Abstract：
:The binding of [3H]flunitrazepam and [3H]Ro5-4864 to crude homogenates of amygdala-kindled and 'yoked' control rat brains was evaluated in subjects sacrificed 60 days after the sixth generalized convulsion. Decreases in the Bmax for [3H]flunitrazepam binding to 'central-type' benzodiazepine receptors were observed in the hypothalamus and ipsilateral cortex of kindled animals. The binding of [3H]Ro5-4864 to 'peripheral-type' benzodiazepine receptors was unchanged.
journal_name
Brain Resjournal_title
Brain researchauthors
Burnham WM,Niznik HB,Okazaki MM,Kish SJdoi
10.1016/0006-8993(83)90210-xsubject
Has Abstractpub_date
1983-11-21 00:00:00pages
359-62issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(83)90210-Xjournal_volume
279pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Depolarization by K+ (50 mM) of cultured chick retina cells released 1.14 +/- 0.28% of the accumulated [3H] gamma-aminobutyric acid (GABA) in the absence of Ca2+, but when 1.0 mM Ca2+ was present, the internal free calcium ion concentration [Ca2+]i rose by about 750 nM and the [3H]GABA release about doubled to a value...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90974-e
更新日期：1992-09-18 00:00:00
abstract：:Hybridization histochemical and immunohistochemical methods were used to characterize the distribution of corticotropin-releasing factor (CRF) messenger RNA (mRNA) and peptide, respectively, in the central auditory system of the rat. Cell bodies expressing CRF mRNA and/or immunoreactivity (IR) were detected at each le...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90571-c
更新日期：1991-04-26 00:00:00
abstract：:The median preoptic nucleus (MnPN) of the hypothalamus contains sleep-active neurons including sleep-active GABAergic neurons and is involved in the regulation of nonREM/REM sleep. The hypocretinergic (HCRT) neurons of the perifornical-lateral hypothalamic area (PF-LHA) and serotonergic (5-HT) neurons of the dorsal ra...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.07.115
更新日期：2008-10-09 00:00:00
abstract：:To investigate whether a task rule carried over from the preceding trial modifies an early portion of the stimulus-locked lateralized readiness potential (sLRP), participants were asked to perform two different flanker tasks that were switched. One task required a left-hand response for a central letter "H" in a five-...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.05.050
更新日期：2010-07-30 00:00:00
abstract：:Preganglionic sympathetic neurons were labelled by retrograde transport of horseradish peroxidase, while catecholamine axon varicosities were marked by the uptake of 5-hydroxydopamine in the intermediolateral nucleus of the rat. The direct synaptic contacts from the catecholamine axons to the preganglionic sympathetic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90246-5
更新日期：1986-08-20 00:00:00
abstract：:The effect of central and peripheral administrations of angiotensin II (AII) on cerebrospinal fluid (CSF) formation was investigated in rabbits anesthetized with intravenous alpha-chloralose and urethane. CSF production was measured by the ventriculo-cisternal perfusion method with Blue dextran 2000 used as an indicat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91027-c
更新日期：1992-10-23 00:00:00
abstract：:A small, unilateral, penetrating wound was placed in the dorsolateral portion of the lumbosacral spinal cord in immature rats. Although this wound did not extend into the central canal area, some cells forming the walls of this canal underwent proliferative activity as demonstrated by [3H]thymidine autoradiography. Th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90783-0
更新日期：1980-11-10 00:00:00
abstract：:The preferential loss of GABAergic neurons in neocortex slab cultures after exposure to hypoxia was reinvestigated and confirmed using an improved morphometric analysis based on stereological principles. This preferential cell loss could be attenuated by treating the hypoxic slab cultures with the N-methyl-D-aspartate...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91031-7
更新日期：1989-10-30 00:00:00
abstract：:The involvement of the nucleus intercollicularis (ICo) region of the midbrain, an estrogen-sensitive area, in the expression of estrogen-dependent female courtship behavior was examined with radiofrequency lesion and intracranial hormone implant techniques. Bilateral lesions in the ICo region caused a reduction in the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90365-6
更新日期：1981-03-02 00:00:00
abstract：:Anticipation of an unavoidable painful stimulation, i.e. anticipation stress, induces analgesia. This analgesia may result from activation of the endogenous opioid peptide system as it is blocked by naloxone. The present paper characterizes the anticipation stress further by following the kinetics of the analgesia ris...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91674-0
更新日期：1989-12-04 00:00:00
abstract：:The effect of different dose, mode and duration of estradiol administration was examined in the different brain catecholaminergic areas in ovariectomized (OVX) female rats. We determined changes in mRNA levels of tyrosine hydroxylase (TH), rate-limiting enzyme in catecholamine (CA) biosynthesis of GTP cyclohydrolase I...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.04.002
更新日期：2004-07-23 00:00:00
abstract：:Regeneration of descending supraspinal projections were identified in adult goldfish following administration of HRP to different levels of the spinal cord. While in the untreated normal fish 17 nuclei were shown to project into the spinal cord, only 11 of them seem to have participated in the process of regeneration....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90159-k
更新日期：1993-08-27 00:00:00
abstract：:The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovarie...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90632-w
更新日期：1993-07-16 00:00:00
abstract：:The motor unit discharges in human hand muscles were recorded during voluntary isometric contraction. Bipolar wire electrodes were inserted in the right adductor pollicis muscle (AP) and first dorsal interosseous muscle (FDI) for the recordings. Motor unit activities from these muscles were investigated when subjects ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91461-7
更新日期：1986-04-30 00:00:00
abstract：:Dual-labeling immunohistochemical or in situ hybridization studies for the recently cloned epsilon-subunit and several neuropeptides were performed in the rat hypothalamus. We revealed an extensive co-expression (>90%) with hypocretin (Hcrt), oxytocin (OT), the gonadotropin-releasing hormone (GnRH), and the melanin-co...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)04270-1
更新日期：2003-03-28 00:00:00
abstract：:The effect of unilateral basilar papilla removal on glucose uptake in the 2nd and 3rd order auditory nuclei in the chick's brain stem, nucleus magnocellularis and nucleus laminaris, respectively, was examined with [3H]2-deoxy-D-glucose (2-DG) autoradiography. The tissue was processed according to a thaw-mount techniqu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90715-5
更新日期：1980-08-25 00:00:00
abstract：:The implantation of dopamine-rich mesencephalic grafts into the 6-hydroxydopamine (6-OHDA)-lesioned neostriatum of rats was accompanied by marked hyperinnervation by serotonin (5-HT) fibers. The purpose of this study was to examine the possibility that the graft-derived 5-HT hyperinnervation is governed by target-rela...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91667-4
更新日期：1992-10-02 00:00:00
abstract：:In previous studies we have tested the hypothesis that the termination of the period of sexual behavior in female guinea pigs results from the loss of progestin receptors from hypothalamic cell nuclei. We have shown that hormonal manipulations that delay heat termination also delay loss of hypothalamic nuclear progest...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90320-3
更新日期：1986-05-14 00:00:00
abstract：:The window method of radiolabeled protein analysis was used to study the transport kinetics of axonally transported cytomatrix proteins as they move through segments of mouse optic axons. Three slow component b (SCb) proteins--actin, a 30 kDa protein, and clathrin--were radiolabeled in the eye and were followed for up...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91019-d
更新日期：1990-05-28 00:00:00
abstract：:The aim of this study was to evaluate the effects of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in the developing brain. Thirty-seven newborn piglets were divided randomly into four groups: normothermic control (NC, n=9); hypothermic control (HC, n=7); normotherm...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)03186-9
更新日期：2001-12-20 00:00:00
abstract：:Mammalian transglutaminases (TGs) catalyze the irreversible post-translational modifications of proteins, the most prominent of which is the calcium-dependent formation of covalent acyl transfers between the γ-carboxamide group of glutamine and the ε-amino-group of lysine (GGEL-linkage). In the central nervous system,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.11.027
更新日期：2016-01-15 00:00:00
abstract：:Tetanic stimulation at 50 Hz elicited long-term potentiation (LTP) in the hippocampal CA1 region of 28-day-old control animals. In contrast, no significant potentiation was seen following the same tetanus in animals chronically exposed to 1000 ppm of lead acetate during development. Gender differences were observed in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02657-3
更新日期：2000-09-08 00:00:00
abstract：:Fos expression in vestibular brainstem and cerebellar regions was evaluated during vestibular adaptation in the Mongolian gerbil. In addition, vestibular adaptation was evaluated in both normal and compensated animals, as vestibular compensation reorganizes the vestibular pathway constraining adaptive processes. Behav...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.05.029
更新日期：2005-07-19 00:00:00
abstract：:Direct microinjection of cholinergic compounds into pontine reticular formation furnishes an excellent phenomenological model of the rapid eye movement phase of sleep (REM), but the mechanisms underlying this effect and whether they mimic the cellular events of natural REM remain unknown. Data presented here from intr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91549-7
更新日期：1989-01-02 00:00:00
abstract：:Considerable disagreement exists concerning the degree to which sparing and/or recovery of function occurs following CNS damage at birth rather than in adulthood. To study this question, the spinal cord was hemisected in neonatal and adult cats and the motor behavior of the two groups was compared when the neonatal op...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(83)90046-9
更新日期：1983-08-01 00:00:00
abstract：:In the present studies, we have evaluated the effects of N-[4-(2-¿[(3-Chlorophenyl)methyl]amino¿ethyl)phenyl]-2-thiophenecarbo ximidamide dihydrochloride (ARL 17477) on recombinant human neuronal NOS (nNOS) and endothelial NOS (eNOS). We then carried out pharmacokinetic studies and measured cortical nitric oxide synth...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02471-9
更新日期：2000-07-21 00:00:00
abstract：:The expression of adenylyl cyclase (AC) isoforms in the adult rat vestibular periphery was investigated using reverse transcription polymerase chain reaction (RT-PCR). AC II, IV and V mRNAs were expressed in both Scarpa's ganglion and vestibular end organs. In addition, in the vestibular end organs, an AC mRNA not pre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02007-2
更新日期：2000-03-24 00:00:00
abstract：:The autoradiographic [14C]2-deoxyglucose (2-DG) method was used to map ascending pathways which are influenced by arousing electrical stimulation of the midbrain reticular formation (RET) in alert rats. The major finding was that RET stimulation produces selective patterns of metabolic activation and suppression in di...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91190-4
更新日期：1985-09-30 00:00:00
abstract：:Effects of pre-treatment of synaptic membranes with beta-adrenoceptor agonists and cholera toxin on [3H]clonidine and [3H]yohimbine binding were examined in rat cerebral cortex. Pre-incubation of cerebral cortical membranes with isoproterenol (10 or 200 microM) or dobutamine (1, 10 or 200 microM) at 37 degrees C for 4...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90531-1
更新日期：1985-03-11 00:00:00
abstract：:Pretreatment with scopolamine, 3 mg/kg, prevented the acquisition of a passive avoidance task in rats. These amnesic effects of scopolamine could largely be overcome by treatment with 100 mg/kg of the nootropic drug piracetam. In order to identify the brain structures involved, the effects of these drugs on regional e...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91186-3
更新日期：1987-10-20 00:00:00
