Abstract：
:The neuronal mechanisms of sneezing were examined in precollicular-postmammillary decerebrate cats. Mechanical stimulation (frequency 20 Hz, peak-to-peak displacement 0.5 mm) of the nasal membrane evoked a series of sneezes. In the same preparation, electrical stimulation (duration 0.2 ms, frequency 10 Hz, 5-50 microA) delivered to the lower brainstem also evoked sneezes. The changes in EMG activity and subglottic pressure during brainstem-induced sneeze were similar to those recorded nasal-induced sneeze. The sneeze-evoking region was located along the ventromedial part of the spinal trigeminal nucleus and the adjacent pontine-medullary lateral reticular formation, and extended rostrocaudally from P4.0 to P14.5 according to the Horsley-Clarke coordinates. These results suggest that the sneeze-evoking region is a distinct structure of the brainstem, having a homogeneous function. This region appears to control the epipharyngeal, intrinsic laryngeal and respiratory muscles. The integrated activity of these muscles underlies the generation of a sneeze.
journal_name
Brain Resjournal_title
Brain researchauthors
Nonaka S,Unno T,Ohta Y,Mori Sdoi
10.1016/0006-8993(90)90171-7subject
Has Abstractpub_date
1990-03-19 00:00:00pages
265-70issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(90)90171-7journal_volume
511pub_type
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