Abstract：
:Photic information that entrains circadian rhythms is transmitted to the suprachiasmatic nucleus (SCN) from the retina and from the retinorecipient intergeniculate leaflet (IGL). Expression of light-induced Fos protein in SCN neurons is correlated with the effectiveness of such light to induce phase shifts, and is prevented by pretreatment with glutamate receptor antagonists that prevent phase shifts as well. In the present study we demonstrate that treatments with N-methyl-d-aspartate (NMDA) and non-NMDA receptor antagonists prior to light pulses during the subjective night have no effect on light-induced Fos immunoreactivity (Fos-IR) in IGL neurons despite attenuating Fos-IR in the SCN. Transmission of photic information along retinogeniculate and retinohypothalamic pathways appears to be mediated by different mechanisms.
journal_name
Brain Resjournal_title
Brain researchauthors
Edelstein K,Amir Sdoi
10.1016/s0006-8993(98)00911-1subject
Has Abstractpub_date
1998-11-09 00:00:00pages
264-8issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(98)00911-1journal_volume
810pub_type
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