other neurotrophins (p75NGFR) is concentrated in the middle region of the cuneate nucleus (CN), distributed in a blotchy pattern similar to that of cytochrome oxidase (CO) activity. In the adult rats, partial ...

journal_title：Brain research

authors： Foschini DR,Egger MD,Crockett DP

更新日期：1994-05-16 00:00:00

abstract：:Basal sleep amounts in adrenalectomized rats (AdX), as compared to intact animals, exhibit a significant increase in slow-wave sleep (SWS), a tendency towards an increase in paradoxical sleep (PS), and circadian rhythms (SWS and PS) flattened in amplitude. An immobilization stress (IS) of 1 h, imposed on AdX rats at t...

journal_title：Brain research

authors： Bonnet C,Marinesco S,Debilly G,Kovalzon V,Cespuglio R

更新日期：2000-01-24 00:00:00