Abstract:
:Long-term potentiation (LTP) has received considerable attention as a neurophysiological model for studying the biology of memory. The present experiments examined the susceptibility of LTP in the dentate gyrus to modification by peripheral injections of amphetamine and epinephrine. Both drugs enhanced the development of LTP in a dose-related manner comparable to that seen previously in behavioral studies. Such results suggest that the development of this long-lasting electrophysiological change can be regulated by peripheral catecholamine levels in a manner analogous to that seen in behavioral studies of memory.
journal_name
Brain Resjournal_title
Brain researchauthors
Gold PE,Delanoy RL,Merrin Jdoi
10.1016/0006-8993(84)91124-7subject
Has Abstractpub_date
1984-07-02 00:00:00pages
103-7issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(84)91124-7journal_volume
305pub_type
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