Abstract：
:The subfornical organ of the brain has a role in the regulation of fluid balance in higher animals. In this study the effects of salt loading and water deprivation on specific proteins in this organ were investigated. For 4 days, 3 groups of rats were given an appropriate fluid diet (control, 2% NaCl and water deprived), with all groups having free access to food. Animals were killed by decapitation, and the subfornical organ was quickly dissected out and incubated for 6 h in a medium containing [35S]methionine and [35S]cysteine. Proteins from these organs were then separated by two-dimensional electrophoresis, and the resulting autofluorographs were analyzed by scanning densitometry. The results show that the incorporation of labeled amino acids into 8 proteins was changed due to the experimental manipulations.
journal_name
Brain Resjournal_title
Brain researchauthors
Santer DM,Heydorn WE,Creed GJ,Klein DC,Jacobowitz DMdoi
10.1016/0006-8993(86)91463-0subject
Has Abstractpub_date
1986-04-30 00:00:00pages
107-14issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(86)91463-0journal_volume
372pub_type
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