TIA model is attainable in Wistar rats by intraluminal occlusion of the MCA for 10min or shorter.

abstract：:Nerve growth factor (NGF) and neurotrophin-3 (NT-3) are target-derived proteins that regulate innervating sympathetic neurons. Here, we used western blot analysis to investigate changes in NGF and NT-3 protein in several peripheral tissues following loss of sympathetic input. Following removal of the superior cervical...

journal_title：Brain research

authors： Randolph CL,Bierl MA,Isaacson LG

更新日期：2007-05-04 00:00:00

abstract：:In a focused attention task saccadic reaction time (SRT) to a visual target stimulus (LED) was measured with an auditory (white noise burst) or tactile (vibration applied to palm) nontarget presented in ipsi- or contralateral position to the target. Crossmodal facilitation of SRT was observed under all configurations ...

journal_title：Brain research

authors： Diederich A,Colonius H

更新日期：2008-11-25 00:00:00

abstract：:Stressors produce rapid activation of the hypothalamic-pituitary-adrenal axis, which typically resolves within 60-90 min following termination of the stressor. In addition, some stressors such as inescapable tailshock (IS) also produce elevated basal levels of corticosterone (CORT), and reduced serum levels of cortico...

journal_title：Brain research

authors： Deak T,Nguyen KT,Cotter CS,Fleshner M,Watkins LR,Maier SF,Spencer RL

更新日期：1999-11-20 00:00:00

abstract：:In the first postnatal month, the thickness of the cerebral cortex has different patterns of development in the male and female Long-Evans rat. All areas of the male cortex appear to develop at similar rates, very rapidly for the first 10 days, then more gradually reaching a peak somewhere between 30 and 40 days of ag...

journal_title：Brain research

authors： Diamond MC

更新日期：1987-05-01 00:00:00

abstract：:The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was studied in male hooded rats. Repeated kindling stimulations were delivered twice or three times daily until either 300 stimuli had been delivered or generalized convulsions had been observed to...

journal_title：Brain research

authors： Milgram NW,Michael M,Cammisuli S,Head E,Ferbinteanu J,Reid C,Murphy MP,Racine R

更新日期：1995-01-23 00:00:00

abstract：:The present study investigated the effect of dextromethorphan and 6,7-dinitroquinoxaline-2,3-dione (DNQX) pre-treatment on the development of cocaine- and lidocaine-induced seizures. The dopaminergic action of cocaine was also studied. The NMDA antagonist dextromethorphan and the non-NMDA (AMPA/kainate) antagonist DNQ...

journal_title：Brain research

authors： Barat SA,Abdel-Rahman MS

更新日期：1997-05-09 00:00:00

abstract：:We have previously reported the first successful production of monoclonal antibodies against the cholinergic neuronal marker, choline acetyltransferase (ChAT). We now report some inter-and intraspecies cross-reactivity studies of the monoclonal antibody AB1. This antibody reacted most strongly with bovine ChAT and wea...

journal_title：Brain research

authors： Levey AI,Wainer BH

更新日期：1982-02-25 00:00:00

abstract：:The effects of oligemia (moderate ischemia) on the brain need to be explored because of the potential role of subtle microvascular changes in vascular cognitive impairment and dementia. Chronic bilateral common carotid artery occlusion (BCCAO) in adult rats has been used to study effects of oligemia (hypoperfusion) us...

journal_title：Brain research

authors： Schmidt-Kastner R,Aguirre-Chen C,Saul I,Yick L,Hamasaki D,Busto R,Ginsberg MD

更新日期：2005-08-02 00:00:00

abstract：:Afferent pathways innervating the urinary bladder consist of myelinated Adelta- and unmyelinated C-fibers, the neuronal cell bodies of which correspond to medium and small-sized cell populations of dorsal root ganglion (DRG) neurons, respectively. Since hyperpolarization-activated cyclic nucleotide-gated cation (HCN) ...

journal_title：Brain research

authors： Matsuyoshi H,Masuda N,Chancellor MB,Erickson VL,Hirao Y,de Groat WC,Wanaka A,Yoshimura N

更新日期：2006-11-13 00:00:00

abstract：:We tested the hypothesis that a single systemic injection of 380 mg/kg of the muscarinic agonist pilocarpine would produce more diffuse and severe seizure-induced brain damage than a single injection of lithium (3 mEq/kg) followed 4 h later by < 1/10 the dosage of pilocarpine. The hypothesis was not supported; the pat...

journal_title：Brain research

authors： Bureau YR,Peredery O,Persinger MA

更新日期：1994-06-20 00:00:00

abstract：:Adhesion molecules on the endothelial surface of the blood-brain barrier (BBB) play an important role in the pathogenesis of many encephalopathies, including multiple sclerosis (MS) and cerebral malaria (CM). The expression of four surface molecules of relevance to MS and CM on the immortalized human umbilical vein en...

journal_title：Brain research

authors： Dobbie MS,Hurst RD,Klein NJ,Surtees RA

更新日期：1999-06-05 00:00:00

abstract：:When female golden hamsters are maintained on a photoperiod of less than 12.5 h of light per day, they go into a pineal gland-induced anestrus in 6-10 weeks. This acyclicity is similar in certain respects to the testicular regression which occurs in male golden hamsters maintained on a short photoperiod. A recent stud...

journal_title：Brain research

authors： Pieper DR,Samyn MM,Heverly RN

更新日期：1986-08-13 00:00:00

abstract：:Spectrally opponent processes of ON-type retinal ganglion cells and the blue preference behavior were identified by parallel physiological and behavioral experiments in Rana pipiens. Spectral opponency of retinal ON-units was measured by recording from optic nerve terminals in the anterior thalamus, while the retina w...

journal_title：Brain research

authors： Kicliter E,Kay CJ,Chino YM

更新日期：1981-04-06 00:00:00

abstract：:The effect of intrathecal (i.t.) galanin (GAL) on the prolonged increase of spinal reflex excitability produced by conditioning stimulation (CS) of unmyelinated muscle afferents was studied in decerebrate, spinalized, unanesthetized rats. A CS train (1 Hz, 20 s) applied to the unmyelinated fibers in the gastrocnemius ...

journal_title：Brain research

authors： Xu XJ,Wiesenfeld-Hallin Z,Hökfelt T

更新日期：1991-02-15 00:00:00

abstract：:We investigated the effects of inverting facial contour (hair and chin) and features (eyes, nose and mouth) on processing for static and dynamic face perception using magnetoencephalography (MEG). We used apparent motion, in which the first stimulus (S1) was replaced by a second stimulus (S2) with no interstimulus int...

journal_title：Brain research

authors： Miki K,Takeshima Y,Watanabe S,Honda Y,Kakigi R

更新日期：2011-04-06 00:00:00

abstract：:The cataleptic activity of morphine and methadone was markedly potentiated in frontally decorticated rats with no apparent changes in the onset or duration of action. Enhancement of the opioid cataleptic response was not due to changes in the availability of the drugs in the brain. The potentiation of methadone-induce...

journal_title：Brain research

authors： Consolo S,Forloni G,Ladinsky H,Palazzi E

更新日期：1988-05-24 00:00:00

abstract：:Based on the fact that several recent reports have indicated that non-immunosuppressive immunophilin ligands (IPLs) can activate neurite outgrowth or nerve regeneration, we investigated the neurotrophic factor-activating abilities of IPLs in vivo in order to clarify the molecular basis of neurotrophic-like activity. B...

journal_title：Brain research

authors： Tanaka K,Fujita N,Ogawa N

更新日期：2003-04-25 00:00:00

abstract：:The axons in the nerve fiber layer (NFL) of the adult rat retina were examined by transmission electron microscopy. NFL axons range in size from 0.12 to about 2.0 microm, with a peak at 0.3-0.4 microm. In addition to conventional small mitochondria in the NFL axons contain some large ones, which are similar to astrocy...

journal_title：Brain research

authors： Hildebrand C,Waxman SG

更新日期：1983-01-03 00:00:00

abstract：:The current study examined the effects of intracerebroventricular (icv) infused aminopeptidase-resistant analogs of angiotensin II (AngII) and angiotensin III (AngIII) on thirst and sodium appetite. The analogs, [D-Asp1D-Arg2]AngII and [D-Arg1]AngIII, were further protected from degradation by pretreatment with the am...

journal_title：Brain research

authors： Wilson WL,Roques BP,Llorens-Cortes C,Speth RC,Harding JW,Wright JW

更新日期：2005-10-26 00:00:00

abstract：:Several laboratories have documented an increase in hippocampal nerve growth factor (NGF) levels, measured with biological or immunological assays, within 1-2 weeks following septal lesions or fimbria/fornix transections. In the present study we have determined the increase in NGF-like biological activity in medium co...

journal_title：Brain research

authors： Collins F,Crutcher KA

更新日期：1989-06-26 00:00:00

abstract：:The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...

journal_title：Brain research

authors： Watanabe Y,Watanabe T,Kitagawa M,Taya Y,Nakayama K,Motoyama N

更新日期：1999-09-25 00:00:00

abstract：:The effect of maternal hyperthermia on the developmental state of newborn guinea pig brains has been studied. Mean litter size and mean body weights of young from control and experimental mothers did not differ. Mean brain weight of young from control mothers (2.72 +/- 0.02 g) was larger than that from experimental mo...

journal_title：Brain research

authors： Hutchinson R,Bowler K

更新日期：1984-06-01 00:00:00

abstract：:Due to the structural similarity to N-methyl-4-phenyl pyridinium (MPP(+)), paraquat might induce dopaminergic toxicity in the brain. However, its blood--brain barrier (BBB) penetration has not been well documented. We studied the manner of BBB penetration and neural cell uptake of paraquat using a brain microdialysis ...

journal_title：Brain research

authors： Shimizu K,Ohtaki K,Matsubara K,Aoyama K,Uezono T,Saito O,Suno M,Ogawa K,Hayase N,Kimura K,Shiono H

更新日期：2001-07-06 00:00:00

abstract：:We consider a random synaptic pruning in an initially highly interconnected network. It is proved that a random network can maintain a self-sustained activity level for some parameters. For such a set of parameters a pruning is constructed so that in the resulting network each neuron/node has almost equal numbers of i...

journal_title：Brain research

authors： Turova TS

更新日期：2012-01-24 00:00:00

abstract：:Immunohistochemical studies with an antiserum raised against tyrosine hydroxylase have allowed us to demonstrate a dense dopaminergic innervation of the globus pallidus in the squirrel monkey. This innervation derived mostly from two fascicles that detached themselves from the major ascending dopaminergic bundle arisi...

journal_title：Brain research

authors： Parent A,Smith Y

更新日期：1987-11-24 00:00:00

abstract：:Intracellular free calcium concentration ([Ca2+]i) was measured in cultured explants of myenteric plexus neurones by using the fluorescent calcium indicator Indol in combination with patch-clamp techniques. The basal [Ca2+]i was 94 nM and spontaneous oscillations in the internal free calcium concentration were recorde...

journal_title：Brain research

authors： Trouslard J,Mirsky R,Jessen KR,Burnstock G,Brown DA

更新日期：1993-10-08 00:00:00

abstract：:Intraperitoneal (i.p.) administration of sulfated CCK octapeptide (CCK-8S) has been shown to induce changes in neuronal activity in the nucleus of the solitary tract (NTS) and area postrema (AP), sensory parts of the dorsal vagal complex (DVC), and in the paraventricular nucleus of the hypothalamus (PVN), as determine...

journal_title：Brain research

authors： Mönnikes H,Lauer G,Arnold R

更新日期：1997-10-03 00:00:00

abstract：:It has been suggested that thiolic groups are essential for cytochrome c oxidase (COX) activity and other respiratory mitochondrial enzymes. Recent experiments showed that the thiolic antioxidant N-acetylcysteine (NAC) can protect against age-related impairment in COX activity in mice hepatic mitochondria. The present...

journal_title：Brain research

authors： Martínez Banaclocha M,Martínez N

更新日期：1999-09-18 00:00:00

abstract：:Experiments were conducted to (1) provide further evidence of the selectivity of [D-Ala2,Leu5,Cys6]enkephalin (DALCE) as an antagonist of delta (delta) receptor ligands and (2) use DALCE as a tool to explore the possible role of delta receptors in restraint stress. Dose- and time-response curves were generated for the...

journal_title：Brain research

authors： Calcagnetti DJ,Bowen WD,Holtzman SG

更新日期：1990-02-19 00:00:00

abstract：:The aim of this study is to verify whether anatomical changes occur in the brains of chess players. Besides, it is a potential attempt to evaluate diffusion properties along the tracts due to the diverse situations at anatomical level in different locations; moreover, conventional voxel-based analysis (VBA) has alread...

journal_title：Brain research

authors： Zhou S,Jin L,He J,Zeng Q,Wu Y,Cao Z,Feng Y

更新日期：2018-12-01 00:00:00