Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles.

abstract：:Previous studies in our laboratory using rat brain tissue have shown that neuropeptide Y (NPY) can enhance NMDA- and potassium-stimulated dopamine release from various brain regions and that this enhancement is reversed by sigma (sigma) receptor antagonists. In the current study, we sought to determine whether SH-SY5Y...

journal_title：Brain research

authors： Ault DT,Werling LL

更新日期：2000-09-22 00:00:00

abstract：:MabQ155, a monoclonal antibody against synaptophysin, has been used to conduct a light microscopic survey of synaptogenesis in the suprachiasmatic nucleus of the perinatal rat. Synaptophysin is an integral component of synaptic vesicle membranes which is expressed in growth cones and growth cone filopodia as well as i...

journal_title：Brain research

authors： Laemle LK,Repke KB,Hawkes R,Rice FL

更新日期：1991-03-22 00:00:00

abstract：:Focal electrical stimulation and glutamate microinjection in the nuclei reticularis gigantocellularis (NGC) and gigantocellularis pars alpha (NGC alpha) both inhibit the nociceptive tail-flick (TF) reflex in rats. The present experiments were undertaken to determine the transmitter(s) at the level of the lumbar spinal...

journal_title：Brain research

authors： Zhuo M,Gebhart GF

更新日期：1990-12-03 00:00:00

abstract：:Nestin is an intermediate filament protein, transiently and abundantly expressed early in embryogenesis, e.g., in neuroepithelial cells, radial glia, germinal matrix cells and vascular cells. In the adult rat brain, nestin is only present in endothelial and select subventricular cells. We tested the hypothesis that af...

journal_title：Brain research

authors： Li Y,Chopp M

更新日期：1999-08-14 00:00:00

abstract：:Time-course expression of Bax and Bcl-2 proteins, identified as apoptosis-regulating molecules, was assessed in gerbil hippocampus following transient forebrain ischemia. Brain sections from animals sacrificed at 48, 72, 96 h and 7 days following 5 min ischemia were immunohistochemically evaluated using polyclonal ant...

journal_title：Brain research

authors： Hara A,Iwai T,Niwa M,Uematsu T,Yoshimi N,Tanaka T,Mori H

更新日期：1996-03-04 00:00:00

abstract：:The effect of immunoneutralization of hypothalamic neuropeptide Y (NPY) on food intake was examined to clarify the involvement of NPY in the control mechanism of feeding behavior. Injection of anti-NPY gamma-globulin into the bilateral hypothalamic paraventricular nuclei of 24-h food-deprived rats significantly inhibi...

journal_title：Brain research

authors： Shibasaki T,Oda T,Imaki T,Ling N,Demura H

更新日期：1993-01-22 00:00:00

abstract：:This study has presented cells, fibers and non-neuronal elements as seen in 3 dimensions using the SEM. Our discussion on possible artifacts which can occur with this method is offered in the hope that others will develop better techniques of dissection and specimen preparation. With the picture of normal tissue in mi...

journal_title：Brain research

authors： Paul LA,Fried I,Scheibel AB

更新日期：1984-12-01 00:00:00

abstract：:The neuropeptide nociceptin/orphanin FQ (N/OFQ) and its receptor are members of the endogenous opioid peptide family. In mammals N/OFQ modulates a variety of biological functions such as nociception, food intake, endocrine, control of neurotransmitter release, among others. In the molluscs Cepea nemoralis and Helix as...

journal_title：Brain research

authors： León-Olea M,Miller-Pérez C,Sánchez-Islas E,Mendoza-Sotelo J,Garduño-Gutiérrez R,de Gortari P,Amaya MI

更新日期：2013-04-10 00:00:00

abstract：:Myelin basic proteins (MBP) obtained from bovine, guinea pig and human nervous tissues exhibited hemagglutinating activity for erythrocytes of several animal species. The activity to each erythrocyte was actually equal among the 3 MBPs. With bovine MBP and chicken erythrocytes, the hemagglutinating activity did not re...

journal_title：Brain research

authors： Ikeda K,Yamamoto T

更新日期：1985-03-11 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a family of neurotrophins that plays crucial roles in neural development, survival, maintenance and regeneration both in central and peripheral nervous systems. To examine the effects of BDNF on mastication, jaw movement trajectories and masticatory muscle activities were el...

journal_title：Brain research

authors： Okayasu I,Yamada Y,Maeda T,Yoshida N,Koga Y,Oi K

更新日期：2004-07-30 00:00:00

abstract：:Opioid antagonists block the positive hedonic response to food taste and are potent inhibitors of palatability-driven feeding. However, the specific brain regions within which opioid peptide secretion contributes to the maintenance of palatability-driven feeding have not been clearly established. In the present study,...

journal_title：Brain research

authors： Park TH,Carr KD

更新日期：1998-09-14 00:00:00

abstract：:Adult male rats, intact (N) or with complete (CHD), anterior (AHD), or posterior (PHD) hypothalamic deafferentations were bilaterally adrenalectomized. At 3, 6, 12 and 20 days post-adrenalectomy they were decapitated and trunk blood was collected for ACTH determinations. In N rats, ACTH markedly elevated up to 850 pg/...

journal_title：Brain research

authors： Weidenfeld J,Siegel RA,Conforti N,Chowers I,Feldman S

更新日期：1984-11-26 00:00:00

abstract：:Aluminum (Al) is among the most abundant elements on earth, it has been associated with the etiology of Alzheimer's disease. In the present study, AlCl(3) was administered with the dose of 10, 50 or 300 mg/kg b.wt/day through diet for 100 days. On day 101, overnight-fasted animals were sacrificed, the whole brains wer...

journal_title：Brain research

authors： Rui D,Yongjian Y

更新日期：2010-04-09 00:00:00

abstract：:The phenomenon of ischemic tolerance has been closely associated with the expression of heat shock proteins but recently, stress tolerance not related to hsp72 has been reported. In the present study, we focused on ischemic tolerance induced by hypoxia and hyperthermia in neonatal rat brain and analyzed the expression...

journal_title：Brain research

authors： Wada T,Kondoh T,Tamaki N

更新日期：1999-11-20 00:00:00

abstract：:We examined how adjective ordering is used in language comprehension by crossing order preference and concreteness in phrases consisting of two adjectives and a noun. We used both more typical phrases in which the preferred order has a concrete second adjective ("exhaustive hardback encyclopedia") and those with a con...

journal_title：Brain research

authors： Huang HW,Federmeier KD

更新日期：2012-09-26 00:00:00

abstract：:The aim of this work was to characterize the interaction of the Na+-channel toxin, purified from venom of the scorpion Leiurus quinquestriatus, with microtubule proteins in vitro. The toxin enhanced microtubule assembly, causing the formation of microtubule 'bundles'. It interacted with the Na+-channel 270 kDa subunit...

journal_title：Brain research

authors： Hargreaves AJ,Montejo de Garcini E,Avila J

更新日期：1986-07-01 00:00:00

abstract：:The effect of high concentrations of L-ascorbic acid on the in vivo and in vitro growth of human neuroblastoma has been investigated. Directly implemented into cell culture it decreased the DNA, RNA and protein synthesis, and mitosis of neuroblastoma cells, without affecting normal neuronal cells. In vivo treatment of...

journal_title：Brain research

authors： Pavelić K

更新日期：1985-09-09 00:00:00

abstract：:Murine urocortin 3 (mUcn 3), a member of the corticotropin releasing factor (CRF) peptide family, was recently identified. Of known agonists, this neuropeptide displays the highest degree of selectivity in binding to the CRF(2) receptor. These experiments sought to test the hypothesis that CRF(2) receptors have a role...

journal_title：Brain research

authors： Valdez GR,Zorrilla EP,Rivier J,Vale WW,Koob GF

更新日期：2003-08-08 00:00:00

abstract：:Studies were conducted to assess whether stimulation of dopamine receptors located in the globus pallidus might play a role in mediating the enhanced pallidal activity seen after systemic administration of dopamine agonists or D-amphetamine. Dopamine, applied iontophoretically, had modest effects on the activity of pa...

journal_title：Brain research

authors： Bergstrom DA,Walters JR

更新日期：1984-09-17 00:00:00

abstract：:Brain-derived angiotensin II (ANG II) and prostaglandins have important roles in the regulation of body fluid and blood pressure homeostasis. In the present studies we investigated the central interactions between these two neurochemical products in regulating the hypothalamo-neurohypophysial system during dehydration...

journal_title：Brain research

authors： Kadekaro M,Terrell ML,Bui V,Summy-Long JY

更新日期：2001-01-19 00:00:00

abstract：:Two experiments were undertaken to investigate dopaminergic involvement in the local rate of responding on a fixed ratio 5 (FR5) instrumental lever pressing schedule. Rats were trained to press a lever for food reinforcement on a FR5 schedule, and a computer program was used to record the interresponse time (IRT) for ...

journal_title：Brain research

authors： Salamone JD,Kurth PA,McCullough LD,Sokolowski JD,Cousins MS

更新日期：1993-11-19 00:00:00

abstract：:We previously reported that glial fibrillary acidic protein (GFAP) levels increased significantly at 3 days after stab wounds, relative to sham-operated controls, reaching a maximum of 200% of control value at 5-7 days. They then fell to near-normal values by 21 days. To determine whether these protein changes correla...

journal_title：Brain research

authors： Hozumi I,Aquino DA,Norton WT

更新日期：1990-11-26 00:00:00

abstract：:Chemokine receptors, and in particular CXCR4 and CCR5 play a key role in the neuropathogenesis of Human Immunodeficiency Virus-1 (HIV)4 associated dementia (HAD). Thus, new insight into the expression of CXCR4 in the central nervous system may help develop therapeutic compounds against HAD. Brain-derived neurotrophic ...

journal_title：Brain research

authors： Ahmed F,Tessarollo L,Thiele C,Mocchetti I

更新日期：2008-08-28 00:00:00

abstract：:Single unit activities of Y, X and W cells were recorded in the cat lateral geniculate nucleus to study how their responses to stationary light spots change with the cortical EEG. The shift from desynchronized to synchronized EEG drastically suppressed W cell activities, depressed both transient and sustained componen...

journal_title：Brain research

authors： Sawai H,Morigiwa K,Fukuda Y

更新日期：1988-07-12 00:00:00

abstract：:To elucidate the intracellular mechanism of seizure discharge, phosphorylation of cellular protein during pentylenetetrazole (PTZ)-induced bursting activity in snail neurons was investigated. PTZ markedly enhanced the phosphorylation of proteins of 34,000 and 50,000 molecular weight. Similar effects were observed by a...

journal_title：Brain research

authors： Onozuka M,Imai S,Sugaya E

更新日期：1986-01-01 00:00:00

abstract：:(1) The possibility that water intake elicited by the administration of angiotensin-II to the preoptic region (POA), subfornical organ and anterior third ventricle is mediated by separate neural systems was investigated in 58 male Wistar rats using electrolytic lesion techniques. (2) Lesions of the midlateral hypothal...

journal_title：Brain research

authors： Kucharczyk J,Assaf SY,Mogenson GJ

更新日期：1976-05-28 00:00:00

abstract：:GEC1 protein shares high identity with GABARAP (GABA(A) Receptor-Associated Protein), interacts with tubulin and GABA(A) receptors and is potentially involved in intracellular transport processes. Recently, using quantitative real time PCR, we have reported the gec1 mRNA expression in different rat brain areas. In the...

journal_title：Brain research

authors： Tolle F,Risold PY,Mansuy-Schlick V,Rossi E,Boyer-Guittaut M,Fraichard A,Jouvenot M

更新日期：2008-05-19 00:00:00

abstract：:Alzheimer's disease (AD) classically presents with gray matter atrophy, as well as feature significant white matter abnormalities. Previous evidence indicates the overall burden of these pathological changes continues to advance as the disease progresses. The aim of this study was to investigate whether pathological a...

journal_title：Brain research

authors： Kitamura S,Kiuchi K,Taoka T,Hashimoto K,Ueda S,Yasuno F,Morikawa M,Kichikawa K,Kishimoto T

更新日期：2013-06-17 00:00:00

abstract：:At various times after spinal nerve injury, dorsal root ganglia (DRGs) from injured segments were removed with attached dorsal roots and spinal nerves. In an in vitro recording chamber, spontaneously active units were recorded from teased dorsal root fascicles. Sustained spontaneous activity could first be recorded at...

journal_title：Brain research

authors： Liu X,Chung K,Chung JM

更新日期：1999-12-04 00:00:00

abstract：:The effects of VIP and of peptides of the VIP family: secretin, glucagon, the porcine histidine isoleucine containing peptide (PHI) and the rat hypothalamic growth hormone-releasing hormone (rhGRF) on the cyclic AMP and inositol phosphate contents of isolated rat superior cervical ganglia were investigated. We demonst...

journal_title：Brain research

authors： Audigier S,Barberis C,Jard S

更新日期：1986-06-25 00:00:00