Intracellular calcium changes associated with cholinergic nicotinic receptor activation in cultured myenteric plexus neurones.

abstract：:We have previously demonstrated that ibotenate (IBO)-stimulated polyphosphoinositide (PPI) hydrolysis is increased for a long period in the amygdala/pyriform cortex (AM/PC) of amygdala (AM)- and hippocampal (HIPP)-kindled rats. This finding indicates that enhanced function of the PPI-coupled excitatory amino acid (EAA...

journal_title：Brain research

authors： Akiyama K,Daigen A,Yamada N,Itoh T,Kohira I,Ujike H,Otsuki S

更新日期：1992-01-08 00:00:00

abstract：:A major function of the dopamine in the striatum is to control the activity of its efferent systems which contain primarily GABAergic neurons. Direct intracerebral injections of haloperidol into the corpus striatum impaired the performance of rats trained to depress a lever in a sensitive reaction time task. Rats were...

journal_title：Brain research

authors： Amalric M,Koob GF

更新日期：1989-04-03 00:00:00

abstract：:Available studies indicate that the adrenergic stimulation of pineal cyclic GMP production involves stimulation of guanylyl cyclase activity by nitric oxide (NO) derived from arginine. This line of investigation was extended in the present study. Using a highly sensitive microassay, it was found that pineal NO synthas...

journal_title：Brain research

authors： Lin AM,Schaad NC,Schulz PE,Coon SL,Klein DC

更新日期：1994-07-18 00:00:00

abstract：:Awake, intact monkeys were trained to perform discrete flexion or extension movements of the hand about the wrist in response to visual signals. The object of the movement was to align a cursor, coupled to a manipulandum, on a target line. Cursor and target lines are displayed on a video monitor placed in front of the...

journal_title：Brain research

authors： Murphy JT,Kwan HC,MacKay WA,Wong YC

更新日期：1982-03-25 00:00:00

abstract：:Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This...

journal_title：Brain research

authors： Garnett S,Firnau G,Nahmias C,Chirakal R

更新日期：1983-11-28 00:00:00

abstract：:Region-specific noradrenergic inputs to the bed nuclei of the stria terminalis (BST) from the caudal medulla were studied using combined Fast Blue injections and tyrosine hydroxylase immunoreactivity (TH-ir). Injections into the rostral, dorsal, ventral and lateral BST resulted in predominantly ipsilateral retrograde ...

journal_title：Brain research

authors： Terenzi MG,Ingram CD

更新日期：1995-02-20 00:00:00

abstract：:3,4-Dihydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A metabolite of norepinephrine and epinephrine. DOPEGAL, but not other metabolites, kills differentiated PC-12 cells. However, the type of DOPEGAL induced cell death, whether necrosis or apoptosis, is not known. To determine the type of cell death tr...

journal_title：Brain research

authors： Burke WJ,Schmitt CA,Miller C,Li SW

更新日期：1997-06-20 00:00:00

abstract：:The transcription factor cAMP responsive element binding protein (CREB) is important in regulating immediate-early genes and some late-effector genes involved in neuroplasticity in response to peripheral injury and stressful insults. Partial nerve injury elicited neuropathic pain is accompanied by increased phosphoryl...

journal_title：Brain research

authors： Ma W,Hatzis C,Eisenach JC

更新日期：2003-10-24 00:00:00

abstract：:Techniques to induce activity-dependent neuronal plasticity in vivo allow the underlying signaling pathways to be studied in their biological context. Here, we demonstrate activity-induced plasticity at neuromuscular synapses of Drosophila double mutant for comatose (an NSF mutant) and Kum (a SERCA mutant), and presen...

journal_title：Brain research

authors： Freeman A,Bowers M,Mortimer AV,Timmerman C,Roux S,Ramaswami M,Sanyal S

更新日期：2010-04-22 00:00:00

abstract：:The presence and localization of synapsin I were investigated in the cat vestibular epithelium, using a rabbit anti-synapsin I antibody. The staining was performed by immunofluorescence or by a peroxidase-anti-peroxidase technique. A strong immunoreactivity was observed with both methods. It appeared as spherical patc...

journal_title：Brain research

authors： Favre D,Scarfone E,Di Gioia G,De Camilli P,Dememes D

更新日期：1986-10-08 00:00:00

abstract：:Cigarette smoke passed through the nasal cavity of atenolol pre-treated anesthetized spontaneously breathing rabbits caused a bradycardia which was significantly modified by intracisternal application of the 5-HT1A receptor ligands 8-OH-DPAT (50 micrograms.kg-1) and buspirone (200 micrograms.kg-1). 8-OH-DPAT attenuate...

journal_title：Brain research

authors： Futuro-Neto HA,Pires JG,Gilbey MP,Ramage AG

更新日期：1993-12-03 00:00:00

abstract：:Adolescence is a critical period for neurodevelopment. In the present study, we investigated the effects of peri-adolescent social isolation on latent inhibition (LI) and dopamine D2 receptor expression in the medial prefrontal cortex (mPFC) and nucleus accumbens (NAc) of young adult rats. Male Sprague-Dawley rats wer...

journal_title：Brain research

authors： Han X,Li N,Xue X,Shao F,Wang W

更新日期：2012-04-04 00:00:00

abstract：:The postnatal development of acetylcholinesterase (AChE, EC 3.1.1.7) and NADH-diaphorase was examined in the caudate-putamen nucleus and substantia nigra of rats ranging from 3 to 90 days in age. From 3 to 15 days post partum islands of AChE and NADH-diaphorase activity were observed in the caudate-putamen nucleus. In...

journal_title：Brain research

authors： Butcher LL,Hodge GK

更新日期：1976-04-23 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disease characterized by progressive loss of midbrain dopaminergic neurons. To gain an insight into the mechanisms underlying the progression of PD, gene expression analysis was performed using two different brain regions, the substantia nigra pars compacta (SN) a...

journal_title：Brain research

authors： Ohnuki T,Nakamura A,Okuyama S,Nakamura S

更新日期：2010-07-30 00:00:00

abstract：:Administration of either Tyr-D-Ala-Gly-MePhe-Gly(ol) (DAGO), a mu-opioid agonist, or nicotine into the VTA (A10) caused an increase in both dopamine (DA) and its metabolite levels in both the A10 region and DA nerve terminals in the nucleus accumbens of rats when assessed with dual probe brain dialysis. These findings...

journal_title：Brain research

authors： Yoshida M,Yokoo H,Tanaka T,Mizoguchi K,Emoto H,Ishii H,Tanaka M

更新日期：1993-10-08 00:00:00

abstract：:Male ICR mice were fed powdered laboratory chow containing phenobarbital for 7 days to induce tolerance. Mice were sacrificed and brains assayed for changes in GABA-mediated chloride flux into brain membrane vesicles (microsacs). Concentration-dependent stimulation of chloride flux by GABA alone was not affected by th...

journal_title：Brain research

authors： Allan AM,Zhang X,Baier LD

更新日期：1992-08-21 00:00:00

abstract：:Cytochemistry was used to examine the distribution of two pathways of utilization of hydrogen (Type I and Type II H) generated by glucose-6-phosphate dehydrogenase (G6PD) in circumventricular organs (CVOs) and the hypothalamo-neurohypophysial system in cryostat sections of rat brain. Type I H is defined as that portio...

journal_title：Brain research

authors： Summy-Long JY,Salisbury R,Marietta MP,Hartman RD,Weisz J

更新日期：1984-02-27 00:00:00

abstract：:After the microinjection of morphine (5 micrograms/0.5 microliter) into the periaqueductal gray resulted in an increase in the hot-plate and tail-flick response latency of the unanesthetized rat, the alpha-adrenergic antagonists yohimbine, rauwolscine and corynanthine were given intrathecally. This treatment resulted ...

journal_title：Brain research

authors： Camarata PJ,Yaksh TL

更新日期：1985-06-10 00:00:00

abstract：:In this study intracellular recording techniques were used to study the synaptic events related to phase-locking of cochlear nucleus cells to low frequency stimuli. A variable degree of phase-locking was noted even with units of the same low characteristic frequency. With low frequency phase-locking units an excitator...

journal_title：Brain research

authors： Britt RH

更新日期：1976-08-13 00:00:00

abstract：:This ERP study explores the brain's response to the manipulation of motor compatibility in action-related language. In Experiment 1 participants read sentences in which a protagonist performed two different manual actions either simultaneously or consecutively (e.g. While/after cleaning the wound he unrolled the banda...

journal_title：Brain research

authors： Santana EJ,de Vega M

更新日期：2013-08-14 00:00:00

abstract：:The effect of chronic ethanol administration on the density of basket cells in the dentate gyrus of mice selectively bred for their sensitivity to acute ethanol exposure (long-sleep, LS and short-sleep, SS) was assessed in two experiments. In addition, the effect of chronic ethanol on the density of dentate granule ce...

journal_title：Brain research

authors： Scheetz AJ,Markham JA,Fifková E

更新日期：1988-09-20 00:00:00

abstract：:Using a double-label immunofluorescence method, we analyzed the time course of the appearance of Fos and Jun in the nuclei of supraoptic nucleus (SON) neurons following intraperitoneal injection of hypertonic saline. Fos and Jun immunostaining appeared within 30 min, peaked at 90-120 min, and disappeared 4-5 h later. ...

journal_title：Brain research

authors： Wang K,Guldenaar SE,McCabe JT

更新日期：1997-01-23 00:00:00

abstract：:The neural manifestations of food avoidance learning in the mollusc, Pleurobranchaea, survive the surgical reduction of the preparation to the nearly isolated brain. These manifestations include increased synaptic inhibition and reduced synaptic excitation of the phasic paracerebral feeding command interneurons (PCps)...

journal_title：Brain research

authors： Kovac MP,Davis WJ,Matera EM,Morielli A,Croll RP

更新日期：1985-04-08 00:00:00

abstract：:Microinjection of the indirect GABAA antagonist, picrotoxin, or the mu opioid agonist, Tyr-D-Ala-Gly-NMe-Phe-Gly-ol (DAGO), into the ventral pallidum and substantia innominata (VP/SI) increases locomotor activity in rats. The VP/SI has direct and indirect projections to the region of the ventral mesencephalon containi...

journal_title：Brain research

authors： Austin MC,Kalivas PW

更新日期：1991-02-22 00:00:00

abstract：:Nitric oxide (NO) can have opposite effects on peripheral sensory neuron sensitivity depending on the concentration and source of NO, and the experimental setting. The aim of this study was to determine the role of endogenous NO production in the regulation of mechanosensitive Ca(2+) influx of dorsal root ganglion (DR...

journal_title：Brain research

authors： Chaban VV,McRoberts JA,Ennes HS,Mayer EA

更新日期：2001-06-08 00:00:00

abstract：:An in vitro preparation of the medulla oblongata of the rat was used to examine the responses to reducing pH, at constant CO2, of neurons in several identified nuclei. Neurons in an area close to the ventral surface, which is thought to be the location of pH-sensitive central respiratory chemoreceptors, did not respon...

journal_title：Brain research

authors： Miles R

更新日期：1983-07-25 00:00:00

abstract：:We studied the effects of transcranial magnetic stimulation (TMS) on muscle activation patterns and joint kinematics during oscillatory movements of a joint within a two-joint (elbow-wrist) synergy. Healthy young adults (N=8) performed cyclic movements in one of the joints while the other joint was or was not involved...

journal_title：Brain research

authors： Latash ML,Danion F,Bonnard M

更新日期：2003-01-31 00:00:00

abstract：:Estrogen has previously been shown to significantly change sympathetic and parasympathetic system output via an action within the central nuclei responsible for regulating autonomic tone. These estrogen-induced changes were observed within 30 min of systemic administration and could be blocked by the direct microinjec...

journal_title：Brain research

authors： Saleh TM,Connell BJ,McQuaid T,Cribb AE

更新日期：2003-11-14 00:00:00

abstract：:Neural correlates of conscious awareness can be comfortably studied when awareness of the target stimuli is a varying dependent variable in the experimental conditions where the key independent variables are kept invariant. We presented vernier targets backward masked by an invariant grating with invariant SOA. EEG da...

journal_title：Brain research

authors： Aru J,Bachmann T

更新日期：2009-05-19 00:00:00

abstract：:We examined the effect of gangliosides on Schwann cell cultures isolated from neonatal rat sciatic nerves. Addition of gangliosides (GM1, GM3, and ganglioside mixture) at concentrations between 0.25 and 2 mg/ml significantly diminished both the baseline rate of proliferation of the Schwann cells and their response to ...

journal_title：Brain research

authors： Sobue G,Taki T,Yasuda T,Mitsuma T

更新日期：1988-12-06 00:00:00