Calcium channel types mediating synaptic transmission during aging.

abstract：:In view of the inconclusive findings relating the nuclei of the mammillary bodies (MB) with spatial memory, we evaluated the oxidative metabolic activity of the medial and lateral nuclei of the mammillary bodies (MB) after training young rats (30 days) of both sexes in the Morris water maze. Different groups were trai...

journal_title：Brain research

authors： Conejo NM,González-Pardo H,Vallejo G,Arias JL

更新日期：2004-06-11 00:00:00

abstract：:Using a double-labelling procedure, morphological relationships existing between dopaminergic and indoleaminergic neuronal systems in the rat brain were investigated. First, thanks to a tryptamine (T) antiserum, we visualized this indoleamine in all mesencephalic regions and showed that the T-immunoreactivity (IR) see...

journal_title：Brain research

authors： Dabadie H,Mons N,Geffard M

更新日期：1990-03-26 00:00:00

abstract：:Microinjection of the neuronal inhibitor muscimol into the midbrain lateral/dorsolateral periaqueductal gray (l/dlPAG) suppresses increases in heart rate (HR) and mean arterial pressure (MAP) evoked by microinjection of the GABA(A) receptor antagonist bicuculline methiodide (BMI) into the dorsomedial hypothalamus (DMH...

journal_title：Brain research

authors： de Menezes RC,Zaretsky DV,Fontes MA,DiMicco JA

更新日期：2006-05-30 00:00:00

abstract：:DJ-1 was identified as an oncogene and also as a causative gene for a familial form of Parkinson disease (PD). DJ-1 plays various roles in anti-oxidative stress response. Superfluous oxidation of DJ-1 at cysteine residue 106 (C106), an inactive form of DJ-1, was observed in PD patients. DJ-1-binding compound B, which ...

journal_title：Brain research

authors： Niki T,Endo J,Takahashi-Niki K,Yasuda T,Okamoto A,Saito Y,Ariga H,Iguchi-Ariga SMM

更新日期：2020-02-15 00:00:00

abstract：:Electroconvulsive therapy (ECT) is widely used as a treatment for drug-resistant depression. The animal analogue of ECT is electroconvulsive shock (ECS) seizures. We have recently shown that repeated ECS seizures cause a long-lasting, perhaps permanent, enhancement in entorhinal-dentate evoked potentials in the rat. O...

journal_title：Brain research

authors： Gombos Z,Mendonça A,Racine RJ,Cottrell GA,Burnham WM

更新日期：1997-08-22 00:00:00

abstract：:Our recent study has shown that many afferent fibers in the ventral root are third branches of dorsal root ganglion cells in addition to their processes in the peripheral nerve and the dorsal root. From results of this study, we hypothesized that most of the afferent fibers in the normal ventral root are extra process...

journal_title：Brain research

authors： Oh UT,Kim KJ,Baik-Han EJ,Chung JM

更新日期：1989-10-30 00:00:00

abstract：:One optic nerve of mature goldfish was crushed in the orbit and allowed to regenerate. During regeneration impulse activity was eliminated by periodic intraocular injections of tetrodotoxin (TTX). At 32-104 days, the retinotopography of the retinotectal projection was measured autoradiographically by intraocular [3H]p...

journal_title：Brain research

authors： Meyer RL

更新日期：1983-02-01 00:00:00

abstract：:A simple pressure injection technique was developed to deliver substances into specific regions of the embryonic and neonatal mouse brain in vivo. The retrograde tracers Fluorogold and cholera toxin B subunit were used to test the validity of the technique. Injected animals survived the duration of transport (24-48 h)...

journal_title：Brain research

authors： Davidson S,Truong H,Nakagawa Y,Giesler GJ Jr

更新日期：2010-01-11 00:00:00

abstract：:Neonatal rats were exposed to lead from parturition to weaning via the milk of dams drinking 0.2% lead acetate solution. The alterations of long-term potentiation (LTP) and paired-pulse facilitation (PPF) of hippocampal dentate gyrus in adult rats (90-115 days) following developmental lead exposure were studied in viv...

journal_title：Brain research

authors： Ruan DY,Chen JT,Zhao C,Xu YZ,Wang M,Zhao WF

更新日期：1998-09-28 00:00:00

abstract：:Spontaneous hippocampal EEG activity and evoked field potentials were investigated in intact rats and in animals with fetal hippocampal grafts. Pieces of hippocampal grafts, derived from 15- to 16-day-old fetuses, were used to prepare cell suspensions and grafted directly into the intact hippocampus. Control animals r...

journal_title：Brain research

authors： Buzsáki G,Masliah E,Chen LS,Horváth Z,Terry R,Gage FH

更新日期：1991-07-19 00:00:00

abstract：:Hypothalamus and frontal cortex beta-adrenergic receptors, as measured by [125I]cyanopindolol binding, were investigated in male rats both after 4 days of acute starvation and after 2 weeks of semistarvation with dietary manipulation. Moreover, to test whether lymphocyte beta 2-adrenergic receptors can be used as a ma...

journal_title：Brain research

authors： Lonati-Galligani M

更新日期：1988-03-01 00:00:00

abstract：:This study investigated the relationship between central cholinergic neurons and insulin secretion in bilateral adrenalectomized fed rats. Neostigmine (a cholinesterase inhibitor, 5 x 10(-8) mol) administered into the third cerebral ventricle produced significant increases in hepatic venous plasma insulin and glucose ...

journal_title：Brain research

authors： Gotoh M,Iguchi A,Yatomi A,Uemura K,Miura H,Futenma A,Kato K,Sakamoto N

更新日期：1989-07-24 00:00:00

abstract：:Serum-free aggregating cell cultures of fetal rat telencephalon grown in the presence of 3 ng/ml (5 X 10(-10) M) epidermal growth factor (EGF) until day 12 showed 2- to 3-fold increased activities in the two glial enzymes, glutamine synthetase (GLU-S) and 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNPase). This effe...

journal_title：Brain research

authors： Honegger P,Guentert-Lauber B

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Metabolites involved in one-carbon metabolism (OCM) may predict cognitive prognosis in dementia. The link between OCM, apolipoprotein E (APOE), and DNA methylation creates a biologically plausible mechanism of interaction. AIM:To assess OCM metabolites as predictors of 5-year cognitive prognosis in patients...

journal_title：Brain research

authors： Hildre AS,Solvang SH,Aarsland D,Midtun Ø,McCann A,Ervik AO,Nygård O,Ueland PM,Nordrehaug JE,Giil LM

更新日期：2020-01-01 00:00:00

abstract：:The effects of intracerebroventricular injections of 8-OH-DPAT (a 5-HT1A agonist; 3, 15 or 30 nmol) or GR46611 (a 5-HT1B/1D agonist; 3, 15 or 30 nmol) on feeding, drinking, preening and sleep-like behaviors were investigated in free-feeding (FF) pigeons. The effects of these 5-HT agonists on blood glucose and free fat...

journal_title：Brain research

authors： Da Silva RA,de Oliveira ST,Hackl LP,Spilere CI,Faria MS,Marino-Neto J,Paschoalini MA

更新日期：2004-11-12 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the largest health problems in the United States and affects both cognitive and motor function. Although weakness is common in TBI patients, few studies have demonstrated a reduction in strength in models of brain injury. We have developed a behavioral method to measure volitiona...

journal_title：Brain research

authors： Pruitt D,Hays S,Schmid A,Choua C,Kim L,Trieu J,Kilgard MP,Rennaker RL 2nd

更新日期：2014-09-25 00:00:00

abstract：:Neovascularization within syngeneic rat fetal neocortical grafts transplanted into a previously prepared cavity in the cerebral cortex was studied 1 to 3 months after transplantation, utilizing scanning electron microscopy of vascular corrosion casts. The grafts were easily identified and the outer surface of the graf...

journal_title：Brain research

authors： Miyoshi Y,Date I,Ohmoto T

更新日期：1995-05-29 00:00:00

abstract：:Chemotherapy-induced pain is the most common treatment-limiting complication encountered by cancer patients receiving taxane-, vinca alkaloid- or platin-based chemotherapy. Several lines of evidence indicate that activation of pro-inflammatory cascades involving the release of cytokines including tumor necrosis factor...

journal_title：Brain research

authors： Cata JP,Weng HR,Dougherty PM

更新日期：2008-09-10 00:00:00

abstract：:Nitric oxide (NO) is an endothelium-derived relaxing factor and its main mechanism of action is activation of soluble guanylyl cyclase. NO and NO-related compounds have been reported to affect several neuronal functions in the central nervous system. In this study, we investigated the effects of NO donors (sodium nitr...

journal_title：Brain research

authors： Suzuki T,Nakajima K,Fujimoto K,Fujii T,Kawashima K

更新日期：1997-06-20 00:00:00

abstract：:Normal adult albino and Sprague-Dawley rats, under intraperitoneal Nembutal anesthesia, were used to demonstrate enzymatic activity in the choroid plexus and ventricular ependyma. The brain tissues were perfused or immersed with cold 2% glutaraldehyde and 8% sucrose in 0.1 M cacodylate buffer (pH 7.2-7.4) for 30 min a...

journal_title：Brain research

authors： Masuzawa T,Saito T,Sato F

更新日期：1981-10-19 00:00:00

abstract：:The dorsal root ganglia (DRG) have been identified as the target tissue in diabetic somatosensory neuropathy. It has been reported that, in the chronically diabetic state, DRG sensory neurons may undergo morphological changes. In this study, we examined the effect of zenarestat, an aldose reductase inhibitor, on the m...

journal_title：Brain research

authors： Shimoshige Y,Minoura K,Matsuoka N,Takakura S,Mutoh S,Kamijo M

更新日期：2009-01-09 00:00:00

abstract：:The influence of the inhibitory transmitter gamma-aminobutyric acid (GABA) on depolarizations elicited by the excitatory amino acid N-methyl-D-aspartate (NMDA) was tested in neurons of organotypic neocortical tissue cultures (newborn rat) and in CA3 neurons of the hippocampal slice (guinea pig). Drugs were applied thr...

journal_title：Brain research

authors： Walden J,Speckmann EJ,Bingmann D,Straub H

更新日期：1990-02-26 00:00:00

abstract：:The present study aimed to determine the kinetics of L-3, 4-dihydroxyphenylalanine (L-DOPA) uptake in an immortalised cell line of rat capillary cerebral endothelial cells (clones RBE 4 and RBE 4B), to define the type of inhibition produced by L-5-hydroxytryptophan (L-5-HTP), 2-aminobicyclo(2,2,1)-heptane-2-carboxylic...

journal_title：Brain research

authors： Gomes P,Soares-da-Silva P

更新日期：1999-05-22 00:00:00

abstract：:The binding of the adenosine receptor agonists, [3H]N-ethylcarboxamidoadenosine (NECA) and [3H]cyclohexyladenosine (CHA) to membrane preparations and to cryostat sections of the rat brain was examined. The xanthine derivative, 1,3-dipropyl-8-cyclopentylxanthine (DPCPX) was ca. 500-fold more effective at A1 than at A2 ...

journal_title：Brain research

authors： Lee KS,Reddington M

更新日期：1986-03-19 00:00:00

abstract：:The reversible blockade of geniculate PGO waves was carried out by localized cooling of the ponto-geniculate pathways during paradoxical sleep in chronic cats. In parallel, long-term recordings of unit activity were performed in non-specific visuooculomotor thalamic structures where no PGO waves occurred. Blockade of ...

journal_title：Brain research

authors： Laurent JP,Rondouin G,Benita M,Jouvet M

更新日期：1977-12-02 00:00:00

abstract：:Body temperature changes and heat shock protein (HSP-72) induction in the caudate nucleus were studied in female C57BL/6N mice pretreated with ibogaine (50 mg/kg) and sacrificed 48 h. after a single dose of methamphetamine (20 mg/kg). Methamphetamine injection resulted in hyperthermia and induced HSP-72 expression, wh...

journal_title：Brain research

authors： Yu X,Imam SZ,Newport GD,Slikker W Jr,Ali SF

更新日期：1999-03-27 00:00:00

abstract：:The present study combined masked priming with electrophysiological recordings to investigate orthographic priming effects with nonword targets. Targets were pronounceable nonwords (e.g., STRENG) or consonant strings (e.g., STRBNG), that both differed from a real word by a single letter substitution (STRONG). Targets ...

journal_title：Brain research

authors： Massol S,Midgley KJ,Holcomb PJ,Grainger J

更新日期：2011-04-22 00:00:00

abstract：:The preferential loss of GABAergic neurons in neocortex slab cultures after exposure to hypoxia was reinvestigated and confirmed using an improved morphometric analysis based on stereological principles. This preferential cell loss could be attenuated by treating the hypoxic slab cultures with the N-methyl-D-aspartate...

journal_title：Brain research

authors： Romijn HJ

更新日期：1989-10-30 00:00:00

abstract：:Dysfunction in the hypothalamic GABAergic system has been implicated in panic syndrome in humans. Furthermore, several studies have implicated the hypothalamus in the elaboration of pain modulation. Panic-prone states are able to be experimentally induced in laboratory animals to study this phenomenon. The aim of the ...

journal_title：Brain research

authors： Freitas RL,Uribe-Mariño A,Castiblanco-Urbina MA,Elias-Filho DH,Coimbra NC

更新日期：2009-12-11 00:00:00

abstract：:Cajal-Retzius (CR) cells of the mammalian neocortex co-express the extracellular matrix protein Reelin and p73, a transcription factor involved in cell death and survival. Most neocortical CR cells derive from the cortical hem, with minor additional sources. We analyzed the distribution of Reelin and p73 immunoreactiv...

journal_title：Brain research

authors： Cabrera-Socorro A,Hernandez-Acosta NC,Gonzalez-Gomez M,Meyer G

更新日期：2007-02-09 00:00:00