Abstract:
:The effects of VIP and of peptides of the VIP family: secretin, glucagon, the porcine histidine isoleucine containing peptide (PHI) and the rat hypothalamic growth hormone-releasing hormone (rhGRF) on the cyclic AMP and inositol phosphate contents of isolated rat superior cervical ganglia were investigated. We demonstrate that VIP is able to provoke a large inositol lipid breakdown by acting directly on ganglionic cells. This observation suggests the presence in rat superior cervical ganglia of a new type of receptors for VIP or for an unidentified peptide structurally related to VIP.
journal_name
Brain Resjournal_title
Brain researchauthors
Audigier S,Barberis C,Jard Sdoi
10.1016/0006-8993(86)90200-3subject
Has Abstractpub_date
1986-06-25 00:00:00pages
363-7issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)90200-3journal_volume
376pub_type
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