Abstract：
:The anteroventral subdivision of the medial amygdala (MeAV) is one of the vomeronasal structures involved in the control of hormonally dependent behaviors such as sexual and agonistic behaviors in rats. The present study investigates some anatomical and neurochemical parameters of this nucleus (volume, number of neurons, number of glial elements, and of NADPH-diaphorase-positive neurons) in females in two estrous cycle phases (diestrous and estrous) and in males. We also investigate the possible existence of adult neurogenesis in this nucleus in the females. Results showed that volume and estimated number of Nissl-stained neurons in the MeAV vary with the estrous cycle phase: estrous females have greater values than diestrous females. As a consequence of these variations, there is a transient sex difference between males and diestrous females. Two subpopulations of NADPH-diaphorase-positive neurons were detected: intensely stained and medium stained. The intensely stained neurons were more numerous in the estrous than the diestrous females. Neither BrdU nor GFAP inmunostaining revealed significant differences between the two groups, suggesting that adult cell generation, i.e., increases in the number of glial elements, has no significant role in the changes detected in the number of Nissl-stained sections. In conclusion, the MeAV shows functional diergism, due to plastic changes in the female rat brain probably linked to the increase of estradiol during estrous. Finally, these changes are probably functionally related to changes in the behaviors that are controlled through this nucleus.
journal_name
Brain Resjournal_title
Brain researchauthors
Carrillo B,Pinos H,Guillamón A,Panzica G,Collado Pdoi
10.1016/j.brainres.2007.02.073subject
Has Abstractpub_date
2007-05-30 00:00:00pages
83-93eissn
0006-8993issn
1872-6240pii
S0006-8993(07)00489-1journal_volume
1150pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Slices of rat hippocampus were exposed to 700 MHz continuous wave radiofrequency (RF) fields (25.2-71.0 V m(-1), 5-15 min exposure) in a stripline waveguide. At low field intensities, the predominant effect on the electrically evoked field potential in CA1 was a potentiation of the amplitude of the population spike by...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02434-9
更新日期：2001-06-15 00:00:00
abstract：:In serum-free monolayer cultures of early postnatal weaver (wv/wv) cerebellum granule neurons show decreased attachment, survival and neurite outgrowth when compared to wild-type (+/+) littermate cultures. wv/wv Astrocytes display a more epithelioid morphology and altered proliferation. However, both morphology and pr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(86)90026-x
更新日期：1986-08-01 00:00:00
abstract：:The characteristics of [3H]sulpiride binding to the D2 dopamine receptor in rat striatal membranes were examined under several conditions. In the absence of sodium ions, the specific binding of [3H]sulpiride could not be detected. In the direct binding experiment, at 25 degrees C, the affinity of [3H]sulpiride for D2 ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90040-0
更新日期：1987-02-03 00:00:00
abstract：:The central nucleus of the amygdala (CEA) is selectively involved in the passive component of the behavioral (immobility) and the accompanying parasympathetic response during conditioned, stressful environmental challenges. Vasopressinergic mechanisms in the brain seem to play a role in these stress responses. The eff...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91529-n
更新日期：1992-11-20 00:00:00
abstract：:[1-14C]Octanoate (OCTO) is rapidly extracted from blood and metabolized by brain. Up to 6 min following an intravenous pulse injection the autoradiographic pattern of brain labeling reflects differences in blood flow and energy metabolism. When animals are given OCTO during visual or somatosensory stimulation the auto...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90486-x
更新日期：1985-06-03 00:00:00
abstract：:The activity of incertohypothalamic, tuberoinfundibular, mesolimbic and nigrostriatal dopamine (DA) neurons was estimated by measuring the rate of turnover of DA (decline of DA after alpha-methyltyrosine) in brain regions containing the cell bodies and terminals of these neurons. Estradiol benzoate (25 micrograms/kg/d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90267-1
更新日期：1984-12-03 00:00:00
abstract：:Voltage-activated Na+ channels in the primary sensory neurons are important for generation of action potentials and regulation of neurotransmitter release. The Na+ channels expressed in different types of dorsal root ganglion (DRG) neurons are not fully known. In this study, we determined the possible difference in te...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.09.051
更新日期：2004-12-17 00:00:00
abstract：:The precursor of the non-Abeta-component of Alzheimer's disease (AD) amyloid (NACP, alpha-synuclein) aggregates into insoluble filaments of Lewy bodies (LBs) in Parkinson's disease (PD) and dementia with LBs (DLB). The microtubule-associated protein tau is an integral component of filaments of neurofibrillary tangles ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01848-x
更新日期：1999-10-02 00:00:00
abstract：:The effects of adaptation/stimulus temperature (25 degrees C vs. 35 degrees C) on taste nerve responses to salt stimulation and amiloride suppression were assessed in rats. We measured the integrated responses of the chorda tympani nerve to 500 mM concentrations of NaCl, Na2SO4, sodium acetate (NaAc), KCl, K2SO4, pota...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/S0006-8993(96)01118-3
更新日期：1997-01-09 00:00:00
abstract：:A quantitative bioassay for nerve growth factor (NGF) has been previously described which employs PC13 rat pheochromocytoma cells. The basis of this assay is that rapid neurite regeneration by PC12 cells pretreated ('primed') with NGF for at least a week is quantitatively related to the amount of NGF present in the cu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)91218-0
更新日期：1983-03-14 00:00:00
abstract：:Cortistatin (CST) is a recently described neuropeptide with high structural homology with somatostatin. Its mRNA is restricted to gamma amino butyric acid (GABA)-containing cells in the cerebral cortex and hippocampus. CST modulates the electrophysiology of the hippocampus and cerebral cortex of rats; hence, it may be...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02336-7
更新日期：2000-03-06 00:00:00
abstract：:The hypoxia tracer fluorine-18 fluoromisonidazole ([18F]FMISO) and its tritiated counterpart ([(3)H]FMISO) have been used as markers of potentially salvageable brain (ischemic penumbra) after stroke. In experimental models, the dynamics and half-life of [3H]FMISO allow concurrent histology after 24 h. Our aim was to f...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.06.102
更新日期：2009-09-08 00:00:00
abstract：:Previous reports from our laboratory have demonstrated that ethanol- and cannabinoid-induced ataxia is modulated by cerebellar adenosine A(1) receptor because intracerebellar (i.c.b.) adenosine A(1) agonists potentiated and A(1) antagonist attenuated ataxia by these psychoactive drugs. In this study, the novel approac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03599-0
更新日期：2002-12-06 00:00:00
abstract：:Using a well-established model of binge-like ethanol treatment of rat pups on postnatal days (PD) 4-9, we found that maturation of GABAA receptor (GABAAR) miniature postsynaptic currents (mPSCs) was substantially blunted for medial septum/diagonal band (MS/DB) neurons in brain slices on PD 11-16. Ethanol reduced mPSC ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.04.054
更新日期：2013-07-03 00:00:00
abstract：:The neuroprotective effects of N-stearoyl-L-tyrosine (NSTyr) on cognitive function and neuronal plasticity during chronic cerebral hypoperfusion (CCH) in rats were investigated. After induction of CCH, NSTyr was administered daily for 3 months intraperitoneally. Cognitive functions were evaluated by Morris water maze ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.02.037
更新日期：2010-04-14 00:00:00
abstract：:Following injections of WGA-HRP into lower cervical segments, the distribution of anterograde labeled terminals of spinocerebellar fibers was examined in the vermal cortex of the cat. The labeled terminals were seen in sublobules Ib to VIc, VIIb, VIIIa and VIIIb, and lobule IX. They were present mainly in the medial p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91261-2
更新日期：1985-12-23 00:00:00
abstract：:BW 1003C87, 5-(2,3,5-trichlorophenyl)-2,4-diaminopyrimidine ethane sulphonic acid, has been tested for its in vitro and in vivo effects on glutamate release in rat brain tissue, and for its cerebro-protective action in two rodent models of cerebral ischemia. In rat brain slices the release of glutamate evoked by verat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91254-c
更新日期：1992-10-09 00:00:00
abstract：:Recently we reported that chronic treatment with 17beta-estradiol (E2) or tamoxifen (TAM) regulates the ovariectomy-induced downregulation of the key molecules linked to hippocampal synaptic plasticity and signal transduction pathway. We now report modulation of the antiapoptotic (Bcl-2) and proapoptotic (Bax) protein...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.01.080
更新日期：2008-04-14 00:00:00
abstract：:The effects of VIP and of peptides of the VIP family: secretin, glucagon, the porcine histidine isoleucine containing peptide (PHI) and the rat hypothalamic growth hormone-releasing hormone (rhGRF) on the cyclic AMP and inositol phosphate contents of isolated rat superior cervical ganglia were investigated. We demonst...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90200-3
更新日期：1986-06-25 00:00:00
abstract：:The influence of dopamine D1 receptor agonist, SKF 38393 has been studied in vitro in the model of low calcium spontaneous epileptiform discharges. Application of SKF 38393 (3 microM) to the perfusing medium evoked a decrease in neuronal firing rate of hippocampal CA1 neurons. The effect of SKF 38393 was blocked by pr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90208-s
更新日期：1990-09-24 00:00:00
abstract：:We investigated the responses of putative aortic baroreceptor neurons to mechanical stimulation of their processes. Putative aortic baroreceptor neurons were identified by applying the carbocyanine dye DiI to the adventitia of the aortic arch of anesthetized rats. After at least 1 week, the nodose ganglia were removed...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00153-4
更新日期：1997-05-16 00:00:00
abstract：:Opioid receptor subtype antagonists differentially alter food intake under deprivation (24 h), glucoprivic (2-deoxy-D-glucose, 500 mg/kg, i.p.) or palatable (10% sucrose) conditions with mu (beta-funaltrexamine) and kappa (nor-binaltorphamine), but not delta1 ([D-Ala2,Leu5,Cys6]enkephalin) opioid antagonists reducing ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00539-8
更新日期：1997-08-29 00:00:00
abstract：:The subfornical organ of the brain has a role in the regulation of fluid balance in higher animals. In this study the effects of salt loading and water deprivation on specific proteins in this organ were investigated. For 4 days, 3 groups of rats were given an appropriate fluid diet (control, 2% NaCl and water deprive...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91463-0
更新日期：1986-04-30 00:00:00
abstract：:Monoamine uptake inhibitors block the neurotoxic effects of methamphetamine (MA) upon dopaminergic and serotonergic neurons in the rat. The neurotoxic effects of MA upon dopaminergic neurons have previously been suggested to be mediated via formation of 6-hydroxydopamine (6-OHDA) from endogenous stores of dopamine (DA...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90889-j
更新日期：1990-05-14 00:00:00
abstract：:Focal cerebral ischemia elicits an inflammatory response characterized by the infiltration and accumulation of leukocytes, as well as the secretion of inflammatory mediators (Clark et al., Brain Res. Bull., 35 (1994) 387-392; Garcia et al., Am. J. Pathol., 144 (1994) 188-199; Wang et al., J. Neurochem. 71 (1998) 1194-...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02328-9
更新日期：2001-06-01 00:00:00
abstract：:Opioid modulation of ingestion includes general opioid antagonism of deprivation-induced water intake and intake of sucrose and saccharin solutions. Previous studies using selective subtype antagonists indicated that opioid effects upon deprivation-induced water intake occurred through the mu2 receptor and that opioid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91274-v
更新日期：1993-08-06 00:00:00
abstract：:Infusion of basic fibroblast growth factor (bFGF) prevents the loss of cholinergic neurons in the septum/diagonal band of broca following fimbria-fornix transection. However, an in vivo test of whether bFGF will also rescue injured non-cholinergic or cortical neurons has not been carried out. Previous studies have sho...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91707-l
更新日期：1992-09-25 00:00:00
abstract：:In the present studies, we have evaluated the effects of N-[4-(2-¿[(3-Chlorophenyl)methyl]amino¿ethyl)phenyl]-2-thiophenecarbo ximidamide dihydrochloride (ARL 17477) on recombinant human neuronal NOS (nNOS) and endothelial NOS (eNOS). We then carried out pharmacokinetic studies and measured cortical nitric oxide synth...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02471-9
更新日期：2000-07-21 00:00:00
abstract：:The present study attempts to elucidate the possible role of adenosine 3',5'-monophosphate (cAMP) and prostaglandin E2 (PGE2) in the function of the neural luteinizing hormone-releasing hormone (LH-RH) apparatus. To this end, in vitro LH-RH release from superfused hypothalamic fragments and cAMP production by hypothal...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90162-9
更新日期：1986-10-29 00:00:00
abstract：:(1) Visual, auditory and olfactory input were not necessary for the performance of the lordosis reflex by female rats. Since taste is not involved in this behavior, somatosensory input must be sufficient for triggering the lordosis reflex. (2) Surgical cutaneous denervation markedly reduced the frequency and strength ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90987-2
更新日期：1976-01-09 00:00:00
