The ontogeny of substance P fibers in the mouse trigeminal nerve.

abstract：:Studies in regenerating goldfish optic nerves indicate that RNA may be axonally transported during optic nerve regeneration14,18,19. The present study was performed to determine if the axonal migration of RNA could be demonstrated during regeneration of the rat sciatic nerve. Rats, which had only the left sciatic nerv...

journal_title：Brain research

authors： Lindquist TD,Inogoglia NA

更新日期：1979-04-20 00:00:00

abstract：:Testosterone's (T) aggression-enhancing effects may be mediated in part by its 5alpha-reduced, 3-hydroxysteroid dehydrogenized metabolite 5alpha-androstane-3alpha,17beta-diol (3alpha-diol). To test this hypothesis, in Expt. 1 gonadectomized (gdx) C21 mice were administered T, 3alpha-diol, or vehicle and were observed ...

journal_title：Brain research

authors： Frye CA,Rhodes ME,Walf A,Harney JP

更新日期：2002-09-06 00:00:00

abstract：:The aim of this work was to study the role of the dorsal noradrenergic ascending pathway (DNAP), which originates in the locus coeruleus (LC) on the preovulatory surge of luteinizing hormone (LH) follicle-stimulating hormone (FSH) and prolactin (PRL) by producing bilateral electrolytic lesions (cathodal or anodal) in ...

journal_title：Brain research

authors： Anselmo-Franci JA,Franci CR,Krulich L,Antunes-Rodrigues J,McCann SM

更新日期：1997-09-05 00:00:00

abstract：:Endogenous gamma-aminobutyric acid (GABA) release from the rat medial preoptic area (MPOA) was measured in an in vitro slice technique with sensitive HPLC analysis. Oestrogen is demonstrated to increase GABA activity in the ovariectomised, oestrogen-primed (OVX-EB) rat prior to the luteinising hormone (LH) surge compa...

journal_title：Brain research

authors： Herbison AE,Heavens RP,Dyer RG

更新日期：1989-05-01 00:00:00

abstract：:Olfactory bulbectomy (OBX) transects the glutamatergic efferents from the olfactory bulbs, and the changes of glutamatergic N-methyl-D-aspartate (NMDA) receptor-mediated function are though to be involved in the behavioral deficits seen in OBX rats. In the present study, irritability scores in OBX male Wistar rats wer...

journal_title：Brain research

authors： Ho Y,Liu T,Tai M,Wen Z,Chow RS,Tsai Y,Wong C

更新日期：2001-05-11 00:00:00

abstract：:Solid pieces of the fetal septal region (SG) or hippocampus (HPC) were implanted in a cavity formed by aspiration of the fimbria fornix (FF) and the overlying cingulate cortex on one side in adult rats. In other lesioned animals cell suspensions obtained from the fetal septal area (SS) or the locus coeruleus region of...

journal_title：Brain research

authors： Buzsáki G,Gage FH,Czopf J,Björklund A

更新日期：1987-01-06 00:00:00

abstract：:Ionic currents induced by glutamate, kainate, quisqualate, and N-methyl-D-aspartate (NMDA) in cultured septal neurons were analyzed by fluctuations analysis. The power spectrum (PWS) of NMDA current fluctuations always fitted a single Lorentzian. PWSs of the other agonists fitted the sum of two Lorentzians; however, t...

journal_title：Brain research

authors： Shingai R,Ebina Y

更新日期：1988-05-10 00:00:00

abstract：:This study determined if vasopressin generates superoxide anion (O2(-)) in a cyclooxygenase dependent manner and if such production contributes to impairment of dilation to activators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid percussion brain injury (FPI) in newborn pig...

journal_title：Brain research

authors： Armstead WM

更新日期：2001-08-10 00:00:00

abstract：:Focal adhesion kinase (FAK) and proline-rich tyrosine kinase (PYK2) are two related non-receptor tyrosine kinases which are thought to play a role in transducing extracellular matrix (ECM)-derived survival signals into cells. The functions of FAK and PYK2 are linked to autophosphorylation of their specific tyrosine re...

journal_title：Brain research

authors： Ziemka-Nalecz M,Jaworska J,Sypecka J,Zalewska T

更新日期：2015-05-05 00:00:00

abstract：:The neurite promoting factors in the astroglial conditioned medium (As-CM) were characterized by using primary cultures of embryonic rat neocortical neurons. The factors in the As-CM bind to lectins such as wheat germ agglutinin (WGA), suggesting that they contain sugar moieties. When the WGA-bound fractions were appl...

journal_title：Brain research

authors： Mori T,Iijima N,Kitabatake K,Kohsaka S

更新日期：1990-09-10 00:00:00

abstract：:Chronic intermittent hypoxia (CIH) may cause sustained systemic hypertension by increasing sympathetic neural discharge (SND). We hypothesized that CIH alters brainstem circuits modulating SND. After 30 days of CIH exposure in rats, increased c-fos labeling was seen in the nucleus of the solitary tract and ventrolater...

journal_title：Brain research

authors： Greenberg HE,Sica AL,Scharf SM,Ruggiero DA

更新日期：1999-01-23 00:00:00

abstract：:Embryonic cortex from 19-day fetuses was transplanted in a medial frontal cortex wound cavity of 105-day-old male rats. Nissl-stained tissue revealed little internal laminar organization. Graft sections impregnated by the Loyez method exhibited bands of myelinated fibers surrounding implants as well as long-interconne...

journal_title：Brain research

authors： Mufson EJ,Labbe R,Stein DG

更新日期：1987-01-13 00:00:00

abstract：:Variation in cell loss and mossy fiber reorganization was examined along the longitudinal axis of the dentate gyrus from temporal lobe epileptic (TLE) patients. Previous evidence has indicated that the anterior hippocampus is prone to seizure activity. We compared granule and hilar cell number in addition to Timm stai...

journal_title：Brain research

authors： Masukawa LM,O'Connor WM,Lynott J,Burdette LJ,Uruno K,McGonigle P,O'Connor MJ

更新日期：1995-04-24 00:00:00

abstract：:We examined the responsiveness of rat vestibular ganglion neurons (VGNs) to exogenous neurotrophic factors, BDNF, NT-3, and GDNF, during postnatal development in dissociated cultures. VGNs were obtained from postnatal days (P) 1, 3, 7, and 14. After two days in culture, the survival of VGNs in control cultures without...

journal_title：Brain research

authors： Chihara Y,Iwasaki S,Kondo K,Yamasoba T

更新日期：2011-08-23 00:00:00

abstract：:The physiological role of amyloid precursor protein (APP), whose anomalous metabolite is a putative pathogen for Alzheimer disease, remains unclear. From the enhanced responsiveness to glutamate in cultured hippocampal neurons after the introduction of cDNA of APP695 (an isoform of APP dominant in human brain) using a...

journal_title：Brain research

authors： Tominaga-Yoshino K,Uetsuki T,Yoshikawa K,Ogura A

更新日期：2001-11-09 00:00:00

abstract：:The pretectal olivary nucleus of the squirrel monkey was examined in both normal and autoradiographic material. In the Nissl- and fiber-stained tissue the nucleus appears as a laminated structure. The distribution of retinal terminals within the nucleus was examined by the autoradiographic tracing method. These data r...

journal_title：Brain research

authors： Weber JT,Young R,Hutchins B

更新日期：1981-11-09 00:00:00

abstract：:The alpha7 nicotinic acetylcholine receptor (nAChR) plays an important role in cognitive processes and has generated recent interest as a potential drug target for treating neurodegenerative disorders such as Alzheimer's disease (AD). The property of Ca(2+) permeation associated with alpha7 nAChR agonism may lead to C...

journal_title：Brain research

authors： Bitner RS,Nikkel AL,Markosyan S,Otte S,Puttfarcken P,Gopalakrishnan M

更新日期：2009-04-10 00:00:00

abstract：:We have used the post-embedding immunogold labelling method using antibodies to gamma-aminobutyric acid (GABA) to obtain quantitative data on the distribution, frequency, postsynaptic targets and ultrastructural characteristics of GABA-immunoreactive (GABA-IR) boutons in the trigeminal motor nucleus of rats. We have a...

journal_title：Brain research

authors： Saha S,Appenteng K,Batten TF

更新日期：1991-10-04 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:Recent studies have shown that moving in synchrony with auditory stimuli boosts attention allocation and verbal learning. Furthermore rhythmic tones are processed more efficiently than temporally random tones ('timing effect'), and this effect is increased when participants actively synchronize their motor performance...

journal_title：Brain research

authors： Schmidt-Kassow M,Thöne K,Kaiser J

更新日期：2019-08-01 00:00:00

abstract：:The effects of morphine sulfate and two benzodiazepine derivatives, chlordiazepoxide HCl and diazepam, were evaluated upon single unit activity of the amygdaloid nuclear complex and hippocampal formation in immobilized cats. All surgical procedures were performed under halothane anesthesia and all wound margins were i...

journal_title：Brain research

authors： Chou DT,Wang SC

更新日期：1977-05-13 00:00:00

abstract：:Rd mutant mice are visually blind but they maintain the ability of synchronising their circadian rhythms to the external light-dark cycles. We used immunocytochemical procedures to detect light-induced Fos expression in the rd mice retina. We found that Fos is expressed in the rd retina in an unattenuated pattern thro...

journal_title：Brain research

authors： Huerta JJ,Llamosas MM,Cernuda-Cernuda R,García-Fernández JM

更新日期：1999-07-10 00:00:00

abstract：:A review of the available literature reveals that proliferation of ependyma occurs during embryological and early postnatal periods of development. Turnover, however, declines significantly during postnatal life and only low levels of residual activity persist into adulthood under normal conditions. In some regions of...

journal_title：Brain research

authors： Bruni JE,Del Bigio MR,Clattenburg RE

更新日期：1985-04-01 00:00:00

abstract：:There is no sex difference in the number of axodendritic synapses in the lateral septum of adult rats. However, the treatment of adult females with estradiol (E2) for 4 weeks increases significantly the number of synapses, whereas E2 treatment fails to increase the synaptic number in males, suggesting a possible sexua...

journal_title：Brain research

authors： Miyakawa M,Arai Y

更新日期：1987-12-08 00:00:00

abstract：:An in vitro model was used to study the cytokinetics of astroglial cells derived from neonatal rat cerebellum. Confluent monolayers of astrocytes (85% astroglial as assessed by GFAP immunoreactivity) were subcultured at low cell density and after 2-3 days growth were rendered quiescent by shifting them to low serum me...

journal_title：Brain research

authors： Kniss DA,Burry RW

更新日期：1988-01-26 00:00:00

abstract：:The effects of continuous clonidine infusion (10 micrograms/kg/h for 10 days) and the cessation of this infusion on the circadian body temperature rhythm of the spontaneously hypertensive (SH) rat were examined. This circadian rhythm was blunted significantly during the infusion of clonidine. The fall in body temperat...

journal_title：Brain research

authors： Lewis SJ,Maccarrone C,Jarrott B

更新日期：1986-10-22 00:00:00

abstract：:We have previously demonstrated that NMDA receptor-mediated extracellular adenosine accumulation in neuronal cultures is receptor-mediated and requires calcium influx. Because protein kinase C (PKC) is a calcium-dependent enzyme, we hypothesized that activation of PKC might be involved in NMDA-mediated adenosine accum...

journal_title：Brain research

authors： Lu Y,Rosenberg PA

更新日期：2007-06-25 00:00:00

abstract：:Secondary hemorrhage after thrombolysis in ischemic stroke is an important complication, which has been difficult to study in preclinical disease models. We have established and characterized a model of thromboembolic middle cerebral artery occlusion in rats. Advantages of this model include a very low rate of spontan...

journal_title：Brain research

authors： Sun L,Zhou W,Heiland S,Marti HH,Veltkamp R

更新日期：2011-01-12 00:00:00

abstract：:In the present study, receptor specific compounds were infused via a microdialysis probe in the vicinity of the right locus coeruleus (LC). During the infusion of these compounds, the extracellular content of noradrenaline was recorded in the ipsilateral medial prefrontal cortex (mPFC) with a second microdialysis prob...

journal_title：Brain research

authors： Kawahara Y,Kawahara H,Westerink BH

更新日期：1999-03-27 00:00:00

abstract：:The myelin vacuolation (mv) rat exhibits hypomyelination and vacuole formation in the myelin throughout the CNS, caused by a null mutation in the attractin gene. Myelin alterations in the spinal cord of mv rats progress during postnatal development and are more prominent in the white matter. In contrast, microglial ac...

journal_title：Brain research

authors： Izawa T,Yamate J,Franklin RJ,Kuwamura M

更新日期：2010-02-02 00:00:00