Abstract：
:Several laboratories have documented an increase in hippocampal nerve growth factor (NGF) levels, measured with biological or immunological assays, within 1-2 weeks following septal lesions or fimbria/fornix transections. In the present study we have determined the increase in NGF-like biological activity in medium conditioned by hippocampal slices at more prolonged times following medial septal lesion. In contrast to reports based on immunological assays, which demonstrate a transient increase in hippocampal NGF, elevated NGF-like biological activity was present in hippocampal slice-conditioned medium up to one year after a medial septal lesion.
journal_name
Brain Resjournal_title
Brain researchauthors
Collins F,Crutcher KAdoi
10.1016/0006-8993(89)90254-0subject
Has Abstractpub_date
1989-06-26 00:00:00pages
355-60issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(89)90254-0journal_volume
490pub_type
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