Abstract:
:The expression of adenylyl cyclase (AC) isoforms in the adult rat vestibular periphery was investigated using reverse transcription polymerase chain reaction (RT-PCR). AC II, IV and V mRNAs were expressed in both Scarpa's ganglion and vestibular end organs. In addition, in the vestibular end organs, an AC mRNA not previously reported in the rat was identified. The cloned sequence (GenBank accession no. AF184150) represented 95 amino acids with 100% similarity to the human AC VII and 94% to the bovine AC VII. AC VII mRNA also was found in the cerebellum but was undetectable in heart, kidney, liver and Scarpa's ganglion.
journal_name
Brain Resjournal_title
Brain researchauthors
Wackym PA,Troyanovskaya M,Popper Pdoi
10.1016/s0006-8993(00)02007-2subject
Has Abstractpub_date
2000-03-24 00:00:00pages
378-80issue
2eissn
0006-8993issn
1872-6240pii
S0006-8993(00)02007-2journal_volume
859pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Immunofluorescence on primary dissociated rat neuronal cultures (cortical, hippocampal, and cerebellar) and organotypic hippocampal cultures was used to investigate the pattern of distribution of cell-surface amyloid protein (APP). Antibodies directed against the extracellular (N-terminal) portion of APP or against th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00608-7
更新日期:1996-10-07 00:00:00
abstract::In urethane-anesthetized cats, ordinary and partial coherence values relating the 10-Hz rhythmic discharges of sympathetic nerves located on opposite sides of the body were not significantly affected by midsagittal section of the spinal cord from the seventh cervical through eighth thoracic or first cervical through e...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01355-l
更新日期:1995-01-30 00:00:00
abstract::Parvalbumin (PV) and calbindin (CB) immunoreactivities were assessed in nucleus robustus archistriatalis (RA) of male and female zebra finches, together with retrograde labelling of RA neurons. The results of double and triple labelling experiments suggested that, in males, moderately and faintly PV-positive neurons w...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02938-9
更新日期:2001-11-02 00:00:00
abstract::The effect of chronic ethanol administration on the fine structure of the hippocampal CA1 stratum oriens was examined in two lines of mice selectively bred for their differential sensitivity to acute ethanol exposure (long-sleep, LS and short-sleep, SS mice). Two experiments were performed. In the first experiment, mi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90718-9
更新日期:1987-04-21 00:00:00
abstract::Activating transcription factor 3 (ATF3) has been proposed as a marker for injured neurons. Thus, while undetectable normally in sensory, motor, or sympathetic neurons, ATF3-like immunoreactivity (ATF3-IR) is readily detectable in such cells after axotomy. Here we examined ATF3-IR in the superior cervical ganglion (SC...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.05.019
更新日期:2007-07-23 00:00:00
abstract::In response to in vitro stimulation with lipopolysaccharide (LPS), microglia induce the production of the inflammatory cytokine interleukin-1 beta (IL-1β) together with nitric oxide (NO) and superoxide anion (O2(-)). Here we investigated the role of NO and O2(-) in the signaling mechanism by which IL-1β is induced in ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.08.030
更新日期:2015-11-02 00:00:00
abstract::To gain insight into ATP-binding cassette transporter A1 (ABCA1) function and its potential role in AD pathology, we analyzed the expression of the cholesterol transporter ABCA1 in postmortem hippocampus from persons at different stages of dementia and AD associated neuropathology relative to cognitively intact normal...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.01.006
更新日期:2010-03-08 00:00:00
abstract::Granule cell progenitors in the dentate gyrus of the hippocampal formation have the unusual capacity to be able to divide in the brains of adult rats and primates. The basal proliferation rate of granule cell progenitors in the adult rat is low compared with development, however, it is possible that this rate may beco...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00030-4
更新日期:1998-04-20 00:00:00
abstract::Histaminergic fibers in the mesencephalic nucleus of the trigeminal nerve of Long-Evans rats were examined by light and electron microscopy after peroxidase-antiperoxidase immunocytochemical staining for histidine decarboxylase (HDC) as a marker. By light microscopy, neurons in the mesencephalic nucleus of the trigemi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90109-0
更新日期:1987-08-25 00:00:00
abstract:BACKGROUND INFORMATION:We recently proposed novel neurobiological ideas for discussion regarding the common nature (malfunction of a physicochemical phenomenon genetically programmed for the morphological execution of ontogenetic apoptosis), mechanism of formation (phase transition in an intraneuronal gel structure) an...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.02.011
更新日期:2007-05-25 00:00:00
abstract::Clinically, treatment options where fetal distress is anticipated or identified are limited. Allopregnanolone is an endogenous steroid, that positively modulates the GABA(A) receptor, and that has anti-apoptotic and anti-excitotoxic actions, reducing brain damage in adult animal models of brain injury. We sought to de...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.11.035
更新日期:2012-01-18 00:00:00
abstract::Ethylcholine aziridinium ion (AF64A) diluted in artificial perilymph, or artificial perilymph alone was infused into the cochlea of chinchillas. After a survival time of 7 days, the cochleas were fixed with aldehydes, post-fixed in osmium and embedded in epoxy resin for light and electron microscopy. The ultrastructur...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90889-4
更新日期:1991-03-22 00:00:00
abstract::Experiments were done in cats to identify neurons in the paramedian reticular nucleus (PRN) sending collateral axons to the region of the intermediolateral nucleus (IML) at different levels of the thoracic cord by using lectin-conjugated horseradish peroxidase (HRP) and double-labeling fluorochrome histochemistry to r...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90377-5
更新日期:1987-04-07 00:00:00
abstract::The primary objective of this study was to test the hypothesis that intravenous administration of autologous bone marrow cells could improve functional recovery after middle cerebral artery occlusion (MCAO) for 45 min in the rat and to determine specific time windows for efficacy. Mononuclear cells from autologous bon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.09.084
更新日期:2004-05-08 00:00:00
abstract::Infusion of carbachol into the lateral ventricles of rats at rates of 400 or 2000 ng/h for 6 h produced dose-related natriuresis, kaliuresis, and water drinking but no consumption of hypertonic NaCl solution. Electrolyte excretion and water intake were maximal during the first 2 h, and no further increases occurred af...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90593-1
更新日期:1985-04-22 00:00:00
abstract::The role of mu opioid receptors in the nucleus raphe dorsalis (DR) in the control of apomorphine-induced aggression was studied in rats. Administration in the DR of a selective mu opioid receptor agonist, (D-Ala2,N-Me-Phe4,Gly5-ol)-enkephalin (DAGO), in doses ranging from 0.01 to 1 microgram/0.5 microliter, dose-depen...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90706-3
更新日期:1989-05-29 00:00:00
abstract::Binding activities specific for each of [3H]prostaglandin (PG) D2, E2 and F2 alpha were detected in the P2 fraction of the human brain homogenates. The bindings were time-dependent, saturable and of high affinity; Kd values were 30 nM for all the PG bindings. Regional distribution of these binding activities was deter...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91358-7
更新日期:1985-09-02 00:00:00
abstract::An in vitro preparation was used to determine if rapidly transported radiolabeled protein which is isolated with the myelin fraction of frog sciatic nerves is similar to rapidly transported radiolabeled protein released from sciatic nerves. Sciatic nerves along with their eighth and ninth dorsal root ganglia were plac...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90525-x
更新日期:1982-05-13 00:00:00
abstract::Alterations in neurotrophic signaling pathways may contribute to the changes in the mesolimbic dopamine system induced by chronic morphine exposure. In a rat model of morphine dependence, we previously identified increased levels of phospholipase C gamma-1 (PLCgamma1) immunoreactivity specifically within the ventral t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.04.059
更新日期:2007-07-02 00:00:00
abstract::When a pair of stimuli separated by an appropriate interval is given to the right visceropleural connective of Aplysia californica the amplitude of the second EPSP elicited in cell R15 is usually smaller than the amplitude of the first EPSP. In the present paper we show that this phenomenon, synaptic depression, can b...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90379-6
更新日期:1976-06-04 00:00:00
abstract::This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.05.012
更新日期:2011-05-12 00:00:00
abstract::The possibility has been mentioned that a change in the structure is responsible for the deviant behavioral activity of gamma-endorphin in extracts of postmortem brain and pituitary gland samples of schizophrenic patients. This paper describes the investigation of this possibility by means of: amino acid composition a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90896-6
更新日期:1986-06-18 00:00:00
abstract::Zinc and other cations were iontophoretically applied to neurones in the frontoparietal cortex of urethane-anaesthetised rats and their effect on the activity of these cells was examined. Slow and often prolonged increases in firing rate occurred in 45.2% of neurones after zinc application and 72.7% after barium. Calc...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90097-0
更新日期:1984-10-08 00:00:00
abstract::Febrile seizure (FS) remains the most common childhood neurological emergency. Although many studies have been done, controversy exists as to whether these seizures are associated with a significant risk for cognitive impairment. The aim of our study is to check whether there is a spatial learning and memory deficit i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.02.026
更新日期:2014-04-04 00:00:00
abstract::A possible functional relationship between corticotropin-releasing factor (CRF) and opiate peptide neuronal systems (beta-endorphin, dynorphin1-17 and Met-enkephalin) and their interactions with gonadotropin releasing hormone (GnRH) in the mesencephalic central gray (MCG) for the regulation of lordosis behaviour was a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90414-7
更新日期:1985-06-10 00:00:00
abstract::The anteroventral subdivision of the medial amygdala (MeAV) is one of the vomeronasal structures involved in the control of hormonally dependent behaviors such as sexual and agonistic behaviors in rats. The present study investigates some anatomical and neurochemical parameters of this nucleus (volume, number of neuro...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.02.073
更新日期:2007-05-30 00:00:00
abstract::Averaged evoked potentials and unitary discharges in response to tooth pulp and acoustic click stimuli were recorded from the hippocampus of freely moving rats. The spatial distribution of evoked field responses to tooth pulp stimulation and acoustic clicks were identical. Averaged evoked potentials consisted of a lar...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90933-9
更新日期:1986-07-23 00:00:00
abstract::The purpose of this study was to ascertain whether visual acuity or contrast sensitivity function (CSF) is proportional to visual cortical function based on fMRI volume and level of activation or Z-score. Forced choice procedures were utilized to measure the monocular log minimal angle of resolution (logMAR) visual ac...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.10.082
更新日期:2011-01-07 00:00:00
abstract::Aggression is a major source of social stress with negative effects on health and well-being, yet limited information is known about the molecular mechanisms mediating aggressive behavior in swine. Ractopamine (RAC) is a β-adrenoreceptor agonist that enhances growth but increases aggressive behaviors in female pigs. T...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.11.035
更新日期:2011-03-24 00:00:00
abstract::In decerebrate dogs, stimulation of pelvic afferent fibres and distension of the rectum, vagina and urinary bladder brought about a sustained postural change and rhythmic abdominal compression. The posture, which resulted from flexion of the back and stifle joints, extension of the hip joints and lifting of the tail, ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90223-4
更新日期:1986-08-20 00:00:00