Abstract：
:Bradykinin is known to rapidly elevate intracellular calcium leading to secretion of neurotransmitters and short term activation of tyrosine hydroxylase (TH). In this study we examined the effect of bradykinin on mRNA levels of two catecholamine biosynthetic enzymes. Treatment of PC12 cells with 1 microM bradykinin for 3 h markedly elevated both TH and dopamine beta-hydroxylase (DBH) mRNA levels.
journal_name
Brain Resjournal_title
Brain researchauthors
Gebreyesus K,Kilbourne EJ,Sabban ELdoi
10.1016/0006-8993(93)91477-asubject
Has Abstractpub_date
1993-04-16 00:00:00pages
345-8issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(93)91477-Ajournal_volume
608pub_type
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