Kindling of the ventral tegmental area induces supersensitivity in the central dopamine system.

abstract：:Rat hippocampal minces were loaded with [acetyl 1-14C]acetylcholine ([14C]ACh) in the presence of the "poorly penetrating" acetylcholinesterase (EC 3.1.1.7; AChE) inhibitor echothiophate and the effect of high K+ depolarization determined on the subcellular storage and release of [14C]ACh and its metabolites. Results ...

journal_title：Brain research

authors： Carroll PT

更新日期：1996-06-24 00:00:00

abstract：:We have monitored the expression of c-fos protein in the medulla oblongata of the ferret, using immunocytochemistry, to identify the brainstem pathways involved in the mediation of nausea and vomiting caused by the antineoplastic drug cisplatin. Cisplatin administration resulted in c-fos-like immunoreactivity (FLI) in...

journal_title：Brain research

authors： Reynolds DJ,Barber NA,Grahame-Smith DG,Leslie RA

更新日期：1991-11-29 00:00:00

abstract：:Aluminum (Al) is among the most abundant elements on earth, it has been associated with the etiology of Alzheimer's disease. In the present study, AlCl(3) was administered with the dose of 10, 50 or 300 mg/kg b.wt/day through diet for 100 days. On day 101, overnight-fasted animals were sacrificed, the whole brains wer...

journal_title：Brain research

authors： Rui D,Yongjian Y

更新日期：2010-04-09 00:00:00

abstract：:The neocortex in chronically prepared rats is very resistant to the induction of long-term potentiation (LTP). In the first of two experiments described in this paper, we tried unsuccessfully to induce neocortical LTP within one session by coactivating basal forebrain cholinergic and cortical inputs to our neocortical...

journal_title：Brain research

authors： Racine RJ,Chapman CA,Trepel C,Teskey GC,Milgram NW

更新日期：1995-12-08 00:00:00

abstract：:The purposes of this study were to examine responses of superficial (depth <300 microm) and deeper thoracic spinal neurons to chemical stimulation of cardiac afferents and effects of descending influences on these neurons. Extracellular potentials of single T(3)-T(4) neurons were recorded in pentobarbital anesthetized...

journal_title：Brain research

authors： Qin C,Chandler MJ,Miller KE,Foreman RD

更新日期：2003-01-03 00:00:00

abstract：:Rabbits reared from birth in stroboscopic illumination have no experience of visual motion. In primary visual cortex of these animals there is a large reduction in the number of cells which are direction selective. This result, contrary to previous reports, shows that the rabbit visual system can be modified by early ...

journal_title：Brain research

authors： Pearson HE,Berman N,Murphy EH

更新日期：1981-01-01 00:00:00

abstract：:The ability of midbrain raphe (MR) cells grafted into serotonin-depleted brain to restore hippocampal responses to synaptically released serotonin was studied using a serotonin-releasing drug, D-fenfluramine (FFA). In normal rats, FFA enhances reactivity of the dentate gyrus (DG) to perforant-path stimulation, while s...

journal_title：Brain research

authors： Richter-Levin G,Segal M

更新日期：1990-06-25 00:00:00

abstract：:Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with deficits in fluid reasoning, which may be related to self-regulation of cognition and behavior, and requires intact attention, working memory, and inhibition skills. No functional magnetic resonance imaging (fMRI) studies have directly examined fluid r...

journal_title：Brain research

authors： Tamm L,Juranek J

更新日期：2012-07-17 00:00:00

abstract：:The mesocorticolimbic circuitry has been implicated in the pathophysiology of several neuropsychiatric syndromes like chronic pain and addiction. The aim of this study was to evaluate the effects of dizocilpine (MK-801), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, on sensorimotor behaviors and t...

journal_title：Brain research

authors： Al-Amin HA,Saadé NE,Khani M,Atweh S,Jaber M

更新日期：2003-08-15 00:00:00

abstract：:Metabolites formed from testosterone in the brain, their neuroanatomical distribution and the kinetic properties of the enzymes were studied in male and female Japanese quail chicks and compared with the adult brain using an in vitro radioassay. Oestradiol-17 beta. 5 alpha-dihydrotestosterone, 5 beta-dihydrotestostero...

journal_title：Brain research

authors： Hutchison JB,Schumacher M

更新日期：1986-02-01 00:00:00

abstract：:Alteration of blood-brain barrier (BBB) permeability by 2450 MHz CW microwaves was assessed semi-quantitatively after intravenous injection of horseradish peroxidase (HRP) and exposure of conscious, unrestrained rats to incident power densities of 0, 20 or 65 mW/cm2 for 30, 90 or 180 min. Additional rats were exposed ...

journal_title：Brain research

authors： Williams WM,Del Cerro M,Michaelson SM

更新日期：1984-05-01 00:00:00

abstract：:We found that local perfusion of COA-Cl (0.1, 0.4, or 1.0 mM) into the dorsal striatum of living mice produced a significant and dose-dependent increase in extracellular DA levels, with the highest dose of 1.0 mM COA-Cl producing an approximately 5-fold increase in DA. Consistent with in vivo findings, 0.1 and 0.2 mM ...

journal_title：Brain research

authors： Jamal M,Tsukamoto I,Takata M,Ito A,Tanaka N,Miki T,Takakura A,Ameno K,Kubota Y,Konishi R,Kinoshita H

更新日期：2019-03-01 00:00:00

abstract：:Several studies have examined the activity of neurons in hypothalamic tissue slices. The present experiments studied relationships between neuronal activity (firing rate and thermosensitivity) and tissue survival as a function of time and slice thickness. Rat hypothalamic tissue slices were sectioned at different thic...

journal_title：Brain research

authors： Burgoon PW,Burry RW,Boulant JA

更新日期：1997-11-28 00:00:00

abstract：:Insulin-like 6 immunoreactivity (irINSL6) was detected in Leydig cells of the mouse testis. In the brain, labeled somata were detected mainly in the caudal hypothalamus and midbrain. Double labeling the brainstem sections revealed that irINSL6 somata were 5-hydroxytryptamine (5-HT) positive. The presence of irINSL6 in...

journal_title：Brain research

authors： Brailoiu GC,Dun SL,Yin D,Yang J,Chang JK,Dun NJ

更新日期：2005-04-08 00:00:00

abstract：:The enzymatic and regulatory properties of Ca2+/calmodulin-dependent protein kinase in the postsynaptic density (mPSDp CaM kinase) of the rat forebrain was compared with those of soluble Ca2+/calmodulin-dependent protein kinase II (CaM kinase II). mPSDp CaM kinase was different from soluble CaM kinase II in terms of s...

journal_title：Brain research

authors： Ochiishi T,Sugiura H,Yamauchi T

更新日期：1993-04-30 00:00:00

abstract：:The effects of VIP and of peptides of the VIP family: secretin, glucagon, the porcine histidine isoleucine containing peptide (PHI) and the rat hypothalamic growth hormone-releasing hormone (rhGRF) on the cyclic AMP and inositol phosphate contents of isolated rat superior cervical ganglia were investigated. We demonst...

journal_title：Brain research

authors： Audigier S,Barberis C,Jard S

更新日期：1986-06-25 00:00:00

abstract：:The anatomical localization of nociceptin receptors was examined by in vitro quantitative autoradiography techniques in rat spinal cord sections by using [(125)I-Tyr(14)]nociceptin. [(125)I-Tyr(14)]nociceptin appeared to interact with a single class of binding sites (K(D)=0.1 nM) present in the grey matter in all lami...

journal_title：Brain research

authors： Gouardères C,Tafani JA,Meunier JC,Jhamandas K,Zajac JM

更新日期：1999-08-14 00:00:00

abstract：:The effect of intracerebroventricular administration of dizocilpine on feeding behaviour and adrenal corticrotropic hormone (ACTH)-induced anorexia in elevated plus maze was examined. Dizocilpine (10, 20 and 40 nmol/rat, i.c.v.) showed a dose-dependent increase in food intake in 16 h food deprived rats. Dopamine recep...

journal_title：Brain research

authors： Ninan I,Kulkarni SK

更新日期：1998-11-23 00:00:00

abstract：:The effects of acute and chronic phencyclidine (PCP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in discrete regions of rat brain. Both acute and chronic administration of PCP induced high locomotor activity, stereotypy and ataxia. On PCP administration, NTLI decreased significantly in...

journal_title：Brain research

authors： Wachi M,Okuda M,Togashi S,Fuwano S,Miyashita O

更新日期：1985-05-06 00:00:00

abstract：:A new quantitative staining technique for the assay of protein in tissue sections using the dye Coomassie brilliant blue G 250 is discussed. This densitometric procedure uses commercially available hardware and software employed in the quantitation of receptor autoradiographs. Rather than assuming a homogeneous distri...

journal_title：Brain research

authors： Miller JA,Curella P,Zahniser NR

更新日期：1988-04-26 00:00:00

abstract：:Luteinizing hormone (LH) secretion during the reproductive cycle and in ovariectomized (OVX) rats is pulsatile and this pattern of secretion is determined by intermittent discharges of LH-releasing hormone (LHRH) into the hypophysial portal vessels. LHRH secretion is probably controlled by prior pulsatile norepinephri...

journal_title：Brain research

authors： Anselmo-Franci JA,Rocha-Barros VM,Franci CR,McCann SM

更新日期：1999-06-26 00:00:00

abstract：:In the cat, cells of the superior colliculus (SC) and the tectofugal pathways of the visual system are highly selective for the direction of a moving visual stimulus. Deep layer units of SC in addition respond to auditory and somatosensory stimuli, but the proportion of such non-visual cells is usually found to be muc...

journal_title：Brain research

authors： Rauschecker JP,Harris LR

更新日期：1989-06-19 00:00:00

abstract：:In this study we investigated the functional connectivity in 23 Mild TBI (mTBI) patients with and without memory complaints using resting state fMRI in the sub-acute stage of injury as well as a group of control participants. Results indicate that mTBI patients with memory complaints performed significantly worse than...

journal_title：Brain research

authors： Sours C,Zhuo J,Janowich J,Aarabi B,Shanmuganathan K,Gullapalli RP

更新日期：2013-11-06 00:00:00

abstract：:The visual system in the pigeon is composed of the tectofugal, thalamofugal and accessory optic pathways. Though their anatomy and physiology have been extensively studied, the functional interactions between these pathways are largely unknown. The present study shows by using multiple electrophysiological techniques ...

journal_title：Brain research

authors： Cao P,Yang Y,Yang Y,Wang SR

更新日期：2006-01-19 00:00:00

abstract：:Large neurons in the neostriatum of patients with Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) were investigated topographically, histologically and ultrastructurally. The number of large neurons whose nuclear area is greater than 101 microns2 was uniformly decreased in the neostriatum in PSP, but...

journal_title：Brain research

authors： Oyanagi K,Takahashi H,Wakabayashi K,Ikuta F

更新日期：1991-03-29 00:00:00

abstract：:Stimulation of spinal serotonin (5-HT)(2A/2C) receptors has previously been reported to lead to either a pro-nociceptive or an anti-nociceptive response. Behavioral data have indicated that the pro-nociceptive effect is related to the release of substance P (SP). The aim of this in vivo microdialysis study was to inve...

journal_title：Brain research

authors： Kjørsvik Bertelsen A,Warsame Afrah A,Gustafsson H,Tjølsen A,Hole K,Stiller CO

更新日期：2003-10-10 00:00:00

abstract：:Intracellular recordings from locus coeruleus neurons grown in explant cultures reveal age-related differences in the responses to iontophoretically applied noradrenaline. Cells grown in culture for more than 26 days exhibit a simple hyperpolarizing response while cells cultured for less than 26 days often have biphas...

journal_title：Brain research

authors： Finlayson PG,Marshall KC

更新日期：1986-03-01 00:00:00

abstract：:Brain/kidney (B/K) protein is a new protein of 474 amino acids, which contains two C2 domains structurally homologous to those present in synaptotagmins. The expression of B/K protein was identified in the rat retina and B/K protein immunoreactivity was localized to a number of ganglion cells, a few amacrine cells and...

journal_title：Brain research

authors： Kwon OJ,Ju WK,Choi SH,Lee MY,Oh SJ,Chun MH

更新日期：2000-03-31 00:00:00

abstract：:The carrier-mediated uptake of anionic and cationic amino acids by the basolateral face (blood side) of the isolated perfused sheep choroid plexus was demonstrated using the paired-tracer dilution technique. The uptake of these two classes of amino acid was higher than at the blood-brain barrier with no cross-competit...

journal_title：Brain research

authors： Preston JE,Segal MB

更新日期：1992-05-29 00:00:00

abstract：:Chronic total sleep deprivation (TSD) of rats by the disk-over-water method reliably produces initial increases and subsequent decreases in waking intraperitoneal (Tip) and hypothalamic (Thy) temperatures, progressive increases in energy expenditure, skin lesions on the tail and plantar surfaces, debilitated appearanc...

journal_title：Brain research

authors： Feng PF,Bergmann BM,Rechtschaffen A

更新日期：1995-12-12 00:00:00