Abstract:
:The Mesulam technique for horseradish peroxidase was used to study the subcortical afferent projections to a location in the hypothalamus that has been shown to control the complete cardiovascular (CV) response accompanying a specific emotional behavior. Major projections common to all baboons injected included the lateral septal nucleus; medial, cortical and basal amygdala; the anteroventral third ventricle area; the preoptic areas; the subiculum; the paraventricular nucleus of the thalamus; periventricular gray and the central gray of the midbrain; the midbrain tegmentum; locus ceruleus, parabrachial and raphe cells in the pons; and in the medulla, raphe nuclei, the nucleus of the solitary tract, in and around the dorsal motor nucleus of the vagus, and in the region of the nucleus ambiguus. Other projections in some but not all baboons included the subfornical organ and the midline and dorsomedial nuclei of the thalamus. The nucleus of the diagonal band of Broca was labeled to some degree with all injections but was most heavily labeled with the injection extending more laterally in the hypothalamus. These results fit well with physiological and behavioral studies dealing with neural control of emotional and CV responses and support the concept of an integrative area in the hypothalamus concerned specifically with the control of CV response accompanying emotion.
journal_name
Brain Resjournal_title
Brain researchauthors
Devito JL,Smith OAdoi
10.1016/0006-8993(82)90389-4subject
Has Abstractpub_date
1982-12-09 00:00:00pages
213-26issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(82)90389-4journal_volume
252pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The phenomenon whereby the relative timing between presynaptic and postsynaptic spiking determines the direction and extent of synaptic changes in a critical temporal window is known as spike timing-dependent synaptic plasticity (STDP). We have previously reported that STDP profiles can be classified into two types de...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.05.023
更新日期:2013-08-14 00:00:00
abstract::The expression of adenylyl cyclase (AC) isoforms in the adult rat vestibular periphery was investigated using reverse transcription polymerase chain reaction (RT-PCR). AC II, IV and V mRNAs were expressed in both Scarpa's ganglion and vestibular end organs. In addition, in the vestibular end organs, an AC mRNA not pre...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02007-2
更新日期:2000-03-24 00:00:00
abstract::The VIIIth cranial nerve projections in the hagfish, which has only one circular canal in the ear, were studied by transganglionic HRP transport. This nerve has two branches, the nervus utricularis (N. utr.) and the nervus saccularis (N. sac.), each with its own ganglion, the ganglion utriculare (G. utr.) and the gang...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91610-5
更新日期:1985-06-24 00:00:00
abstract::Brain capillaries form a selective interface, the blood-brain barrier (BBB), between the neural parenchyma and the blood. The factors which regulate this interface are poorly understood. Both the iris and retina possess vascular beds that express some BBB characteristics; therefore, they provide attractive models to f...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91323-k
更新日期:1993-12-03 00:00:00
abstract::The localization of [3H]corticosterone in the brain and pituitary of the adrenalectomized rat was studied by autoradiography. Corticosterone was concentrated preferentially by neurons in the hippocampus, septum, amygdala, and neocortex, with the hippocampal and septal neurons having the greatest concentration. [3H]-Co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(75)90937-3
更新日期:1975-01-10 00:00:00
abstract:PURPOSE:To determine whether antisense oligonucleotides (AODNs) targeted against CRX, a photoreceptor-specific trans-acting factor, suppress CRX expression and interphotoreceptor retinoid binding protein (IRBP) promoter activity. METHODS:Cultures of human retinoblastoma cells were transfected with chloramphenicol acet...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02884-0
更新日期:2001-10-19 00:00:00
abstract::1-(p-Bromobenzoyl)-piperazine-2,3-dicarboxylic acid (pBB-PzDA; 0.03-5 mM), an excitatory amino acid antagonist, was perfused through the guinea pig cochlea while monitoring various cochlear potentials. pBB-PzDA (1-5 mM) reversibly suppressed the amplitude of the compound action potential of the auditory nerve (CAP) an...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90934-7
更新日期:1989-05-15 00:00:00
abstract::Near-infrared spectroscopy (NIRS) enables noninvasive measurement of concentration changes of oxy- and deoxy-hemoglobin. The present study investigated cerebral representations of motion illusion by NIRS and examined several experimental procedures to determine an efficient procedure that can shorten the experimental ...
journal_title:Brain research
pub_type: 临床试验,杂志文章
doi:10.1016/j.brainres.2005.11.050
更新日期:2006-03-10 00:00:00
abstract::Mesencephalic dopamine neurons form synapses with acetylcholine (ACh)-containing interneurons in the nucleus accumbens (NAcc). Although their involvement in drug reward has not been systematically investigated, these large aspiny interneurons may serve an important integrative function. We previously found that repeat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.09.029
更新日期:2006-12-06 00:00:00
abstract::The central myelin sheaths of the recessive autosomal mutant mouse, Shiverer, were investigated by electron microscopy with special reference to the pattern of myelin formation. The results obtained may be summarized as follows: (1) the major dense line of myelin lamellae generally failed to be formed, but the axons w...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90269-9
更新日期:1981-08-24 00:00:00
abstract::The aim of this study is to verify whether anatomical changes occur in the brains of chess players. Besides, it is a potential attempt to evaluate diffusion properties along the tracts due to the diverse situations at anatomical level in different locations; moreover, conventional voxel-based analysis (VBA) has alread...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.07.003
更新日期:2018-12-01 00:00:00
abstract::(1) Spreading depression (SD) could be elicited in isolated carp retina by KCI application, the concomitants of which were similar to those described in other vertebrates. (2) The threshold for generating SD was greatly reduced by brief immersion of the retina in low ci-ringer's solutions. The properties of SD waves w...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90498-x
更新日期:1977-01-14 00:00:00
abstract::Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a reliable seed-based analysis of the resting-state brain activity to comprehensively delineate the subdivisions of striatal functional connectivity implicated in internet gaming disorder. Amon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.12.042
更新日期:2015-03-30 00:00:00
abstract::The regulatory role of endothelins in cerebral microvessels was investigated in a recently developed model system which allows the study of small cerebral vessels in their normal microenvironment. Using brain slices of the rat neocortex, it was shown that the isopeptide endothelin-3 (ET-3) had no effect on cerebral mi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(09)90024-5
更新日期:1994-09-26 00:00:00
abstract::The prefrontal cortex (PFC) plays a central role in preparatory and anticipatory attentional processes. To investigate whether subregions of the PFC play differential roles in these processes we investigated the effect of focal lesions to either lateral prefrontal (lateral PFC; n=11) or orbitofrontal cortex (OFC; n=13...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.06.017
更新日期:2013-08-21 00:00:00
abstract::A group of neurons in the caudal nucleus of the solitary tract (NTS) processes preproglucagon to glucagon-like peptide 1 (GLP-1), GLP-2 and oxyntomodulin. Whereas the anorectic capacity of all three neuropeptides has been demonstrated, only relatively little is known of preproglucagon mRNA regulation in the brain stem...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.10.026
更新日期:2008-01-02 00:00:00
abstract::Whereas the role of the hippocampus for spatial learning and long-term memory is largely undisputed, there is less evidence for a participation of hippocampal structures in spatial working memory operations. In an fMRI study (functional magnetic resonance imaging), we therefore examined the role of the hippocampus dur...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.07.065
更新日期:2010-10-01 00:00:00
abstract::Mounting evidence suggests that sleep loss negatively affects learning and memory processes through disruption of hippocampal function. In the present study, we examined whether sleep loss alters the generation, differentiation, and survival of new cells in the dentate gyrus. Rats were sleep restricted by keeping them...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.10.020
更新日期:2005-12-14 00:00:00
abstract::Tyrosine hydroxylase immunohistochemical analysis was performed on tissue sections through the pallidal complex from Nemistrina monkeys which had been made hemi-parkinsonian by intracarotid MPTP infusion 8-12 months earlier. The side contralateral to the MPTP infusion showed a dense dopaminergic innervation of the pal...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90318-p
更新日期:1991-08-16 00:00:00
abstract::The effect of serotonin agonists on the rhythmic excretion of the melatonin metabolite 6-sulphatoxymelatonin was examined in rats. The animals were maintained in 12L:12D and administered saline, quipazine (10 mg/kg), (+/-)-2-propylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide (8-OH-DPAT, 5 mg/kg) or buspi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00922-5
更新日期:1996-10-21 00:00:00
abstract::A qualitative immunohistochemical study was performed on calcineurin A- and calbindin-positive neurons in the spinal cord of transgenic mice, an animal model of amyotrophic lateral sclerosis, carrying the G93A mutation of the Cu/Zn-superoxide dismutase gene. The results show that calcineurin A-immunoreactive motoneuro...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)03048-1
更新日期:2001-01-19 00:00:00
abstract::The distribution of cells expressing mu-receptor mRNA and mu-receptor binding sites were compared in brain and spinal cord tissue sections using a combination of in situ hybridization and receptor autoradiographic techniques. mu-Receptor mRNA was visualized with a 35S-labeled cRNA probe directed to transmembrane III-V...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90031-0
更新日期:1994-04-18 00:00:00
abstract::The purpose of the present investigation was to record electrophysiological responses from single fibers in the hamster superior laryngeal nerve (SLN) that were responsive to chemical stimulation of the larynx. Twenty chemical solutions, commonly used in studies of mammalian gustatory physiology, were applied to taste...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91541-7
更新日期:1988-05-31 00:00:00
abstract::17β-estradiol (E2 or estrogen) is an endogenous steroid hormone that is well known to exert neuroprotection. Along these lines, one mechanism through which E2 protects the hippocampus from cerebral ischemia is by preventing the post-ischemic elevation of Dkk1, a neurodegenerative factor that serves as an antagonist of...
journal_title:Brain research
pub_type: 杂志文章,评审
doi:10.1016/j.brainres.2012.12.015
更新日期:2013-06-13 00:00:00
abstract::SC1 is an extracellular matrix glycoprotein that is related to the multifunctional protein SPARC. These matricellular members play regulatory roles in modulating cellular interactions. SC1 expression is enriched in the central nervous system during embryonic and postnatal development as well as in the adult brain. In ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)02270-9
更新日期:2002-03-29 00:00:00
abstract::The possibility that the motor cortex receives peripheral input directly from the thalamus was examined using the evoked potential method and the following results were obtained. Potentials in the motor cortex evoked by stimulation of superficial radial (SR) or group II deep radial (DR) nerve were neither abolished no...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90532-8
更新日期:1979-08-24 00:00:00
abstract::Although astrocytes express gamma-aminobutyric acid subtype-A (GABAA) receptors in the mature brain, GABAA receptor expression in a cultivation state remains controversial. In this study, we investigated the alteration of astrocytic GABAA receptor expression in in vitro and in vivo studies to elucidate the relevance o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.02.139
更新日期:2006-05-17 00:00:00
abstract::Gabapentin, a drug useful in several neurological and psychiatric disorders, decreased K(+) (15 mM)-induced [Ca(2+)](i) increase in Fura-PE3-loaded rat neocortical synaptosomes (IC(50)=9.7 microM; submaximal inhibition of 28.6%). This effect may indicate a selective modulation of presynaptic Ca(2+) influx in response ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02610-x
更新日期:2000-09-01 00:00:00
abstract::The occurrence of hypoxia-ischemia (HI) during early fetal or neonatal stages of an individual leads to the damaging of immature neurons resulting in behavioral and psychological dysfunctions, such as motor or learning disabilities, cerebral palsy, epilepsy or even death. No effective treatment is currently available ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)03094-9
更新日期:2002-09-27 00:00:00
abstract::The neurotoxin alpha-latrotoxin elicits spontaneous exocytosis of neurotransmitter from neurons and peptide hormones from endocrine cells. While the mechanism of action is not fully understood, both Ca(2+)-dependent and Ca(2+)-independent pathways participate in the facilitation of release, with the relative contribut...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.08.025
更新日期:2003-11-28 00:00:00