Collateral branching in axonal projections to spinal cord from paramedian reticular nucleus neurons.

Abstract:

:Experiments were done in cats to identify neurons in the paramedian reticular nucleus (PRN) sending collateral axons to the region of the intermediolateral nucleus (IML) at different levels of the thoracic cord by using lectin-conjugated horseradish peroxidase (HRP) and double-labeling fluorochrome histochemistry to retrogradely label PRN neurons. Injections of Fast blue (FB) into the spinal cord at the T2 level centered in the region of the IML were coupled with injections of Nuclear yellow (NY) into the ipsilateral cord at either the T4 or T7 levels centered in the region of the IML. Neurons in the PRN retrogradely labeled after diffusion of HRP into the region of the IML at the T2 level were observed throughout the rostrocaudal extent of the ventral PRN. In addition, a few labeled neurons were noted in the ventral portion of the dorsal PRN. About 40% of the neurons in the PRN which were labeled with FB after an injection at the T2 level were also labeled with NY injected into the cord in further caudal segments. These data suggest that the PRN may exert its influence on the cardiovascular system partly through collateral axonal branches to widely separated populations of sympathetic preganglionic neurons in different spinal segmental levels.

journal_name

Brain Res

journal_title

Brain research

authors

Elisevich K,Caverson MM,Flumerfelt BA,Hrycyshyn AW,Ciriello J

doi

10.1016/0006-8993(87)90377-5

subject

Has Abstract

pub_date

1987-04-07 00:00:00

pages

227-32

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(87)90377-5

journal_volume

408

pub_type

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