Abstract:
:The binding of [3H]flunitrazepam and [3H]Ro5-4864 to crude homogenates of amygdala-kindled and 'yoked' control rat brains was evaluated in subjects sacrificed 60 days after the sixth generalized convulsion. Decreases in the Bmax for [3H]flunitrazepam binding to 'central-type' benzodiazepine receptors were observed in the hypothalamus and ipsilateral cortex of kindled animals. The binding of [3H]Ro5-4864 to 'peripheral-type' benzodiazepine receptors was unchanged.
journal_name
Brain Resjournal_title
Brain researchauthors
Burnham WM,Niznik HB,Okazaki MM,Kish SJdoi
10.1016/0006-8993(83)90210-xsubject
Has Abstractpub_date
1983-11-21 00:00:00pages
359-62issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(83)90210-Xjournal_volume
279pub_type
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