Synaptic plasticity to estrogen in the lateral septum of the adult male and female rats.

abstract：:The auditory cortical projections to the medial geniculate body (MGB) were studied in the cat. Lesions carefully restricted to each one of the subdivisions of the auditory and peri-auditory cortex were made and degenerating fibres were mapped in the MGB. In other experiments L-[4-5-3-H]leucine was injected into the co...

journal_title：Brain research

authors： Pontes C,Reis FF,Sousa-Pinto A

更新日期：1975-06-20 00:00:00

abstract：:We have previously demonstrated resiniferatoxin (RTX) to be an ultrapotent analog of capsaicin. Like capsaicin, RTX initially induces neurogenic inflammation, pain, and hypothermia and then causes desensitization of these responses. We examine here the duration of desensitization following acute treatment with the max...

journal_title：Brain research

authors： Szallasi A,Joo F,Blumberg PM

更新日期：1989-11-27 00:00:00

abstract：:Methamphetamine (METH) is one of the most commonly abused psychostimulant, and is known to induce dopaminergic neurotoxicity by generating oxidative stress and free radicals. In the present study we investigated the effects of METH on egr-1 and c-fos immediate early gene induction in different regions of mouse brain, ...

journal_title：Brain research

authors： Thiriet N,Zwiller J,Ali SF

更新日期：2001-11-16 00:00:00

abstract：:The active and passive membrane properties of developing Purkinje neurons in control cultures and cultures chronically treated with 20 or 40 mM ethanol for 1 or 2 weeks were examined using whole-cell current-clamp techniques. The membrane properties were characterized by the features of the voltage responses evoked by...

journal_title：Brain research

authors： Gruol DL

更新日期：1991-08-30 00:00:00

abstract：:Previous studies suggested the existence of two populations of cells in the mammalian sympathetic nervous system which differ in their ability to express phenylethanolamine N-methyltransferase (PNMT), the enzyme which specifically subserves the biosynthesis of epinephrine: (1) sympathoblasts and their progeny, the nor...

journal_title：Brain research

authors： Teitelman G,Skaper S,Baker H,Park DH,Joh TH,Adler R

更新日期：1984-04-01 00:00:00

abstract：:Double immunostaining for c-fos and oxytocin (OXY) was used to study the topography and time course of the metabolic activation of the hypothalamic oxytocinergic system upon osmotic stress in the male rat. Animals injected i.p. with hypertonic saline expressed c-fos-like immunoreactivity (FLI) in the paraventricular (...

journal_title：Brain research

authors： Giovannelli L,Shiromani PJ,Jirikowski GF,Bloom FE

更新日期：1992-08-14 00:00:00

abstract：:Sardinian alcohol non-preferring (sNP) rats, selected for their low ethanol preference and consumption, carry a point mutation (R100Q) in the gene coding for GABA(A) receptor alpha(6) subunit, which becomes more sensitive to diazepam-evoked GABA currents. We performed binding studies in the cerebellum of normal (RR) a...

journal_title：Brain research

authors： Sanna A,Congeddu E,Porcella A,Saba L,Pistis M,Peis M,Marchese G,Ruiu S,Lobina C,Grayson DR,Gessa GL,Pani L

更新日期：2003-03-28 00:00:00

abstract：:Electroconvulsive therapy (ECT) is widely used as a treatment for drug-resistant depression. The animal analogue of ECT is electroconvulsive shock (ECS) seizures. We have recently shown that repeated ECS seizures cause a long-lasting, perhaps permanent, enhancement in entorhinal-dentate evoked potentials in the rat. O...

journal_title：Brain research

authors： Gombos Z,Mendonça A,Racine RJ,Cottrell GA,Burnham WM

更新日期：1997-08-22 00:00:00

abstract：:Median preoptic nucleus (POMe) neurons are innervated by catecholaminergic and neuropeptide Y (NPY)-immunoreactive nerve terminals originating from the catecholamine area of the ventrolateral medulla (VLM). The possibility that such POMe neurons project to the VLM catecholamine area was investigated in the rat. Immuno...

journal_title：Brain research

authors： Kawano H,Masuko S

更新日期：1999-04-17 00:00:00

abstract：:The alpha-2 adrenergic agonist dexmedetomidine (Dex), 3-300 microg/kg, i.p., decreased cerebellar cGMP in a dose-dependent manner. Fentanyl (F), an opioid agonist, increased cerebellar cGMP at 0.3 mg/kg, s.c., and decreased it at doses >/=1 mg/kg. The inhibitory effect was receptor specific, that of Dex being blocked ...

journal_title：Brain research

authors： Vulliemoz Y,Virag L,Whittington RA

更新日期：1998-11-30 00:00:00

abstract：:We have previously observed that chronic cocaine administration increases levels of adenylyl cyclase and cAMP-dependent protein kinase (PKA) in the nucleus accumbens (NAc). In the present work we directly examined the involvement of the cAMP system at the level of the NAc in cocaine-induced locomotor activity and sens...

journal_title：Brain research

authors： Miserendino MJ,Nestler EJ

更新日期：1995-03-20 00:00:00

abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...

journal_title：Brain research

authors： Nunn PB,Seelig M,Zagoren JC,Spencer PS

更新日期：1987-05-05 00:00:00

abstract：:Intracellular recordings were made from rabbit nodose ganglion cells in vitro. Morphine (up to 100 micro M), normorphine (up to 10 micro M) and D-Ala2, Leu5-enkephalin (DADLE) (up to 5 micro M) each had no detectable effect on the electrical properties of the cell membrane, except for local anesthetic-like actions at ...

journal_title：Brain research

authors： Shefner SA,North RA,Zukin RS

更新日期：1981-09-21 00:00:00

abstract：:Prolonged exposure of opioid receptors to agonists leads to their regulation by the classical process of clathrin-dependent internalization, followed by their intracellular degradation (down regulation). We have previously shown that the opioid agonist etorphine induced an additional process of down regulation of mu-o...

journal_title：Brain research

authors： Kaplan E,Binyaminy B,Gafni M,Keren O,Sarne Y

更新日期：2011-04-22 00:00:00

abstract：:Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the eve...

journal_title：Brain research

authors： Durukan Tolvanen A,Tatlisumak E,Pedrono E,Abo-Ramadan U,Tatlisumak T

更新日期：2017-05-15 00:00:00

abstract：:Biochemical analysis of the binding of [125I]Bolton-Hunter coupled substance P [( 125I]BH-SP) to slide-mounted sections of rat brain demonstrated that [125I]BH-SP labels a binding site with a structure-activity profile characteristic of a substance P receptor. Under optimized preincubation and incubation conditions, t...

journal_title：Brain research

authors： Rothman RB,Herkenham M,Pert CB,Liang T,Cascieri MA

更新日期：1984-08-20 00:00:00

abstract：:It is well established that autonomic control of digestive function is modulated by central autonomic neurotransmission. In this context it has been shown that digestive function can be modulated by exogenous neuropeptides microinjected into specific brain sides. Furthermore, there is considerable evidence suggesting ...

journal_title：Brain research

authors： Tebbe JJ,Pasat IR,Mönnikes H,Ritter M,Kobelt P,Schäfer MK

更新日期：2005-03-02 00:00:00

abstract：:The properties of the beta amino acid transport system were examined in cultivated rat brain astrocytes, using the specific probe, beta-alanine. The uptake of beta-alanine is thought to be glial specific. Beta-alanine was not actively transported and the intracellular accumulation was not altered by coincubation with ...

journal_title：Brain research

authors： Cummins CJ,Glover RA,Sellinger OZ

更新日期：1982-05-06 00:00:00

abstract：:Twelve weeks after focal ventrolateral cerebrocortical suction lesions (ca. 12 X 4 mm) were made in rats, concentrations of the monoamines norepinephrine (NE), dopamine (DA), and serotonin (5-HT) and their metabolites were measured in several cortical and subcortical brain regions using high performance liquid chromat...

journal_title：Brain research

authors： Finklestein S,Campbell A,Baldessarini RJ,Moya KL,Haber SN

更新日期：1985-10-07 00:00:00

abstract：:In the present immunohistochemical study the distribution of nitric oxide synthase (NOS) was studied in various autonomic ganglia and in related peripheral tissues of the rat. For comparison some other neuronal markers including acetylcholinesterase and tyrosine hydroxylase as well as several neuropeptides were analys...

journal_title：Brain research

authors： Ceccatelli S,Lundberg JM,Zhang X,Aman K,Hökfelt T

更新日期：1994-09-12 00:00:00

abstract：:The present investigations were designed to assess the effect of the serotoninergic system on luteinizing hormone (LH) and LH-releasing hormone (LH-RH) secretion in female rats aged 14 and 30 days. The administration of 5-hydroxytryptophan (5-HTP; 75 mg/kg i.p.) increased hypothalamic serotonin (5-HT) concentrations i...

journal_title：Brain research

authors： Arias P,Szwarcfarb B,de Rondina DC,Carbone S,Sverdlik R,Moguilevsky JA

更新日期：1990-07-16 00:00:00

abstract：:The purpose of this study was to determine the effects of aging and gender on the volumes of total brain, brainstem, cerebellum and lateral ventricle of healthy Koreans by magnetic resonance imaging (MRI). Using three-dimensional MRI volumetry, we compared the volumes of various brain regions according to age and gend...

journal_title：Brain research

authors： Lee NJ,Park IS,Koh I,Jung TW,Rhyu IJ

更新日期：2009-06-18 00:00:00

abstract：:Recent studies have supported the existence of projections to the paraventricular and supraoptic nuclei of the hypothalamus that arise from non-catecholaminergic neurons in the nucleus of the solitary tract, whose terminal distribution is suggestive of interactions with both parvocellular and magnocellular neurosecret...

journal_title：Brain research

authors： Sawchenko PE,Pfeiffer SW

更新日期：1995-10-02 00:00:00

abstract：:Our recent results showed that angiotensin II or III (AII, AIII) microinjected into the zona incerta (ZI) significantly increased water intake. The most effective doses of AII and AIII were also defined. The two neuropeptides had their effects differently on drinking via different receptors. AII bound to AT(1) that wa...

journal_title：Brain research

authors： Bagi EE,Fekete E,Bányai D,Lénárd L

更新日期：2004-03-26 00:00:00

abstract：:Several studies, using electrical stimulation of parts of the hypothalamus, have shown, that different parts of the hypothalamus yield different behavioural responses upon stimulation. In order to differentiate between stimulation of neuronal cell bodies and passing fibres and to investigate the role of GABA in hypoth...

journal_title：Brain research

authors： Roeling TA,Kruk MR,Schuurmans R,Veening JG

更新日期：1993-06-25 00:00:00

abstract：OBJECTIVE:The modern brain imaging studies in patients with eating disorders have shown that neurotransmitting regulation differs distinctly from control groups. These disturbances have involved serotonin and dopamine system can be inherited and conditioned by genes. The aim of this work has been the analysis of associ...

journal_title：Brain research

authors： Mikołajczyk E,Grzywacz A,Samochowiec J

更新日期：2010-01-11 00:00:00

abstract：:We recently reported raphe neurones which frequently fired spikes in short bursts. However, the action potentials were broad and the neurones fired in a slow and regular pattern, suggesting they were an unusual type of 5-hydroxytryptamine (5-HT) neurone. In the present study, we investigated whether these putative bur...

journal_title：Brain research

authors： Hajós M,Sharp T

更新日期：1996-11-18 00:00:00

abstract：:There is evidence that heme oxygenase plays a role in cellular defense against reactive oxygen species and thereby has neuroprotective effects. We examined the interaction of Neotrofin, a cognitive-enhancing and neuroprotective drug, with the heme oxygenase system. In adult rats, both a single administration or seven ...

journal_title：Brain research

authors： Wang X,Hauptmann N,Taylor E,Foreman M,Khawli LA,Maines MD

更新日期：2003-02-07 00:00:00

abstract：:A highly specific antibody to alpha-melanocyte stimulating hormone (alpha-MSH) was used to histochemically localize and biochemically identify and quantitate alpha-MSH immunoreactivity in nerve fibers and cell bodies of the rat brain. alpha-MSH-like immunoreactivity was contained in fibers throughout the brain. The di...

journal_title：Brain research

authors： O'Donohue TL,Miller RL,Jacobowitz DM

更新日期：1979-10-26 00:00:00

abstract：:Norepinephrine (NE) and 3-methoxy-4-hydroxyphenylglycol (MOPEG) were determined in medio-basal hypothalamus of adult male rats using high-performance liquid chromatography to study nutritional modulation of noradrenergic turnover. Acute starvation, as well as 3 weeks of semistarvation with a low-protein high-carbohydr...

journal_title：Brain research

authors： Schweiger U,Warnhoff M,Pirke KM

更新日期：1985-06-03 00:00:00