Adenylyl cyclase isoforms in the vestibular periphery of the rat.

Abstract:

:The expression of adenylyl cyclase (AC) isoforms in the adult rat vestibular periphery was investigated using reverse transcription polymerase chain reaction (RT-PCR). AC II, IV and V mRNAs were expressed in both Scarpa's ganglion and vestibular end organs. In addition, in the vestibular end organs, an AC mRNA not previously reported in the rat was identified. The cloned sequence (GenBank accession no. AF184150) represented 95 amino acids with 100% similarity to the human AC VII and 94% to the bovine AC VII. AC VII mRNA also was found in the cerebellum but was undetectable in heart, kidney, liver and Scarpa's ganglion.

journal_name

Brain Res

journal_title

Brain research

authors

Wackym PA,Troyanovskaya M,Popper P

doi

10.1016/s0006-8993(00)02007-2

subject

Has Abstract

pub_date

2000-03-24 00:00:00

pages

378-80

issue

2

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(00)02007-2

journal_volume

859

pub_type

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