GABAergic ganglion cells in the rabbit retina.

abstract：:Acute hyperammonemia is associated with motor disturbances that are thought to involve striatal dopaminergic dysfunction. Discharge of striatal dopaminergic neurons is controlled by N-methyl-D-aspartate (NMDA) receptors, the excessive activation of which contributes to ammonia neurotoxicity. Here we show that ammonium...

journal_title：Brain research

authors： Anderzhanova E,Oja SS,Saransaari P,Albrecht J

更新日期：2003-07-11 00:00:00

abstract：:Neural activity was recorded from 218 sites in the striatum (caudate-putamen and nucleus accumbens) of rats trained on a lever-release version of the conditioned avoidance response (CAR) task, in which an auditory signal elicits a short-latency, forelimb withdrawal. > 80% of these recording sites showed task-related a...

journal_title：Brain research

authors： White IM,Rebec GV

更新日期：1993-07-09 00:00:00

abstract：:The distribution and relative specificity of cholecystokinin (CCK) receptors in the rat brain was mapped by in vitro autoradiography with [125I]CCK-33. We identified two distinct binding patterns, suggesting two CCK receptor types. The first is widespread and relatively non-specific. The second, localized to a few sub...

journal_title：Brain research

authors： Moran TH,Robinson PH,Goldrich MS,McHugh PR

更新日期：1986-01-01 00:00:00

abstract：:In animal models, the hallmark of a hypoxic condition is a strong negative shift of the DC potential (anoxic terminal negativity, ATN). This DC-shift is interpreted to be primarily due to a breakdown of the membrane potential of neurons. Such massive neuronal depolarizations have not been reported for all human neocor...

journal_title：Brain research

authors： Köhling R,Schmidinger A,Hülsmann S,Vanhatalo S,Lücke A,Straub H,Speckmann EJ,Tuxhorn I,Wolf P,Lahl R,Pannek H,Oppel F,Greiner C,Moskopp D,Wassmann H

更新日期：1996-11-25 00:00:00

abstract：:The fine structure of reaggregating cultures of cells from 6- to 7-day-old mouse cerebellum was studied at intervals between 3 and 21 days in vitro (DIV). The resulting aggregates consisted mainly of small neurons (granule, stellate and basket cells), neuroglial cells and their processes. Large neurons were rarely pre...

journal_title：Brain research

authors： Orkand PM,Lindner J,Schachner M

更新日期：1984-09-01 00:00:00

abstract：:We monitored the protein expression profiles of collapsin response mediator protein 2 and 4 (CRMP2 and CRMP4) throughout cat primary visual area 17 at different postnatal ages. Single immunocytochemical stainings revealed a clear effect of cortical maturation on the spatial and laminar distribution profile of CRMP2 an...

journal_title：Brain research

authors： Cnops L,Hu TT,Burnat K,Van der Gucht E,Arckens L

更新日期：2006-05-09 00:00:00

abstract：:We investigated the effect of adenosine A1 receptors on the release of acetylcholine (ACh) and GABA, and on the intracellular calcium concentration ([Ca2+]i) response in cultured chick amacrine-like neurons, stimulated by KCl depolarization. The KCl-induced release of [3H]ACh, but not the release of [14C]GABA, was pot...

journal_title：Brain research

authors： Santos PF,Caramelo OL,Carvalho AP,Duarte CB

更新日期：2000-01-03 00:00:00

abstract：:The distribution of retinotectal afferents has been studied by autoradiography in 4 adult cats. The findings suggest that crossed and uncrossed retinal fibers terminate in a striking cluster-and-sheet pattern that varies systematically with respect to the retinotopic map of the colliculus. Following unilateral eye inj...

journal_title：Brain research

authors： Graybiel AM

更新日期：1975-10-10 00:00:00

abstract：:It has been well established that the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) opener, diazoxide, has protective effects on the heart and brain following ischemia/reperfusion injury. However, the mechanism of the neuroprotective effects of diazoxide remains unclear. This study highlights the anti-apo...

journal_title：Brain research

authors： Zhang H,Wang ZQ,Zhao DY,Zheng DM,Feng J,Song LC,Luo Y

更新日期：2011-01-25 00:00:00

abstract：:Tetanization of commissural-CA1 input to the apical dendrites of the dorsal hippocampal CA1 area was found to produce a marked long-term potentiation of the field EPSP. Whereas by concurrent tetanization of the commissural pathway and medial septo-CA1 input, this potentiation was significantly reduced. Thus a negative...

journal_title：Brain research

authors： Xie XP

更新日期：1988-04-05 00:00:00

abstract：:The effects of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS), a synthetic precursor of norepinephrine (NE), on the long-term potentiation (LTP) in the hippocampal mossy fiber-CA3 system was examined in urethane-anesthetized rats, the objective being to determine whether or not this drug acts as NE on the LTP. L-thr...

journal_title：Brain research

authors： Sakai N,Sasa M,Ishihara K,Komure O,Tanaka C,Takaori S

更新日期：1991-12-20 00:00:00

abstract：:Intracellular recordings were made from rabbit nodose ganglion cells in vitro. Morphine (up to 100 micro M), normorphine (up to 10 micro M) and D-Ala2, Leu5-enkephalin (DADLE) (up to 5 micro M) each had no detectable effect on the electrical properties of the cell membrane, except for local anesthetic-like actions at ...

journal_title：Brain research

authors： Shefner SA,North RA,Zukin RS

更新日期：1981-09-21 00:00:00

abstract：:The effect of MK-801 on striatal dopamine (DA) release was investigated by using an in vivo microdialysis technique in the freely moving rat. Systemic injection of MK-801 (0.25, 0.5, 1, 2 mg/kg, i.p.) reduced the extracellular level of DA significantly and produced no change in the level of 3,4-dihydroxyphenylacetic a...

journal_title：Brain research

authors： Kashihara K,Hamamura T,Okumura K,Otsuki S

更新日期：1990-09-24 00:00:00

abstract：:The neuronal mechanisms of sneezing were examined in precollicular-postmammillary decerebrate cats. Mechanical stimulation (frequency 20 Hz, peak-to-peak displacement 0.5 mm) of the nasal membrane evoked a series of sneezes. In the same preparation, electrical stimulation (duration 0.2 ms, frequency 10 Hz, 5-50 microA...

journal_title：Brain research

authors： Nonaka S,Unno T,Ohta Y,Mori S

更新日期：1990-03-19 00:00:00

abstract：:The present paper examines the hypothesis that the long latency EMG activity produced by muscle stretch is the result of long loop reflex pathways involved in the control of limb stiffness. We recorded the cerebral responses and late EMG activity in agonist and antagonist muscles following sudden stretch of the wrist ...

journal_title：Brain research

authors： Goodin DS,Aminoff MJ

更新日期：1992-08-28 00:00:00

abstract：:The distribution of carnosine-like immunoreactivity in photoreceptors of the frog retina was studied by post-embedding electron microscope immunocytochemistry. Different fixation and embedding procedures were applied and the best results were achieved on sections from tissue embedded in the hydrophilic resin LR White....

journal_title：Brain research

authors： Pognetto MS,Cantino D,Fasolo A

更新日期：1992-04-24 00:00:00

abstract：:Motoneuron phenotype in the spinal cord is regulated by an intrinsic genetic program, extrinsic environmental signals and target-derived molecules. Axonal lesions trigger a phenotype switch to foster repair phenomena and axonal re-growth. We have investigated the influence of the long-term treatment with thyroid hormo...

journal_title：Brain research

authors： Giardino L,Giuliani A,Bettelli C,Calzà L

更新日期：2002-01-25 00:00:00

abstract：:The present study was designed to evaluate the sleep pattern of rats submitted to chronic stressors (restraint, electrical footshock, swimming and cold) applied to male rats. After 48 h-baseline recording, rats were submitted to 4 days of chronic stress, and electrocorticogram recordings were carried out continuously....

journal_title：Brain research

authors： Papale LA,Andersen ML,Antunes IB,Alvarenga TA,Tufik S

更新日期：2005-10-26 00:00:00

abstract：:The central myelin sheaths of the recessive autosomal mutant mouse, Shiverer, were investigated by electron microscopy with special reference to the pattern of myelin formation. The results obtained may be summarized as follows: (1) the major dense line of myelin lamellae generally failed to be formed, but the axons w...

journal_title：Brain research

authors： Inoue Y,Nakamura R,Mikoshiba K,Tsukada Y

更新日期：1981-08-24 00:00:00

abstract：:The effect of intraocular injection of the neurotoxin, kainic acid, on the retinofugal pathway has been examined by anterograde transport of horseradish peroxidase. Although less peroxidase was present in all the primary optic centers after the intraocular injection of kainic acid than in the controls, the area occupi...

journal_title：Brain research

authors： Gomez-Ramos P,Perez-Rico C,Reinoso-Suarez F

更新日期：1984-01-09 00:00:00

abstract：:Platelet-derived growth factor-B (PDGF-B) is a growth factor that regulates cell migration, proliferation, and differentiation, and is involved in several physical and pathological processes. The overexpression of PDGF-B in glioma surgical samples revealed its effect on tumorigenesis. In this study, we determined that...

journal_title：Brain research

authors： Zhou Y,Jin G,Mi R,Dong C,Zhang J,Liu F

更新日期：2014-03-27 00:00:00

abstract：:The dorsal column and its nuclei exhibit a considerable number of fibers containing neuropeptides, such as calcitonin gene-related peptide (CGRP) and substance P (SP), whose origins and functional roles are as yet unknown. The present study attempts to determine the origin and nature of these fibers by means of immuno...

journal_title：Brain research

authors： Tamatani M,Senba E,Tohyama M

更新日期：1989-08-21 00:00:00

abstract：:The importance of particular genes in neuronal death following global cerebral ischemia can readily be studied in genetically modified mice provided a reliable model of ischemia is available. For that purpose, we developed a mouse model of global cerebral ischemia that induces consistent damage to different regions of...

journal_title：Brain research

authors： Olsson T,Wieloch T,Smith ML

更新日期：2003-08-29 00:00:00

abstract：:We examined the distribution of choline acetyltransferase (ChAT) mRNA in the brain of six autopsied individuals by in situ hybridization with 35S-labeled human ChAT riboprobes. Neurons containing hybridization signal for ChAT mRNA were observed in the nucleus of the diagonal band of Broca, the basal nucleus of Meynert...

journal_title：Brain research

authors： Kasashima S,Muroishi Y,Futakuchi H,Nakanishi I,Oda Y

更新日期：1998-09-21 00:00:00

abstract：:To test the hypothesis that stimulation of glial peroxidase activity by estrogens may play a role in the pathogenesis of the previously reported degenerative changes in the hypothalamic arcuate nucleus that occur in female rats treated with a long-acting estrogen preparation, the cellular localization and number of pe...

journal_title：Brain research

authors： Schipper HM,Lechan RM,Reichlin S

更新日期：1990-01-22 00:00:00

abstract：:Sokoloff's [14C]2-deoxyglucose method has been applied to investigate circadian variations in local cerebral glucose utilization (LCGU). Freely moving rats were tested during two phases of the circadian light/dark cycle. In the rats tested during darkness, elevations in LCGU, when compared with animals tested during t...

journal_title：Brain research

authors： Room P,Tielemans AJ

更新日期：1989-12-29 00:00:00

abstract：:The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes. Experimental results (resection of the olfactory tracts or unilateral kainic acid administration in the telencephalon) suggest that: the projection from the ...

journal_title：Brain research

authors： Bissoli R,Contestabile A,Marotta L,Poli A,Migani P

更新日期：1985-10-07 00:00:00

abstract：:The response of trunk neural crest cells taken from precise levels of the neural axis and cultured together with adjacent somites to Brain-derived neurotrophic factor (BDNF), was examined in cultures grown in a chemically defined medium. In control cultures, the number of neural crest-derived neurons expressing the HN...

journal_title：Brain research

authors： Kalcheim C,Gendreau M

更新日期：1988-06-01 00:00:00

abstract：:The distribution of pituitary adenylate cyclase-activating polypeptide (PACAP) was examined in the tooth pulp. In rat and human tooth pulps, PACAP-immunoreactive (IR) nerve fibers were observed around blood vessels and in the subodontoblastic and odontoblastic layers. The predentine and dentine were devoid of such ner...

journal_title：Brain research

authors： Ichikawa H,Sugimoto T

更新日期：2003-08-08 00:00:00

abstract：:Field potentials and radial current source-densities (CSDs) evoked by optic tract stimulation were observed in goldfish tectum in vitro. The effects of different concentrations of calcium and magnesium were studied to improve understanding of component events in retinotectal transmission and interpretations of effects...

journal_title：Brain research

authors： Langdon RB,Manis PB,Freeman JA

更新日期：1988-02-16 00:00:00