Responsiveness of rat vestibular ganglion neurons to exogenous neurotrophic factors during postnatal development in dissociated cultures.

abstract：:Several labeled neurotransmitter substances or precursors ( [3H]histamine, [3H]serotonin, and [3H]choline) were injected with pressure into the cell body of C2, an identified putative histaminergic neuron in the cerebral ganglion of Aplysia in order to study the selectivity of axonal transport. We examined transport o...

journal_title：Brain research

authors： Gotoh H,Schwartz JH

更新日期：1982-06-17 00:00:00

abstract：:Quantitative morphological changes in the superior colliculus (SC) and the parabigeminal nucleus (PB) were studied in hereditary bilaterally microphthalmic rat, which lacks the optic nerve completely. Volumes of the retinorecipient superficial collicular layers of SC (SCS) to the central gray matter were decreased by ...

journal_title：Brain research

authors： Tokunaga A,Sugita S,Otani K,Terasawa K

更新日期：1985-11-01 00:00:00

abstract：:Quantitative and qualitative data are reported for single cerebral hemispheric neurons in a 3-dimensional hydrated collagen lattice (HCL) culture system. Individual neurons not in contact with other cells or cell processes, including synapses, rapidly displayed two morphologically distinct classes of processes that co...

journal_title：Brain research

authors： Coates PW

更新日期：1986-02-01 00:00:00

abstract：:The molecular mechanisms regulating the retrograde axonal transport of nerve growth factor (NGF) are currently unknown. This study identifies some of the signalling events involved. The phosphoinositide 3-kinase (PI3-kinase) inhibitor wortmannin (1 nmol/eye) irreversibly inhibits the amount of 125I-betaNGF retrogradel...

journal_title：Brain research

authors： Reynolds AJ,Bartlett SE,Hendry IA

更新日期：1998-07-06 00:00:00

abstract：:Although norepinephrine-containing nerve terminals in the spinal cord synapse in the vicinity of sympathetic preganglionic cells, their effect on sympathetic outflow has remained unclear. Since survival during hypotension necessitates sustaining maximal sympathetic activity, we used experimental hypotension as a physi...

journal_title：Brain research

authors： Conlay LA,Maher TJ,Godley BF,Wurtman RJ

更新日期：1986-06-04 00:00:00

abstract：:Our previous studies have demonstrated that a mixture of bovine brain gangliosides ( BBG ) applied to Neuro-2a neuroblastoma cells markedly increased the degree and rate of neurite formation. In the present study, the cytoskeletal basis for BBG -mediated neurite outgrowth was investigated by comparing cells grown in t...

journal_title：Brain research

authors： Spero DA,Roisen FJ

更新日期：1984-03-01 00:00:00

abstract：:Retrograde axonal transport method of the fluorescent tracer FluoroGold (FG) was combined with immunocytochemistry to investigate the occurrence of nitric oxide synthase (NOS), somatostatin (SOM), neuropeptide Y (NPY) and vasoactive intestinal peptide (VIP) in both intrinsic and cortically projecting neurons of the ra...

journal_title：Brain research

authors： Kowiański P,Timmermans JP,Moryś J

更新日期：2001-06-29 00:00:00

abstract：:The regenerating optic nerve of goldfish first reestablishes a rough retinotopic map on the tectum, then goes through an activity dependent refinement that appears to involve the elimination of inappropriate branches from early regenerated arbors. Retinotopically appropriate branches and synapses may be stabilized bec...

journal_title：Brain research

authors： Schmidt JT,Shashoua VE

更新日期：1988-04-19 00:00:00

abstract：:Excitatory transmission along the perforant path from the entorhinal cortex to the granule cells of the dentate gyrus was evaluated two days after 10 min of transient cerebral ischemia in the rat. The amplitude of the population spike, and the amplitude and the initial slope of the population excitatory postsynaptic p...

journal_title：Brain research

authors： Chang HS,Steward O,Kassell NF

更新日期：1989-12-29 00:00:00

abstract：:Ethylcholine aziridinium ion (AF64A) diluted in artificial perilymph, or artificial perilymph alone was infused into the cochlea of chinchillas. After a survival time of 7 days, the cochleas were fixed with aldehydes, post-fixed in osmium and embedded in epoxy resin for light and electron microscopy. The ultrastructur...

journal_title：Brain research

authors： Morley BJ,Spangler KM,Schneider BL,Javel E

更新日期：1991-03-22 00:00:00

abstract：:Dissociated Muller (glial) cells from the neotenous tiger salamander retina respond electrogenically and rheogenically to three putative catecholamine (CA) neurotransmitters, epinephrine, norepinephrine and dopamine. All 3 CAs stimulate a net inward current and an increase in input resistance (Rn). The Muller cell res...

journal_title：Brain research

authors： Henshel DS,Miller RF

更新日期：1992-03-20 00:00:00

abstract：:The linear nucleus (Li) is a prominent cell group in the caudal hindbrain, which was first described in a study of cerebellar afferents in the rat by [Watson, C.R.R., Switzer, R.C. III, 1978. Trigeminal projections to cerebellar tactile areas in the rat origin mainly from N. interpolaris and N. principalis. Neurosci. ...

journal_title：Brain research

authors： Fu Y,Tvrdik P,Makki N,Palombi O,Machold R,Paxinos G,Watson C

更新日期：2009-05-19 00:00:00

abstract：:Changes in the astrocytic cytoskeleton were examined in amygdala kindled rats using immunocytochemical techniques. One week following kindling, there was a dramatic increase in immunoreactivity to glial fibrillary acidic protein and vimentin in astrocytes throughout amygdala, pyriform cortex and hippocampus bilaterall...

journal_title：Brain research

authors： Khurgel M,Racine RJ,Ivy GO

更新日期：1992-10-02 00:00:00

abstract：:The [14C]2-deoxyglucose (2-DG) technique has been widely utilized for quantitative measurement of local cerebral metabolic for glucose (1CMRG) in animals. The technique as presently used is limited by the energy of 14C beta-particles, which can travel relatively great distances in tissue. This results in limited audio...

journal_title：Brain research

authors： Alexander GM,Schwartzman RJ,Bell RD,Yu J,Renthal A

更新日期：1981-10-26 00:00:00

abstract：:Experiments were done in cats to identify neurons in the paramedian reticular nucleus (PRN) sending collateral axons to the region of the intermediolateral nucleus (IML) at different levels of the thoracic cord by using lectin-conjugated horseradish peroxidase (HRP) and double-labeling fluorochrome histochemistry to r...

journal_title：Brain research

authors： Elisevich K,Caverson MM,Flumerfelt BA,Hrycyshyn AW,Ciriello J

更新日期：1987-04-07 00:00:00

abstract：:C3H/HeJ mice are refractory to lipolysaccharide (LPS) in the periphery, primarily because their macrophages do not respond to LPS and produce pro-inflammatory cytokines such as interleukin-1 (IL-1). To determine if they are also refractory to LPS in the brain, behavior of C3H/HeJ mice was compared to LPS-sensitive C3H...

journal_title：Brain research

authors： Johnson RW,Gheusi G,Segreti S,Dantzer R,Kelley KW

更新日期：1997-03-28 00:00:00

abstract：:Multidrug efflux transporters of the ATP-Binding cassette (ABC) family, P-glycoprotein (Pgp), multidrug-resistance associated protein 4 (MRP4) and breast cancer resistance protein (BCRP), located on endothelial cells lining brain vasculature play important roles in limiting movement of substances into and enhancing th...

journal_title：Brain research

authors： Wijesuriya HC,Bullock JY,Faull RL,Hladky SB,Barrand MA

更新日期：2010-10-28 00:00:00

abstract：:A major effect of volatile anesthetics is to reduce excitatory synaptic transmission. In the present study the stimulated release of glutamate under the influence of increasing concentrations of isoflurane was studied in vitro by utilizing hippocampal slices from Wistar rats. Ca(2+)-dependent release was calculated by...

journal_title：Brain research

authors： Larsen M,Grøndahl TO,Haugstad TS,Langmoen IA

更新日期：1994-11-14 00:00:00

abstract：:4-Aminopyridine (4-AP), bicuculline and GABA were applied locally to dorsal horn cells in the lumbar spinal cord in Nembutal-anaesthetized cats and in spinal cats. 4-AP expanded the cutaneous receptive field of 29 of 33 cells tested. Bicuculline and GABA had little or no effect on receptive field size. ...

journal_title：Brain research

authors： Saadé N,Jabbur SJ,Wall PD

更新日期：1985-10-07 00:00:00

abstract：:Outbred rat lines such as Wistar rats are commonly used for models of depressive disorders. Such rats arise from random mating schedules. Hence, genetic drift occurs in outbred populations which could lead to genotypic and phenotypic heterogeneity between rats from different vendors. Additionally, vendor specific rear...

journal_title：Brain research

authors： Theilmann W,Kleimann A,Rhein M,Bleich S,Frieling H,Löscher W,Brandt C

更新日期：2016-07-01 00:00:00

abstract：:The immunolocalization of the 14-3-3 eta isoform in the anterior horn cells (AHCs) of patients with sporadic amyotrophic lateral sclerosis (ALS) and controls was examined. Compared with the immunolocalization of other 14-3-3 isoforms, the immunolocalization of the 14-3-3 eta isoform was either synaptic at the peripher...

journal_title：Brain research

authors： Umahara T,Uchihara T,Shibata N,Nakamura A,Hanyu H

更新日期：2016-09-01 00:00:00

abstract：:The binding of [3H]flunitrazepam and [3H]Ro5-4864 to crude homogenates of amygdala-kindled and 'yoked' control rat brains was evaluated in subjects sacrificed 60 days after the sixth generalized convulsion. Decreases in the Bmax for [3H]flunitrazepam binding to 'central-type' benzodiazepine receptors were observed in ...

journal_title：Brain research

authors： Burnham WM,Niznik HB,Okazaki MM,Kish SJ

更新日期：1983-11-21 00:00:00

abstract：:Swelling of glial and nerve cells is characteristic of brain damage in cerebral ischemia or trauma. The therapeutical efficiency of inhibition of Cl(-)-transport by a novel antagonist, the diuretic torasemide, on cytotoxic swelling of glial cells from lactacidosis, or glutamate was analyzed. Lactacidosis and the inter...

journal_title：Brain research

authors： Staub F,Peters J,Kempski O,Schneider GH,Schürer L,Baethmann A

更新日期：1993-04-30 00:00:00

abstract：:Neonatal rats were exposed to lead from parturition to weaning via the milk of dams drinking 0.2% lead acetate solution. The alterations of long-term potentiation (LTP) and paired-pulse facilitation (PPF) of hippocampal dentate gyrus in adult rats (90-115 days) following developmental lead exposure were studied in viv...

journal_title：Brain research

authors： Ruan DY,Chen JT,Zhao C,Xu YZ,Wang M,Zhao WF

更新日期：1998-09-28 00:00:00

abstract：:Tissue prisms prepared from neurosurgical samples of temporal neocortex of Alzheimer and control patients, upon depolarization preferentially released aspartate, glutamate and gamma-aminobutyrate (GABA). The Alzheimer and control samples did not significantly differ in the pattern of amino acid release, although acety...

journal_title：Brain research

authors： Smith CC,Bowen DM,Sims NR,Neary D,Davison AN

更新日期：1983-03-28 00:00:00

abstract：:Neurofibrillary tangles (NFT) are pathological cytoskeletal structures composed of paired helical filaments (PHF), and are found in neurons of patients afflicted with many neurodegenerative disorders, including Alzheimer's disease (AD). We previously found that an antiserum against casein kinase II (CK-II) stained NFT...

journal_title：Brain research

authors： Baum L,Masliah E,Iimoto DS,Hansen LA,Halliday WC,Saitoh T

更新日期：1992-02-21 00:00:00

abstract：:Horseradish peroxidase (HRP) in slow-release gel was unilaterally implanted in the transected dorsolateral funiculus (DLF) of either cervical, midthoracic, lumbar or sacral spinal cord levels of adult male rats. Cell mappings were made of all brain areas projecting through the DLF. Following cervical implants, dense l...

journal_title：Brain research

authors： Watkins LR,Griffin G,Leichnetz GR,Mayer DJ

更新日期：1981-11-02 00:00:00

abstract：:In 16-week-old Sprague-Dawley rats lightly anesthetized with pentobarbital, 5-HT (3-96 micrograms/kg, i.v.; n = 6) produced distinct pseudaffective responses and a dose-dependent (slope = 17.2 +/- 6.8 s/log10 dose) inhibition of the tail-flick (TF) reflex (ED50 = 32.6 +/- 9.2 micrograms/kg). In the same rats, a 1:1 co...

journal_title：Brain research

authors： Meller ST,Lewis SJ,Brody MJ,Gebhart GF

更新日期：1991-10-04 00:00:00

abstract：:We studied the effects of transcranial magnetic stimulation (TMS) on muscle activation patterns and joint kinematics during oscillatory movements of a joint within a two-joint (elbow-wrist) synergy. Healthy young adults (N=8) performed cyclic movements in one of the joints while the other joint was or was not involved...

journal_title：Brain research

authors： Latash ML,Danion F,Bonnard M

更新日期：2003-01-31 00:00:00

abstract：:Voltage-clamped GABA(A fast) and GABA(A slow) inhibitory postsynaptic currents (IPSCs) were selectively elicited in hippocampal area CA1 pyramidal neurons. Clinically relevant concentrations of halothane (1.2 vol.%) prolonged both GABA(A fast) and GABA(A slow) IPSC decay times approximately 2.5 fold, while having litt...

journal_title：Brain research

authors： Lukatch HS,MacIver MB

更新日期：1997-08-08 00:00:00