Distribution of osmosensitive cells in the preoptic and adjacent regions of cat brains.

abstract：:Geranylgeranylacetone (GGA), more commonly known as an antiulcer agent, reportedly induces the heat shock protein 70 (HSP70) family in the gastric mucosa, liver and heart of rats. However, it has not been reported whether HSPs, and other factors that contribute to neuroprotection, are inducible in the brain following ...

journal_title：Brain research

authors： Fujiki M,Kobayashi H,Abe T,Ishii K

更新日期：2003-11-21 00:00:00

abstract：:The distribution of alpha scorpion toxin (alpha-ScTx) receptors was examined in differentiated mouse neuroblastoma cell cultures (N IE 115 clone) by electron microscope autoradiography using [125I]alpha-ScTx. This neurotoxin binds specifically to voltage-sensitive sodium channels, slowing down the inactivation of the ...

journal_title：Brain research

authors： Cau P,Massacrier A,Boudier JL,Couraud F

更新日期：1985-05-13 00:00:00

abstract：:Abnormally hyperphosphorylated tau is the major protein component of neurofibrillary tangles, the characteristic lesion of Alzheimer's disease (AD). Protein phosphatases (PP) type 1 (PP-1), type 2A (PP-2A) and type 2B (PP-2B) appear to be involved in the regulation of tau phosphorylation. The incidence of neurofibrill...

journal_title：Brain research

authors： Gong CX,Shaikh S,Grundke-Iqbal I,Iqbal K

更新日期：1996-11-25 00:00:00

abstract：:Evidence exists that repeated injections of melatonin in rather large doses inhibit sexual performance in male rats. In contrast, systemic injection of small doses of this hormone stimulates sexual activity of normal male rats. In these experiments, systemic acute administration of melatonin in small doses (10-100 mic...

journal_title：Brain research

authors： Drago F,Busa' L

更新日期：2000-09-29 00:00:00

abstract：:Earlier studies showed that pretreatment (3 and 6 h) of rats with the glucocorticoid hormone, dexamethasone, potentiated the drinking response to either central or peripheral administration of angiotensin II (AII). In the present study the specificity and mechanisms of this potentiation were examined. Intraperitoneal ...

journal_title：Brain research

authors： Sumners C,Gault TR,Fregly MJ

更新日期：1991-06-28 00:00:00

abstract：:Neurotensin is a putative peptide neurotransmitter in the mammalian brain. The light microscopic localization of the neurotensin receptor has been carried out by the autoradiographic localization of [3H]neurotensin binding sites in slide-mounted tissue sections. Large variations in receptor distribution were found, ev...

journal_title：Brain research

authors： Young WS 3rd,Kuhar MJ

更新日期：1981-02-16 00:00:00

abstract：:The central myelin sheaths of the recessive autosomal mutant mouse, Shiverer, were investigated by electron microscopy with special reference to the pattern of myelin formation. The results obtained may be summarized as follows: (1) the major dense line of myelin lamellae generally failed to be formed, but the axons w...

journal_title：Brain research

authors： Inoue Y,Nakamura R,Mikoshiba K,Tsukada Y

更新日期：1981-08-24 00:00:00

abstract：:The effect of a dihydropyridine Ca2+ antagonist, cilnidipine, on voltage-dependent Ca2+ channels was studied in acutely dissociated rat CA1 pyramidal neurons using the nystatin-perforated patch recording configuration under voltage-clamp conditions. Cilnidipine had no effect on low-voltage-activated (LVA) Ca2+ channel...

journal_title：Brain research

authors： Murai Y,Uneyama H,Ishibashi H,Takahama K,Akaike N

更新日期：2000-01-31 00:00:00

abstract：:The Timm and selenium staining techniques, based on silver amplification of endogenous zinc, produce an electron-dense precipitate in boutons. The staining characteristics of the two methods were compared by examining two allocortical regions, prepiriform cortex and entorhinal cortex, in the brain of the European hedg...

journal_title：Brain research

authors： Schwerdtfeger WK,Danscher G,Geiger H

更新日期：1985-11-25 00:00:00

abstract：:Female B6C3F1 mice were rendered tolerant-dependent on morphine by a combination of injections and pellet implantation. Mice were injected with morphine sulfate (20 mg/kg, s.c.) twice a day on day 1. On day 2, they were implanted s.c. with a 75 mg morphine pellet for 3 days. On day 5, the pellets were either left inta...

journal_title：Brain research

authors： Bhargava HN,Thomas PT,Thorat S,House RV

更新日期：1994-04-11 00:00:00

abstract：:Glutamic acid decarboxylase (GAD)- and gamma-aminobutyric acid (GABA)-like immunoreactivity was examined in the retina of the 13-lined ground squirrel (Spermophilus tridecemlineatus). Labeling was observed in the inner nuclear layer (INL), inner plexiform layer (IPL) and ganglion cell layer (GCL). The immunoreactive c...

journal_title：Brain research

authors： Lugo-García N,Blanco RE

更新日期：1991-11-08 00:00:00

abstract：:High (2.5-5 micrograms) doses of ventral tegmental morphine, which normally facilitate brain stimulation reward, were found to cause a complete cessation of bar pressing for brainstem stimulation in animals pretreated with systemic pimozide (0.175-0.35 mg/kg). It was hypothesized that the behavioral failure was due to...

journal_title：Brain research

authors： Rompré PP,Wise RA

更新日期：1989-01-16 00:00:00

abstract：:The disturbance of microcirculation following cerebral ischemia leads to an enlargement of cerebral infarct volume. Endogenous thrombin may play a role in this disturbance of microcirculation following cerebral ischemia. Therefore, the inhibition of thrombin may improve neurodegeneration and the accumulation of cerebr...

journal_title：Brain research

authors： Ohyama H,Hosomi N,Takahashi T,Mizushige K,Kohno M

更新日期：2001-06-01 00:00:00

abstract：:Maternal melatonin readily crosses the placenta to provide the fetus with time-of-day and day length information. To determine if melatonin could have a broader role during development than is currently recognized, melatonin receptor expression was examined in somatic sites during Siberian hamster embryogenesis. Using...

journal_title：Brain research

authors： Rivkees SA,Reppert SM

更新日期：1991-12-24 00:00:00

abstract：:Melanotropinergic neurons in the brain may mediate the known modulatory effects of alpha-melanocyte stimulating hormone (alpha-MSH) and adrenocorticotropic hormone (ACTH) on brain functions including thermoregulation, pituitary regulation, learning and behavior. To determine the distribution of brain melanotropin rece...

journal_title：Brain research

authors： Tatro JB

更新日期：1990-12-17 00:00:00

abstract：:Antisense oligodeoxynucleotides (ODNs) are used for the selective inhibition of gene expression. Antisense ODNs are promising tools for the investigation of physiological implications of proteins in the central nervous system of rodents in vivo. We have previously demonstrated that a phosphorothioate antisense ODN to ...

journal_title：Brain research

authors： Karle J,Witt MR,Nielsen M

更新日期：1997-08-08 00:00:00

abstract：:Invasion of scrapie agent into the central nervous system (CNS) was studied in rats following intracerebral and peripheral inoculation, the latter by injection into intact or transected sciatic nerve. Comparison of sleep-wakefulness alterations, neuropathological features, and time lag of electroencephalographic and c...

journal_title：Brain research

authors： Bassant MH,Baron H,Gumpel M,Cathala F,Court L

更新日期：1986-09-24 00:00:00

abstract：:Practical utilization of in vivo electrochemistry for brain studies has been impeded by difficulties with specificity and quantitative measurements. Studies in brain slices combined with similar data from intact animals have provided important new information on the nature of the electrochemical studies. Using the enz...

journal_title：Brain research

authors： Schenk JO,Miller E,Rice ME,Adams RN

更新日期：1983-10-24 00:00:00

abstract：:Social defeat is a powerful experience that often leads to drastic physiological and behavioral changes in many animal species. An example of such a change is conditioned defeat in Syrian hamsters. The neurophysiological mechanisms that underlie such changes are not yet fully understood, however, there is evidence tha...

journal_title：Brain research

authors： Jasnow AM,Huhman KL

更新日期：2001-11-30 00:00:00

abstract：:In the present studies we have examined the effects of a new calcium channel blocker, LY393615 ((N-Butyl-[5,5-bis-(4-fluorophenyl)tetrahydrofuran-2-yl]methylamine hydrochloride, NCC1048) in a model of hypoxia-hypoglycaemia in vitro and in a gerbil model of global and in two rat models of focal cerebral ischaemia in vi...

journal_title：Brain research

authors： O'Neill MJ,Hicks CA,Ward MA,Osborne DJ,Wishart G,Mathews KS,McLaughlin DP,Stamford JA,McCarty DR,Patrick KE,Roman C,Fleisch JH,Gilmore J,Boot JR

更新日期：2001-01-05 00:00:00

abstract：:The effects of acute ethanol exposure of chick spinal cord neurons were studied in tissue culture, using whole-cell voltage-clamp techniques. Results indicate that ethanol produces a persistent increase in the sensitivity of spinal neurons to GABA and glycine, with no change in input resistance or resting membrane pot...

journal_title：Brain research

authors： Celentano JJ,Gibbs TT,Farb DH

更新日期：1988-07-12 00:00:00

abstract：:Development and aging are often mirror image processes and this may be equally true in the effects of estradiol, a potent endogenous steroid regulating brain development as well as a therapeutic used to relieve the negative components of perimenopause. Both the developing and perimenopausal brain are characterized by ...

journal_title：Brain research

authors： McCarthy MM

更新日期：2011-03-16 00:00:00

abstract：:The putative neurotransmitter substance P was localized in the embryonic and neonatal mouse trigeminal nerve by indirect immunofluorescence. Central terminals in the nucleus caudalis gave a positive substance P-like immunofluorescence (SPLI) reaction of E13-E14. SPLI subsequently appeared in the peripheral mucous and ...

journal_title：Brain research

authors： Mohamed SS,Atkinson ME

更新日期：1982-07-01 00:00:00

abstract：:Mouse VD-hemopressin(α) (VD-Hpα) is an undecapeptide that selectively activates CB1 cannabinoid receptor in in vitro functional tests, and exerts CB1-mediated central antinociception in the mouse tail-flick assay. The aim of the present study was to further investigate the analgesic properties of supraspinal mouse VD-...

journal_title：Brain research

authors： Zheng T,Zhang R,Zhang T,Zhang MN,Xu B,Song JJ,Li N,Tang HH,Wang P,Wang R,Fang Q

更新日期：2018-02-01 00:00:00

abstract：:N2O antinociception was assessed in eight inbred and two outbred mouse strains. Results indicated the following order of responsiveness among the 10 strains: A/J (most sensitive), C57BL/6ByJ, C57BL/6J, BALB/cByJ, C3H/HeJ, Swiss-Webster, CXBK/ByJ, ICR, CBA/J and DBA/2J (least sensitive). These results demonstrate signi...

journal_title：Brain research

authors： Quock RM,Mueller JL,Vaughn LK

更新日期：1993-06-18 00:00:00

abstract：:Drugs thought to inhibit the actions of protein kinase C (PKC) and cAMP dependent protein kinase (A-kinase) were infused intrathecally into the subarachnoid space of the lumbar region of the spinal cord, and the effects on acoustic startle were measured. Previous work has shown that intrathecal infusion of drugs thoug...

journal_title：Brain research

authors： Boulis NM,Davis M

更新日期：1990-08-20 00:00:00

abstract：:Rats were trained on a radial maze and then given electrolytic lesions of the MS followed by a single intraseptal injection of 5 micrograms of NGF. Three days later they were re-tested on the maze. They were also post-operatively tested for hyperemotionality. MS lesions severely impaired performance on the radial maze...

journal_title：Brain research

authors： Janis LS,Glasier MM,Martin G,Stackman RW,Walsh TJ,Stein DG

更新日期：1995-05-08 00:00:00

abstract：:The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual ...

journal_title：Brain research

authors： Golub MS,Slotkin TA,Tarantal AF,Pinkerton KE

更新日期：2007-06-02 00:00:00

abstract：:Extracellular recordings were made from 29 respiration-phased neurons in the upper cervical spinal cord (C1-C3) in nine anesthetized rats while ipsilateral and contralateral vagi were stimulated via platinum hook electrodes. Neuronal responses to vagal stimulation were recorded using peristimulus histograms. An accumu...

journal_title：Brain research

authors： Dawkins MA,Foreman RD,Farber JP

更新日期：1992-10-30 00:00:00

abstract：:Weaver mutant mice alternated above chance levels but less often than normal mice in a 2-trial spontaneous alternation test. When the inter-trial (or retention) interval was manipulated, the weaver mutants alternated above chance levels only at the shortest (15 s) but not at the longest (4 or 5 min) intervals, contrar...

journal_title：Brain research

authors： Lalonde R

更新日期：1986-11-19 00:00:00