Characterization of glucagon-like peptide-1-(7-36)amide in the hypothalamus.

abstract：:cGMP was proposed to be the agent which directly opens the light-sensitive channel in Limulus ventral photoreceptors. However, the light-sensitive rhabdomeral-lobe (R-lobe) is not uniformly responsive to cGMP injection; that is, there are 'hot spots' of sensitivity. A potent phosphodiesterase which rapidly hydrolyses ...

journal_title：Brain research

authors： Feng JJ,Frank TM,Fein A

更新日期：1991-06-28 00:00:00

abstract：:In seven female alpha-chloralose-anesthetized cats, 52 lateral thalamic neurons were tested with noxious distension of the urinary bladder, the distal colon and the lower esophagus. In addition, the neurons were characterized with innocuous and noxious mechanical stimulation of the skin and deep structures. Of the 52 ...

journal_title：Brain research

authors： Horn AC,Vahle-Hinz C,Brüggemann J,Petersen M,Kniffki KD

更新日期：1999-12-18 00:00:00

abstract：:Administration of methyl palmoxirate (MP), an inhibitor of fatty acid oxidation, stimulates eating behavior in rats. Fos immunohistochemistry was used to determine neural pathways that may play a role in the eating response to MP. The number of cells showing Fos-like immunoreactivity (Fos-li) was quantified by compute...

journal_title：Brain research

authors： Horn CC,Friedman MI

更新日期：1998-01-19 00:00:00

abstract：:Interest in the role of membrane lipids in Schwann cell function prompted this study of lipid antigens on myelin- and non-myelin forming Schwann cells. Using the monoclonal antibodies 07, which recognises galactocerebroside, 08, 09 and 011, the distribution and time course of expression of the 4 membrane lipids have b...

journal_title：Brain research

authors： Eccleston PA,Mirsky R,Jessen KR,Sommer I,Schachner M

更新日期：1987-10-01 00:00:00

abstract：:Habituation kinetics were found to vary considerably in different polysynaptic pathways of the brain stem in man. The exteroceptive reflex of the digastric muscle habituates markedly, even for stimuli repeated at 1-min intervals. The second component of the blink reflex habituates for intervals below about 8 sec, but ...

journal_title：Brain research

authors： Desmedt JE,Godaux E

更新日期：1976-04-16 00:00:00

abstract：:The present paper examines the hypothesis that the long latency EMG activity produced by muscle stretch is the result of long loop reflex pathways involved in the control of limb stiffness. We recorded the cerebral responses and late EMG activity in agonist and antagonist muscles following sudden stretch of the wrist ...

journal_title：Brain research

authors： Goodin DS,Aminoff MJ

更新日期：1992-08-28 00:00:00

abstract：:Voltage-activated calcium channel currents were recorded from differentiated human neuroblastoma cells. SK-N-SH-SY5Y (SH-SY5Y) line, using patch-clamp techniques. Experimental solutions were designed to suppress sodium and potassium channel currents, and barium ions were used as the charge carrier. Two distinct types ...

journal_title：Brain research

authors： Reuveny E,Narahashi T

更新日期：1993-02-12 00:00:00

abstract：:Swimmeret mechanostimulation initiates an abdominal extension program which includes flexion inhibition. Agonists and antagonists were used to examine the GABAergic nature of inhibitory responses recorded intracellularly from a flexion producing interneuron (FPI 303) and flexor motor neuron (f3) pair, and extracellula...

journal_title：Brain research

authors： Kotak VC,Page CH

更新日期：1991-01-11 00:00:00

abstract：:Acute and repeated exposure to cocaine induces long-lasting alterations in neural networks that underlie compulsive drug seeking and taking. Cocaine exposure triggers complex adaptations in the brain that are mediated by dynamic patterns of gene expression that are translated into enduring changes. Recently, epigeneti...

journal_title：Brain research

authors： Sadri-Vakili G

更新日期：2015-12-02 00:00:00

abstract：:We have previously shown that the HSV-2 anti-apoptotic protein ICP10PK is delivered by the replication incompetent virus mutant DeltaRR and prevents kainic acid (KA)-induced epileptiform seizures and neuronal cell loss in the mouse and rat models of temporal lobe epilepsy. The present studies used DeltaRR and the ICP1...

journal_title：Brain research

authors： Gober MD,Laing JM,Thompson SM,Aurelian L

更新日期：2006-11-13 00:00:00

abstract：:The effects of 5-hydroxytryptamine (5-HT) on lateral horn cells contained in thin in vitro slices of neonatal rat spinal cord were investigated by means of intracellular recording techniques. Superfusion of 5-HT (1-100 microM) to lateral horn cells caused a concentration-dependent membrane depolarization leading to, i...

journal_title：Brain research

authors： Ma RC,Dun NJ

更新日期：1986-01-01 00:00:00

abstract：:Our previous studies have indicated that oxygen radicals, produced during reoxygenation following short-term arterial hypoxia, lead to sustained suppression of cerebral arteriolar responses to N-methyl-D-aspartate (NMDA). However, whether arteriolar dilator responses to NMDA are reduced during arterial hypoxia has nev...

journal_title：Brain research

authors： Bari F,Thore CR,Louis TM,Busija DW

更新日期：1998-01-12 00:00:00

abstract：:Rat hippocampal slices were incubated with [3H]uridine in vitro to analyze the metabolism of nuclear RNA and the RNA precursor fractions. Labeling of total nuclear RNA was linear for 4 h of incubation and proportional to the concentration of labeled uridine in the incubation medium. Addition of 3.5 X 10(-8) M corticos...

journal_title：Brain research

authors： Dokas LA,Liauw A

更新日期：1984-07-23 00:00:00

abstract：:Transient global cerebral ischemia has been shown to induce marked changes in the polyamine pathway with a significant increase in putrescine, the product of the ornithine decarboxylase reaction. This study examined the relationship between tissue and extracellular polyamines and regional cerebral blood flow and brain...

journal_title：Brain research

authors： Başkaya MK,Rao AM,Dogan A,Donaldson D,Gellin G,Dempsey RJ

更新日期：1997-01-09 00:00:00

abstract：:Placental Opioid-Enhancing Factor (POEF) is a substance found in amniotic fluid (AF) that, when ingested, potentiates opioid-mediated, but not non-opioid-mediated, hypoalgesia. Vaginal-cervical stimulation (VCS) produces a stimulus-bound, partially opioid-mediated hypoalgesia that previous research has shown to be pot...

journal_title：Brain research

authors： Hoey RF,Hurley SW,Daniels D,Kristal MB

更新日期：2011-02-28 00:00:00

abstract：:Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system. We have investigated the effects of NT incubation with rat neostriatal slices on calcium/calmodulin (Ca/CaM)-dependent protein phosphorylation. Slices were incubated with NT (5 or 50 nM) fo...

journal_title：Brain research

authors： Kasckow J,Cain ST,Nemeroff CB

更新日期：1991-04-05 00:00:00

abstract：:We studied the short- and long-term epileptogenic effects of massed stimulation (MS) of the piriform cortex. Sprague-Dawley rats with electrodes implanted bilaterally in the anterior piriform cortex and the dorsal and ventral hippocampi underwent MS: electrical stimulation of the left piriform cortex every 5 min for 6...

journal_title：Brain research

authors： Timofeeva OA,Peterson GM

更新日期：1997-04-18 00:00:00

abstract：:The innervation of the tensor tympani muscle of the middle ear in Macaca fascicularis (cynomolgus monkey) was studied using the horseradish peroxidase (HRP) neural tracing technique. A compact column of small trigeminal motoneurons was labeled ipsilaterally following intramuscular application of HRP to the tensor tymp...

journal_title：Brain research

authors： Gannon PJ,Eden AR

更新日期：1987-02-24 00:00:00

abstract：:To date, few treatment strategies applying cellular transplantation to the chronically injured spinal cord have yielded significant functional improvement in animal experiments. Here we report that significant improvement of locomotor function was achieved in rats with chronic spinal cord injury (SCI) by the applicati...

journal_title：Brain research

authors： Zhang SX,Huang F,Gates M,Holmberg EG

更新日期：2012-05-25 00:00:00

abstract：:This study examines directly the effects on serotonin release of varying brain tryptophan levels within the physiologic range. It also addresses possible interactions between tryptophan availability and frequency of membrane depolarization in controlling serotonin release. We demonstrate that reducing tryptophan level...

journal_title：Brain research

authors： Schaechter JD,Wurtman RJ

更新日期：1990-11-05 00:00:00

abstract：:Previous studies have shown that within 24 h after ischemic insult, gerbils exhibit an increase in locomotor activity. Because activity gradually diminishes to normal levels with repeated testing, it has been argued that this behavior represents a reversible or transient effect of ischemia. The present study challenge...

journal_title：Brain research

authors： Babcock AM,Baker DA,Lovec R

更新日期：1993-10-22 00:00:00

abstract：:The aim of this investigation was to determine whether an ingredient of green tea, epigallocatechin gallate (EGCG) could attenuate oxidative stress-induced degeneration of the retina as occurs in age-related macular degeneration (AMD) and glaucoma. Initial in vitro studies on brain membranes showed that EGCG was appro...

journal_title：Brain research

authors： Zhang B,Osborne NN

更新日期：2006-12-08 00:00:00

abstract：:The present study examines age-related changes in the subcellular localization of cathepsin B (cath B) and cathepsin D (cath D), as well as morphological features of the cathepsin-immunoreactive (ir) neurons in rat cerebral cortex. Sprague-Dawley rats were studied at 3 and 26 months. By immunoelectron microscopy cath ...

journal_title：Brain research

authors： Jung H,Lee EY,Lee SI

更新日期：1999-10-09 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs) react rapidly to brain and spinal cord injuries. This reaction is characterized by the retraction of cell processes, cell body swelling and increased expression of the NG2 chondroitin sulfate proteoglycan. Reactive OPCs rapidly divide and accumulate surrounding the injury site wh...

journal_title：Brain research

authors： Levine J

更新日期：2016-05-01 00:00:00

abstract：:Nordihydroguaiaretic acid (NDGA) is a powerful antioxidant and/or lipoxygenase (LOX) inhibitor which is isolated from Larrea tridentate. NDGA has been shown to have neuroprotective effects both in vitro and in vivo experiments. However, little is known regarding NDGA's protective mechanism in ischemia/reperfusion (I/R...

journal_title：Brain research

authors： Liu Y,Wang H,Zhu Y,Chen L,Qu Y,Zhu Y

更新日期：2012-03-22 00:00:00

abstract：:Previous studies have suggested that cardiovascular responses elicited by injection of glycine into the nucleus tractus solitarii (NTS) depend upon interactions between glycinergic and cholinergic neuronal elements in NTS. Release of acetylcholine in response to glycine is one such interaction that has been shown in s...

journal_title：Brain research

authors： Talman WT,Wellendorf L,Martinez D,Ellison S,Li X,Cassell M,Ohta H

更新日期：1994-07-11 00:00:00

abstract：:To characterize optical responses (ORs) evoked by white matter (WM) stimulation in slices of rat visual cortex (VC) stained with voltage sensitive dyes, time course of ORs in each layer was investigated by recording ORs with a linearly aligned photodiode array, and the spatial patterns of the ORs at specified time aft...

journal_title：Brain research

authors： Tanifuji M,Yamanaka A,Sunaba R,Terakawa S,Toyama K

更新日期：1996-10-28 00:00:00

abstract：:The effects of pentylenetetrazol (PTZ) following induction of long-term potentiation (LTP) on population spikes in CA1 of hippocampal slices were investigated. Population spikes were evoked by activation of Schaffer collaterals with a range of stimulation intensities. LTP was induced using θ-pattern primed burst...

journal_title：Brain research

authors： Omrani A,Fathollahi Y,Mohajerani HR,Semnanian S

更新日期：2000-09-22 00:00:00

abstract：:This review provides a snapshot of the current ethical issues related to research with human brain organoids. The issues fall into the following main themes: research oversight; human biomaterials procurement and donor consent; translational delivery; animal research; and organoid consciousness and moral status. Each ...

journal_title：Brain research

authors： Hyun I,Scharf-Deering JC,Lunshof JE

更新日期：2020-04-01 00:00:00

abstract：:In nondiabetic animals, estrogen has been shown to provide significant neuroprotection in focal and transient forebrain ischemia models. However, that neuroprotection may be diminished or lost in the diabetic. In this study, we compared the level of brain damage in intact, ovariectomized (OVX) and 17beta-estradiol (E(...

journal_title：Brain research

authors： Santizo RA,Xu HL,Ye S,Baughman VL,Pelligrino DA

更新日期：2002-11-22 00:00:00